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The map label for this gene is 86609678

Identifier: 86609678

GI number: 86609678

Start: 2340849

End: 2342864

Strand: Direct

Name: 86609678

Synonym: CYB_2234

Alternate gene names: NA

Gene position: 2340849-2342864 (Clockwise)

Preceding gene: 86609677

Following gene: 86609679

Centisome position: 76.83

GC content: 63.94

Gene sequence:

>2016_bases
TTGGCCCGCCTGGGGATCGATGTGGGGGGCACCTTTACTGATCTGGTGCTCTTGCAGGATGGCCAGATGCAGACGGCGAA
GGTGCTGTCTACCCCCAGCCCTGAGGAGGGGGTCTTTGCGGCGCTGGACAAGCTGGGGGTGCTCTGGGTTGACCTCTTCT
GTCATGGCATGACGGTAGCCACCAACGCGCTGCTGGAGCGCAAGGGATCCCCCACCCTGTTTTTGACCACGGCGGGCTTT
CGGGATGTGCTGGCCATTGCCCGTCAAAACCGCCCCTCTCTGTATGACCTGACACAGCCCAAGCCGGAGCCGGTGGTGCC
CCGCCACCATTGCCTGGAGGTGAAGGAGCGCTGCAGCGTGGGTGGAGTGTTGGAGCCGCTCACCGATGCCGAAATCCGGC
GGGTGGTGCAGGAGGTGGGGGAACGGGTGCAGCGGGATGGGATCCGCGCTATTGGGGTGGGGTTTTTGTTTTCTTTTCTC
TACCCGGAGCACGAACAGCGGCTGGGAATGGCCTTGCGACAGGCTTTCCCGGAGCTACACCTTTCCCTGTCTTGCGAGGT
GGCGCCGGAGTTCCGAGAATACGAGCGCTTCAGCACCACCGCCATCGATGCCTACCTCAGCCCGGCATTGGCGGGCTACC
TGCACCGCTTGGCCCAAGGATGTCGGGAGCGAGGGATCCCCCAACCGTTGATCATGCAGTCTTCCGGCGGCGTGACCTCC
ATCCCTCAGGCGGCGGCCCATGCTTCGGTGGCTTTGCTCTCAGGGCCGGCAGGCGGGGTTTATGGGGCGGCCTATCTGGG
TCGCCTGAGTGGCTACCCCCACTTGCTCAGCTTCGATATGGGGGGAACCAGCACGGATGTGGCCTTGATCCAAGATGGGA
TCCCCCAGGTTACTCCCGCAGCGGTGGTGTGCGGCTTGCCCGTGCAACAGCCCCAAATTGATATCCACACCGTCAGTGCC
GGCGGCGGATCCCTGGCCCATTTGCTGCCCGGCGGTGGGCTTCAGGTGGGGCCAGAGAGTGCCGGATCCAACCCCGGGCC
GGCCTGCTACGGTCGGGGGGGAAGGGCTCCGACGGTTACCGATGCCAACCTCTGGCTGGGGTACCTGCCGGATGGCGGGC
GGCTGGGCAACTCGGTGCAGCTACGGCGGGAGCTGGCGGAACAGGCTATTGCCACGCTGGCGGATCCCTTGGGTTTGAGC
TTGCAGGAAACTGCCGTTGGCATTCGCACCTTGGCCAACGTCGCTATGTCGCGGGCCTTGCGGGTGATCAGCGTGGAGCG
GGGTTTGGATCCCGCCGATTTTGCCCTGTTGGCCTTCGGCGGAGCCGGGCCCATGCATGCCTGTGCTTTGGCAGAAGAGC
TGGGCATCCGCACGATCTTGATCCCGGCTGCCTGTGGGGTGCTCTCGGCGCTGGGAATGGCTCTGGCAGATCTGCGGCGA
GACTATCGGCGGGCCATCCTCCAACCTCTGCGGCAGCTCACGTCCGCTTCAGGGGGATCCCTGCTGGCCCAATGGGCAGA
ACCCCTGATCCGCCAGGCGAGAGCCGATCTGCAGGAGCCGGCGCTGCACTTCAGCTTGGACTTGCGCTATCGCGGCCAGT
CTTTTGAGTTGGAGATCCCGGTGCAGTTGTCAGATCCGATTCCTCATCTGGAGCAACAGTTTCACCAGGCCCACCGACAA
CGCTATGGATGGCAGGATTTGGCCCAGCCGGTGGAGGTGATTCAGTTGCGTCTACAGGCGGTGCAGGCCCTACCCACCGT
GCCTTTGACCGCACCCCCCCCCTTGCCAGGGGATCCCCTCAAGGATCGGCGAGAGGCATGGTTTGGGGGCAGGATGTGCT
CGGTGCCGGTCTACGATCGGCAGCGCATGGATGTGGGGTTTCAACTGCGCGGGCCGGCAATTGTCGAGATGCCGGAGGCA
ACGGCGGTGATCGAAGCCGGTTGGACAGGTGTCATTGACGAAGTGGGAACCCTAATCTTGAGCTGTGTTCGCGATAGCGG
GACAAAGTCCTGGTGA

Upstream 100 bases:

>100_bases
AAGAAGGCAAAAGAAATGCACGATGGAAGCCATGGTCGCATCAGCGTTGGGTAGCAACCTCGATCCGGCCAATCTGGATC
AGACGGAAGCAAGCCGCAGC

Downstream 100 bases:

>100_bases
GTCCATCCGCAAGCAGAGCGTCATGGTCATTTCGATTCAAACTAGGATACTGTGCCCACACCCAAAACGTTGCTCGCGTC
GGCGTTGCGGAGCAATAATG

Product: hydantoinase/oxoprolinase family protein

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MARLGIDVGGTFTDLVLLQDGQMQTAKVLSTPSPEEGVFAALDKLGVLWVDLFCHGMTVATNALLERKGSPTLFLTTAGF
RDVLAIARQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSVGGVLEPLTDAEIRRVVQEVGERVQRDGIRAIGVGFLFSFL
YPEHEQRLGMALRQAFPELHLSLSCEVAPEFREYERFSTTAIDAYLSPALAGYLHRLAQGCRERGIPQPLIMQSSGGVTS
IPQAAAHASVALLSGPAGGVYGAAYLGRLSGYPHLLSFDMGGTSTDVALIQDGIPQVTPAAVVCGLPVQQPQIDIHTVSA
GGGSLAHLLPGGGLQVGPESAGSNPGPACYGRGGRAPTVTDANLWLGYLPDGGRLGNSVQLRRELAEQAIATLADPLGLS
LQETAVGIRTLANVAMSRALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRTILIPAACGVLSALGMALADLRR
DYRRAILQPLRQLTSASGGSLLAQWAEPLIRQARADLQEPALHFSLDLRYRGQSFELEIPVQLSDPIPHLEQQFHQAHRQ
RYGWQDLAQPVEVIQLRLQAVQALPTVPLTAPPPLPGDPLKDRREAWFGGRMCSVPVYDRQRMDVGFQLRGPAIVEMPEA
TAVIEAGWTGVIDEVGTLILSCVRDSGTKSW

Sequences:

>Translated_671_residues
MARLGIDVGGTFTDLVLLQDGQMQTAKVLSTPSPEEGVFAALDKLGVLWVDLFCHGMTVATNALLERKGSPTLFLTTAGF
RDVLAIARQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSVGGVLEPLTDAEIRRVVQEVGERVQRDGIRAIGVGFLFSFL
YPEHEQRLGMALRQAFPELHLSLSCEVAPEFREYERFSTTAIDAYLSPALAGYLHRLAQGCRERGIPQPLIMQSSGGVTS
IPQAAAHASVALLSGPAGGVYGAAYLGRLSGYPHLLSFDMGGTSTDVALIQDGIPQVTPAAVVCGLPVQQPQIDIHTVSA
GGGSLAHLLPGGGLQVGPESAGSNPGPACYGRGGRAPTVTDANLWLGYLPDGGRLGNSVQLRRELAEQAIATLADPLGLS
LQETAVGIRTLANVAMSRALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRTILIPAACGVLSALGMALADLRR
DYRRAILQPLRQLTSASGGSLLAQWAEPLIRQARADLQEPALHFSLDLRYRGQSFELEIPVQLSDPIPHLEQQFHQAHRQ
RYGWQDLAQPVEVIQLRLQAVQALPTVPLTAPPPLPGDPLKDRREAWFGGRMCSVPVYDRQRMDVGFQLRGPAIVEMPEA
TAVIEAGWTGVIDEVGTLILSCVRDSGTKSW
>Mature_670_residues
ARLGIDVGGTFTDLVLLQDGQMQTAKVLSTPSPEEGVFAALDKLGVLWVDLFCHGMTVATNALLERKGSPTLFLTTAGFR
DVLAIARQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSVGGVLEPLTDAEIRRVVQEVGERVQRDGIRAIGVGFLFSFLY
PEHEQRLGMALRQAFPELHLSLSCEVAPEFREYERFSTTAIDAYLSPALAGYLHRLAQGCRERGIPQPLIMQSSGGVTSI
PQAAAHASVALLSGPAGGVYGAAYLGRLSGYPHLLSFDMGGTSTDVALIQDGIPQVTPAAVVCGLPVQQPQIDIHTVSAG
GGSLAHLLPGGGLQVGPESAGSNPGPACYGRGGRAPTVTDANLWLGYLPDGGRLGNSVQLRRELAEQAIATLADPLGLSL
QETAVGIRTLANVAMSRALRVISVERGLDPADFALLAFGGAGPMHACALAEELGIRTILIPAACGVLSALGMALADLRRD
YRRAILQPLRQLTSASGGSLLAQWAEPLIRQARADLQEPALHFSLDLRYRGQSFELEIPVQLSDPIPHLEQQFHQAHRQR
YGWQDLAQPVEVIQLRLQAVQALPTVPLTAPPPLPGDPLKDRREAWFGGRMCSVPVYDRQRMDVGFQLRGPAIVEMPEAT
AVIEAGWTGVIDEVGTLILSCVRDSGTKSW

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=725, Percent_Identity=33.9310344827586, Blast_Score=245, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI133901900, Length=717, Percent_Identity=28.7308228730823, Blast_Score=220, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6322634, Length=635, Percent_Identity=32.755905511811, Blast_Score=260, Evalue=4e-70,
Organism=Drosophila melanogaster, GI45550492, Length=738, Percent_Identity=32.520325203252, Blast_Score=277, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71970; Mature: 71838

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGIDVGGTFTDLVLLQDGQMQTAKVLSTPSPEEGVFAALDKLGVLWVDLFCHGMTVA
CCEECCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
TNALLERKGSPTLFLTTAGFRDVLAIARQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSV
HHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCC
GGVLEPLTDAEIRRVVQEVGERVQRDGIRAIGVGFLFSFLYPEHEQRLGMALRQAFPELH
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHE
LSLSCEVAPEFREYERFSTTAIDAYLSPALAGYLHRLAQGCRERGIPQPLIMQSSGGVTS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
IPQAAAHASVALLSGPAGGVYGAAYLGRLSGYPHLLSFDMGGTSTDVALIQDGIPQVTPA
CCHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHCCCCCCCHH
AVVCGLPVQQPQIDIHTVSAGGGSLAHLLPGGGLQVGPESAGSNPGPACYGRGGRAPTVT
HHEECCCCCCCCEEEEEEECCCCCCCEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCEE
DANLWLGYLPDGGRLGNSVQLRRELAEQAIATLADPLGLSLQETAVGIRTLANVAMSRAL
ECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RVISVERGLDPADFALLAFGGAGPMHACALAEELGIRTILIPAACGVLSALGMALADLRR
HHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHH
DYRRAILQPLRQLTSASGGSLLAQWAEPLIRQARADLQEPALHFSLDLRYRGQSFELEIP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEE
VQLSDPIPHLEQQFHQAHRQRYGWQDLAQPVEVIQLRLQAVQALPTVPLTAPPPLPGDPL
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KDRREAWFGGRMCSVPVYDRQRMDVGFQLRGPAIVEMPEATAVIEAGWTGVIDEVGTLIL
HHHHHHHHCCCEEECCCCCCHHCCCCEEECCCEEEECCCCCEEEECCCCHHHHHHHHHHH
SCVRDSGTKSW
HHHHCCCCCCC
>Mature Secondary Structure 
ARLGIDVGGTFTDLVLLQDGQMQTAKVLSTPSPEEGVFAALDKLGVLWVDLFCHGMTVA
CEECCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
TNALLERKGSPTLFLTTAGFRDVLAIARQNRPSLYDLTQPKPEPVVPRHHCLEVKERCSV
HHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCC
GGVLEPLTDAEIRRVVQEVGERVQRDGIRAIGVGFLFSFLYPEHEQRLGMALRQAFPELH
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHE
LSLSCEVAPEFREYERFSTTAIDAYLSPALAGYLHRLAQGCRERGIPQPLIMQSSGGVTS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
IPQAAAHASVALLSGPAGGVYGAAYLGRLSGYPHLLSFDMGGTSTDVALIQDGIPQVTPA
CCHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHCCCCCCCHH
AVVCGLPVQQPQIDIHTVSAGGGSLAHLLPGGGLQVGPESAGSNPGPACYGRGGRAPTVT
HHEECCCCCCCCEEEEEEECCCCCCCEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCEE
DANLWLGYLPDGGRLGNSVQLRRELAEQAIATLADPLGLSLQETAVGIRTLANVAMSRAL
ECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RVISVERGLDPADFALLAFGGAGPMHACALAEELGIRTILIPAACGVLSALGMALADLRR
HHHHHHCCCCHHHEEEEEECCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHH
DYRRAILQPLRQLTSASGGSLLAQWAEPLIRQARADLQEPALHFSLDLRYRGQSFELEIP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEE
VQLSDPIPHLEQQFHQAHRQRYGWQDLAQPVEVIQLRLQAVQALPTVPLTAPPPLPGDPL
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KDRREAWFGGRMCSVPVYDRQRMDVGFQLRGPAIVEMPEATAVIEAGWTGVIDEVGTLIL
HHHHHHHHCCCEEECCCCCCHHCCCCEEECCCEEEECCCCCEEEECCCCHHHHHHHHHHH
SCVRDSGTKSW
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]