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The map label for this gene is lysN [H]

Identifier: 86606364

GI number: 86606364

Start: 1717994

End: 1719319

Strand: Reverse

Name: lysN [H]

Synonym: CYA_1709

Alternate gene names: 86606364

Gene position: 1719319-1717994 (Counterclockwise)

Preceding gene: 86606365

Following gene: 86606360

Centisome position: 58.62

GC content: 63.05

Gene sequence:

>1326_bases
TTGGCCCTGGGCGGAACGCCAACAAACCCTGCTCAGCTTGGCTGGTTTGGGCCATGTCCTGTGGATGGGGGTGCTAGCAG
CTTGGCTTTGGGATCCCCAGATGAACCTGTTGCAGCAAAGCGCCCGTTGGGGCCTGGTGGCCCTGCCCTTTTTGTGCCTG
AGTGCCGGTGGCGTCTTGGCGGAGATCCCCTGCCGGGGCTGGCGACAGTTTTTGGGATCCCTGCTCTTAGCCAGCTCGTT
CTTGTTATCGTGGCAAGCGTTGGCCTGAGTTCTTCTCCTGCCTTGAAGATTCGGATGCGGCCCCTCTTAGAGACCCTGTT
CGCCCGGCGGGCCCAGGCGGTGATCCCGCCTCCTGTTGGCGCGGAGATCGCTGGGGCGGTGCCGGTAGTAACCAGTTTTA
CCTTTGGCCTGGCGGATCCGCGGTTGTTTCCCAAGGCCGACCTGGCGCGGGCGACAGCGGAGGTGTTGGCGGAAGATGGG
GATGCTGCCCTCAATTACGGCGGCACCTTTGCCGGGTTGATCGAGGTGGTGCAGCAGTTGATGCGGGCCAGAGGGGTGGA
GGCGCAGCCGGAAAACCTCTTGATCGGCTATGGCTCTGGGCAGATCCTTGGCCTCTTGCCCCAGGTCTTTGTGGAGCCGG
GGGATGTGGTGATCGTGGAGGGGCCCACCTTCATGGGGGCGGTCAGCCGTTTTGCGGCGGCAGGGGCGCGTCTGATCTCG
ATCCCGGTGGATGGGGAGGGCATGGTGGTGGATCGCCTGGAAGAGGTGTTGCGCGAGCTAGCCCGCCAAGGGATCCCACC
CCGCTTTATCTACACCATTCCCACCTTTCACAACCCTAGGGGCTGCACCCTCTCTTGGCCGCGGCGGCAGAAGCTGCTGC
AGTTGGCGGCTGAATACGGCGTGGTGGTGGTGGAGGACGAGGCCTACTACGACCTGCGCTTTGTCGGGGATCCCTTGCCC
AGTTTGGCCGCGCTGGATAAAGAGGGCTGGGTTCTGCACGTGGGCACCTTTTCCAAGATTGTGGCGCCGGGGGTGCGGGT
GGGCTGGGCCTGTGGCCATCCCGAGATCATCCGCCGCTTGGAGATGTTTCGCAGCGAGGGATCCCTGGGGCCTTTTTTGG
GCCGGGTGGTGGCCCGATACTGCGGGGAAGGCCGCCTAGAGAGCCACATTCAGCTTTTGATCCGCCGTTACCGAGAAAAG
TGCCACCTGATGTTGGAGGCCATCGCTCAATGTTTTCCCCCTGAAGTCAAGGTGGAGGCCCCTGGGGGTGGATTCTTTAT
CTGGTGCGAGCTGCCCCCTCCCCTGAGTGCCAACACCTTGCTGTAG

Upstream 100 bases:

>100_bases
TTCCTACGGCGACGGTGTCCTATTCGCTCACCAGCCAAAGCGGCCTGGCTGTTCTGGCCACCTTGATGTTGCCCTTGGGG
CTGGCCTTGGTGCGGCTGGG

Downstream 100 bases:

>100_bases
GCCACCCGAGCGCTGGGGGTAACTTTCTTGCCGGGTACCCACTGCTTTGCTGATGGCCAAGGGGATCACGCCCTGCGCCT
CGCCTTCAGCTACCAACCGG

Product: aminotransferase, classes I and II

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MALGGTPTNPAQLGWFGPCPVDGGASSLALGSPDEPVAAKRPLGPGGPALFVPECRWRLGGDPLPGLATVFGIPALSQLV
LVIVASVGLSSSPALKIRMRPLLETLFARRAQAVIPPPVGAEIAGAVPVVTSFTFGLADPRLFPKADLARATAEVLAEDG
DAALNYGGTFAGLIEVVQQLMRARGVEAQPENLLIGYGSGQILGLLPQVFVEPGDVVIVEGPTFMGAVSRFAAAGARLIS
IPVDGEGMVVDRLEEVLRELARQGIPPRFIYTIPTFHNPRGCTLSWPRRQKLLQLAAEYGVVVVEDEAYYDLRFVGDPLP
SLAALDKEGWVLHVGTFSKIVAPGVRVGWACGHPEIIRRLEMFRSEGSLGPFLGRVVARYCGEGRLESHIQLLIRRYREK
CHLMLEAIAQCFPPEVKVEAPGGGFFIWCELPPPLSANTLL

Sequences:

>Translated_441_residues
MALGGTPTNPAQLGWFGPCPVDGGASSLALGSPDEPVAAKRPLGPGGPALFVPECRWRLGGDPLPGLATVFGIPALSQLV
LVIVASVGLSSSPALKIRMRPLLETLFARRAQAVIPPPVGAEIAGAVPVVTSFTFGLADPRLFPKADLARATAEVLAEDG
DAALNYGGTFAGLIEVVQQLMRARGVEAQPENLLIGYGSGQILGLLPQVFVEPGDVVIVEGPTFMGAVSRFAAAGARLIS
IPVDGEGMVVDRLEEVLRELARQGIPPRFIYTIPTFHNPRGCTLSWPRRQKLLQLAAEYGVVVVEDEAYYDLRFVGDPLP
SLAALDKEGWVLHVGTFSKIVAPGVRVGWACGHPEIIRRLEMFRSEGSLGPFLGRVVARYCGEGRLESHIQLLIRRYREK
CHLMLEAIAQCFPPEVKVEAPGGGFFIWCELPPPLSANTLL
>Mature_440_residues
ALGGTPTNPAQLGWFGPCPVDGGASSLALGSPDEPVAAKRPLGPGGPALFVPECRWRLGGDPLPGLATVFGIPALSQLVL
VIVASVGLSSSPALKIRMRPLLETLFARRAQAVIPPPVGAEIAGAVPVVTSFTFGLADPRLFPKADLARATAEVLAEDGD
AALNYGGTFAGLIEVVQQLMRARGVEAQPENLLIGYGSGQILGLLPQVFVEPGDVVIVEGPTFMGAVSRFAAAGARLISI
PVDGEGMVVDRLEEVLRELARQGIPPRFIYTIPTFHNPRGCTLSWPRRQKLLQLAAEYGVVVVEDEAYYDLRFVGDPLPS
LAALDKEGWVLHVGTFSKIVAPGVRVGWACGHPEIIRRLEMFRSEGSLGPFLGRVVARYCGEGRLESHIQLLIRRYREKC
HLMLEAIAQCFPPEVKVEAPGGGFFIWCELPPPLSANTLL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=329, Percent_Identity=25.8358662613982, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI33469970, Length=329, Percent_Identity=25.8358662613982, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1787710, Length=324, Percent_Identity=32.4074074074074, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1790797, Length=291, Percent_Identity=30.2405498281787, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788722, Length=255, Percent_Identity=24.3137254901961, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=175, Percent_Identity=31.4285714285714, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321929, Length=203, Percent_Identity=26.1083743842365, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356535, Length=301, Percent_Identity=26.2458471760797, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 47095; Mature: 46964

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALGGTPTNPAQLGWFGPCPVDGGASSLALGSPDEPVAAKRPLGPGGPALFVPECRWRLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHCCC
GDPLPGLATVFGIPALSQLVLVIVASVGLSSSPALKIRMRPLLETLFARRAQAVIPPPVG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCC
AEIAGAVPVVTSFTFGLADPRLFPKADLARATAEVLAEDGDAALNYGGTFAGLIEVVQQL
CHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHH
MRARGVEAQPENLLIGYGSGQILGLLPQVFVEPGDVVIVEGPTFMGAVSRFAAAGARLIS
HHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCEEEE
IPVDGEGMVVDRLEEVLRELARQGIPPRFIYTIPTFHNPRGCTLSWPRRQKLLQLAAEYG
EEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCC
VVVVEDEAYYDLRFVGDPLPSLAALDKEGWVLHVGTFSKIVAPGVRVGWACGHPEIIRRL
EEEEECCCEEEEEECCCCCCHHHHCCCCCCEEEECCHHHHHCCCCEEEECCCCHHHHHHH
EMFRSEGSLGPFLGRVVARYCGEGRLESHIQLLIRRYREKCHLMLEAIAQCFPPEVKVEA
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
PGGGFFIWCELPPPLSANTLL
CCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ALGGTPTNPAQLGWFGPCPVDGGASSLALGSPDEPVAAKRPLGPGGPALFVPECRWRLG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHCCC
GDPLPGLATVFGIPALSQLVLVIVASVGLSSSPALKIRMRPLLETLFARRAQAVIPPPVG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCC
AEIAGAVPVVTSFTFGLADPRLFPKADLARATAEVLAEDGDAALNYGGTFAGLIEVVQQL
CHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHH
MRARGVEAQPENLLIGYGSGQILGLLPQVFVEPGDVVIVEGPTFMGAVSRFAAAGARLIS
HHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCEEEE
IPVDGEGMVVDRLEEVLRELARQGIPPRFIYTIPTFHNPRGCTLSWPRRQKLLQLAAEYG
EEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCC
VVVVEDEAYYDLRFVGDPLPSLAALDKEGWVLHVGTFSKIVAPGVRVGWACGHPEIIRRL
EEEEECCCEEEEEECCCCCCHHHHCCCCCCEEEECCHHHHHCCCCEEEECCCCHHHHHHH
EMFRSEGSLGPFLGRVVARYCGEGRLESHIQLLIRRYREKCHLMLEAIAQCFPPEVKVEA
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
PGGGFFIWCELPPPLSANTLL
CCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA