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The map label for this gene is pheA [H]

Identifier: 86608141

GI number: 86608141

Start: 668015

End: 669001

Strand: Reverse

Name: pheA [H]

Synonym: CYB_0653

Alternate gene names: 86608141

Gene position: 669001-668015 (Counterclockwise)

Preceding gene: 86608142

Following gene: 86608139

Centisome position: 21.96

GC content: 59.88

Gene sequence:

>987_bases
ATGGAGCTGCGCTCCGCTAGCGCGAACGTTTCCCCTTCGCCAGTGGCCTTCCTCGGCCCTGCTGGAACCTACACAGAGTT
AGCAGCTCTGCTGGCCTGCCCTGAGCAGCCTCACCTGCACAGCCAGGGATCCCACCCCTTAGTGCCTTATCCAACGATCA
GCGCCTGTCTAGAGGCGGTAGCTGCCGGCCAGCAACAATGGGCGGTGGTGCCGGTGGAAAACTCGGTGGAGGGGGGGGTC
TCGATGACCTTAGACGCCCTCTGGCAACTGGAGGGGCTAGGGATTCGGCAGGCGCTGATCCTGCCCATTCGCCATGCCCT
CATCGGACGTGCCTCGCGGTTGGAGCAAATTGAGCAGGTCTACTCCCACCCGCAAGCTTTGGCCCAATGTCAGGCTTGGC
TGAGATCCCATCTGCCCCAGGCCACTTTGATCCCAACCCGCTCGACCACCGAAGAATTGGATCGCCTGCAGGAGCAGCCC
AGCGCTGCCGTCATCGCCTCAGAACGAGCTGCCACCCTCTACCAACTGCCGGTCTTGGCCTGCCCGATCAACGATCACCC
CGACAATTGCACTCGCTTTTGGGTTATTGGCCGTGCGCCGCTCTCGCGTTCCGGTCAACAGGGTGAAACCTCTGCCGATC
CTGCTTCTCCGGGGGGATCCCATACTTCCTTAGCCTTCAGCCTCCCCCACAACGTGCCGGGAGCGCTGCTGAAACCTCTG
CAAGTGTTTGCGGAGCGAGGCCTGAATATGTCTCGCATTGAGTCGCGCCCCACTAAAAAATCGGCAGGGACGTATGTCTT
TTTTGTCGATTTGGAGAACCCTATCGGCCAACCCTATTTGGATGCCGAGGTGGTTGCGGCGCTGGAATCAATTGCTGAAA
CCTTGAAGCTCTTCGGCAGCTACCCTGTGCATGACCTCTGCAAACAAGGGGATCTATCCCAAGTAGCAAAAGCCCTGCCC
TCTGAGGGGAAAGCGCGTCCAACGTAG

Upstream 100 bases:

>100_bases
AATCCCCGTTGCCCAGAACCTGAATGTCCTTTGCTGCTGCGCGACGTCGAGGCGATAGAGTTAGAACTGGCCCCTAGCGA
CAATTGAAGGAATGGCTCTG

Downstream 100 bases:

>100_bases
AATCGAAATGACCAAGGACTGCTGTCTTGAGCGCTCAGGCAGACCAGGATCACTTCACAGAGCTCGATAACCTTGCCAGG
CTTGCCAAAAAATGTAAAGA

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MELRSASANVSPSPVAFLGPAGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLEAVAAGQQQWAVVPVENSVEGGV
SMTLDALWQLEGLGIRQALILPIRHALIGRASRLEQIEQVYSHPQALAQCQAWLRSHLPQATLIPTRSTTEELDRLQEQP
SAAVIASERAATLYQLPVLACPINDHPDNCTRFWVIGRAPLSRSGQQGETSADPASPGGSHTSLAFSLPHNVPGALLKPL
QVFAERGLNMSRIESRPTKKSAGTYVFFVDLENPIGQPYLDAEVVAALESIAETLKLFGSYPVHDLCKQGDLSQVAKALP
SEGKARPT

Sequences:

>Translated_328_residues
MELRSASANVSPSPVAFLGPAGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLEAVAAGQQQWAVVPVENSVEGGV
SMTLDALWQLEGLGIRQALILPIRHALIGRASRLEQIEQVYSHPQALAQCQAWLRSHLPQATLIPTRSTTEELDRLQEQP
SAAVIASERAATLYQLPVLACPINDHPDNCTRFWVIGRAPLSRSGQQGETSADPASPGGSHTSLAFSLPHNVPGALLKPL
QVFAERGLNMSRIESRPTKKSAGTYVFFVDLENPIGQPYLDAEVVAALESIAETLKLFGSYPVHDLCKQGDLSQVAKALP
SEGKARPT
>Mature_328_residues
MELRSASANVSPSPVAFLGPAGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLEAVAAGQQQWAVVPVENSVEGGV
SMTLDALWQLEGLGIRQALILPIRHALIGRASRLEQIEQVYSHPQALAQCQAWLRSHLPQATLIPTRSTTEELDRLQEQP
SAAVIASERAATLYQLPVLACPINDHPDNCTRFWVIGRAPLSRSGQQGETSADPASPGGSHTSLAFSLPHNVPGALLKPL
QVFAERGLNMSRIESRPTKKSAGTYVFFVDLENPIGQPYLDAEVVAALESIAETLKLFGSYPVHDLCKQGDLSQVAKALP
SEGKARPT

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=294, Percent_Identity=30.952380952381, Blast_Score=107, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324013, Length=335, Percent_Identity=27.7611940298507, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 35160; Mature: 35160

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRSASANVSPSPVAFLGPAGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLEAV
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AAGQQQWAVVPVENSVEGGVSMTLDALWQLEGLGIRQALILPIRHALIGRASRLEQIEQV
HCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
YSHPQALAQCQAWLRSHLPQATLIPTRSTTEELDRLQEQPSAAVIASERAATLYQLPVLA
HHCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEE
CPINDHPDNCTRFWVIGRAPLSRSGQQGETSADPASPGGSHTSLAFSLPHNVPGALLKPL
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
QVFAERGLNMSRIESRPTKKSAGTYVFFVDLENPIGQPYLDAEVVAALESIAETLKLFGS
HHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
YPVHDLCKQGDLSQVAKALPSEGKARPT
CCHHHHHCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MELRSASANVSPSPVAFLGPAGTYTELAALLACPEQPHLHSQGSHPLVPYPTISACLEAV
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AAGQQQWAVVPVENSVEGGVSMTLDALWQLEGLGIRQALILPIRHALIGRASRLEQIEQV
HCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
YSHPQALAQCQAWLRSHLPQATLIPTRSTTEELDRLQEQPSAAVIASERAATLYQLPVLA
HHCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCEEE
CPINDHPDNCTRFWVIGRAPLSRSGQQGETSADPASPGGSHTSLAFSLPHNVPGALLKPL
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
QVFAERGLNMSRIESRPTKKSAGTYVFFVDLENPIGQPYLDAEVVAALESIAETLKLFGS
HHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
YPVHDLCKQGDLSQVAKALPSEGKARPT
CCHHHHHCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]