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The map label for this gene is rbsK [H]

Identifier: 86608827

GI number: 86608827

Start: 1421431

End: 1422348

Strand: Direct

Name: rbsK [H]

Synonym: CYB_1353

Alternate gene names: 86608827

Gene position: 1421431-1422348 (Clockwise)

Preceding gene: 86608824

Following gene: 86608828

Centisome position: 46.66

GC content: 61.55

Gene sequence:

>918_bases
ATGGCAGGCCCGATCCGAGTGGTGGGTAGCTTGAACATGGATTTGGTGGTGCAGGTGCCCCATCATCCCGGCCCTGGGGA
AACGGTGCTGGGATCCGACTACGCCACCTACCCTGGCGGTAAGGGAGCCAATCAAGCGGTGGCAGCGGCGCGGGCGGGAG
CCCAGGTGGAAATGTGGGGAGCGGTGGGATCCGATGAGTTTGGGCGTCTGCTCCAAGAGAACCTGGAGCACAACGGCGTG
GATACCCGCCACCTGAGGCAGTTGGAGGGGCCCAGCGGCCTAGCTTTGATCACAGTGGATCCCGGCGGGCAAAACAGAAT
CGTGGTCAGCCCTGGAGCCAATGGTCGCTATCTGCCGGAGCATTTGCCTCCCTTTACCCCAGCGGCCCTGCTCCTGCTGC
AGCTGGAAATCCCCCTGCCCACTGTGCAGGCTGCAGCAGAACAAGCCTCTGCCCAAGGGATCCCGATTTTGCTCAACCCT
GCGCCCATCGTGCCATTGCCAGGATCCCTGTTGCGCCAGGTTCGCTACTTGGTGCTCAACGAAACCGAAGCGGCTGCCCT
TGCCCAATCCCCTGTGGAGACGCCGGAACAAGCCCAAAAGGTGGCTCAAGAACTGCAGAAACACGGGATCCCAGCCGTTA
TCCTTACCTTGGGAGGGGCAGGGCTGGTCTGGGCAGATGGGGAAGAAAGTGGCCATTGGCCAGCTCATCCTGTGGAAGTG
GTGGATACCACCGCTGCCGGAGATGGGTTTTGTGGGGCCTTAGCTGCTTGTTTGGCTGCCGGGGGATCCCTGAGGGAAGC
CCTGCGTTTTGCCAATGCCGCCGCTGCCTTGGTTGTAACCCGTGCAGGAGCCCAACCTAGCTTGCCCCAACGCTCTGAGA
TCGAGGCGTTTTTGGCCTCTGCCGTAGAAACAGCATAG

Upstream 100 bases:

>100_bases
TCCCTGGCCAAGACCGGCGGCTGATACAATAGCTGCCCAGGGATCCAAACCAAAGATCTCTGGATCTCTGCTTTTCCAAC
AGGATTTCCCCACAAGCCCG

Downstream 100 bases:

>100_bases
ACTGCTGCTTATCAAAAGTTTTCGACGTCTGCGGTGGAGAAGTTCATTGGCCGTTTGCGTGAGCGCTATGGGGAAACCGC
AACCTCCACAGGACAGAGCG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAGPIRVVGSLNMDLVVQVPHHPGPGETVLGSDYATYPGGKGANQAVAAARAGAQVEMWGAVGSDEFGRLLQENLEHNGV
DTRHLRQLEGPSGLALITVDPGGQNRIVVSPGANGRYLPEHLPPFTPAALLLLQLEIPLPTVQAAAEQASAQGIPILLNP
APIVPLPGSLLRQVRYLVLNETEAAALAQSPVETPEQAQKVAQELQKHGIPAVILTLGGAGLVWADGEESGHWPAHPVEV
VDTTAAGDGFCGALAACLAAGGSLREALRFANAAAALVVTRAGAQPSLPQRSEIEAFLASAVETA

Sequences:

>Translated_305_residues
MAGPIRVVGSLNMDLVVQVPHHPGPGETVLGSDYATYPGGKGANQAVAAARAGAQVEMWGAVGSDEFGRLLQENLEHNGV
DTRHLRQLEGPSGLALITVDPGGQNRIVVSPGANGRYLPEHLPPFTPAALLLLQLEIPLPTVQAAAEQASAQGIPILLNP
APIVPLPGSLLRQVRYLVLNETEAAALAQSPVETPEQAQKVAQELQKHGIPAVILTLGGAGLVWADGEESGHWPAHPVEV
VDTTAAGDGFCGALAACLAAGGSLREALRFANAAAALVVTRAGAQPSLPQRSEIEAFLASAVETA
>Mature_304_residues
AGPIRVVGSLNMDLVVQVPHHPGPGETVLGSDYATYPGGKGANQAVAAARAGAQVEMWGAVGSDEFGRLLQENLEHNGVD
TRHLRQLEGPSGLALITVDPGGQNRIVVSPGANGRYLPEHLPPFTPAALLLLQLEIPLPTVQAAAEQASAQGIPILLNPA
PIVPLPGSLLRQVRYLVLNETEAAALAQSPVETPEQAQKVAQELQKHGIPAVILTLGGAGLVWADGEESGHWPAHPVEVV
DTTAAGDGFCGALAACLAAGGSLREALRFANAAAALVVTRAGAQPSLPQRSEIEAFLASAVETA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=38.5135135135135, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=44.5544554455446, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI87082343, Length=307, Percent_Identity=32.2475570032573, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788491, Length=292, Percent_Identity=24.6575342465753, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081971, Length=310, Percent_Identity=26.4516129032258, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788417, Length=299, Percent_Identity=26.7558528428094, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789432, Length=263, Percent_Identity=29.277566539924, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=39.3333333333333, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=32.9305135951662, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=35.5481727574751, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24583886, Length=312, Percent_Identity=32.3717948717949, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31375; Mature: 31244

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPIRVVGSLNMDLVVQVPHHPGPGETVLGSDYATYPGGKGANQAVAAARAGAQVEMWG
CCCCEEEEECCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEC
AVGSDEFGRLLQENLEHNGVDTRHLRQLEGPSGLALITVDPGGQNRIVVSPGANGRYLPE
CCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCCCCHH
HLPPFTPAALLLLQLEIPLPTVQAAAEQASAQGIPILLNPAPIVPLPGSLLRQVRYLVLN
HCCCCCHHHEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHC
ETEAAALAQSPVETPEQAQKVAQELQKHGIPAVILTLGGAGLVWADGEESGHWPAHPVEV
CCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCEE
VDTTAAGDGFCGALAACLAAGGSLREALRFANAAAALVVTRAGAQPSLPQRSEIEAFLAS
EECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHH
AVETA
HHHCC
>Mature Secondary Structure 
AGPIRVVGSLNMDLVVQVPHHPGPGETVLGSDYATYPGGKGANQAVAAARAGAQVEMWG
CCCEEEEECCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEC
AVGSDEFGRLLQENLEHNGVDTRHLRQLEGPSGLALITVDPGGQNRIVVSPGANGRYLPE
CCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCCCCHH
HLPPFTPAALLLLQLEIPLPTVQAAAEQASAQGIPILLNPAPIVPLPGSLLRQVRYLVLN
HCCCCCHHHEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHC
ETEAAALAQSPVETPEQAQKVAQELQKHGIPAVILTLGGAGLVWADGEESGHWPAHPVEV
CCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCCEE
VDTTAAGDGFCGALAACLAAGGSLREALRFANAAAALVVTRAGAQPSLPQRSEIEAFLAS
EECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHH
AVETA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]