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The map label for this gene is argB

Identifier: 86609146

GI number: 86609146

Start: 1761444

End: 1762382

Strand: Direct

Name: argB

Synonym: CYB_1687

Alternate gene names: 86609146

Gene position: 1761444-1762382 (Clockwise)

Preceding gene: 86609145

Following gene: 86609148

Centisome position: 57.82

GC content: 58.89

Gene sequence:

>939_bases
GTGCAAACCAACTCTTCCCTTTCTGAGGCGACCGGGTCGGCGTGTGATCCCCTTACGCGGGCGCAGATCCTCATCGAGGC
TTTACCCTACATTCAGCAGTACCAGGGCCGCGTTATTGTCATCAAATACGGCGGCGCAGCCATGGTGCACCAAGAGCGAC
GGGCCGAGGTGCTCCGAGACATCGTCTTTCTGGCCTGTGTGGGGATCCGCCCGGTGTTGGTGCATGGGGGGGGGCCGGAG
ATCAACAGTTGGCTACAAAAACTGGACATTCCCTTCAAGTTTGTGGATGGCTTGCGGGTTACCGATGCCGCCACCATGGA
AGTAGTGGAGATGGTGTTGGTGGGCAAGGTCAACAAGCAGATCGTGCAGCTCATCAGCTTGGCCGGCGGATCGGCGGTGG
GGCTGTGCGGGCGAGATGGCAACTTGATCAAGGCGCGATCCCAGGGCCGGGCGGAGATTGGCTTTGTTGGGGAAGTGAGC
AGTATCAACCCCCAGTTGCTGCAAACCCTATTGGAAGGTGGACAGATTCCGGTGATCTCCAGTGTGGCTGCCGATGAGAC
GGGCCAAGCCTACAACATCAACGCCGATACGGTGGCGGGAGAACTGGCGGCCTCTCTGGGGGCAGAAAAGCTGATTTTGC
TCACCGACACCCCTGGCATTCTCAAAGATCCTCAGGATCGCAGCTCTCTGATTACGTTGCTGGATATCGAGACGGCTCGC
CAGTTGATCCAAGCCGGTGTCGTCAAGGGCGGCATGATCCCGAAGGTGCAGTGTTGCATTCGCGCCTTGGCACAAGGGGT
GCGGGCAGCCCACATTCTGGATGGGGGATCCCCTCATTCCCTATTGCTGGAGCTGCTGACCGATGCCGGGGTGGGCACCA
AGCTTGTTCCTTCTCAGTTTTCCGCTCAGTTGGAAGGACTGAACAACGGATCCCGCTAA

Upstream 100 bases:

>100_bases
TGTCCCTATTGCCTTTGCTGGCGATCCCGTTCCATACCTGAGGATCTGCAGGATGCGATACTCTGGGTCAGGTTTTCTGG
ACTTCTAGGGACTTACAGCA

Downstream 100 bases:

>100_bases
GCTTCCTTGATAAAGCGAAGAATCTCCCGCACATGGCCGAGAAACTGGCTATCCACACTGAGCTGAGCCACAGCTTGGTG
GGTCTCCTGGCGCAATTGCC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MQTNSSLSEATGSACDPLTRAQILIEALPYIQQYQGRVIVIKYGGAAMVHQERRAEVLRDIVFLACVGIRPVLVHGGGPE
INSWLQKLDIPFKFVDGLRVTDAATMEVVEMVLVGKVNKQIVQLISLAGGSAVGLCGRDGNLIKARSQGRAEIGFVGEVS
SINPQLLQTLLEGGQIPVISSVAADETGQAYNINADTVAGELAASLGAEKLILLTDTPGILKDPQDRSSLITLLDIETAR
QLIQAGVVKGGMIPKVQCCIRALAQGVRAAHILDGGSPHSLLLELLTDAGVGTKLVPSQFSAQLEGLNNGSR

Sequences:

>Translated_312_residues
MQTNSSLSEATGSACDPLTRAQILIEALPYIQQYQGRVIVIKYGGAAMVHQERRAEVLRDIVFLACVGIRPVLVHGGGPE
INSWLQKLDIPFKFVDGLRVTDAATMEVVEMVLVGKVNKQIVQLISLAGGSAVGLCGRDGNLIKARSQGRAEIGFVGEVS
SINPQLLQTLLEGGQIPVISSVAADETGQAYNINADTVAGELAASLGAEKLILLTDTPGILKDPQDRSSLITLLDIETAR
QLIQAGVVKGGMIPKVQCCIRALAQGVRAAHILDGGSPHSLLLELLTDAGVGTKLVPSQFSAQLEGLNNGSR
>Mature_312_residues
MQTNSSLSEATGSACDPLTRAQILIEALPYIQQYQGRVIVIKYGGAAMVHQERRAEVLRDIVFLACVGIRPVLVHGGGPE
INSWLQKLDIPFKFVDGLRVTDAATMEVVEMVLVGKVNKQIVQLISLAGGSAVGLCGRDGNLIKARSQGRAEIGFVGEVS
SINPQLLQTLLEGGQIPVISSVAADETGQAYNINADTVAGELAASLGAEKLILLTDTPGILKDPQDRSSLITLLDIETAR
QLIQAGVVKGGMIPKVQCCIRALAQGVRAAHILDGGSPHSLLLELLTDAGVGTKLVPSQFSAQLEGLNNGSR

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=225, Percent_Identity=36.8888888888889, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=28.169014084507, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320913, Length=263, Percent_Identity=28.8973384030418, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SYNJB (Q2JHF7)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477908.1
- ProteinModelPortal:   Q2JHF7
- SMR:   Q2JHF7
- STRING:   Q2JHF7
- GeneID:   3901901
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1687
- TIGR:   CYB_1687
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q2JHF7
- ProtClustDB:   PRK00942
- BioCyc:   SSP321332:CYB_1687-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32874; Mature: 32874

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: BINDING 99-99 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTNSSLSEATGSACDPLTRAQILIEALPYIQQYQGRVIVIKYGGAAMVHQERRAEVLRD
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
IVFLACVGIRPVLVHGGGPEINSWLQKLDIPFKFVDGLRVTDAATMEVVEMVLVGKVNKQ
HHHHHHHCCCEEEEECCCCCHHHHHHHHCCCHHHHCCEEECHHHHHHHHHHHHHHHHHHH
IVQLISLAGGSAVGLCGRDGNLIKARSQGRAEIGFVGEVSSINPQLLQTLLEGGQIPVIS
HHHHHHHCCCCEEEEECCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEE
SVAADETGQAYNINADTVAGELAASLGAEKLILLTDTPGILKDPQDRSSLITLLDIETAR
HHCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHEEEEEEHHHHH
QLIQAGVVKGGMIPKVQCCIRALAQGVRAAHILDGGSPHSLLLELLTDAGVGTKLVPSQF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHH
SAQLEGLNNGSR
HHHHHCCCCCCC
>Mature Secondary Structure
MQTNSSLSEATGSACDPLTRAQILIEALPYIQQYQGRVIVIKYGGAAMVHQERRAEVLRD
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
IVFLACVGIRPVLVHGGGPEINSWLQKLDIPFKFVDGLRVTDAATMEVVEMVLVGKVNKQ
HHHHHHHCCCEEEEECCCCCHHHHHHHHCCCHHHHCCEEECHHHHHHHHHHHHHHHHHHH
IVQLISLAGGSAVGLCGRDGNLIKARSQGRAEIGFVGEVSSINPQLLQTLLEGGQIPVIS
HHHHHHHCCCCEEEEECCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEE
SVAADETGQAYNINADTVAGELAASLGAEKLILLTDTPGILKDPQDRSSLITLLDIETAR
HHCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHEEEEEEHHHHH
QLIQAGVVKGGMIPKVQCCIRALAQGVRAAHILDGGSPHSLLLELLTDAGVGTKLVPSQF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHH
SAQLEGLNNGSR
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA