Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 86608779

GI number: 86608779

Start: 1366407

End: 1368746

Strand: Reverse

Name: dnaX [H]

Synonym: CYB_1304

Alternate gene names: 86608779

Gene position: 1368746-1366407 (Counterclockwise)

Preceding gene: 86608780

Following gene: 86608778

Centisome position: 44.93

GC content: 62.22

Gene sequence:

>2340_bases
ATGGCCACCGCTGGCAACTATGAACCCCTGCATTTAAAATACCGCCCGCAGCGCTTTGCCGATGTGGTCGGCCAAGGAGC
GGTGGTGCAAACGCTGGCCAATGCCATCCGGCTGGGGCGGGTGGCGCCTGCCTATTTGTTCTGCGGGCCGCGGGGCACGG
GAAAAACCTCCAGCGCCCGCATCTTGGCCAAGTCTTTGAATTGTGAACAGGGGCCGACGCCGGATCCCTGCCAGGCGTGC
AGCCAATGCCGCGCCATCACTGCGGGAGCCTCCCTGGATGTTCTCGAGATTGACGCGGCCAGCAACACCGGCGTAGACAA
CATCCGCGAGCTGATCGAGCGGGCCCAGTTTGCCCCGGTGAACAGCCGCTACAAAGTCTATGTCATCGACGAGTGCCACA
TGCTCAGCAATGCGGCCTTCAACGCCTTGCTGAAAACTCTTGAAGAGCCGCCCCCCCGCGTGGTATTTGTCCTGGCCACC
ACTGACCCGCAGCGGGTTTTGCCCACCATTGTTTCCCGCTGTCAGCGGTTTGACTTCCGCCGCATCCCCCTCGACGACAT
GGTGGCCCACCTGGGCAAGATCGCCGCCCAAGAAGGGATCCCTATCACGCCAGAGGCGCTGCAACTGGTGGCCCAACTTT
CCCAAGGGGGCCTGAGGGACGCCGAACGCCTGCTGGACCAGCTCAGCCTCTTGGAAGGATCCATCACCCCTGAAGCCGTT
TGGGACTTGGTGGGAGGGATCCCGGAACAGCAGCTTTTGGCTCTGATGGATGCGCTGCTGGCTCAGGATGTGCAGGCGGT
GCTCAGCCAAACTCGGCAATTGTTGGAGCGGGGCAAAGAGCCCTTAGCCCTGTTGCAGAACTTGGTGGCCCTTTACCGGG
ATCTGCTGCTGGTCAAGACAGCCCCCCAGCAACGGGAGTTGGTGGCTGTAACGGACTCCACCTGGGCAGCCCTGCAGCAA
CGGGCCCCTCGCTACTCGGTGGAGATACTGCTGGCAGCCCAGAGCCATCTGCGCCAGTGTGAGCCGCAAATTCGTCAAAG
CGGACAGCCCCAACTGTGGTTGGAAATTGCCCTAGTGGATCTGCTGGGCCAGCTGCGCCCAAGCATGGTGGCTGAGGATT
CAGCGGAACGGAGTCCTTTCCCAGCCCTTGACCTATCTCCTGCACCCCAGAGAACTCCCCCGGACGGGACAGCCCCTCCG
GCCCCTGCTGCGACCATCAGCCCATCAAGCCCATCAACTGTTGGTGAGATAGATGAATTAACTGTTGGGCCTTCAGCCTC
CCCTGCTGTTGCGTCGAGCCAGAAGGCAGATCGCGCTACTCGGACGGAGTCCTCGGAGCAGCCCAGAGAACCGGCAAGGG
ACGCCGCCACAGTCAAGCTGCTGCGCCCCCACTGGGACGAGTTCCTCAAGCGCCTCTCTCCCCTCACCAAGGCTCTGATG
GGATCCGGCCACCTGCACCAAGAGACTCCTGAAGCAATTACCCTCGCCTTTCCCAGCAAGGGTCTGGTGGAAAAAGTGCG
CAGCAAAGAAGCCGAACTGCGGTCGGTGCTCCACAACCTGCTGCAGCGCCCTGTGCAGCTCAACTTGATTGTGCAGCGCT
CCAGCGGGCCGCATGTTTCCATTCGCGTCAGCGGTGCGGAGTCCTCGGCACTGCTCAGCCGAGAAACAGACCTGCCCCCC
GCCCCCGTGGCCCCGGATCCTGTCACCACGCCGGGGTTGCAGAGCGATAGCACCAACAGTCGTGCTTCCTCAAGGGAGCC
CAGAGCAGAACCGCAGAGCCACGGCCTTGCCCGGCGACAGCAACATTCCCCTTCTGACTCCAACCCACCTTCGCCAGAGC
CTGAGCGGGACAATCCTATGGGTGGCCCCAAGGTGGCCGGCTTGGCAACCCAAGGACTTTCTCCCGCCGGTGCGAACAAA
GTGCTCCGCACCGCTGTCGCGACCGATTCTCCAAGTCGTGCAGAGCGCCGCGACACCCTGCACGGTGGGCAGTCCTTCGA
GCTAACCCAGGAGCTGGCGGAGATTGCCCGCTGTTTTGCCGACCACTTCAACGGCAGCTTGGTGGATTTGGAAGGGGTGT
TGGAGTCTGACGTGACGGGATCCACGGAAGAGCTCTCCTCAATAGAGGCTATAGAAGCCGAGGGATCCCCTGACCTGCTC
TCCGGTGAGACCTACGGCTCGCCAACAGGAGCAGAGCCGTCCGCGTCAGCGGGGCGGAGTCCTCATCCCGTAGACTTTCC
CAATGCAGTAAGGAATCCGTCCTACCGGCGTGAGCAGTCTTCTCAGCTTGCCGTTCGCCTCAGCGGGACGGAGTCCTTGG
AGGAGGAGGTGCCTTTTTAA

Upstream 100 bases:

>100_bases
TCGAGAAGCCAGAATAGGGGAGCCCCGGTGGGATCGCGTCAGCAGAGCAGAGCTCTTGCGCGGTTCCGGTTGGGGCGCTG
CTTGCTTGGAGATCCCGGAA

Downstream 100 bases:

>100_bases
GCGCTATCTAGCGCTATCTTAAGTTTGATAAAGCCAGCCTCATCTTGCCGACGATGACCTTCCCCATCTCTCCCTTAATT
CGCTGCGCTGTGCAGGCTCT

Product: DNA polymerase III, subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 778

Protein sequence:

>779_residues
MATAGNYEPLHLKYRPQRFADVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSARILAKSLNCEQGPTPDPCQAC
SQCRAITAGASLDVLEIDAASNTGVDNIRELIERAQFAPVNSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLAT
TDPQRVLPTIVSRCQRFDFRRIPLDDMVAHLGKIAAQEGIPITPEALQLVAQLSQGGLRDAERLLDQLSLLEGSITPEAV
WDLVGGIPEQQLLALMDALLAQDVQAVLSQTRQLLERGKEPLALLQNLVALYRDLLLVKTAPQQRELVAVTDSTWAALQQ
RAPRYSVEILLAAQSHLRQCEPQIRQSGQPQLWLEIALVDLLGQLRPSMVAEDSAERSPFPALDLSPAPQRTPPDGTAPP
APAATISPSSPSTVGEIDELTVGPSASPAVASSQKADRATRTESSEQPREPARDAATVKLLRPHWDEFLKRLSPLTKALM
GSGHLHQETPEAITLAFPSKGLVEKVRSKEAELRSVLHNLLQRPVQLNLIVQRSSGPHVSIRVSGAESSALLSRETDLPP
APVAPDPVTTPGLQSDSTNSRASSREPRAEPQSHGLARRQQHSPSDSNPPSPEPERDNPMGGPKVAGLATQGLSPAGANK
VLRTAVATDSPSRAERRDTLHGGQSFELTQELAEIARCFADHFNGSLVDLEGVLESDVTGSTEELSSIEAIEAEGSPDLL
SGETYGSPTGAEPSASAGRSPHPVDFPNAVRNPSYRREQSSQLAVRLSGTESLEEEVPF

Sequences:

>Translated_779_residues
MATAGNYEPLHLKYRPQRFADVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSARILAKSLNCEQGPTPDPCQAC
SQCRAITAGASLDVLEIDAASNTGVDNIRELIERAQFAPVNSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLAT
TDPQRVLPTIVSRCQRFDFRRIPLDDMVAHLGKIAAQEGIPITPEALQLVAQLSQGGLRDAERLLDQLSLLEGSITPEAV
WDLVGGIPEQQLLALMDALLAQDVQAVLSQTRQLLERGKEPLALLQNLVALYRDLLLVKTAPQQRELVAVTDSTWAALQQ
RAPRYSVEILLAAQSHLRQCEPQIRQSGQPQLWLEIALVDLLGQLRPSMVAEDSAERSPFPALDLSPAPQRTPPDGTAPP
APAATISPSSPSTVGEIDELTVGPSASPAVASSQKADRATRTESSEQPREPARDAATVKLLRPHWDEFLKRLSPLTKALM
GSGHLHQETPEAITLAFPSKGLVEKVRSKEAELRSVLHNLLQRPVQLNLIVQRSSGPHVSIRVSGAESSALLSRETDLPP
APVAPDPVTTPGLQSDSTNSRASSREPRAEPQSHGLARRQQHSPSDSNPPSPEPERDNPMGGPKVAGLATQGLSPAGANK
VLRTAVATDSPSRAERRDTLHGGQSFELTQELAEIARCFADHFNGSLVDLEGVLESDVTGSTEELSSIEAIEAEGSPDLL
SGETYGSPTGAEPSASAGRSPHPVDFPNAVRNPSYRREQSSQLAVRLSGTESLEEEVPF
>Mature_778_residues
ATAGNYEPLHLKYRPQRFADVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSARILAKSLNCEQGPTPDPCQACS
QCRAITAGASLDVLEIDAASNTGVDNIRELIERAQFAPVNSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLATT
DPQRVLPTIVSRCQRFDFRRIPLDDMVAHLGKIAAQEGIPITPEALQLVAQLSQGGLRDAERLLDQLSLLEGSITPEAVW
DLVGGIPEQQLLALMDALLAQDVQAVLSQTRQLLERGKEPLALLQNLVALYRDLLLVKTAPQQRELVAVTDSTWAALQQR
APRYSVEILLAAQSHLRQCEPQIRQSGQPQLWLEIALVDLLGQLRPSMVAEDSAERSPFPALDLSPAPQRTPPDGTAPPA
PAATISPSSPSTVGEIDELTVGPSASPAVASSQKADRATRTESSEQPREPARDAATVKLLRPHWDEFLKRLSPLTKALMG
SGHLHQETPEAITLAFPSKGLVEKVRSKEAELRSVLHNLLQRPVQLNLIVQRSSGPHVSIRVSGAESSALLSRETDLPPA
PVAPDPVTTPGLQSDSTNSRASSREPRAEPQSHGLARRQQHSPSDSNPPSPEPERDNPMGGPKVAGLATQGLSPAGANKV
LRTAVATDSPSRAERRDTLHGGQSFELTQELAEIARCFADHFNGSLVDLEGVLESDVTGSTEELSSIEAIEAEGSPDLLS
GETYGSPTGAEPSASAGRSPHPVDFPNAVRNPSYRREQSSQLAVRLSGTESLEEEVPF

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=289, Percent_Identity=28.3737024221453, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI31881687, Length=289, Percent_Identity=28.3737024221453, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI6677723, Length=254, Percent_Identity=27.1653543307087, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI194306571, Length=266, Percent_Identity=26.6917293233083, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI194306567, Length=266, Percent_Identity=26.6917293233083, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI31563534, Length=246, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI194306569, Length=185, Percent_Identity=26.4864864864865, Blast_Score=77, Evalue=7e-14,
Organism=Escherichia coli, GI1786676, Length=298, Percent_Identity=45.9731543624161, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI1787341, Length=150, Percent_Identity=34.6666666666667, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=319, Percent_Identity=26.0188087774295, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554730, Length=218, Percent_Identity=28.4403669724771, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17541988, Length=212, Percent_Identity=25.9433962264151, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=300, Percent_Identity=25.6666666666667, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322528, Length=328, Percent_Identity=24.6951219512195, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=249, Percent_Identity=24.0963855421687, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859927, Length=253, Percent_Identity=30.0395256916996, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921076, Length=253, Percent_Identity=26.8774703557312, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647857, Length=282, Percent_Identity=25.886524822695, Blast_Score=84, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 83728; Mature: 83597

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAGNYEPLHLKYRPQRFADVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSAR
CCCCCCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
ILAKSLNCEQGPTPDPCQACSQCRAITAGASLDVLEIDAASNTGVDNIRELIERAQFAPV
HHHHHCCCCCCCCCCHHHHHHHHHEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCC
NSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLATTDPQRVLPTIVSRCQRFDFR
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
RIPLDDMVAHLGKIAAQEGIPITPEALQLVAQLSQGGLRDAERLLDQLSLLEGSITPEAV
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHH
WDLVGGIPEQQLLALMDALLAQDVQAVLSQTRQLLERGKEPLALLQNLVALYRDLLLVKT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
APQQRELVAVTDSTWAALQQRAPRYSVEILLAAQSHLRQCEPQIRQSGQPQLWLEIALVD
CCCCCCEEEEECHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
LLGQLRPSMVAEDSAERSPFPALDLSPAPQRTPPDGTAPPAPAATISPSSPSTVGEIDEL
HHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHC
TVGPSASPAVASSQKADRATRTESSEQPREPARDAATVKLLRPHWDEFLKRLSPLTKALM
CCCCCCCCCHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSGHLHQETPEAITLAFPSKGLVEKVRSKEAELRSVLHNLLQRPVQLNLIVQRSSGPHVS
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEE
IRVSGAESSALLSRETDLPPAPVAPDPVTTPGLQSDSTNSRASSREPRAEPQSHGLARRQ
EEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHH
QHSPSDSNPPSPEPERDNPMGGPKVAGLATQGLSPAGANKVLRTAVATDSPSRAERRDTL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
HGGQSFELTQELAEIARCFADHFNGSLVDLEGVLESDVTGSTEELSSIEAIEAEGSPDLL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
SGETYGSPTGAEPSASAGRSPHPVDFPNAVRNPSYRREQSSQLAVRLSGTESLEEEVPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHCCCCEEEEECCCHHHHHCCCC
>Mature Secondary Structure 
ATAGNYEPLHLKYRPQRFADVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSAR
CCCCCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
ILAKSLNCEQGPTPDPCQACSQCRAITAGASLDVLEIDAASNTGVDNIRELIERAQFAPV
HHHHHCCCCCCCCCCHHHHHHHHHEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCC
NSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLATTDPQRVLPTIVSRCQRFDFR
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
RIPLDDMVAHLGKIAAQEGIPITPEALQLVAQLSQGGLRDAERLLDQLSLLEGSITPEAV
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHH
WDLVGGIPEQQLLALMDALLAQDVQAVLSQTRQLLERGKEPLALLQNLVALYRDLLLVKT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
APQQRELVAVTDSTWAALQQRAPRYSVEILLAAQSHLRQCEPQIRQSGQPQLWLEIALVD
CCCCCCEEEEECHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
LLGQLRPSMVAEDSAERSPFPALDLSPAPQRTPPDGTAPPAPAATISPSSPSTVGEIDEL
HHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHC
TVGPSASPAVASSQKADRATRTESSEQPREPARDAATVKLLRPHWDEFLKRLSPLTKALM
CCCCCCCCCHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSGHLHQETPEAITLAFPSKGLVEKVRSKEAELRSVLHNLLQRPVQLNLIVQRSSGPHVS
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEE
IRVSGAESSALLSRETDLPPAPVAPDPVTTPGLQSDSTNSRASSREPRAEPQSHGLARRQ
EEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHH
QHSPSDSNPPSPEPERDNPMGGPKVAGLATQGLSPAGANKVLRTAVATDSPSRAERRDTL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
HGGQSFELTQELAEIARCFADHFNGSLVDLEGVLESDVTGSTEELSSIEAIEAEGSPDLL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
SGETYGSPTGAEPSASAGRSPHPVDFPNAVRNPSYRREQSSQLAVRLSGTESLEEEVPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHCCCCEEEEECCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]