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The map label for this gene is gpsA

Identifier: 86747442

GI number: 86747442

Start: 359862

End: 360851

Strand: Direct

Name: gpsA

Synonym: RPB_0316

Alternate gene names: 86747442

Gene position: 359862-360851 (Clockwise)

Preceding gene: 86747441

Following gene: 86747443

Centisome position: 6.75

GC content: 70.4

Gene sequence:

>990_bases
ATGAGTTCATTCGACACGATCGCGGTGCTCGGCGGCGGCGCCTGGGGGACGGCGCTGGCGCTGACGGCGGCACGCGCCGG
GCGCAGCGTGACGCTGTGGGAGCACGATGCCGGCAATGCGCAGCATCTGATCGAGGCGCGCGAAAGCCGGTTTCTGCCGG
GCGTGCGGCTCGACGATTCGATCAAGGTGACGCAGGATCTCGCCGAAGCCGCACGCGCGCAGGCGCTGCTGCTGGTGGTG
CCGGCGCAGGTGTTGCGGTCGGTGGCGACCTCACTGCAGCCGCTGATCGCGGCGCGCACGCCGCTGATCGCCTGCGCCAA
GGGCATCGAGCACGGCACCCACCGCTTCATGACCGAGATCATCGCCGAATGCGCGCCGAATGCGGTGCCGGCGATCCTGT
CCGGCCCGAGCTTCGCCGCCGACGTCGCCCGCGGGCTGCCGACCGCGGTGACGATCGCCGCCACCGACGCCGATGTCGCG
CAGGCGCTGGCGCAGGCGATGAATTCCGGCTCGTTCCGCCCCTATCACTCCACCGACGTGCGCGGTGTCGAACTCGGCGG
CGCCACCAAGAACGTGATGGCGATCGCGGCCGGCATCGTCGCCGGCCGCCAGCTCGGCGCCTCGGCGCTGGCGGCGATGA
CGACGCGCGGCTTCGTCGAACTGGTCCGGTTCGGCAAAGCCTACGGCGCCCGGATCGAGACCATGCACGGTCTGTCCGGA
TTGGGCGATCTGACGATGTGCTGCTCGACGCCGCAATCGCGCAATTTTTCGTTCGGCATGGCGCTCGGCCGCGGCGAGAG
CATCGACACCGCCGCGCACGGCAAGCTCGCGGAAGGCTACTACACCGCGCCGGTGCTGCTGGAGATGGCGCAGGCGAAAG
GCGTCGAGATGCCGATCTCGACCGCGGTCGCGGCGATCCTCGACGGCCGGCTCGGCGTCGATGCGGCGATCGAGGGCCTG
CTGACGCGGCCATTGAAGGCGGAGGAATAG

Upstream 100 bases:

>100_bases
CCCGCAAGAGCGGGGCGAGGGAGCAGGCCGCATACGCGGCGGCTCTGCGTTCACTCACTTCGGCTGTTGCTGATTGCCAT
CGCTTCAACGAGGCCATCCG

Downstream 100 bases:

>100_bases
GATTTGGCTTACTGGCTGGTGAAATCGGAGCCCTCGGTGTGGTCGTGGGACCAGCAGGTCGCCAAGGGCGCCAAGGGCGA
AGCCTGGACCGGCGTGCGCA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSSFDTIAVLGGGAWGTALALTAARAGRSVTLWEHDAGNAQHLIEARESRFLPGVRLDDSIKVTQDLAEAARAQALLLVV
PAQVLRSVATSLQPLIAARTPLIACAKGIEHGTHRFMTEIIAECAPNAVPAILSGPSFAADVARGLPTAVTIAATDADVA
QALAQAMNSGSFRPYHSTDVRGVELGGATKNVMAIAAGIVAGRQLGASALAAMTTRGFVELVRFGKAYGARIETMHGLSG
LGDLTMCCSTPQSRNFSFGMALGRGESIDTAAHGKLAEGYYTAPVLLEMAQAKGVEMPISTAVAAILDGRLGVDAAIEGL
LTRPLKAEE

Sequences:

>Translated_329_residues
MSSFDTIAVLGGGAWGTALALTAARAGRSVTLWEHDAGNAQHLIEARESRFLPGVRLDDSIKVTQDLAEAARAQALLLVV
PAQVLRSVATSLQPLIAARTPLIACAKGIEHGTHRFMTEIIAECAPNAVPAILSGPSFAADVARGLPTAVTIAATDADVA
QALAQAMNSGSFRPYHSTDVRGVELGGATKNVMAIAAGIVAGRQLGASALAAMTTRGFVELVRFGKAYGARIETMHGLSG
LGDLTMCCSTPQSRNFSFGMALGRGESIDTAAHGKLAEGYYTAPVLLEMAQAKGVEMPISTAVAAILDGRLGVDAAIEGL
LTRPLKAEE
>Mature_328_residues
SSFDTIAVLGGGAWGTALALTAARAGRSVTLWEHDAGNAQHLIEARESRFLPGVRLDDSIKVTQDLAEAARAQALLLVVP
AQVLRSVATSLQPLIAARTPLIACAKGIEHGTHRFMTEIIAECAPNAVPAILSGPSFAADVARGLPTAVTIAATDADVAQ
ALAQAMNSGSFRPYHSTDVRGVELGGATKNVMAIAAGIVAGRQLGASALAAMTTRGFVELVRFGKAYGARIETMHGLSGL
GDLTMCCSTPQSRNFSFGMALGRGESIDTAAHGKLAEGYYTAPVLLEMAQAKGVEMPISTAVAAILDGRLGVDAAIEGLL
TRPLKAEE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=331, Percent_Identity=28.3987915407855, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI24307999, Length=344, Percent_Identity=23.8372093023256, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=41.2121212121212, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI32564399, Length=345, Percent_Identity=26.9565217391304, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564403, Length=354, Percent_Identity=26.5536723163842, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=354, Percent_Identity=26.5536723163842, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17507425, Length=352, Percent_Identity=26.1363636363636, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=340, Percent_Identity=27.0588235294118, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=343, Percent_Identity=25.9475218658892, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=28.1159420289855, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17136202, Length=345, Percent_Identity=28.1159420289855, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17136204, Length=345, Percent_Identity=28.1159420289855, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI22026922, Length=342, Percent_Identity=24.5614035087719, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI45551945, Length=343, Percent_Identity=24.7813411078717, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=282, Percent_Identity=25.886524822695, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648969, Length=288, Percent_Identity=25.6944444444444, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_RHOP2 (Q2J3D3)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_483938.1
- ProteinModelPortal:   Q2J3D3
- SMR:   Q2J3D3
- STRING:   Q2J3D3
- GeneID:   3908697
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0316
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- ProtClustDB:   PRK00094
- BioCyc:   RPAL316058:RPB_0316-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 33958; Mature: 33827

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 190-190 BINDING 107-107 BINDING 107-107 BINDING 139-139 BINDING 254-254 BINDING 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFDTIAVLGGGAWGTALALTAARAGRSVTLWEHDAGNAQHLIEARESRFLPGVRLDDS
CCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
IKVTQDLAEAARAQALLLVVPAQVLRSVATSLQPLIAARTPLIACAKGIEHGTHRFMTEI
HHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IAECAPNAVPAILSGPSFAADVARGLPTAVTIAATDADVAQALAQAMNSGSFRPYHSTDV
HHHHCCCCCCHHHCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCC
RGVELGGATKNVMAIAAGIVAGRQLGASALAAMTTRGFVELVRFGKAYGARIETMHGLSG
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
LGDLTMCCSTPQSRNFSFGMALGRGESIDTAAHGKLAEGYYTAPVLLEMAQAKGVEMPIS
CCCHHHHCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHH
TAVAAILDGRLGVDAAIEGLLTRPLKAEE
HHHHHHHCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSFDTIAVLGGGAWGTALALTAARAGRSVTLWEHDAGNAQHLIEARESRFLPGVRLDDS
CCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
IKVTQDLAEAARAQALLLVVPAQVLRSVATSLQPLIAARTPLIACAKGIEHGTHRFMTEI
HHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IAECAPNAVPAILSGPSFAADVARGLPTAVTIAATDADVAQALAQAMNSGSFRPYHSTDV
HHHHCCCCCCHHHCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCC
RGVELGGATKNVMAIAAGIVAGRQLGASALAAMTTRGFVELVRFGKAYGARIETMHGLSG
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
LGDLTMCCSTPQSRNFSFGMALGRGESIDTAAHGKLAEGYYTAPVLLEMAQAKGVEMPIS
CCCHHHHCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHH
TAVAAILDGRLGVDAAIEGLLTRPLKAEE
HHHHHHHCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA