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The map label for this gene is gcp [H]

Identifier: 86747441

GI number: 86747441

Start: 358534

End: 359601

Strand: Direct

Name: gcp [H]

Synonym: RPB_0315

Alternate gene names: 86747441

Gene position: 358534-359601 (Clockwise)

Preceding gene: 86747435

Following gene: 86747442

Centisome position: 6.72

GC content: 70.97

Gene sequence:

>1068_bases
GTGCTTGGAATCGAGACCACCTGCGATGAAACCGCAGCCGCGGTGGTCGAGCGCCGCGCCGATGGCAGCGGCCGGATTCT
CTCCAATATCGTACGCTCGCAGACCGACGAACACGCGCCGTTCGGCGGCGTGGTCCCGGAAATCGCCGCGCGCGCCCATG
TCGATCTGCTCGACGGCATCGTCGCGCGGGCGATGCGGGAGGCGGGAACCGGCTTCCCGGAATTGTCGGGCGTCGCGGCG
GCGGCAGGGCCGGGGCTGATCGGCGGCGTCATCGTCGGGCTGACCACCGCCAAGGCGATCGCGCTGGTGCACAACACGCC
GCTGATCGCGGTCAATCATCTGGAAGCGCACGCGCTGACGCCGCGGCTGACGGATGCGACCGAGTTTCCCTATTGCCTGT
TTCTCGCCTCCGGCGGCCACACCCAGATCGTCGCGGTGCGCGGCGTCGGCGACTATGTCCGGCTCGGCACCACGGTCGAC
GACGCGATCGGCGAGGCGTTCGACAAGATCGCCAAGATGCTCGGCCTGCCCTATCCGGGCGGGCCGCAGGTCGAGCGCGC
CGCAGCCTCCGGCGATGCGGTGCGGTTCGCGTTTCCGCGGCCGATGCTGGGGCGGCCCGACGCCAATTTCTCATTGTCCG
GTCTCAAGACAGCGGTGCGCAACGAGGCCAGCCGGCTGACGCCGCTGGAGCCACAGGACATCAATGATCTGTGCGCCGGC
TTCCAGGCCGCGGTGCTGGACTCGATGGCCGACCGGCTGACCTCCGGACTGCGGCTGTTCCGCGAGCGCTTCGGCGCACC
GAAGGCGCTGGTCGCGGCCGGCGGCGTCGCCGCCAATCAGGCGATCCGCCGCGCCTTGCGCGAGGTCGCCGCCAAGGCCC
AGACCACGCTGATCGTGCCGCCGCCGGCGCTGTGCACCGACAACGGCGCGATGATCGCCTGGGCCGGCGCCGAGCGCCTG
GCGCTCGGCCTCACCGACAGCATGGACGCCGCCCCCCGCGCCCGCTGGCTGCTCGACGCCAACGCGACGGCGCCGGGCAA
ATTCGCCAATACCCGCGCGGGATTTTAA

Upstream 100 bases:

>100_bases
GATTGCATTCCGAGACCCCGCAATGCTACGCGAGGCAAGGAGAACGCCGGTTCGGCGGCAAACGCAAGGGCTCAATTTGA
CTAGTGAACAGACCTTGCTG

Downstream 100 bases:

>100_bases
CGGAGTCACCAAGTGGTCCTTCCACGCGCCGCAGCGCCTCCTCTCCTCTCCCCGCGCGCGGGGAGAGGTCGACGCGCATC
GCCAGATGCGCGGCGGGTGA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLGIETTCDETAAAVVERRADGSGRILSNIVRSQTDEHAPFGGVVPEIAARAHVDLLDGIVARAMREAGTGFPELSGVAA
AAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALTPRLTDATEFPYCLFLASGGHTQIVAVRGVGDYVRLGTTVD
DAIGEAFDKIAKMLGLPYPGGPQVERAAASGDAVRFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAG
FQAAVLDSMADRLTSGLRLFRERFGAPKALVAAGGVAANQAIRRALREVAAKAQTTLIVPPPALCTDNGAMIAWAGAERL
ALGLTDSMDAAPRARWLLDANATAPGKFANTRAGF

Sequences:

>Translated_355_residues
MLGIETTCDETAAAVVERRADGSGRILSNIVRSQTDEHAPFGGVVPEIAARAHVDLLDGIVARAMREAGTGFPELSGVAA
AAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALTPRLTDATEFPYCLFLASGGHTQIVAVRGVGDYVRLGTTVD
DAIGEAFDKIAKMLGLPYPGGPQVERAAASGDAVRFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAG
FQAAVLDSMADRLTSGLRLFRERFGAPKALVAAGGVAANQAIRRALREVAAKAQTTLIVPPPALCTDNGAMIAWAGAERL
ALGLTDSMDAAPRARWLLDANATAPGKFANTRAGF
>Mature_355_residues
MLGIETTCDETAAAVVERRADGSGRILSNIVRSQTDEHAPFGGVVPEIAARAHVDLLDGIVARAMREAGTGFPELSGVAA
AAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALTPRLTDATEFPYCLFLASGGHTQIVAVRGVGDYVRLGTTVD
DAIGEAFDKIAKMLGLPYPGGPQVERAAASGDAVRFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAG
FQAAVLDSMADRLTSGLRLFRERFGAPKALVAAGGVAANQAIRRALREVAAKAQTTLIVPPPALCTDNGAMIAWAGAERL
ALGLTDSMDAAPRARWLLDANATAPGKFANTRAGF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=37.2434017595308, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI8923380, Length=334, Percent_Identity=27.2455089820359, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=43.952802359882, Blast_Score=265, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=33.8368580060423, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71995670, Length=334, Percent_Identity=29.3413173652695, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=29.7814207650273, Blast_Score=155, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6322891, Length=328, Percent_Identity=24.0853658536585, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=35.672514619883, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI21357207, Length=334, Percent_Identity=26.3473053892216, Blast_Score=114, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36843; Mature: 36843

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIETTCDETAAAVVERRADGSGRILSNIVRSQTDEHAPFGGVVPEIAARAHVDLLDGI
CCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VARAMREAGTGFPELSGVAAAAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALT
HHHHHHHHCCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHCC
PRLTDATEFPYCLFLASGGHTQIVAVRGVGDYVRLGTTVDDAIGEAFDKIAKMLGLPYPG
CCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GPQVERAAASGDAVRFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAG
CCCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FQAAVLDSMADRLTSGLRLFRERFGAPKALVAAGGVAANQAIRRALREVAAKAQTTLIVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEC
PPALCTDNGAMIAWAGAERLALGLTDSMDAAPRARWLLDANATAPGKFANTRAGF
CCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLGIETTCDETAAAVVERRADGSGRILSNIVRSQTDEHAPFGGVVPEIAARAHVDLLDGI
CCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VARAMREAGTGFPELSGVAAAAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALT
HHHHHHHHCCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHCC
PRLTDATEFPYCLFLASGGHTQIVAVRGVGDYVRLGTTVDDAIGEAFDKIAKMLGLPYPG
CCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GPQVERAAASGDAVRFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAG
CCCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FQAAVLDSMADRLTSGLRLFRERFGAPKALVAAGGVAANQAIRRALREVAAKAQTTLIVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEC
PPALCTDNGAMIAWAGAERLALGLTDSMDAAPRARWLLDANATAPGKFANTRAGF
CCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA