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The map label for this gene is etfD [H]

Identifier: 86609440

GI number: 86609440

Start: 2096113

End: 2097837

Strand: Direct

Name: etfD [H]

Synonym: CYB_1991

Alternate gene names: 86609440

Gene position: 2096113-2097837 (Clockwise)

Preceding gene: 86609436

Following gene: 86609441

Centisome position: 68.8

GC content: 59.42

Gene sequence:

>1725_bases
ATGAGTGAAGCCATCCGCTACGACCTTCTTTTGGTGGGGGGAAGCTCCTCCAACTTGATCTTGGCCCACCGCCTTTTGGA
TCTGGCCAAGCTCTCTGGGCTGAAAATCTCTATTGCCATTTTGGAAAAAGCCCGCCAATTCGGCGGTCACATCGTCAGTG
GCGCCATCTGCAACCTCCAAGTGATCGCCAAGCTCTTCCCCGATTTTGAAAGCCAAGGATTTCCCCACGAAGGCCGGGTG
GAAGCCAATCACTTGAGCGTGTTGGGATCCCAACAGCGCTGGGATCTGCCGGAAGCGGTGATCCCGCCGGGATTTCGCAA
GCAGGGACAGTTCATTCTCACCCTCAGCCACGTCATCCGTTGGCTGGCCGAAACCCTGCAGGAAAAAGCCAAAGGGATCC
CAAATGTTACCCTCGATGTGTTCCCCGGCTTTGCCGCCCATGAAATCCTCTACGAGGGGGAGCGGGTGATCGGGGTACGG
GCAAGCGATTCTGGCCAAGTGTACGAAGATTGCATCTTTGCCGAACTCACCTGCTTTGGCGACAAAGGCTTCATTTCCAA
AGATCTCATCGAGAAGTTTCAACTGCGCCCCAACCCGCAATTGTGGTCGGTGGGGGTCAAAGAGGTGTGGCAGATCCCCC
AGTCCCTGCAGGGGCAGGTGTGGCATACCTTGGGCTACCCGGTTTTGGATGGTAGCTTCAGCGGCGGCTTCGTCTATGGC
CTTAAGGAAAACCGCCTGGCTTTGGGTCTGATCATCGGCCTCGACAGCAAAAACCCCAACCTCAACCCCCAGCAACGTCT
GCAGGAGTTCAAGGCTCACCCCTGGATCCAGTCCCTAATTGCTGGCGGCAGGTTGCTCAAGTACGGGGCTGCCGTGATTC
CCGAAGGGGGCTACCACAGCCTGCCCACCCGGTTTGGCGTTGAGGGAGCCCTGCTGTTGGGGGATGCGCTGGGGGTGTTG
GATGTGGGCAGCTTGGCCGGGGTGGATAATGCCATGGAAACCGGCTATCTGGCGGCGGGCCTCATTCACGATGGCTTCTT
GAAAGGGGATCTGCGCATCCAAGCCGACTATCAAAAGGCGGTGATGGAAAGTGCAGTGGGGCAAAACCTCTACCGCAGTC
GCTATTTCCGCGAGGCTTTTTTGGAAAACTCCCGCCTGCTGGAAGAATACTTACCTCAGGTGTGCCGCAGCGTCGATGCC
GGCCACCCCTGGCTGGGATCCCTGCGCTGGGGCCTGCAGGATCCCGTTCGCCGCGGACGAGAAACTCTGCGCGCCTACAC
CCTGCTCACCGGGCGGGTCAGCCCCAGCGAGCCACCCCCGCGCAGCTATGTGGCCCCCCACGCTGCCATTCAAGCGGATT
TTGTGGCCCCCACAACCTTGGCTCCCCAGGAATTGGCCTCTCGACCGGGCTATTTCTCGCGGCCCGATGCGGTTTTTTTC
GCGGATCCCCGCTACCCCGAGGGTAACCGTCACATCCTGGAGTTCGACGCCGAAACCTGCCGCCGGTGCATCGCCACCTA
CGACAAGCTGAATCGCCCCACCCCCTGCGTTGCCGACTGCACAGCAGAGGTACACCACATCCGCGACCAAAATGGCATCC
GCTCCCATGCCATGTCTTTGGAAAACTGCATCCAGTGCCGCACCTGCGAGATCATCTGTCCCCACTTAAACTTGCGGGTC
AACCCCAGCTACGAGGGATCCGGGCCGGATTTCTATGGGCTGTAG

Upstream 100 bases:

>100_bases
CTCGCACCAGAGGCTTGAGAAGGTCTAAAGTTTTGCCCTCTTTCTCCCCTCCCCTTTTTAGGATACAGGCAGGGTATCCA
GAGCTACCGTGTGGGGGACT

Downstream 100 bases:

