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The map label for this gene is sdhB [H]

Identifier: 86609940

GI number: 86609940

Start: 2599598

End: 2600629

Strand: Direct

Name: sdhB [H]

Synonym: CYB_2507

Alternate gene names: 86609940

Gene position: 2599598-2600629 (Clockwise)

Preceding gene: 86609938

Following gene: 86609944

Centisome position: 85.33

GC content: 61.92

Gene sequence:

>1032_bases
TTGCGAGTAGAATTTCAGATTTTCCGACAGTTGCCGCCGGAGCCGCCCCGCTGGCAGTCCTTCTGGCTGGAGACATCCCC
TGGCGCCACCATTCTCGATTGCCTCAACCAGATCAAGTGGGAGCAGGATGGCAGCTTGGCCTTCCGCAAAAACTGCCGCA
ACACCATCTGTGGCAGTTGCGCCATGCGCATCAACGGTAGGGCAGCCTTGGCTTGTGGCCGACATGTGGGCGAAGAGCTG
GATCCCCGCAGCCCCCAGCCGCAGCCTATTCGCATCGGCCCTCTGGGAAACCTGCCCGTTCTGCGGGATCTGGTGGTGGA
TATGCAGCCCTTCTGGAACGATCTCAGCCGGGTGGATCCCTTTGTCAGCACGGCGGGGCGACGCATCCCGGAGCGAGAGT
TTTTACAGCTGCCTGCCGAACGGGAGCATCTCAACGCTGCCGGTGGCTGTATTCTCTGCGGAGCCTGCTATTCCGATTGC
AATGCCAAAGAGGTGAACCCAGAGTTTGTCGGCCCCCATGCTCTGGCCAGAGCCAACCGCCTCGTCCAAGACAGCCGCGA
CAGCCAACGGGAACAACGCCTGCAGGCTCTGGATAGCTTGGCTGGTGTCTGGGGCTGTACCCGCTGCTGGAACTGCAACA
GCGTCTGCCCGATGGGCGTGGCACCTCTGGATCAAATCACCGAACTCAAACAGGGGATCCTCTCCCGCCCTGTAGACAAG
ACCGCTGCTCTGCCCACCGACCGTTCCCGCCAGCACGCTGTTCGCGCTATTCGGACGGAGTCCTTGCCCATAGCCATCCG
CCACCGCAAGACTCTGGTGCAACTGGTGCGCTCCGGTGGTTGGATAGATGAGCGCCGCTTTGCCCTGCAGGTGGTGGGCC
GGGATCCCAAAGGGCTGCTCAGCTTGGTGCCTCTGGGGCTGCGCCTGTTGGTCAGGGGCAAATTTCCCTTTCGCTTCCAG
CCCTCTTCAGGGGCGGCGACGGTACGGCGGCTTATCGACACAGTTAGGCAGGAAGGAAGGGATCCCCTCTAG

Upstream 100 bases:

>100_bases
GCCGCGCGTTGTAGCCACTTCTGCTGTCCCGTTAGCGTTGCGGAGCAATAGGGAGAGAGCTAGGATGGGATCCCCTTTCC
CTTCAGCGGTGCAGAGCACT

Downstream 100 bases:

>100_bases
GCTCCAGTTTTGAGGTTGTCTTGGCCGGAAATCAATCTGGCACTCAAAATCCGATCCCCCACTTTGATGTGGCGCAGCAC
CTCCGTTCCCTCGGTAACGT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRVEFQIFRQLPPEPPRWQSFWLETSPGATILDCLNQIKWEQDGSLAFRKNCRNTICGSCAMRINGRAALACGRHVGEEL
DPRSPQPQPIRIGPLGNLPVLRDLVVDMQPFWNDLSRVDPFVSTAGRRIPEREFLQLPAEREHLNAAGGCILCGACYSDC
NAKEVNPEFVGPHALARANRLVQDSRDSQREQRLQALDSLAGVWGCTRCWNCNSVCPMGVAPLDQITELKQGILSRPVDK
TAALPTDRSRQHAVRAIRTESLPIAIRHRKTLVQLVRSGGWIDERRFALQVVGRDPKGLLSLVPLGLRLLVRGKFPFRFQ
PSSGAATVRRLIDTVRQEGRDPL

Sequences:

>Translated_343_residues
MRVEFQIFRQLPPEPPRWQSFWLETSPGATILDCLNQIKWEQDGSLAFRKNCRNTICGSCAMRINGRAALACGRHVGEEL
DPRSPQPQPIRIGPLGNLPVLRDLVVDMQPFWNDLSRVDPFVSTAGRRIPEREFLQLPAEREHLNAAGGCILCGACYSDC
NAKEVNPEFVGPHALARANRLVQDSRDSQREQRLQALDSLAGVWGCTRCWNCNSVCPMGVAPLDQITELKQGILSRPVDK
TAALPTDRSRQHAVRAIRTESLPIAIRHRKTLVQLVRSGGWIDERRFALQVVGRDPKGLLSLVPLGLRLLVRGKFPFRFQ
PSSGAATVRRLIDTVRQEGRDPL
>Mature_343_residues
MRVEFQIFRQLPPEPPRWQSFWLETSPGATILDCLNQIKWEQDGSLAFRKNCRNTICGSCAMRINGRAALACGRHVGEEL
DPRSPQPQPIRIGPLGNLPVLRDLVVDMQPFWNDLSRVDPFVSTAGRRIPEREFLQLPAEREHLNAAGGCILCGACYSDC
NAKEVNPEFVGPHALARANRLVQDSRDSQREQRLQALDSLAGVWGCTRCWNCNSVCPMGVAPLDQITELKQGILSRPVDK
TAALPTDRSRQHAVRAIRTESLPIAIRHRKTLVQLVRSGGWIDERRFALQVVGRDPKGLLSLVPLGLRLLVRGKFPFRFQ
PSSGAATVRRLIDTVRQEGRDPL

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=245, Percent_Identity=33.469387755102, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1786943, Length=244, Percent_Identity=40.5737704918033, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1790596, Length=231, Percent_Identity=34.6320346320346, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17533915, Length=252, Percent_Identity=33.7301587301587, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322987, Length=234, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24643156, Length=247, Percent_Identity=35.2226720647773, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17137106, Length=254, Percent_Identity=34.6456692913386, Blast_Score=138, Evalue=7e-33,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 38429; Mature: 38429

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEFQIFRQLPPEPPRWQSFWLETSPGATILDCLNQIKWEQDGSLAFRKNCRNTICGSC
CCCHHHHHHCCCCCCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AMRINGRAALACGRHVGEELDPRSPQPQPIRIGPLGNLPVLRDLVVDMQPFWNDLSRVDP
HEEECCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
FVSTAGRRIPEREFLQLPAEREHLNAAGGCILCGACYSDCNAKEVNPEFVGPHALARANR
HHHHHCCCCCHHHHHHCCCHHHHHCCCCCEEEEECHHCCCCCCCCCCCCCCHHHHHHHHH
LVQDSRDSQREQRLQALDSLAGVWGCTRCWNCNSVCPMGVAPLDQITELKQGILSRPVDK
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
TAALPTDRSRQHAVRAIRTESLPIAIRHRKTLVQLVRSGGWIDERRFALQVVGRDPKGLL
HHCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHEEEEECCCHHHHH
SLVPLGLRLLVRGKFPFRFQPSSGAATVRRLIDTVRQEGRDPL
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRVEFQIFRQLPPEPPRWQSFWLETSPGATILDCLNQIKWEQDGSLAFRKNCRNTICGSC
CCCHHHHHHCCCCCCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AMRINGRAALACGRHVGEELDPRSPQPQPIRIGPLGNLPVLRDLVVDMQPFWNDLSRVDP
HEEECCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
FVSTAGRRIPEREFLQLPAEREHLNAAGGCILCGACYSDCNAKEVNPEFVGPHALARANR
HHHHHCCCCCHHHHHHCCCHHHHHCCCCCEEEEECHHCCCCCCCCCCCCCCHHHHHHHHH
LVQDSRDSQREQRLQALDSLAGVWGCTRCWNCNSVCPMGVAPLDQITELKQGILSRPVDK
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
TAALPTDRSRQHAVRAIRTESLPIAIRHRKTLVQLVRSGGWIDERRFALQVVGRDPKGLL
HHCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHEEEEECCCHHHHH
SLVPLGLRLLVRGKFPFRFQPSSGAATVRRLIDTVRQEGRDPL
HHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]