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The map label for this gene is bisC [C]

Identifier: 86748617

GI number: 86748617

Start: 1683063

End: 1685384

Strand: Reverse

Name: bisC [C]

Synonym: RPB_1492

Alternate gene names: 86748617

Gene position: 1685384-1683063 (Counterclockwise)

Preceding gene: 86748619

Following gene: 86748616

Centisome position: 31.61

GC content: 65.81

Gene sequence:

>2322_bases
ATGAATCACCCGAAGACGCTGACGGCGGCCCATTGGGGCCTTTATGAGATCCGCGACGCGATGACGGCCGAGGTTTCGAT
CCATCCTTTCGCGACGGATCCGAGCCCGTCGCCGATCGGCTTGCAGATGCTGGAGACGGCGCGGTCCGATTCGCGGGTTC
GGCGCCCTGCCGTGCGCAAGGGCTGGCTGGAGAACGGCCCGGCATCCCGCGGCCAACGCGGCCTCGAGCCGTTCGTCGAA
GTCGACTGGAGCGTCGCGCTCGACCTCGTGGCCCGCGAACTCGGCCGCGTGAAGCAGCAGCACGGCAATCAAGCGATCTT
CGGCGGCTCCTACGGCTGGTCCAGCGCCGGCCGCTTTCATCATGCCCAGAGCCAGGTCCACCGCTTCCTCAACTGCATCG
GCGGCTACGTCCGCCACCTCAATTCGTACAGCCTCGGCGTCGCTCACCCATTGCTGCCCTATCTGGTCGCGCCGATCGGC
GAGCTGATGATGACGCACAACGACTGGGACTCGCTGATCGAGCACTGCGAATTGTTCGTGACGTTCGGTGGCGTGCCGGC
CAAGAACGCCCAGATTTCGCAGGGCGGCACTGCCGAGCATCGTATTCCCGGAGCCCTCGCCCGGATGCAGCGCGCCGGCA
TCAAATTCGTGAACATCAGCCCGACCCGGAAAGATCTGGAGACCGGCGCCGACTTCGAATGGTGGCCGATCCGCCCGAAC
ACCGACACGGCGCTGATGCTGGCGCTGGCCTACGTGCTGGTCGAGGAGGGTTTGCACGACACCACGTTCCTCGCGACATA
CTGCGTCGGCTTCGAGGTTTTCCGGAACTATCTGCTCGGCCAGAAGGACGGCGTGCGCAAGACACCGGACTGGGCCGGAG
GCATCACCGGCATCGACCCGGAGCGGATTCGATCGCTGGCCCGGGAGATGGGCGCCAAGCGTTGCATGATCAACGCCGCG
TGGTCGTTGCAGCGCGCCCATCACGGCGAGCAGCCGTATTGGGCGCTGATCTCGCTCGCCGCGCTGGTCGGTCAGATCGG
CACGCCCGGCGGCGGCTTCGGTGTCGGCTATGGCGCCGAGAATCTATTGGGAAGTCCGCATGCGCGGATCAGCGGGCCCA
CCCTGCCCCAGGGCAGCAATGCGGTCGACAGTTTCATTCCGGTCGCGCGCATCGTCGACATGCTCGAGAGCCCGGGGCAG
CCTTTCACCTATTCGGGCAAGATCCATCACTATCCCGACGTCAAGCTGGTCTACTGGGCCGGCGGCAATCCGTTTCATCA
CCATCAGGACCTGACCCGACTCGTCAACGCCTGGCGGCTGCCCGACTCGGTGTTCGTGAACGAGCAGTTCTGGACTCCGC
TGGCGAAGATGGCCGACGTCGTCTTTCCCGCCACCACCGCGCTGGAGCGGGAGGACATCTTCTTCTCGCCCAAGGAGCAC
CTGATCGCCCCGATGAAGCAGGCGATTCCCCGCGTCGGAGAAGCCCGCGACGACTACGACATCTTCCGTGGCTTGTCCGA
CCGCCTCGGCGTCGACGCGGCGTTTTCCGAACACCGCGATGCGCGGCAATGGATCGAACATCTCTACATCGACTGGCGCG
AGCGGATCGCGGGCGACGGCGTGGCACTGCCGGACTTCGAATCCTTCTGGCACGGCGAGACCGTCGCGCTGCCTAAGCCC
TCGCGGCCGACCGTGATGCTGGAGGCCTTCCGCGACGATCCGCTGGCCCATCCGCTGGGAACGCCGTCCGGCAAGATCGA
GATCTATTCGGCGACGGTCGACGGGTTCGGTTACGCGGATTGCCCGGGCGGACACGCGACGTGGCTCGAACCGGCCGAAT
GGCTCGGAAGTCCGCTGGCGACCACCTATCCGCTGCACCTGATATCGGATCAGCCCTCGACGCGGCTTCACAGCCAGCTC
GATCATGGCCCGTTGAGCCGATCTCAGAAGATCCAGGGCCGCGAACCGGTCGACATCCATCCCGACGACGCCGACCGGCG
GGGCATCCGGACCGGCGACATCGTGCGGCTGTTCAACGCCCGCGGCTCGTGCCTGAGCGGTGCGAACGTGACTGCCAATG
TCGTAAGCGGGGTGGTACGCTTGTCGACGGGCGCATGGTTCGACCCACAGGATTGGAGCGGAAACCAGGTGCTGGAGAAG
CACGGCAACCCCAACGCGCTCACGGCCGATCTCGCCGCATCATCGTTTTCGCAAGGCTGTGCGGCGCAGACCTGCCTCGT
CGACATCGAGAAGTATCTCGACGCGGCACCGCCGGTCTCGGCCTTCGACACGCCGGACGGCGTGGCGAGCCTGGCGACAT
GA

