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The map label for this gene is ybiC [H]

Identifier: 86748833

GI number: 86748833

Start: 1944970

End: 1946055

Strand: Direct

Name: ybiC [H]

Synonym: RPB_1710

Alternate gene names: 86748833

Gene position: 1944970-1946055 (Clockwise)

Preceding gene: 86748832

Following gene: 86748834

Centisome position: 36.48

GC content: 67.86

Gene sequence:

>1086_bases
ATGGTGACAATCAAGGTCGACCGACTGATCGGTTTCGTCGCCGAAGTGTTCGAGCGCGCCGGCTCCTCGAAAGAGGAGGC
GCGCCGGATCGGCAGCTATCTCACCACCGCCAATCTCACCGGCCACGACAGCCACGGCGTGATCCGCGTGCCTGTCTATA
TCCGCTGGCGCAATGCCGGCGCTGTGCATCCGGATCAGGTCGTCGGCGTGCCGGTCGACCTGCCCTCGCTGGCCGTGGTC
GACGGCAAGTACGGCTACGGCCAGACCGTCGGGCCGCAGGCGGTGCGGATCGGCATCGACAAGTGCAAGGCGCAGGGGCT
TTCGGCGGTCGGCCTGAAGAACGCCGGCCATATCGGCCGGATCGGCGACTGGGCGGAGATGGCGGCGGCCGAGGGGCTGG
TGTCGATCCATTTCGTCACTGCGGCTGGTTCGATCCTGGTCGCGCCCTATGGCGGCGTCGAGCGACGACTGTCGACCGCG
CCTTATTGCGTCGGCGTGCCGCGGCCGGGCGCTCCGCCGGTGGTGCTCGATTTTGCGACCTCGATCGTCGCCGAGGGCAA
GGTGCTGGTCGCGGCGCGCGGCGGCAAGCAACTGCCGAAGGGCGCGCTGATCAATCCCGACGGCACCTTCAGCGAAGACC
CCGCGACGCTGTATGGCCCGTTCGAGAAGGACGGTCCAATCAATCACGTCAACGGCGCCGGAGCGATCCGTGCGTTCGGC
GAGCACAAGGGCTCGGGGCTGGCGCTGATCTGCGAATTGCTCGGCGGCGCTTTGAGCGGCAACGGCGCCACAGGGCCGGA
CCGGCCGTTCGCCAACGGCATGTTCTCGATCTATGTCGATCCGCAGCGGATCGATCCCGAGCACGTGTTCGACGCCGAGG
TCACGCGCTACATCGATTACTTCAGGAGTGCGAAGACCACAGCCGGCACCGAAGCGGTGTTGATCCCCGGCGATCCGGAA
TTGCGCACCCGTGCCGAGCGCACCGCCAACGGCGTGCCCTTGTCCGACGACACCTGGGCCGCCATCGTCGCCACCGCGCG
CGAAGTCGGCGTCGCCGAGGCTGCGATTCAGGCGGCCGTGGCGTGA

Upstream 100 bases:

>100_bases
AAAAGCACGGCCGCAAAGGGAGGGCGACGATGATCGGGCAGCGCCGGGCAGCGCGGCAGGGCCGCGGCCGCAAGGTCACT
CTCCGCGAGCGTGCACCAAC

Downstream 100 bases:

>100_bases
TTTTCCGTCATTGCGAGAAGTGCCCGGACGGCGCAAAGCGCCGATCCGGGTGCTTCTCGCAATGACGGAGAGAGGATCTC
GATAACTCATAACTGACTGC

Product: malate/L-lactate dehydrogenase

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MVTIKVDRLIGFVAEVFERAGSSKEEARRIGSYLTTANLTGHDSHGVIRVPVYIRWRNAGAVHPDQVVGVPVDLPSLAVV
DGKYGYGQTVGPQAVRIGIDKCKAQGLSAVGLKNAGHIGRIGDWAEMAAAEGLVSIHFVTAAGSILVAPYGGVERRLSTA
PYCVGVPRPGAPPVVLDFATSIVAEGKVLVAARGGKQLPKGALINPDGTFSEDPATLYGPFEKDGPINHVNGAGAIRAFG
EHKGSGLALICELLGGALSGNGATGPDRPFANGMFSIYVDPQRIDPEHVFDAEVTRYIDYFRSAKTTAGTEAVLIPGDPE
LRTRAERTANGVPLSDDTWAAIVATAREVGVAEAAIQAAVA

Sequences:

>Translated_361_residues
MVTIKVDRLIGFVAEVFERAGSSKEEARRIGSYLTTANLTGHDSHGVIRVPVYIRWRNAGAVHPDQVVGVPVDLPSLAVV
DGKYGYGQTVGPQAVRIGIDKCKAQGLSAVGLKNAGHIGRIGDWAEMAAAEGLVSIHFVTAAGSILVAPYGGVERRLSTA
PYCVGVPRPGAPPVVLDFATSIVAEGKVLVAARGGKQLPKGALINPDGTFSEDPATLYGPFEKDGPINHVNGAGAIRAFG
EHKGSGLALICELLGGALSGNGATGPDRPFANGMFSIYVDPQRIDPEHVFDAEVTRYIDYFRSAKTTAGTEAVLIPGDPE
LRTRAERTANGVPLSDDTWAAIVATAREVGVAEAAIQAAVA
>Mature_361_residues
MVTIKVDRLIGFVAEVFERAGSSKEEARRIGSYLTTANLTGHDSHGVIRVPVYIRWRNAGAVHPDQVVGVPVDLPSLAVV
DGKYGYGQTVGPQAVRIGIDKCKAQGLSAVGLKNAGHIGRIGDWAEMAAAEGLVSIHFVTAAGSILVAPYGGVERRLSTA
PYCVGVPRPGAPPVVLDFATSIVAEGKVLVAARGGKQLPKGALINPDGTFSEDPATLYGPFEKDGPINHVNGAGAIRAFG
EHKGSGLALICELLGGALSGNGATGPDRPFANGMFSIYVDPQRIDPEHVFDAEVTRYIDYFRSAKTTAGTEAVLIPGDPE
LRTRAERTANGVPLSDDTWAAIVATAREVGVAEAAIQAAVA

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=357, Percent_Identity=36.6946778711485, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1790000, Length=348, Percent_Identity=24.1379310344828, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786727, Length=360, Percent_Identity=21.6666666666667, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17507179, Length=330, Percent_Identity=26.969696969697, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536633, Length=357, Percent_Identity=25.7703081232493, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45553211, Length=332, Percent_Identity=29.5180722891566, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24667912, Length=332, Percent_Identity=29.5180722891566, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24667904, Length=332, Percent_Identity=28.6144578313253, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24667908, Length=332, Percent_Identity=29.5180722891566, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24648360, Length=355, Percent_Identity=24.2253521126761, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 37623; Mature: 37623

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKVDRLIGFVAEVFERAGSSKEEARRIGSYLTTANLTGHDSHGVIRVPVYIRWRNAG
CEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCCCCEEEEEEEEEECCCC
AVHPDQVVGVPVDLPSLAVVDGKYGYGQTVGPQAVRIGIDKCKAQGLSAVGLKNAGHIGR
CCCCCCEEECCCCCCCEEEEECCCCCCCCCCCHHEEECHHHHHHCCCEEECCCCCCCCCC
IGDWAEMAAAEGLVSIHFVTAAGSILVAPYGGVERRLSTAPYCVGVPRPGAPPVVLDFAT
CCCHHHHHHHCCEEEEEEEEECCCEEEECCCCHHHHHCCCCEEEECCCCCCCCEEHHHHH
SIVAEGKVLVAARGGKQLPKGALINPDGTFSEDPATLYGPFEKDGPINHVNGAGAIRAFG
HHHHCCEEEEEECCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEECC
EHKGSGLALICELLGGALSGNGATGPDRPFANGMFSIYVDPQRIDPEHVFDAEVTRYIDY
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
FRSAKTTAGTEAVLIPGDPELRTRAERTANGVPLSDDTWAAIVATAREVGVAEAAIQAAV
HHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MVTIKVDRLIGFVAEVFERAGSSKEEARRIGSYLTTANLTGHDSHGVIRVPVYIRWRNAG
CEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCCCCEEEEEEEEEECCCC
AVHPDQVVGVPVDLPSLAVVDGKYGYGQTVGPQAVRIGIDKCKAQGLSAVGLKNAGHIGR
CCCCCCEEECCCCCCCEEEEECCCCCCCCCCCHHEEECHHHHHHCCCEEECCCCCCCCCC
IGDWAEMAAAEGLVSIHFVTAAGSILVAPYGGVERRLSTAPYCVGVPRPGAPPVVLDFAT
CCCHHHHHHHCCEEEEEEEEECCCEEEECCCCHHHHHCCCCEEEECCCCCCCCEEHHHHH
SIVAEGKVLVAARGGKQLPKGALINPDGTFSEDPATLYGPFEKDGPINHVNGAGAIRAFG
HHHHCCEEEEEECCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEECC
EHKGSGLALICELLGGALSGNGATGPDRPFANGMFSIYVDPQRIDPEHVFDAEVTRYIDY
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
FRSAKTTAGTEAVLIPGDPELRTRAERTANGVPLSDDTWAAIVATAREVGVAEAAIQAAV
HHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]