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The map label for this gene is alr [H]

Identifier: 86608143

GI number: 86608143

Start: 669567

End: 670841

Strand: Reverse

Name: alr [H]

Synonym: CYB_0655

Alternate gene names: 86608143

Gene position: 670841-669567 (Counterclockwise)

Preceding gene: 86608144

Following gene: 86608142

Centisome position: 22.02

GC content: 61.1

Gene sequence:

>1275_bases
GTGAATCGAGAACCGGTCGCGCCGGCGGCGCAGGGCACTTTGAGAGCAGCTGCTCTGGGAGTGCAGGGCAATACTTGGAG
AGAGGGATCCCAGAGGGCAAATCCCTCGGCGGAGCTGGATTGCGCGATTGACCTGGAGCTGTTGACCAGTCGGGCTTGGG
TGGAAATTGACGCAGCCCAGCTGCGAGAAAACCTGCGGCTGTTGCAGAGGCGCCTAGGCTCAAACGTCGAGATCTGGGCG
GTGGTGAAGGCCAATGCCTACGGGCATGGGGCGCAGTTGGTGGCTCCCGTGGCTGTTGCGGCTGGGGCCAAGGGGCTATG
TGTGGCCACCCTGGCCGAAGGGATCGAGTTGCGGCAAACGGGGCTGCAGGCTCCGGTTCTGGTGTTGGGAGCTTTGAATA
CTTGGGCGGAGCTACAGCAGGCCATGGCAGCCCGGCTGGAGGTCAGCCTCACCTGCACAGACCAAATCCCGCTGATGCGC
CAGGTAGCCCGTTGGGCCGGGCGACCCATCCCGGTGCATGTCAATGTGGATACGGGTATGACCCGTTTGGGGATCCCCTG
GAAGGAAGCTGCAGCCGTGTGGGGGCAGATTTGTCGGATCCCGGAGCTGGAAGGCTGTAGCTTGTTTTCCCATCTGGCGA
CGGCGGACGAGCCCCATTCTCCGGTCATGGAACAGCAGCACGCCCGCTTTGCCCAGGTGGTGGAACAGATCCGTCAAGCC
GGGGATCCCTTGCCGGCGCTGCATCTGGATAACTCAGCCGGTGCTTTAACCCATCTCCACTACTCCCGTGTGCGTTTGGG
GTTGGTCCTCTATGGCCTGTCCCCTGCCCCTCACTTGCCGGTGCCAGGTCTGCAGCCAATTCTGCGGCTCAAGGCGCGGC
TGTCCCACATCCAAACTGTGCCTGCTCAAACTGGCGTGAGCTATGGGCATCGCTACATCACCTCTCGCCCCAGTCGCATT
GCCACTCTGGCCATCGGCTATGCGGATGGGATCCCACGGCGGCTTTCCGGCTGGCTGCGAGGATGGGTGCGCGGCGGCTT
GATCCAACAGGTGGGCACAATCACGATGGATCAATGTATGTGGGATGTAACCGAGAGGCCGGATATCCAGGTGGGGGATG
TGGTGGAGCTGCTGGGCCCCAATCTGGCAAATGCGGGTTTATCTGTGCAGGATTGGGCCGATCAGTTGGGTACTATTTCC
TATGAGTTGCTGTGTGGACTTTCTGCCCGTCTGCCAAGAGTGTTGGTTAATTCTCTGGGTTTTGATGATGCCTGA

Upstream 100 bases:

>100_bases
TTGGGATCCCAGACGTGCCGTTGCTGTGGATGGCGCCGGAGTGGACTTTGCGCTAAACCTAAATCTAATCAGGACGGGTT
TTGGGTGTGGGGGGTGAACG

Downstream 100 bases:

>100_bases
CACGACAGATTGGATTGCCTCAAGCACGGATAGGAGCGGGCCAGAGGCTGTTCGCGTCGGCAGCAGAGGGCTTGACTTGA
CGTGTCAACAGAGAGTAGAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNREPVAPAAQGTLRAAALGVQGNTWREGSQRANPSAELDCAIDLELLTSRAWVEIDAAQLRENLRLLQRRLGSNVEIWA
VVKANAYGHGAQLVAPVAVAAGAKGLCVATLAEGIELRQTGLQAPVLVLGALNTWAELQQAMAARLEVSLTCTDQIPLMR
QVARWAGRPIPVHVNVDTGMTRLGIPWKEAAAVWGQICRIPELEGCSLFSHLATADEPHSPVMEQQHARFAQVVEQIRQA
GDPLPALHLDNSAGALTHLHYSRVRLGLVLYGLSPAPHLPVPGLQPILRLKARLSHIQTVPAQTGVSYGHRYITSRPSRI
ATLAIGYADGIPRRLSGWLRGWVRGGLIQQVGTITMDQCMWDVTERPDIQVGDVVELLGPNLANAGLSVQDWADQLGTIS
YELLCGLSARLPRVLVNSLGFDDA

Sequences:

>Translated_424_residues
MNREPVAPAAQGTLRAAALGVQGNTWREGSQRANPSAELDCAIDLELLTSRAWVEIDAAQLRENLRLLQRRLGSNVEIWA
VVKANAYGHGAQLVAPVAVAAGAKGLCVATLAEGIELRQTGLQAPVLVLGALNTWAELQQAMAARLEVSLTCTDQIPLMR
QVARWAGRPIPVHVNVDTGMTRLGIPWKEAAAVWGQICRIPELEGCSLFSHLATADEPHSPVMEQQHARFAQVVEQIRQA
GDPLPALHLDNSAGALTHLHYSRVRLGLVLYGLSPAPHLPVPGLQPILRLKARLSHIQTVPAQTGVSYGHRYITSRPSRI
ATLAIGYADGIPRRLSGWLRGWVRGGLIQQVGTITMDQCMWDVTERPDIQVGDVVELLGPNLANAGLSVQDWADQLGTIS
YELLCGLSARLPRVLVNSLGFDDA
>Mature_424_residues
MNREPVAPAAQGTLRAAALGVQGNTWREGSQRANPSAELDCAIDLELLTSRAWVEIDAAQLRENLRLLQRRLGSNVEIWA
VVKANAYGHGAQLVAPVAVAAGAKGLCVATLAEGIELRQTGLQAPVLVLGALNTWAELQQAMAARLEVSLTCTDQIPLMR
QVARWAGRPIPVHVNVDTGMTRLGIPWKEAAAVWGQICRIPELEGCSLFSHLATADEPHSPVMEQQHARFAQVVEQIRQA
GDPLPALHLDNSAGALTHLHYSRVRLGLVLYGLSPAPHLPVPGLQPILRLKARLSHIQTVPAQTGVSYGHRYITSRPSRI
ATLAIGYADGIPRRLSGWLRGWVRGGLIQQVGTITMDQCMWDVTERPDIQVGDVVELLGPNLANAGLSVQDWADQLGTIS
YELLCGLSARLPRVLVNSLGFDDA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=367, Percent_Identity=32.1525885558583, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790487, Length=372, Percent_Identity=30.6451612903226, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 45817; Mature: 45817

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNREPVAPAAQGTLRAAALGVQGNTWREGSQRANPSAELDCAIDLELLTSRAWVEIDAAQ
CCCCCCCCCHHCCHHHHEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEECHHH
LRENLRLLQRRLGSNVEIWAVVKANAYGHGAQLVAPVAVAAGAKGLCVATLAEGIELRQT
HHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHH
GLQAPVLVLGALNTWAELQQAMAARLEVSLTCTDQIPLMRQVARWAGRPIPVHVNVDTGM
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCC
TRLGIPWKEAAAVWGQICRIPELEGCSLFSHLATADEPHSPVMEQQHARFAQVVEQIRQA
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHC
GDPLPALHLDNSAGALTHLHYSRVRLGLVLYGLSPAPHLPVPGLQPILRLKARLSHIQTV
CCCCCEEEECCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
PAQTGVSYGHRYITSRPSRIATLAIGYADGIPRRLSGWLRGWVRGGLIQQVGTITMDQCM
CHHHCHHHCCHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
WDVTERPDIQVGDVVELLGPNLANAGLSVQDWADQLGTISYELLCGLSARLPRVLVNSLG
HHCCCCCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCC
FDDA
CCCC
>Mature Secondary Structure
MNREPVAPAAQGTLRAAALGVQGNTWREGSQRANPSAELDCAIDLELLTSRAWVEIDAAQ
CCCCCCCCCHHCCHHHHEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEECHHH
LRENLRLLQRRLGSNVEIWAVVKANAYGHGAQLVAPVAVAAGAKGLCVATLAEGIELRQT
HHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHH
GLQAPVLVLGALNTWAELQQAMAARLEVSLTCTDQIPLMRQVARWAGRPIPVHVNVDTGM
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCC
TRLGIPWKEAAAVWGQICRIPELEGCSLFSHLATADEPHSPVMEQQHARFAQVVEQIRQA
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHC
GDPLPALHLDNSAGALTHLHYSRVRLGLVLYGLSPAPHLPVPGLQPILRLKARLSHIQTV
CCCCCEEEECCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
PAQTGVSYGHRYITSRPSRIATLAIGYADGIPRRLSGWLRGWVRGGLIQQVGTITMDQCM
CHHHCHHHCCHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
WDVTERPDIQVGDVVELLGPNLANAGLSVQDWADQLGTISYELLCGLSARLPRVLVNSLG
HHCCCCCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCC
FDDA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]