Upstream 100 bases:

>100_bases
CGGGTTTCCTGCTGGCCTTACCGAAAGGAGGTGCTGGCTTTATGAAACAGCAACATCCGTCCGCATGATAGGGCCACGTA
GGTATCTCAGACGGATCCTG

Downstream 100 bases:

>100_bases
CGAACTGGCGGGCCGCGCCGCCGGCTTCAACACCTTTCGACCTGAATGAAAGAACACCATGAACGAGACCATCCTCAGCA
AAGAACTTCGCGAACTCGAT

Product: trimethylamine-N-oxide reductase (cytochrome c)

Products: Biotin. [C]

Alternate protein names: BDS reductase; BSO reductase [H]

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MNHPKTLTAAHWGLYEIRDAMTAEVSIHPFATDPSPSPIGLQMLETARSDSRVRRPAVRKGWLENGPASRGQRGLEPFVE
VDWSVALDLVARELGRVKQQHGNQAIFGGSYGWSSAGRFHHAQSQVHRFLNCIGGYVRHLNSYSLGVAHPLLPYLVAPIG
ELMMTHNDWDSLIEHCELFVTFGGVPAKNAQISQGGTAEHRIPGALARMQRAGIKFVNISPTRKDLETGADFEWWPIRPN
TDTALMLALAYVLVEEGLHDTTFLATYCVGFEVFRNYLLGQKDGVRKTPDWAGGITGIDPERIRSLAREMGAKRCMINAA
WSLQRAHHGEQPYWALISLAALVGQIGTPGGGFGVGYGAENLLGSPHARISGPTLPQGSNAVDSFIPVARIVDMLESPGQ
PFTYSGKIHHYPDVKLVYWAGGNPFHHHQDLTRLVNAWRLPDSVFVNEQFWTPLAKMADVVFPATTALEREDIFFSPKEH
LIAPMKQAIPRVGEARDDYDIFRGLSDRLGVDAAFSEHRDARQWIEHLYIDWRERIAGDGVALPDFESFWHGETVALPKP
SRPTVMLEAFRDDPLAHPLGTPSGKIEIYSATVDGFGYADCPGGHATWLEPAEWLGSPLATTYPLHLISDQPSTRLHSQL
DHGPLSRSQKIQGREPVDIHPDDADRRGIRTGDIVRLFNARGSCLSGANVTANVVSGVVRLSTGAWFDPQDWSGNQVLEK
HGNPNALTADLAASSFSQGCAAQTCLVDIEKYLDAAPPVSAFDTPDGVASLAT

Sequences:

>Translated_773_residues
MNHPKTLTAAHWGLYEIRDAMTAEVSIHPFATDPSPSPIGLQMLETARSDSRVRRPAVRKGWLENGPASRGQRGLEPFVE
VDWSVALDLVARELGRVKQQHGNQAIFGGSYGWSSAGRFHHAQSQVHRFLNCIGGYVRHLNSYSLGVAHPLLPYLVAPIG
ELMMTHNDWDSLIEHCELFVTFGGVPAKNAQISQGGTAEHRIPGALARMQRAGIKFVNISPTRKDLETGADFEWWPIRPN
TDTALMLALAYVLVEEGLHDTTFLATYCVGFEVFRNYLLGQKDGVRKTPDWAGGITGIDPERIRSLAREMGAKRCMINAA
WSLQRAHHGEQPYWALISLAALVGQIGTPGGGFGVGYGAENLLGSPHARISGPTLPQGSNAVDSFIPVARIVDMLESPGQ
PFTYSGKIHHYPDVKLVYWAGGNPFHHHQDLTRLVNAWRLPDSVFVNEQFWTPLAKMADVVFPATTALEREDIFFSPKEH
LIAPMKQAIPRVGEARDDYDIFRGLSDRLGVDAAFSEHRDARQWIEHLYIDWRERIAGDGVALPDFESFWHGETVALPKP
SRPTVMLEAFRDDPLAHPLGTPSGKIEIYSATVDGFGYADCPGGHATWLEPAEWLGSPLATTYPLHLISDQPSTRLHSQL
DHGPLSRSQKIQGREPVDIHPDDADRRGIRTGDIVRLFNARGSCLSGANVTANVVSGVVRLSTGAWFDPQDWSGNQVLEK
HGNPNALTADLAASSFSQGCAAQTCLVDIEKYLDAAPPVSAFDTPDGVASLAT
>Mature_773_residues
MNHPKTLTAAHWGLYEIRDAMTAEVSIHPFATDPSPSPIGLQMLETARSDSRVRRPAVRKGWLENGPASRGQRGLEPFVE
VDWSVALDLVARELGRVKQQHGNQAIFGGSYGWSSAGRFHHAQSQVHRFLNCIGGYVRHLNSYSLGVAHPLLPYLVAPIG
ELMMTHNDWDSLIEHCELFVTFGGVPAKNAQISQGGTAEHRIPGALARMQRAGIKFVNISPTRKDLETGADFEWWPIRPN
TDTALMLALAYVLVEEGLHDTTFLATYCVGFEVFRNYLLGQKDGVRKTPDWAGGITGIDPERIRSLAREMGAKRCMINAA
WSLQRAHHGEQPYWALISLAALVGQIGTPGGGFGVGYGAENLLGSPHARISGPTLPQGSNAVDSFIPVARIVDMLESPGQ
PFTYSGKIHHYPDVKLVYWAGGNPFHHHQDLTRLVNAWRLPDSVFVNEQFWTPLAKMADVVFPATTALEREDIFFSPKEH
LIAPMKQAIPRVGEARDDYDIFRGLSDRLGVDAAFSEHRDARQWIEHLYIDWRERIAGDGVALPDFESFWHGETVALPKP
SRPTVMLEAFRDDPLAHPLGTPSGKIEIYSATVDGFGYADCPGGHATWLEPAEWLGSPLATTYPLHLISDQPSTRLHSQL
DHGPLSRSQKIQGREPVDIHPDDADRRGIRTGDIVRLFNARGSCLSGANVTANVVSGVVRLSTGAWFDPQDWSGNQVLEK
HGNPNALTADLAASSFSQGCAAQTCLVDIEKYLDAAPPVSAFDTPDGVASLAT

Specific function: This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source. It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI145693196, Length=776, Percent_Identity=40.979381443299, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI87081994, Length=784, Percent_Identity=38.5204081632653, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI1787231, Length=782, Percent_Identity=39.1304347826087, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI87081797, Length=755, Percent_Identity=32.1854304635762, Blast_Score=289, Evalue=5e-79,
Organism=Escherichia coli, GI1787870, Length=735, Percent_Identity=31.5646258503401, Blast_Score=277, Evalue=2e-75,
Organism=Escherichia coli, GI171474008, Length=725, Percent_Identity=31.0344827586207, Blast_Score=254, Evalue=2e-68,
Organism=Escherichia coli, GI3868721, Length=673, Percent_Identity=22.5854383358098, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 84829; Mature: 84829

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPKTLTAAHWGLYEIRDAMTAEVSIHPFATDPSPSPIGLQMLETARSDSRVRRPAVRK
CCCCCCCHHHHCCHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHH
GWLENGPASRGQRGLEPFVEVDWSVALDLVARELGRVKQQHGNQAIFGGSYGWSSAGRFH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHH
HAQSQVHRFLNCIGGYVRHLNSYSLGVAHPLLPYLVAPIGELMMTHNDWDSLIEHCELFV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEE
TFGGVPAKNAQISQGGTAEHRIPGALARMQRAGIKFVNISPTRKDLETGADFEWWPIRPN
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHCCCCCEEECCCCC
TDTALMLALAYVLVEEGLHDTTFLATYCVGFEVFRNYLLGQKDGVRKTPDWAGGITGIDP
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
ERIRSLAREMGAKRCMINAAWSLQRAHHGEQPYWALISLAALVGQIGTPGGGFGVGYGAE
HHHHHHHHHHCHHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
NLLGSPHARISGPTLPQGSNAVDSFIPVARIVDMLESPGQPFTYSGKIHHYPDVKLVYWA
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCEEEECCCEEEEEEC
GGNPFHHHQDLTRLVNAWRLPDSVFVNEQFWTPLAKMADVVFPATTALEREDIFFSPKEH
CCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCHHHCCCCCCEECCHHH
LIAPMKQAIPRVGEARDDYDIFRGLSDRLGVDAAFSEHRDARQWIEHLYIDWRERIAGDG
HHHHHHHHHHHHCCCCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VALPDFESFWHGETVALPKPSRPTVMLEAFRDDPLAHPLGTPSGKIEIYSATVDGFGYAD
CCCCCHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCC
CPGGHATWLEPAEWLGSPLATTYPLHLISDQPSTRLHSQLDHGPLSRSQKIQGREPVDIH
CCCCCCCCCCHHHHCCCCCCHHCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PDDADRRGIRTGDIVRLFNARGSCLSGANVTANVVSGVVRLSTGAWFDPQDWSGNQVLEK
CCCCCCCCCCCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
HGNPNALTADLAASSFSQGCAAQTCLVDIEKYLDAAPPVSAFDTPDGVASLAT
CCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNHPKTLTAAHWGLYEIRDAMTAEVSIHPFATDPSPSPIGLQMLETARSDSRVRRPAVRK
CCCCCCCHHHHCCHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHH
GWLENGPASRGQRGLEPFVEVDWSVALDLVARELGRVKQQHGNQAIFGGSYGWSSAGRFH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHH
HAQSQVHRFLNCIGGYVRHLNSYSLGVAHPLLPYLVAPIGELMMTHNDWDSLIEHCELFV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEE
TFGGVPAKNAQISQGGTAEHRIPGALARMQRAGIKFVNISPTRKDLETGADFEWWPIRPN
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHCCCCCEEECCCCC
TDTALMLALAYVLVEEGLHDTTFLATYCVGFEVFRNYLLGQKDGVRKTPDWAGGITGIDP
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
ERIRSLAREMGAKRCMINAAWSLQRAHHGEQPYWALISLAALVGQIGTPGGGFGVGYGAE
HHHHHHHHHHCHHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
NLLGSPHARISGPTLPQGSNAVDSFIPVARIVDMLESPGQPFTYSGKIHHYPDVKLVYWA
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCEEEECCCEEEEEEC
GGNPFHHHQDLTRLVNAWRLPDSVFVNEQFWTPLAKMADVVFPATTALEREDIFFSPKEH
CCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCHHHCCCCCCEECCHHH
LIAPMKQAIPRVGEARDDYDIFRGLSDRLGVDAAFSEHRDARQWIEHLYIDWRERIAGDG
HHHHHHHHHHHHCCCCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VALPDFESFWHGETVALPKPSRPTVMLEAFRDDPLAHPLGTPSGKIEIYSATVDGFGYAD
CCCCCHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCC
CPGGHATWLEPAEWLGSPLATTYPLHLISDQPSTRLHSQLDHGPLSRSQKIQGREPVDIH
CCCCCCCCCCHHHHCCCCCCHHCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PDDADRRGIRTGDIVRLFNARGSCLSGANVTANVVSGVVRLSTGAWFDPQDWSGNQVLEK
CCCCCCCCCCCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
HGNPNALTADLAASSFSQGCAAQTCLVDIEKYLDAAPPVSAFDTPDGVASLAT
CCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: Reduction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7733660 [H]