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The map label for this gene is cmpB [H]

Identifier: 86747435

GI number: 86747435

Start: 350173

End: 351006

Strand: Direct

Name: cmpB [H]

Synonym: RPB_0309

Alternate gene names: 86747435

Gene position: 350173-351006 (Clockwise)

Preceding gene: 86747434

Following gene: 86747441

Centisome position: 6.57

GC content: 69.42

Gene sequence:

>834_bases
GTGAGCCTCGATCTGACGATCGACGACGCCCCGGCACCGGCGGCGGCGGCGCGAAACGCCGCCTTCGCCGGCCGGCTGCG
CAGCTCCGGCCATATCGCGCTCGGCATCGCGGTGCTGCTCGGCGTGTGGTGGATCGGCGGCTTCATCGTCGCCTCCGATC
CGCGCACCGCGAATTTCGCCGACTTCGCCCCACAGCCGACCTTCGAGCGGCTGTGGCAGATGCTGATCAGCGGCGAGGCG
GCCAAGATGGCGTGGCCGAGTCTCGGCCGGATCGCCGGCGGGCTCGCCTGGGCGATCGCGCTCGGCGTGCCGCTCGGCAT
TCTGGTCGGCCGTTTCCGCGGCATGCGCGAGGCGAGCTCGGTGCCGTTCCAGTTCCTGCGGATGATTTCGCCGCTGGCCT
GGATGCCGATCGCCGTGATGGCGTTTGCGAGCTGGAACGCCGCGATCGTGTTCCTGATCGGCGTGGCGGCGATCTGGCCG
ATCCTGTTCTCGACCGCGCACGGCTTCCGTCGGATCGACCCGGCGTGGTTCAAGGTCGCGCGCAATCTCGGCGCCCGGCC
GTGGCACATGCTGTTCACCATCATCGTGCCGGCGATCATGCAGGATTCGCTGGCCGGCATCCGGCTCGCCGTCGGCGTCG
CCTGGATCGTGCTGGTGCCGGCCGAATTCCTCGGCGTCACTTCCGGCCTCGGCTATGCCATCAACGACGCCCGCGACACG
CTGGAATACGACCGCCTCGCCGCCACCGTGGTGATCATCGGCCTGATCGGCTTCGCCCTCGACTTCCTCTGCGAACGCGC
CGTCAAACGCGCCAGCTGGGCAAGGGAGGAGTGA

Upstream 100 bases:

>100_bases
ATCACTTCGTCAAGCAGGCGATGACGAAGTACCCGGACTGGAAGACATCGCCGAGCGTCAATCCCGACGATCCGTTCGCC
CGGACCGAGGTGCTGTCGCT

Downstream 100 bases:

>100_bases
GCGGGAGGAGTGATCCCAACGGCGCCGCCGCATCGAGACGTTATGCCCGCGCGCGTCGCGGGCATTTTCGTCCAGAGAAT
TGGCGTGGGGGGTCGAAGCG

Product: binding-protein dependent transport system inner membrane protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSLDLTIDDAPAPAAAARNAAFAGRLRSSGHIALGIAVLLGVWWIGGFIVASDPRTANFADFAPQPTFERLWQMLISGEA
AKMAWPSLGRIAGGLAWAIALGVPLGILVGRFRGMREASSVPFQFLRMISPLAWMPIAVMAFASWNAAIVFLIGVAAIWP
ILFSTAHGFRRIDPAWFKVARNLGARPWHMLFTIIVPAIMQDSLAGIRLAVGVAWIVLVPAEFLGVTSGLGYAINDARDT
LEYDRLAATVVIIGLIGFALDFLCERAVKRASWAREE

Sequences:

>Translated_277_residues
MSLDLTIDDAPAPAAAARNAAFAGRLRSSGHIALGIAVLLGVWWIGGFIVASDPRTANFADFAPQPTFERLWQMLISGEA
AKMAWPSLGRIAGGLAWAIALGVPLGILVGRFRGMREASSVPFQFLRMISPLAWMPIAVMAFASWNAAIVFLIGVAAIWP
ILFSTAHGFRRIDPAWFKVARNLGARPWHMLFTIIVPAIMQDSLAGIRLAVGVAWIVLVPAEFLGVTSGLGYAINDARDT
LEYDRLAATVVIIGLIGFALDFLCERAVKRASWAREE
>Mature_276_residues
SLDLTIDDAPAPAAAARNAAFAGRLRSSGHIALGIAVLLGVWWIGGFIVASDPRTANFADFAPQPTFERLWQMLISGEAA
KMAWPSLGRIAGGLAWAIALGVPLGILVGRFRGMREASSVPFQFLRMISPLAWMPIAVMAFASWNAAIVFLIGVAAIWPI
LFSTAHGFRRIDPAWFKVARNLGARPWHMLFTIIVPAIMQDSLAGIRLAVGVAWIVLVPAEFLGVTSGLGYAINDARDTL
EYDRLAATVVIIGLIGFALDFLCERAVKRASWAREE

Specific function: Part of the ABC transporter complex CmpABCD involved in bicarbonate transport. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=242, Percent_Identity=30.9917355371901, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081802, Length=146, Percent_Identity=30.8219178082192, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005889 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29927; Mature: 29795

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDLTIDDAPAPAAAARNAAFAGRLRSSGHIALGIAVLLGVWWIGGFIVASDPRTANFA
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
DFAPQPTFERLWQMLISGEAAKMAWPSLGRIAGGLAWAIALGVPLGILVGRFRGMREASS
CCCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHC
VPFQFLRMISPLAWMPIAVMAFASWNAAIVFLIGVAAIWPILFSTAHGFRRIDPAWFKVA
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHH
RNLGARPWHMLFTIIVPAIMQDSLAGIRLAVGVAWIVLVPAEFLGVTSGLGYAINDARDT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
LEYDRLAATVVIIGLIGFALDFLCERAVKRASWAREE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLDLTIDDAPAPAAAARNAAFAGRLRSSGHIALGIAVLLGVWWIGGFIVASDPRTANFA
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
DFAPQPTFERLWQMLISGEAAKMAWPSLGRIAGGLAWAIALGVPLGILVGRFRGMREASS
CCCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHC
VPFQFLRMISPLAWMPIAVMAFASWNAAIVFLIGVAAIWPILFSTAHGFRRIDPAWFKVA
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHH
RNLGARPWHMLFTIIVPAIMQDSLAGIRLAVGVAWIVLVPAEFLGVTSGLGYAINDARDT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
LEYDRLAATVVIIGLIGFALDFLCERAVKRASWAREE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA