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The map label for this gene is cobO [H]

Identifier: 86747863

GI number: 86747863

Start: 827330

End: 827956

Strand: Reverse

Name: cobO [H]

Synonym: RPB_0737

Alternate gene names: 86747863

Gene position: 827956-827330 (Counterclockwise)

Preceding gene: 86747864

Following gene: 86747862

Centisome position: 15.53

GC content: 65.07

Gene sequence:

>627_bases
ATGACCGACGCCGCGCCCGATCGCGACGACAACGCCCGCCACGCCGAGAAGGCGAAGAAGCGCAAGGCCGCTCACGACAA
GAAGCTCGAAGGCATGGTCGCCGACAAGGGGCTGCTGATCGTCCACACCGGCACCGGCAAGGGCAAGACCTCGGCCGCAC
TCGGCATGGTGTTCCGCCACATCGGCCACGGCATGCCGGTCGGCGTGGTGCATTTCACCAAATCGGAGAAGTGGGACACC
GGCGAGGCCAAGCTGCTGGCGCAGTTTCCCGATCTGGTGACGCTGCACATCATGGGCGAAGGCTTCACCTGGGAGACCCA
GGACCGCGAACGCGACGTCGCCGCCGCCCGCGCCGGCTGGGAGCGCGCCAAGGAGCTGATCCGTGACGACCGCCATCGCA
TGGTGCTGCTGGACGAACTCAACATCGTGCTGCGCTACGACTATCTGCCGATCTCCGAAGTGATCGCCTTCCTGCTCGAC
GAGAAGCCCGCCGACAAACACGTCGTCATCACCGGCCGCAACGCCAACCCGGCGCTGATCGAGATCGCCGACCTGGTGAC
CGAGATGACGCTGGTGAAACATCCTTTCCGCAGCGGCGTGAAAGCGCAGAAGGGCGTGGAGTTTTGA

Upstream 100 bases:

>100_bases
CCGAACGCTTCGCCGAGGCGCTGCGGCGCGGGCTGTGGACGCCGCGCAGCAACCACGCCGCCGACCTGCTCGCCGAGTTG
TTACTTCAGAAGGAATCCGC

Downstream 100 bases:

>100_bases
GCGCTCACGTGGCACCGCGCGTCTCTTACCCTCCCCCTTGCGGGGAGGGTGGACGGCCGCAGGCCGGCCGGGTGGGGGTA
CCCCGAGCACCGTGCTCGCG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTDAAPDRDDNARHAEKAKKRKAAHDKKLEGMVADKGLLIVHTGTGKGKTSAALGMVFRHIGHGMPVGVVHFTKSEKWDT
GEAKLLAQFPDLVTLHIMGEGFTWETQDRERDVAAARAGWERAKELIRDDRHRMVLLDELNIVLRYDYLPISEVIAFLLD
EKPADKHVVITGRNANPALIEIADLVTEMTLVKHPFRSGVKAQKGVEF

Sequences:

>Translated_208_residues
MTDAAPDRDDNARHAEKAKKRKAAHDKKLEGMVADKGLLIVHTGTGKGKTSAALGMVFRHIGHGMPVGVVHFTKSEKWDT
GEAKLLAQFPDLVTLHIMGEGFTWETQDRERDVAAARAGWERAKELIRDDRHRMVLLDELNIVLRYDYLPISEVIAFLLD
EKPADKHVVITGRNANPALIEIADLVTEMTLVKHPFRSGVKAQKGVEF
>Mature_207_residues
TDAAPDRDDNARHAEKAKKRKAAHDKKLEGMVADKGLLIVHTGTGKGKTSAALGMVFRHIGHGMPVGVVHFTKSEKWDTG
EAKLLAQFPDLVTLHIMGEGFTWETQDRERDVAAARAGWERAKELIRDDRHRMVLLDELNIVLRYDYLPISEVIAFLLDE
KPADKHVVITGRNANPALIEIADLVTEMTLVKHPFRSGVKAQKGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=44.3877551020408, Blast_Score=169, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23207; Mature: 23076

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAPDRDDNARHAEKAKKRKAAHDKKLEGMVADKGLLIVHTGTGKGKTSAALGMVFRH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCEEEEECCCCCCCHHHHHHHHHHH
IGHGMPVGVVHFTKSEKWDTGEAKLLAQFPDLVTLHIMGEGFTWETQDRERDVAAARAGW
HCCCCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCCCEECCCCHHHHHHHHHHHH
ERAKELIRDDRHRMVLLDELNIVLRYDYLPISEVIAFLLDEKPADKHVVITGRNANPALI
HHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
EIADLVTEMTLVKHPFRSGVKAQKGVEF
HHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDAAPDRDDNARHAEKAKKRKAAHDKKLEGMVADKGLLIVHTGTGKGKTSAALGMVFRH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCEEEEECCCCCCCHHHHHHHHHHH
IGHGMPVGVVHFTKSEKWDTGEAKLLAQFPDLVTLHIMGEGFTWETQDRERDVAAARAGW
HCCCCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCCCEECCCCHHHHHHHHHHHH
ERAKELIRDDRHRMVLLDELNIVLRYDYLPISEVIAFLLDEKPADKHVVITGRNANPALI
HHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
EIADLVTEMTLVKHPFRSGVKAQKGVEF
HHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]