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The map label for this gene is lrp [H]

Identifier: 86748638

GI number: 86748638

Start: 1705990

End: 1706520

Strand: Direct

Name: lrp [H]

Synonym: RPB_1513

Alternate gene names: 86748638

Gene position: 1705990-1706520 (Clockwise)

Preceding gene: 86748635

Following gene: 86748642

Centisome position: 32.0

GC content: 64.03

Gene sequence:

>531_bases
ATGAGGGGGACGATTTGCCGCCCAGACCGCAACACGGGATTTCGCCGCGTGTCCAAGAGCCTCGATCAGATCGATCTCAA
GATCCTCCAGGAGATCCAGGAAGACGGCCGAATCACCAATGTCGAATTGGCGAAACGGGTCGGCATCTCGCCGCCGCCCT
GTCTGCGCCGCGTCCGGACGCTGGAGGAGGAGGGCTACATCCAGGGCTATCGCGGCCTGCTCGATCCGGCCCTGCTCGGC
TTCGACGTCACCGTGTTCGCCTCGGTGCATCTGGCGAGCCAGGCCGAAGCGGATCTGCGCGGCTTCGAGGAATTCGTGCG
CAACGAGCCGCTGGTCCGGGAATGCTGGATGCTGTCGGGCGAGGTGGATTTCATCCTGAAATGCGTGGCGCCGGACATGG
CGACATTCCAGAATTTCGTCGCGCATCTGACCGCGGCGCCGCATGTGCGCAACGTCCGGACCTCGCTGGTGCTGCGCAAT
TCGAAATACGCTCCCGCGGTGCCGCTGGAATTGAAGGCGGCGGCGACCTGA

Upstream 100 bases:

>100_bases
GCAAGATTTGCAACACGTATGTGCAGGATTTCCCACCGTGTTTGGCAAACGAGGTGTGATCATCGCGAAATAAAATTGCG
CAAGTTTGGACAAGTGCGTT

Downstream 100 bases:

>100_bases
GCGGACGCCACCGCAACGCCGTCAGCGCGAGCGGATGATCCTGTCGAGGCTGATCGGCCCGCCGCCCGCCGTCGCCAGAT
ACAGGCAGGCGAAGCAGAAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRGTICRPDRNTGFRRVSKSLDQIDLKILQEIQEDGRITNVELAKRVGISPPPCLRRVRTLEEEGYIQGYRGLLDPALLG
FDVTVFASVHLASQAEADLRGFEEFVRNEPLVRECWMLSGEVDFILKCVAPDMATFQNFVAHLTAAPHVRNVRTSLVLRN
SKYAPAVPLELKAAAT

Sequences:

>Translated_176_residues
MRGTICRPDRNTGFRRVSKSLDQIDLKILQEIQEDGRITNVELAKRVGISPPPCLRRVRTLEEEGYIQGYRGLLDPALLG
FDVTVFASVHLASQAEADLRGFEEFVRNEPLVRECWMLSGEVDFILKCVAPDMATFQNFVAHLTAAPHVRNVRTSLVLRN
SKYAPAVPLELKAAAT
>Mature_176_residues
MRGTICRPDRNTGFRRVSKSLDQIDLKILQEIQEDGRITNVELAKRVGISPPPCLRRVRTLEEEGYIQGYRGLLDPALLG
FDVTVFASVHLASQAEADLRGFEEFVRNEPLVRECWMLSGEVDFILKCVAPDMATFQNFVAHLTAAPHVRNVRTSLVLRN
SKYAPAVPLELKAAAT

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=42.3841059602649, Blast_Score=125, Evalue=1e-30,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=29.1390728476821, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 19721; Mature: 19721

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGTICRPDRNTGFRRVSKSLDQIDLKILQEIQEDGRITNVELAKRVGISPPPCLRRVRT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHH
LEEEGYIQGYRGLLDPALLGFDVTVFASVHLASQAEADLRGFEEFVRNEPLVRECWMLSG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
EVDFILKCVAPDMATFQNFVAHLTAAPHVRNVRTSLVLRNSKYAPAVPLELKAAAT
CHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCEECCCCC
>Mature Secondary Structure
MRGTICRPDRNTGFRRVSKSLDQIDLKILQEIQEDGRITNVELAKRVGISPPPCLRRVRT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHH
LEEEGYIQGYRGLLDPALLGFDVTVFASVHLASQAEADLRGFEEFVRNEPLVRECWMLSG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
EVDFILKCVAPDMATFQNFVAHLTAAPHVRNVRTSLVLRNSKYAPAVPLELKAAAT
CHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]