Click here to switch to the map view.

The map label for this gene is sppA-1 [H]

Identifier: 86608144

GI number: 86608144

Start: 670886

End: 672040

Strand: Reverse

Name: sppA-1 [H]

Synonym: CYB_0656

Alternate gene names: 86608144

Gene position: 672040-670886 (Counterclockwise)

Preceding gene: 86608145

Following gene: 86608143

Centisome position: 22.06

GC content: 61.3

Gene sequence:

>1155_bases
ATGGCTCAACCGGGGGGAAGCAACAGTGGGGTTTGCTCGGCCCTCAGCCTTTTGTTGCCCGGCATCCCAGGAAGCCCGCG
GGGTGGTAGAACGGAGTCAGTGGCAATTGAGGGGCCTGTGACACAAGAAACTCAGCTTAACCGCATTTTGGCGGCTTCTT
TGCTGGTCGTCTGCCTTATTGCGGCCATTGTCGGGGGCACGCGCCCTGCCCCAGAGCCTACCCGAGGCGGGGTTGGCCTA
GAGGCTGCACGGGGGGCGGAGCGCATCGAGGTGGTCACCCTGGAAGGAACGATAGGCGGCCCAGGGGGTTCGACTTTGGT
AGGCCTGCCCACTTCTCCTGTGGAACAGTTGCGGGAGGCAGCACGGGATCCCTCTGTCAAGGCTGTATTGCTGCGCATCA
ACAGTCCCGGCGGAGCTGTGGGATCCAGCCAGGAACTCTACCGTGCCGTAACTGCTCTGCACGAGGCGGACAAGCCGGTG
ATCGCTATCCTAGAAAACATTGCTGCCAGTGGGGGGTACTACGTGGCCAGCGCTGCCGACAAAATCTATGCCAACCCCGG
CACCCTGACCGGCAGCATAGGGGCTATCATCAGCGGCCTCAGCTTTGGTAAGCTGCTGGAGAACTACGGCATAGAGCCGC
AGACCTTCAAAACCGGCGAGTACAAAGACCTTCTCTCTCCTTTCCGCAGTGCCACTCCTCAAGAGCAGCGCCTTCTGCAA
AACTTGGTGGAGGATACCCTCGAGCAGTTCATTCGCGATGTGGCCCAAGGACGCCAGCACTTGCCAGAAAAGGCAGATGA
GGTGCTGGAAGCAGAGATGATCGCGCGACGGCAGAGCTTGGATGAAGACCGGGTGCGACAATTGGCCGATGGACGCATCT
TCACCGGGGCGCAAGCTGTGGAGGTGGGCTTGGTGGATGCTTTGGGGGGGTACACGGAGGCGGTGGAGGATCTGCGGCGC
ATGACCGGGGATCCCTCTTTGTCGCCGGCGGGTGAGGGAGAGGGCTTCCAACGAGTACTGCGACGCCTGTTAAGCCAAGG
ACTGTCCTCGCAAAGGCAAGCCGCTTGGCTGGGCCGGCTGTTGGAGAGCAACGAGGCTGTTGGGATCCCAGACGTGCCGT
TGCTGTGGATGGCGCCGGAGTGGACTTTGCGCTAA

Upstream 100 bases:

>100_bases
CTATTCCATTCTACACCTGCAGCCTGTAGAAGCTGCCTTATTGGTAAAAAGTGCTGGGATCCCATACTAGATAAGGGGAG
GATCCTTGTCAATAGTTTGG

Downstream 100 bases:

>100_bases
ACCTAAATCTAATCAGGACGGGTTTTGGGTGTGGGGGGTGAACGGTGAATCGAGAACCGGTCGCGCCGGCGGCGCAGGGC
ACTTTGAGAGCAGCTGCTCT

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MAQPGGSNSGVCSALSLLLPGIPGSPRGGRTESVAIEGPVTQETQLNRILAASLLVVCLIAAIVGGTRPAPEPTRGGVGL
EAARGAERIEVVTLEGTIGGPGGSTLVGLPTSPVEQLREAARDPSVKAVLLRINSPGGAVGSSQELYRAVTALHEADKPV
IAILENIAASGGYYVASAADKIYANPGTLTGSIGAIISGLSFGKLLENYGIEPQTFKTGEYKDLLSPFRSATPQEQRLLQ
NLVEDTLEQFIRDVAQGRQHLPEKADEVLEAEMIARRQSLDEDRVRQLADGRIFTGAQAVEVGLVDALGGYTEAVEDLRR
MTGDPSLSPAGEGEGFQRVLRRLLSQGLSSQRQAAWLGRLLESNEAVGIPDVPLLWMAPEWTLR

