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The map label for this gene is nanK [H]

Identifier: 86749188

GI number: 86749188

Start: 2349091

End: 2350035

Strand: Direct

Name: nanK [H]

Synonym: RPB_2067

Alternate gene names: 86749188

Gene position: 2349091-2350035 (Clockwise)

Preceding gene: 86749187

Following gene: 86749189

Centisome position: 44.06

GC content: 73.33

Gene sequence:

>945_bases
ATGAGCGCGATCTTCGCCGTCGATCTAGGGGCCACCTGGCTGCGCACCGCGCGGGTCGCGCCGGACGGGCGATGGATCGA
CCGCAAGGCGCGGGTGCCGACGCCGGACGGCCCAGCCGAGGCGCGCAAACTGATCGAGACCGCCTGGCGGCGTGCCGGCT
GCGCCGAAGCGGTGGCGCTGGCGACCGCGCCGGAACTCGACAGCGATGGCGTGGTGCGGCGCTGGCCGAACCGGCGCGAC
TACGAAGGCGCGCCGCTGTTGACCGATGCGCTCCGCTGCGTCGCGAGGCTCGCGCTGTTCGACGACGCCACCGCGGCGGC
GCTGTCGGCGGATGATGTCGACGGCGCCGCGGACGCGATCACGCTATGCCTGAGCATCGGCAGCGGCATCGGCGGCGGCG
TCGTCATCGCGGGGCGGCCGCTCGTGGGCGCGCATCACGCGGCGATGGATGCCGGCCACATGCCGGTGCCGTCCGCCGCC
GGCCTGCGATGCGCGTGCGGCCGCGACGGCTGCCTGCAGGCGGTCGCCTCCGGCGGGGCATTGCAACGGCACGGGGGCGG
CGCTCTGTTCGGCGATGCGCGCGCAGAGCCGGCCTTGCATCGCGCCACCGCCGCGCTGGCGGAGGCGTTGGCGATCCTGC
AGGCACTATTCGATCCGGAACGCGTGGTGATCGCGGGCGGCCTCGGCCTGTCGCCGCTGTTCGACCGGATCGCGGCCGAA
TTGAAAAGAAGCGGCGTCGCGCTCGCGATCGCGCCGCATCATCATGGCGACGATGCCGCGCTGGTCGGCGCGGCGATCGG
TCTGGCGCGGGGCCTCGCGCCGCGCGCGTCAACCTCGGCAGCAATATCCCCACCAGCAGCGAGAGGCGATCCACGATGCA
AGGTCAGTTCTCCGAACGGATACCAGCCTGGCCGCGTTTCGACGACGCGGACGAGCGGCGCCTGA

Upstream 100 bases:

>100_bases
TGCGACATTTTCATCGCTGCGTCCGCGCCGGCGCGGACGAGGAAGCCGCCGCGCTGCGGTTCGCCGCCGCGCTCGGCGGC
GCCTTGCGGGAGGCGGCGGC

Downstream 100 bases:

>100_bases
TCGAGGTGCTGCAGTCGCGCCGGTGGTGGCGCGGCAACGGCGGCATCGGCGACGCGTTCGAAGCCGCCTTCGCGGACTCG
CTCGGCGCGGCGCATGTCCG

Product: ROK

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSAIFAVDLGATWLRTARVAPDGRWIDRKARVPTPDGPAEARKLIETAWRRAGCAEAVALATAPELDSDGVVRRWPNRRD
YEGAPLLTDALRCVARLALFDDATAAALSADDVDGAADAITLCLSIGSGIGGGVVIAGRPLVGAHHAAMDAGHMPVPSAA
GLRCACGRDGCLQAVASGGALQRHGGGALFGDARAEPALHRATAALAEALAILQALFDPERVVIAGGLGLSPLFDRIAAE
LKRSGVALAIAPHHHGDDAALVGAAIGLARGLAPRASTSAAISPPAARGDPRCKVSSPNGYQPGRVSTTRTSGA

Sequences:

>Translated_314_residues
MSAIFAVDLGATWLRTARVAPDGRWIDRKARVPTPDGPAEARKLIETAWRRAGCAEAVALATAPELDSDGVVRRWPNRRD
YEGAPLLTDALRCVARLALFDDATAAALSADDVDGAADAITLCLSIGSGIGGGVVIAGRPLVGAHHAAMDAGHMPVPSAA
GLRCACGRDGCLQAVASGGALQRHGGGALFGDARAEPALHRATAALAEALAILQALFDPERVVIAGGLGLSPLFDRIAAE
LKRSGVALAIAPHHHGDDAALVGAAIGLARGLAPRASTSAAISPPAARGDPRCKVSSPNGYQPGRVSTTRTSGA
>Mature_313_residues
SAIFAVDLGATWLRTARVAPDGRWIDRKARVPTPDGPAEARKLIETAWRRAGCAEAVALATAPELDSDGVVRRWPNRRDY
EGAPLLTDALRCVARLALFDDATAAALSADDVDGAADAITLCLSIGSGIGGGVVIAGRPLVGAHHAAMDAGHMPVPSAAG
LRCACGRDGCLQAVASGGALQRHGGGALFGDARAEPALHRATAALAEALAILQALFDPERVVIAGGLGLSPLFDRIAAEL
KRSGVALAIAPHHHGDDAALVGAAIGLARGLAPRASTSAAISPPAARGDPRCKVSSPNGYQPGRVSTTRTSGA

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787363, Length=299, Percent_Identity=30.1003344481605, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081733, Length=298, Percent_Identity=28.1879194630872, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790522, Length=250, Percent_Identity=29.2, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 31843; Mature: 31712

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIFAVDLGATWLRTARVAPDGRWIDRKARVPTPDGPAEARKLIETAWRRAGCAEAVAL
CCEEEEEECCHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
ATAPELDSDGVVRRWPNRRDYEGAPLLTDALRCVARLALFDDATAAALSADDVDGAADAI
HCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHH
TLCLSIGSGIGGGVVIAGRPLVGAHHAAMDAGHMPVPSAAGLRCACGRDGCLQAVASGGA
HHHHHHCCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHCCCC
LQRHGGGALFGDARAEPALHRATAALAEALAILQALFDPERVVIAGGLGLSPLFDRIAAE
EEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
LKRSGVALAIAPHHHGDDAALVGAAIGLARGLAPRASTSAAISPPAARGDPRCKVSSPNG
HHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
YQPGRVSTTRTSGA
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SAIFAVDLGATWLRTARVAPDGRWIDRKARVPTPDGPAEARKLIETAWRRAGCAEAVAL
CEEEEEECCHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
ATAPELDSDGVVRRWPNRRDYEGAPLLTDALRCVARLALFDDATAAALSADDVDGAADAI
HCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHH
TLCLSIGSGIGGGVVIAGRPLVGAHHAAMDAGHMPVPSAAGLRCACGRDGCLQAVASGGA
HHHHHHCCCCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHCCCC
LQRHGGGALFGDARAEPALHRATAALAEALAILQALFDPERVVIAGGLGLSPLFDRIAAE
EEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
LKRSGVALAIAPHHHGDDAALVGAAIGLARGLAPRASTSAAISPPAARGDPRCKVSSPNG
HHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
YQPGRVSTTRTSGA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA