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The map label for this gene is murA [H]

Identifier: 86607597

GI number: 86607597

Start: 110944

End: 112338

Strand: Direct

Name: murA [H]

Synonym: CYB_0095

Alternate gene names: 86607597

Gene position: 110944-112338 (Clockwise)

Preceding gene: 86607592

Following gene: 86607598

Centisome position: 3.64

GC content: 60.79

Gene sequence:

>1395_bases
TTGAAAGGTTTTGACAATCGCGTCAGCGGGGCGGATCCCCTAGAGCCTGGCCTGACGCCGCCCCAGACCGGCATGGCAAC
CGCGCCAGAGATGATGGGGCCAGTGCTGAAAATCATTGGCAAGCAGACCCTGAGTGGCCACATCCCTATTGGCGGGGCAA
AAAACTCTGCCTTGGCGCTGATGGCCGGGGCCATCTTGGCTCCTGAGGCCTGTCGAATTCACAACGTGCCGCGTCTGCTG
GACATTGAACGCATGGGGCAGATCCTGGCCACGCTGGGAGTTAAGGTTTCCCATGTTGGCAATACCCTGGACCTGGATGC
CAGCTCCCTCAAAACCTCTCAAGCCCCTTATGAATTGGTCAGCCAGTTGCGGGCCAGCTTTTTCATCATAGGGCCTCTGT
TGGCGCGGCTGGGGGTGGCCAGAGTTCCCCTGCCCGGTGGCTGTGCGATCGGGTCTCGTCCTGTGGATCTGCATGTGCGG
GGTCTACAAGCCTTGGGGGCAACGGTCCAAATCGAGCATGGGGTGGTTCATGCCTATGCCCGTAAACTGTTGGGAACCCG
TATTTACCTGGACTATCCCAGCGTCGGTGCCACCGAGACCTTGATGATGGCCGCTACGCTGGCGGATGGAGAAACGGTGA
TCGAGAACGCCGCCCAAGAGCCGGAGGTGGCGGATCTAGCCCGTTTTTGTCAAGCCATGGGGGCCCGCATTCGCGGTGTC
GGCACCAATACGGTTGTGGTGGTAGGGGTGCCCCGCTTGCATGGAACAGAGTACACGGTCATTCCCGACCGCATCGAGGC
CAGCACCTATCTCATTGCCGGGGCCATTACCCGCTCTCACCTCACGGTTGGCCCTGTTATTCCCGATCATCTGCGGGCGG
TGATCGCCAAGTTGCAAGCCATGGGTCTGCGGGTGGAAGAAGAGGGCCCAAACCGGTTGCGCATTGCCCCAGCTCAACTG
AGCTCAGGCTGGCTCTGTCAGGCAACCGATATTCAAACGCTGCCCTATCCCGGTTTCCCCACCGATGTGCAGGCGCCGAT
CATGGCTTTGGCCGCCTTGAGCGAGGGCAGTTGCACCATTGAGGAGACAGTGTTTGAAAACCGCATGCACCACATTCCCG
AGCTGAATCGCATGGGAGCCGATATTCGCCTGAAGAACCGAGTGGCCCTGATCCGAGGGGTGCCGTCCCTTTCCGGCGCT
CCGGTGGTGGCTACCGACCTGCGGGCGGGTGCGGCCCTGGTGTTGGCCGGTCTGGCGGCTGAAGGCTGCTCCACGATCCA
CGGATTGCACTACATCGACCGGGGCTACGAAGCCATTGATGAAAAGCTGCGCAGTGTCGGGGCCAAGGTGTACCGCAGCG
AAAGCCCGACAGGGATCCCGCAATTGGGGAAATGA

Upstream 100 bases:

>100_bases
TTCCTCACACCCAATTTGGCTTGCGAGTTTAGCCGCTGCTGTGATCCCCAGAGTATTCTCTGAGAAGGGTTCGCCTATTT
TTTGTGGGTGAGGAGGGAGA

Downstream 100 bases:

>100_bases
GCTGTTTCACTGCTGTCTGAAATTTGAAGATTTGAGGAAAGAACTGCTCCTCTCCCTGCTTATCGTCTGGCCCCAATGCT
CGGTGACCGCTTGCCAGGTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKGFDNRVSGADPLEPGLTPPQTGMATAPEMMGPVLKIIGKQTLSGHIPIGGAKNSALALMAGAILAPEACRIHNVPRLL
DIERMGQILATLGVKVSHVGNTLDLDASSLKTSQAPYELVSQLRASFFIIGPLLARLGVARVPLPGGCAIGSRPVDLHVR
GLQALGATVQIEHGVVHAYARKLLGTRIYLDYPSVGATETLMMAATLADGETVIENAAQEPEVADLARFCQAMGARIRGV
GTNTVVVVGVPRLHGTEYTVIPDRIEASTYLIAGAITRSHLTVGPVIPDHLRAVIAKLQAMGLRVEEEGPNRLRIAPAQL
SSGWLCQATDIQTLPYPGFPTDVQAPIMALAALSEGSCTIEETVFENRMHHIPELNRMGADIRLKNRVALIRGVPSLSGA
PVVATDLRAGAALVLAGLAAEGCSTIHGLHYIDRGYEAIDEKLRSVGAKVYRSESPTGIPQLGK

Sequences:

>Translated_464_residues
MKGFDNRVSGADPLEPGLTPPQTGMATAPEMMGPVLKIIGKQTLSGHIPIGGAKNSALALMAGAILAPEACRIHNVPRLL
DIERMGQILATLGVKVSHVGNTLDLDASSLKTSQAPYELVSQLRASFFIIGPLLARLGVARVPLPGGCAIGSRPVDLHVR
GLQALGATVQIEHGVVHAYARKLLGTRIYLDYPSVGATETLMMAATLADGETVIENAAQEPEVADLARFCQAMGARIRGV
GTNTVVVVGVPRLHGTEYTVIPDRIEASTYLIAGAITRSHLTVGPVIPDHLRAVIAKLQAMGLRVEEEGPNRLRIAPAQL
SSGWLCQATDIQTLPYPGFPTDVQAPIMALAALSEGSCTIEETVFENRMHHIPELNRMGADIRLKNRVALIRGVPSLSGA
PVVATDLRAGAALVLAGLAAEGCSTIHGLHYIDRGYEAIDEKLRSVGAKVYRSESPTGIPQLGK
>Mature_464_residues
MKGFDNRVSGADPLEPGLTPPQTGMATAPEMMGPVLKIIGKQTLSGHIPIGGAKNSALALMAGAILAPEACRIHNVPRLL
DIERMGQILATLGVKVSHVGNTLDLDASSLKTSQAPYELVSQLRASFFIIGPLLARLGVARVPLPGGCAIGSRPVDLHVR
GLQALGATVQIEHGVVHAYARKLLGTRIYLDYPSVGATETLMMAATLADGETVIENAAQEPEVADLARFCQAMGARIRGV
GTNTVVVVGVPRLHGTEYTVIPDRIEASTYLIAGAITRSHLTVGPVIPDHLRAVIAKLQAMGLRVEEEGPNRLRIAPAQL
SSGWLCQATDIQTLPYPGFPTDVQAPIMALAALSEGSCTIEETVFENRMHHIPELNRMGADIRLKNRVALIRGVPSLSGA
PVVATDLRAGAALVLAGLAAEGCSTIHGLHYIDRGYEAIDEKLRSVGAKVYRSESPTGIPQLGK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=426, Percent_Identity=45.7746478873239, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 48978; Mature: 48978

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFDNRVSGADPLEPGLTPPQTGMATAPEMMGPVLKIIGKQTLSGHIPIGGAKNSALAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MAGAILAPEACRIHNVPRLLDIERMGQILATLGVKVSHVGNTLDLDASSLKTSQAPYELV
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCEEECCCCEECCCHHHHCCCCCHHHHH
SQLRASFFIIGPLLARLGVARVPLPGGCAIGSRPVDLHVRGLQALGATVQIEHGVVHAYA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCEEEEECHHHHHHH
RKLLGTRIYLDYPSVGATETLMMAATLADGETVIENAAQEPEVADLARFCQAMGARIRGV
HHHHCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCEEEEC
GTNTVVVVGVPRLHGTEYTVIPDRIEASTYLIAGAITRSHLTVGPVIPDHLRAVIAKLQA
CCCEEEEEECCCCCCCEEEEECCCCCCCEEEEEEEHECCCEEECCCCHHHHHHHHHHHHH
MGLRVEEEGPNRLRIAPAQLSSGWLCQATDIQTLPYPGFPTDVQAPIMALAALSEGSCTI
HCCEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCH
EETVFENRMHHIPELNRMGADIRLKNRVALIRGVPSLSGAPVVATDLRAGAALVLAGLAA
HHHHHHHHHHCCCCHHHCCCCEEECCCEEEEECCCCCCCCCEEEECHHCCHHHHHHHHHH
EGCSTIHGLHYIDRGYEAIDEKLRSVGAKVYRSESPTGIPQLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKGFDNRVSGADPLEPGLTPPQTGMATAPEMMGPVLKIIGKQTLSGHIPIGGAKNSALAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MAGAILAPEACRIHNVPRLLDIERMGQILATLGVKVSHVGNTLDLDASSLKTSQAPYELV
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCEEECCCCEECCCHHHHCCCCCHHHHH
SQLRASFFIIGPLLARLGVARVPLPGGCAIGSRPVDLHVRGLQALGATVQIEHGVVHAYA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCEEEEECHHHHHHH
RKLLGTRIYLDYPSVGATETLMMAATLADGETVIENAAQEPEVADLARFCQAMGARIRGV
HHHHCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCEEEEC
GTNTVVVVGVPRLHGTEYTVIPDRIEASTYLIAGAITRSHLTVGPVIPDHLRAVIAKLQA
CCCEEEEEECCCCCCCEEEEECCCCCCCEEEEEEEHECCCEEECCCCHHHHHHHHHHHHH
MGLRVEEEGPNRLRIAPAQLSSGWLCQATDIQTLPYPGFPTDVQAPIMALAALSEGSCTI
HCCEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCH
EETVFENRMHHIPELNRMGADIRLKNRVALIRGVPSLSGAPVVATDLRAGAALVLAGLAA
HHHHHHHHHHCCCCHHHCCCCEEECCCEEEEECCCCCCCCCEEEECHHCCHHHHHHHHHH
EGCSTIHGLHYIDRGYEAIDEKLRSVGAKVYRSESPTGIPQLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]