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The map label for this gene is livH [H]

Identifier: 86609532

GI number: 86609532

Start: 2180740

End: 2181609

Strand: Reverse

Name: livH [H]

Synonym: CYB_2084

Alternate gene names: 86609532

Gene position: 2181609-2180740 (Counterclockwise)

Preceding gene: 86609537

Following gene: 86609531

Centisome position: 71.61

GC content: 59.77

Gene sequence:

>870_bases
GTGACCCAACTGTTGCAACTTTTCATTTACGGCCTCGTCTTGGGCAGCATCTACGCCCTGGGAGCAATTGGGGTGTCGCT
GACCTTTGGCATTTTGCGCTTTGCCAACTTTGCCCACGGGGATCTGATGACCCTGGGGGCCTACTTCGGCCTGACATTTG
TTGGGTTGGGTTGGCCAATTGGGGTCAGCCTGCTCCCGGCAGCCTTGGCCACGGTACTTTGTGCAGTTGGGATCGACCAG
CTCATCTATCGCCGCCTGCGCCGGGAGGCACCAGTGATCTTGCTCATTTCTTCTTTTGGCACCGCCCTGATTCTGCGCAG
CCTGGTGCAGATCATCTGGGGGCCCAACAATCAGGTGTACCGCAGCGGGATCCAGTTGCCGTGGCGGCTTGGGGAGCTGC
GCATTAAGCCCGATTGGGCGGTAATCCTGGCGGGAACAGCCCTGTTGGTGGTGGCCCTGCATCTCTTCTTACAACGCACG
CGGGTGGGCAAAGCGATGCGGGCCATGGCCGACAATTTTGAGCTGGCCAAGATTACCGGCATTGATACGGAGCGAATCGT
TCTCTGGACTTGGGCCATTGGCGCAGCCTTGGCCTGTGCAGCAGGTGTGTTCCTGGGTATGGATACCCGGCTGCACCCCA
CCATGGGCTGGCGGCTATTGCTGCCCATTTTTGCAGCGGCCATTCTCGGCGGCATCGGTCGCCCTTACGGGGCTATTGCC
GGAGGAGTGGTGATCGGCCTGGCGGAAGAATTCTCGACCTTGGTGATCAACCCGGCCTATAAAACCGGGGTGGCCTTCGC
CATTTTGGTACTGCTGCTGATCTTCCGACCCACGGGATTACTGGGATCCCCGGGTGGGGGGGATGTCTGA

Upstream 100 bases:

>100_bases
CCGCTGGCGCGATCAGCCGTATCCTTCCGCTGTGCCGGACGGGATCCCGCTCTCGGCAAACCCGTGGCATTATCAGGGCA
AGGGGTTTTCGGGGGCAAGC

Downstream 100 bases:

>100_bases
TGTTGAGCTACGGCATTTTCTTTTTGATTTTGGTGGGGATCTACGGCGTGCTGGTGCTGGGCCTCAATATCCAGTGGGGC
TACGCCGGCATGTTCAACAT

Product: hydrophobic amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTQLLQLFIYGLVLGSIYALGAIGVSLTFGILRFANFAHGDLMTLGAYFGLTFVGLGWPIGVSLLPAALATVLCAVGIDQ
LIYRRLRREAPVILLISSFGTALILRSLVQIIWGPNNQVYRSGIQLPWRLGELRIKPDWAVILAGTALLVVALHLFLQRT
RVGKAMRAMADNFELAKITGIDTERIVLWTWAIGAALACAAGVFLGMDTRLHPTMGWRLLLPIFAAAILGGIGRPYGAIA
GGVVIGLAEEFSTLVINPAYKTGVAFAILVLLLIFRPTGLLGSPGGGDV

Sequences:

>Translated_289_residues
MTQLLQLFIYGLVLGSIYALGAIGVSLTFGILRFANFAHGDLMTLGAYFGLTFVGLGWPIGVSLLPAALATVLCAVGIDQ
LIYRRLRREAPVILLISSFGTALILRSLVQIIWGPNNQVYRSGIQLPWRLGELRIKPDWAVILAGTALLVVALHLFLQRT
RVGKAMRAMADNFELAKITGIDTERIVLWTWAIGAALACAAGVFLGMDTRLHPTMGWRLLLPIFAAAILGGIGRPYGAIA
GGVVIGLAEEFSTLVINPAYKTGVAFAILVLLLIFRPTGLLGSPGGGDV
>Mature_288_residues
TQLLQLFIYGLVLGSIYALGAIGVSLTFGILRFANFAHGDLMTLGAYFGLTFVGLGWPIGVSLLPAALATVLCAVGIDQL
IYRRLRREAPVILLISSFGTALILRSLVQIIWGPNNQVYRSGIQLPWRLGELRIKPDWAVILAGTALLVVALHLFLQRTR
VGKAMRAMADNFELAKITGIDTERIVLWTWAIGAALACAAGVFLGMDTRLHPTMGWRLLLPIFAAAILGGIGRPYGAIAG
GVVIGLAEEFSTLVINPAYKTGVAFAILVLLLIFRPTGLLGSPGGGDV

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=296, Percent_Identity=35.472972972973, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 30864; Mature: 30733

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLLQLFIYGLVLGSIYALGAIGVSLTFGILRFANFAHGDLMTLGAYFGLTFVGLGWPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHH
GVSLLPAALATVLCAVGIDQLIYRRLRREAPVILLISSFGTALILRSLVQIIWGPNNQVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHH
RSGIQLPWRLGELRIKPDWAVILAGTALLVVALHLFLQRTRVGKAMRAMADNFELAKITG
HCCCCCCEEECCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
IDTERIVLWTWAIGAALACAAGVFLGMDTRLHPTMGWRLLLPIFAAAILGGIGRPYGAIA
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
GGVVIGLAEEFSTLVINPAYKTGVAFAILVLLLIFRPTGLLGSPGGGDV
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQLLQLFIYGLVLGSIYALGAIGVSLTFGILRFANFAHGDLMTLGAYFGLTFVGLGWPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHH
GVSLLPAALATVLCAVGIDQLIYRRLRREAPVILLISSFGTALILRSLVQIIWGPNNQVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHH
RSGIQLPWRLGELRIKPDWAVILAGTALLVVALHLFLQRTRVGKAMRAMADNFELAKITG
HCCCCCCEEECCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
IDTERIVLWTWAIGAALACAAGVFLGMDTRLHPTMGWRLLLPIFAAAILGGIGRPYGAIA
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
GGVVIGLAEEFSTLVINPAYKTGVAFAILVLLLIFRPTGLLGSPGGGDV
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]