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The map label for this gene is cobT [H]

Identifier: 86747868

GI number: 86747868

Start: 834384

End: 835439

Strand: Direct

Name: cobT [H]

Synonym: RPB_0742

Alternate gene names: 86747868

Gene position: 834384-835439 (Clockwise)

Preceding gene: 86747861

Following gene: 86747869

Centisome position: 15.65

GC content: 72.82

Gene sequence:

>1056_bases
ATGCAGACCGACACTCTCGTTGCCTGGCAGGCGCCGCCGATCATGCCGGTGGACCGCGCCCTGCGCGCCGCCCTGCGGGC
GCGGGTCGACGGCAAGGCCAAGCCGCCGGGCTCGCTCGGCCGGATCGAGCATCTCGCGGTCGAACTCGGCGCGATGCGGC
ATCCGGCGCCGCCGCGCGGCGACAATGCGGTGCTGATGGTGTTCGCCGGCGATCACGGGCTGACCGAAGAGGGCGTCTCG
CAATATCCGTCCGCCGTGACGGTGGCGATGGTGATGACCTATCTGGCCGGCCGGGCCTGCGCCAATGCGTTCGCCGCCGC
GACCCATGTCGACGTCCGGGTGATCGACGCCGGCGTCGCGGCCGACCTGCCGGCGCACCCCGACCTGATCGACGCCAAGG
TGCGCAAAGGCACCGGCAACGCGGCGTGCGAGCCGGCGATGACCATCGCACAGGCCGCGCTGGCGCTGGCCCGGGGCAGC
GAGCTGGCAATCGCCGAGATCAAGGCCGGCGCCGACATCATCGCGCTCGGCGAGATGGGCATCGGCAACACCGCGTCGTC
GTCGCTGCTGCTGCATCGGCTGGCGCCGGCGCCGCTCGATCATTGCATCGGCGTCGGCGCCGGACAGGACGCGCCCGGCC
TGGCGAAGAAGCGCGCCGCGATCGAGAAGGCCGCCGCGCGCAGCGATGCGACCGCGCCGTTCGAGGTGCTGTGCGAATTC
GGCGGGCTGGAAATCGCCATGATGGCCGGCGCCGTGCTCGGCGCGGCGTCGCAGCGCCGCCCGGTGATCATCGACGGCTT
CATCGCCACCGCCGCGGCGCTGCTCGCGGTCCGGCTTGCGCCGGACGCGCGCGGCTATTGCGTGTTCGCGCATCGCTCTG
CCGAGCGCGGCCACAGCCTCGCGCTCGAGGCGCTGCAGGCGTCGCCGCTGCTGGATCTCGACATGCGGCTCGGCGAAGGC
ACCGGCGCTATTCTGGCGGTGCCGCTGGTCCGCGCCGCATCGCGGCTGCTGACCGACGTCGCCGATCTGTCCGACGTGCT
GGCGGGCAAACTGTGA

Upstream 100 bases:

>100_bases
GCTAGCTGTGGCATCCGTCGCGGTCAACCACGCGAAGGTAATGTTGACGTGCGGCCCCGGGACGAGTCAGTTGCCCGGCG
TCACGAAGCAGGGGACCCCG

Downstream 100 bases:

>100_bases
GCGCTCTCGAACACAAGGTGGATGCCAAGGTGGATGCCATGTCCGACGCGAAGGCGACCGTTGCCGCCGCCCCCAAGCCG
CCGGTGTTCGACCCGGCGTT

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQTDTLVAWQAPPIMPVDRALRAALRARVDGKAKPPGSLGRIEHLAVELGAMRHPAPPRGDNAVLMVFAGDHGLTEEGVS
QYPSAVTVAMVMTYLAGRACANAFAAATHVDVRVIDAGVAADLPAHPDLIDAKVRKGTGNAACEPAMTIAQAALALARGS
ELAIAEIKAGADIIALGEMGIGNTASSSLLLHRLAPAPLDHCIGVGAGQDAPGLAKKRAAIEKAAARSDATAPFEVLCEF
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALLAVRLAPDARGYCVFAHRSAERGHSLALEALQASPLLDLDMRLGEG
TGAILAVPLVRAASRLLTDVADLSDVLAGKL

Sequences:

>Translated_351_residues
MQTDTLVAWQAPPIMPVDRALRAALRARVDGKAKPPGSLGRIEHLAVELGAMRHPAPPRGDNAVLMVFAGDHGLTEEGVS
QYPSAVTVAMVMTYLAGRACANAFAAATHVDVRVIDAGVAADLPAHPDLIDAKVRKGTGNAACEPAMTIAQAALALARGS
ELAIAEIKAGADIIALGEMGIGNTASSSLLLHRLAPAPLDHCIGVGAGQDAPGLAKKRAAIEKAAARSDATAPFEVLCEF
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALLAVRLAPDARGYCVFAHRSAERGHSLALEALQASPLLDLDMRLGEG
TGAILAVPLVRAASRLLTDVADLSDVLAGKL
>Mature_351_residues
MQTDTLVAWQAPPIMPVDRALRAALRARVDGKAKPPGSLGRIEHLAVELGAMRHPAPPRGDNAVLMVFAGDHGLTEEGVS
QYPSAVTVAMVMTYLAGRACANAFAAATHVDVRVIDAGVAADLPAHPDLIDAKVRKGTGNAACEPAMTIAQAALALARGS
ELAIAEIKAGADIIALGEMGIGNTASSSLLLHRLAPAPLDHCIGVGAGQDAPGLAKKRAAIEKAAARSDATAPFEVLCEF
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALLAVRLAPDARGYCVFAHRSAERGHSLALEALQASPLLDLDMRLGEG
TGAILAVPLVRAASRLLTDVADLSDVLAGKL

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=336, Percent_Identity=34.5238095238095, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35897; Mature: 35897

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDTLVAWQAPPIMPVDRALRAALRARVDGKAKPPGSLGRIEHLAVELGAMRHPAPPRG
CCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DNAVLMVFAGDHGLTEEGVSQYPSAVTVAMVMTYLAGRACANAFAAATHVDVRVIDAGVA
CCEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
ADLPAHPDLIDAKVRKGTGNAACEPAMTIAQAALALARGSELAIAEIKAGADIIALGEMG
CCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCC
IGNTASSSLLLHRLAPAPLDHCIGVGAGQDAPGLAKKRAAIEKAAARSDATAPFEVLCEF
CCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHC
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALLAVRLAPDARGYCVFAHRSAERGHSL
CCCHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
ALEALQASPLLDLDMRLGEGTGAILAVPLVRAASRLLTDVADLSDVLAGKL
HHHHHHCCCCEEEHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTDTLVAWQAPPIMPVDRALRAALRARVDGKAKPPGSLGRIEHLAVELGAMRHPAPPRG
CCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DNAVLMVFAGDHGLTEEGVSQYPSAVTVAMVMTYLAGRACANAFAAATHVDVRVIDAGVA
CCEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
ADLPAHPDLIDAKVRKGTGNAACEPAMTIAQAALALARGSELAIAEIKAGADIIALGEMG
CCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCC
IGNTASSSLLLHRLAPAPLDHCIGVGAGQDAPGLAKKRAAIEKAAARSDATAPFEVLCEF
CCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHC
GGLEIAMMAGAVLGAASQRRPVIIDGFIATAAALLAVRLAPDARGYCVFAHRSAERGHSL
CCCHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
ALEALQASPLLDLDMRLGEGTGAILAVPLVRAASRLLTDVADLSDVLAGKL
HHHHHHCCCCEEEHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA