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The map label for this gene is tcyB [H]

Identifier: 86609572

GI number: 86609572

Start: 2217975

End: 2218721

Strand: Direct

Name: tcyB [H]

Synonym: CYB_2125

Alternate gene names: 86609572

Gene position: 2217975-2218721 (Clockwise)

Preceding gene: 86609571

Following gene: 86609573

Centisome position: 72.8

GC content: 57.43

Gene sequence:

>747_bases
GTGGCCCAGGGGTTGTGGTTGGTTTTGTGGCTGCTGTTGTTGCTGTTCACCTTCAGCGGGGTACAGTTGGAGTTGGCCGG
GATCCCCATCCGTACCTTGCGTCTCAACGGCAACTTTGTGCGCGAGTGGTGGTGGTTCATCTCGCAAGGGGTGGGCACTA
CTTTTCAACTGTCCTTGGTCTCCATCCTCTGTGCCACCACCTTGGCCTTTTTGTCGGCACTGGCGGGCCTCTCCCAGATT
GCCCCTCTGAGCAGCCTCTCCGCTCTGTATGTCTCGTTGATGCGGGGCACACCTCTATTTCTGCAGTTTTTGTTCATCTA
CCAGGCTTTGCCGCAACTGGGTCTGGTGTTCGGCTCGTTCACTTCGGCAGTGCTGGCCTTGAGCCTGAACTATGGCGCCT
ACATGAGCGAGATCTTCCGGGCCGGGATCCAAGCCATTCCCATTGGGCAGCGGGAAGCTGCCTATGCCCTGGGGCTTAAG
CCCTGGCAAACCCTGTGGTGCATCATTTTGCCGCAAGCTTTCCGAATTGTCCTACCCGACATTGGCAACCAATTCATCGC
CATGCAGAAAGACACTGCCCTGGCCAGCGCCATTGCTTTGCAGGAGTTGATGGGCCGGGCTCGACAGGCGGGTTTGCCGC
GCCAACATTTTTTTGAGGCTTTGGTGGTGGCAGCGCTGTGGTACTGGCTGCTGACGTTAATCTTGTCATTTTTCCAGGGA
CGCTTGGAACGGTACCTGGCCCGCTAG

Upstream 100 bases:

>100_bases
GCATTGATCTGACGAAAAAAGCTGAGTGAGCAAAGACTCTATCCCACTGGAGCAGCCCATTTACCCACCGCCCCGGATTC
GAAAAGGGATCCCGTTCCCG

Downstream 100 bases:

>100_bases
AGGAGCCTGACTCTAATCCGGCCATTACTTTGGTGTCTGCTTGCATACGTTTGTGGTTGCCCACAAAGACCGGCTGTGCC
GTTCGCGATAGCAGGGGGCT

Product: cystine ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MAQGLWLVLWLLLLLFTFSGVQLELAGIPIRTLRLNGNFVREWWWFISQGVGTTFQLSLVSILCATTLAFLSALAGLSQI
APLSSLSALYVSLMRGTPLFLQFLFIYQALPQLGLVFGSFTSAVLALSLNYGAYMSEIFRAGIQAIPIGQREAAYALGLK
PWQTLWCIILPQAFRIVLPDIGNQFIAMQKDTALASAIALQELMGRARQAGLPRQHFFEALVVAALWYWLLTLILSFFQG
RLERYLAR

Sequences:

>Translated_248_residues
MAQGLWLVLWLLLLLFTFSGVQLELAGIPIRTLRLNGNFVREWWWFISQGVGTTFQLSLVSILCATTLAFLSALAGLSQI
APLSSLSALYVSLMRGTPLFLQFLFIYQALPQLGLVFGSFTSAVLALSLNYGAYMSEIFRAGIQAIPIGQREAAYALGLK
PWQTLWCIILPQAFRIVLPDIGNQFIAMQKDTALASAIALQELMGRARQAGLPRQHFFEALVVAALWYWLLTLILSFFQG
RLERYLAR
>Mature_247_residues
AQGLWLVLWLLLLLFTFSGVQLELAGIPIRTLRLNGNFVREWWWFISQGVGTTFQLSLVSILCATTLAFLSALAGLSQIA
PLSSLSALYVSLMRGTPLFLQFLFIYQALPQLGLVFGSFTSAVLALSLNYGAYMSEIFRAGIQAIPIGQREAAYALGLKP
WQTLWCIILPQAFRIVLPDIGNQFIAMQKDTALASAIALQELMGRARQAGLPRQHFFEALVVAALWYWLLTLILSFFQGR
LERYLAR

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=203, Percent_Identity=41.3793103448276, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787030, Length=165, Percent_Identity=38.7878787878788, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=33.6538461538462, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787087, Length=226, Percent_Identity=29.2035398230088, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786873, Length=207, Percent_Identity=32.3671497584541, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786874, Length=207, Percent_Identity=31.4009661835749, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082239, Length=201, Percent_Identity=32.8358208955224, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787086, Length=170, Percent_Identity=34.1176470588235, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788646, Length=203, Percent_Identity=29.064039408867, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI48994930, Length=80, Percent_Identity=45, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27695; Mature: 27564

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGLWLVLWLLLLLFTFSGVQLELAGIPIRTLRLNGNFVREWWWFISQGVGTTFQLSLV
CCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHH
SILCATTLAFLSALAGLSQIAPLSSLSALYVSLMRGTPLFLQFLFIYQALPQLGLVFGSF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TSAVLALSLNYGAYMSEIFRAGIQAIPIGQREAAYALGLKPWQTLWCIILPQAFRIVLPD
HHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IGNQFIAMQKDTALASAIALQELMGRARQAGLPRQHFFEALVVAALWYWLLTLILSFFQG
CCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLERYLAR
HHHHHHCC
>Mature Secondary Structure 
AQGLWLVLWLLLLLFTFSGVQLELAGIPIRTLRLNGNFVREWWWFISQGVGTTFQLSLV
CCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHH
SILCATTLAFLSALAGLSQIAPLSSLSALYVSLMRGTPLFLQFLFIYQALPQLGLVFGSF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TSAVLALSLNYGAYMSEIFRAGIQAIPIGQREAAYALGLKPWQTLWCIILPQAFRIVLPD
HHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IGNQFIAMQKDTALASAIALQELMGRARQAGLPRQHFFEALVVAALWYWLLTLILSFFQG
CCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLERYLAR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]