Sequences:

>Translated_384_residues
MAQPGGSNSGVCSALSLLLPGIPGSPRGGRTESVAIEGPVTQETQLNRILAASLLVVCLIAAIVGGTRPAPEPTRGGVGL
EAARGAERIEVVTLEGTIGGPGGSTLVGLPTSPVEQLREAARDPSVKAVLLRINSPGGAVGSSQELYRAVTALHEADKPV
IAILENIAASGGYYVASAADKIYANPGTLTGSIGAIISGLSFGKLLENYGIEPQTFKTGEYKDLLSPFRSATPQEQRLLQ
NLVEDTLEQFIRDVAQGRQHLPEKADEVLEAEMIARRQSLDEDRVRQLADGRIFTGAQAVEVGLVDALGGYTEAVEDLRR
MTGDPSLSPAGEGEGFQRVLRRLLSQGLSSQRQAAWLGRLLESNEAVGIPDVPLLWMAPEWTLR
>Mature_383_residues
AQPGGSNSGVCSALSLLLPGIPGSPRGGRTESVAIEGPVTQETQLNRILAASLLVVCLIAAIVGGTRPAPEPTRGGVGLE
AARGAERIEVVTLEGTIGGPGGSTLVGLPTSPVEQLREAARDPSVKAVLLRINSPGGAVGSSQELYRAVTALHEADKPVI
AILENIAASGGYYVASAADKIYANPGTLTGSIGAIISGLSFGKLLENYGIEPQTFKTGEYKDLLSPFRSATPQEQRLLQN
LVEDTLEQFIRDVAQGRQHLPEKADEVLEAEMIARRQSLDEDRVRQLADGRIFTGAQAVEVGLVDALGGYTEAVEDLRRM
TGDPSLSPAGEGEGFQRVLRRLLSQGLSSQRQAAWLGRLLESNEAVGIPDVPLLWMAPEWTLR

Specific function: Digestion of the cleaved signal peptides [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=245, Percent_Identity=33.8775510204082, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787527, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 40512; Mature: 40380

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPGGSNSGVCSALSLLLPGIPGSPRGGRTESVAIEGPVTQETQLNRILAASLLVVCLI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
AAIVGGTRPAPEPTRGGVGLEAARGAERIEVVTLEGTIGGPGGSTLVGLPTSPVEQLREA
HHHHCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCEEECCCCHHHHHHHH
ARDPSVKAVLLRINSPGGAVGSSQELYRAVTALHEADKPVIAILENIAASGGYYVASAAD
HCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCH
KIYANPGTLTGSIGAIISGLSFGKLLENYGIEPQTFKTGEYKDLLSPFRSATPQEQRLLQ
HHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
NLVEDTLEQFIRDVAQGRQHLPEKADEVLEAEMIARRQSLDEDRVRQLADGRIFTGAQAV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCHHH
EVGLVDALGGYTEAVEDLRRMTGDPSLSPAGEGEGFQRVLRRLLSQGLSSQRQAAWLGRL
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESNEAVGIPDVPLLWMAPEWTLR
HHCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AQPGGSNSGVCSALSLLLPGIPGSPRGGRTESVAIEGPVTQETQLNRILAASLLVVCLI
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
AAIVGGTRPAPEPTRGGVGLEAARGAERIEVVTLEGTIGGPGGSTLVGLPTSPVEQLREA
HHHHCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCEEECCCCHHHHHHHH
ARDPSVKAVLLRINSPGGAVGSSQELYRAVTALHEADKPVIAILENIAASGGYYVASAAD
HCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCH
KIYANPGTLTGSIGAIISGLSFGKLLENYGIEPQTFKTGEYKDLLSPFRSATPQEQRLLQ
HHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
NLVEDTLEQFIRDVAQGRQHLPEKADEVLEAEMIARRQSLDEDRVRQLADGRIFTGAQAV
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCHHH
EVGLVDALGGYTEAVEDLRRMTGDPSLSPAGEGEGFQRVLRRLLSQGLSSQRQAAWLGRL
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESNEAVGIPDVPLLWMAPEWTLR
HHCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]