>100_bases
CCGTTGCTGAGGTTAACTCAGTTCGCTGCAGCTCGCCTGATCCTGGGGATCTAGCAATTATCCAAAGCAGAATGGATCTG
GCCATCTTGGCCGGCGATCC

Product: iron-sulfur cluster-binding protein

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MSEAIRYDLLLVGGSSSNLILAHRLLDLAKLSGLKISIAILEKARQFGGHIVSGAICNLQVIAKLFPDFESQGFPHEGRV
EANHLSVLGSQQRWDLPEAVIPPGFRKQGQFILTLSHVIRWLAETLQEKAKGIPNVTLDVFPGFAAHEILYEGERVIGVR
ASDSGQVYEDCIFAELTCFGDKGFISKDLIEKFQLRPNPQLWSVGVKEVWQIPQSLQGQVWHTLGYPVLDGSFSGGFVYG
LKENRLALGLIIGLDSKNPNLNPQQRLQEFKAHPWIQSLIAGGRLLKYGAAVIPEGGYHSLPTRFGVEGALLLGDALGVL
DVGSLAGVDNAMETGYLAAGLIHDGFLKGDLRIQADYQKAVMESAVGQNLYRSRYFREAFLENSRLLEEYLPQVCRSVDA
GHPWLGSLRWGLQDPVRRGRETLRAYTLLTGRVSPSEPPPRSYVAPHAAIQADFVAPTTLAPQELASRPGYFSRPDAVFF
ADPRYPEGNRHILEFDAETCRRCIATYDKLNRPTPCVADCTAEVHHIRDQNGIRSHAMSLENCIQCRTCEIICPHLNLRV
NPSYEGSGPDFYGL

Sequences:

>Translated_574_residues
MSEAIRYDLLLVGGSSSNLILAHRLLDLAKLSGLKISIAILEKARQFGGHIVSGAICNLQVIAKLFPDFESQGFPHEGRV
EANHLSVLGSQQRWDLPEAVIPPGFRKQGQFILTLSHVIRWLAETLQEKAKGIPNVTLDVFPGFAAHEILYEGERVIGVR
ASDSGQVYEDCIFAELTCFGDKGFISKDLIEKFQLRPNPQLWSVGVKEVWQIPQSLQGQVWHTLGYPVLDGSFSGGFVYG
LKENRLALGLIIGLDSKNPNLNPQQRLQEFKAHPWIQSLIAGGRLLKYGAAVIPEGGYHSLPTRFGVEGALLLGDALGVL
DVGSLAGVDNAMETGYLAAGLIHDGFLKGDLRIQADYQKAVMESAVGQNLYRSRYFREAFLENSRLLEEYLPQVCRSVDA
GHPWLGSLRWGLQDPVRRGRETLRAYTLLTGRVSPSEPPPRSYVAPHAAIQADFVAPTTLAPQELASRPGYFSRPDAVFF
ADPRYPEGNRHILEFDAETCRRCIATYDKLNRPTPCVADCTAEVHHIRDQNGIRSHAMSLENCIQCRTCEIICPHLNLRV
NPSYEGSGPDFYGL
>Mature_573_residues
SEAIRYDLLLVGGSSSNLILAHRLLDLAKLSGLKISIAILEKARQFGGHIVSGAICNLQVIAKLFPDFESQGFPHEGRVE
ANHLSVLGSQQRWDLPEAVIPPGFRKQGQFILTLSHVIRWLAETLQEKAKGIPNVTLDVFPGFAAHEILYEGERVIGVRA
SDSGQVYEDCIFAELTCFGDKGFISKDLIEKFQLRPNPQLWSVGVKEVWQIPQSLQGQVWHTLGYPVLDGSFSGGFVYGL
KENRLALGLIIGLDSKNPNLNPQQRLQEFKAHPWIQSLIAGGRLLKYGAAVIPEGGYHSLPTRFGVEGALLLGDALGVLD
VGSLAGVDNAMETGYLAAGLIHDGFLKGDLRIQADYQKAVMESAVGQNLYRSRYFREAFLENSRLLEEYLPQVCRSVDAG
HPWLGSLRWGLQDPVRRGRETLRAYTLLTGRVSPSEPPPRSYVAPHAAIQADFVAPTTLAPQELASRPGYFSRPDAVFFA
DPRYPEGNRHILEFDAETCRRCIATYDKLNRPTPCVADCTAEVHHIRDQNGIRSHAMSLENCIQCRTCEIICPHLNLRVN
PSYEGSGPDFYGL

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=597, Percent_Identity=28.643216080402, Blast_Score=209, Evalue=8e-54,
Organism=Escherichia coli, GI1787991, Length=409, Percent_Identity=27.3838630806846, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786227, Length=424, Percent_Identity=27.8301886792453, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI87082155, Length=321, Percent_Identity=28.3489096573209, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25144720, Length=607, Percent_Identity=27.6771004942339, Blast_Score=203, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324932, Length=611, Percent_Identity=27.1685761047463, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24652256, Length=594, Percent_Identity=28.956228956229, Blast_Score=207, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 63507; Mature: 63376

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAIRYDLLLVGGSSSNLILAHRLLDLAKLSGLKISIAILEKARQFGGHIVSGAICNLQ
CCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCEEEHHHHHHHH
VIAKLFPDFESQGFPHEGRVEANHLSVLGSQQRWDLPEAVIPPGFRKQGQFILTLSHVIR
HHHHHCCCHHCCCCCCCCCEEHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHH
WLAETLQEKAKGIPNVTLDVFPGFAAHEILYEGERVIGVRASDSGQVYEDCIFAELTCFG
HHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHEEEEC
DKGFISKDLIEKFQLRPNPQLWSVGVKEVWQIPQSLQGQVWHTLGYPVLDGSFSGGFVYG
CCCCCCHHHHHHHHCCCCCCEECCCHHHHHHCHHHHCCCEEHHCCCCEECCCCCCCEEEE
LKENRLALGLIIGLDSKNPNLNPQQRLQEFKAHPWIQSLIAGGRLLKYGAAVIPEGGYHS
ECCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEECCCCEECCCCCCCC
LPTRFGVEGALLLGDALGVLDVGSLAGVDNAMETGYLAAGLIHDGFLKGDLRIQADYQKA
CCHHHCCCCEEEHHCHHHHHCCCHHCCCCHHHHCCHHHHHHHHCCEEECCEEEEEHHHHH
VMESAVGQNLYRSRYFREAFLENSRLLEEYLPQVCRSVDAGHPWLGSLRWGLQDPVRRGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHH
ETLRAYTLLTGRVSPSEPPPRSYVAPHAAIQADFVAPTTLAPQELASRPGYFSRPDAVFF
HHHHHHHHEECCCCCCCCCCCCCCCCCHHHEECCCCCCCCCHHHHHCCCCCCCCCCEEEE
ADPRYPEGNRHILEFDAETCRRCIATYDKLNRPTPCVADCTAEVHHIRDQNGIRSHAMSL
ECCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
ENCIQCRTCEIICPHLNLRVNPSYEGSGPDFYGL
HHHHHHCEEEEECCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SEAIRYDLLLVGGSSSNLILAHRLLDLAKLSGLKISIAILEKARQFGGHIVSGAICNLQ
CCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCEEEHHHHHHHH
VIAKLFPDFESQGFPHEGRVEANHLSVLGSQQRWDLPEAVIPPGFRKQGQFILTLSHVIR
HHHHHCCCHHCCCCCCCCCEEHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHH
WLAETLQEKAKGIPNVTLDVFPGFAAHEILYEGERVIGVRASDSGQVYEDCIFAELTCFG
HHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHEEEEC
DKGFISKDLIEKFQLRPNPQLWSVGVKEVWQIPQSLQGQVWHTLGYPVLDGSFSGGFVYG
CCCCCCHHHHHHHHCCCCCCEECCCHHHHHHCHHHHCCCEEHHCCCCEECCCCCCCEEEE
LKENRLALGLIIGLDSKNPNLNPQQRLQEFKAHPWIQSLIAGGRLLKYGAAVIPEGGYHS
ECCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEECCCCEECCCCCCCC
LPTRFGVEGALLLGDALGVLDVGSLAGVDNAMETGYLAAGLIHDGFLKGDLRIQADYQKA
CCHHHCCCCEEEHHCHHHHHCCCHHCCCCHHHHCCHHHHHHHHCCEEECCEEEEEHHHHH
VMESAVGQNLYRSRYFREAFLENSRLLEEYLPQVCRSVDAGHPWLGSLRWGLQDPVRRGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHH
ETLRAYTLLTGRVSPSEPPPRSYVAPHAAIQADFVAPTTLAPQELASRPGYFSRPDAVFF
HHHHHHHHEECCCCCCCCCCCCCCCCCHHHEECCCCCCCCCHHHHHCCCCCCCCCCEEEE
ADPRYPEGNRHILEFDAETCRRCIATYDKLNRPTPCVADCTAEVHHIRDQNGIRSHAMSL
ECCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
ENCIQCRTCEIICPHLNLRVNPSYEGSGPDFYGL
HHHHHHCEEEEECCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]