Click here to switch to the map view.

The map label for this gene is trpS

Identifier: 86606016

GI number: 86606016

Start: 1353066

End: 1354061

Strand: Reverse

Name: trpS

Synonym: CYA_1340

Alternate gene names: 86606016

Gene position: 1354061-1353066 (Counterclockwise)

Preceding gene: 86606020

Following gene: 86606014

Centisome position: 46.17

GC content: 59.44

Gene sequence:

>996_bases
ATGGCCAAGCCGCGCACGCTTTCTGGAATCCAGCCCTCCGGCGAGTTGCACCTGGGCAATTACTTGGGGGCCATTAAAAA
CTGGGTGGCCGAGCAGGAGCGCTACGAGAACTTCTTCTGCATTGTGGATCAACATGCCATTACTGTGCCCCAGGATCCCA
AGCTGCTGAGGGAGCGCACCCGTTCTTTGTTTGCTCTCTACCTGGCCTGTGGCCTCAGCCTGGAGCACTGTGTGCTGTTT
GTGCAGTCCCACGTGCCCGCCCACACGGAGCTGGCCTGGCTGTTCACCACCATCACCCCTATGAACTGGGCGGAGCGCAT
GATCCAGTACAAGGAAAAAAAAGAGAAGCAGGGAGAGGAAACGAGTGTTGGCCTGTTCAGCTACCCGATTTTGCAGGCAG
CGGATATTCTCCTCTACCAGCCCAAGTATGTGCCGGTAGGGGAGGATCAGCGGCAGCACATCGAGCTGTGTCGGGACATT
GCCCGCCGCTTTAACGACCGCTTTGGGGAGGTGTTTGTGATCCCAGAGGCGCTGATTCGCCCGCAGGGGGCGCGGATCAT
GAGCTTGACCGATGGCACCCGCAAAATGTCTAAGTCGGATCCCTCGGATTTCAGCCGCATTCACTTGCTAGACGACCCCG
ACACGATCCGCAAGAAGATCCAAAAATGCAAGACCGACTCGATTCGGGGCATTGCCTTCGACGACCCGGCACGCCCGGAG
GCCCACAATTTGCTGACGATCTACATGCTCACCTCCGGCAAAAGCAAGGAGGAGGTGGCGGCTGAGTGCGCCGAGATGGG
ATGGGGACAGTTCAAGCCCCTCCTCGCCGACAGCATTATCGCCACCCTGGAGCCCATTCAAAAGCGCTACCGGGAGCTCT
CGAGTGACCCCGACTACCTCCACGGGCTGATGCGGGAAAATGCCGCCAAGGCCCGTGCCGTGGCCGAGCAAACCCTCCAA
AAAGCGCGGGATGCCATGGGGTTTCTGCCCCCCTAG

Upstream 100 bases:

>100_bases
TCCCTCATAAACCAACGGGTTGCGGCTCTCTTGATATCCTGAACAAAGACTTTCTTGGTTCTCGTCCTCCCTCTTGTTGG
CGTTTGAGATCGCTTTTCCT

Downstream 100 bases:

>100_bases
GAGAAGGCTCCCTTAGTCGGGTCGGCCATCGCGGATCTCGACGGTGCTGAACTCCAGGCCCAGCTCCGAGAGGATCCCTG
GCCAGGCCAGGCGCAGGCGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAKPRTLSGIQPSGELHLGNYLGAIKNWVAEQERYENFFCIVDQHAITVPQDPKLLRERTRSLFALYLACGLSLEHCVLF
VQSHVPAHTELAWLFTTITPMNWAERMIQYKEKKEKQGEETSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDI
ARRFNDRFGEVFVIPEALIRPQGARIMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDSIRGIAFDDPARPE
AHNLLTIYMLTSGKSKEEVAAECAEMGWGQFKPLLADSIIATLEPIQKRYRELSSDPDYLHGLMRENAAKARAVAEQTLQ
KARDAMGFLPP

Sequences:

>Translated_331_residues
MAKPRTLSGIQPSGELHLGNYLGAIKNWVAEQERYENFFCIVDQHAITVPQDPKLLRERTRSLFALYLACGLSLEHCVLF
VQSHVPAHTELAWLFTTITPMNWAERMIQYKEKKEKQGEETSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDI
ARRFNDRFGEVFVIPEALIRPQGARIMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDSIRGIAFDDPARPE
AHNLLTIYMLTSGKSKEEVAAECAEMGWGQFKPLLADSIIATLEPIQKRYRELSSDPDYLHGLMRENAAKARAVAEQTLQ
KARDAMGFLPP
>Mature_330_residues
AKPRTLSGIQPSGELHLGNYLGAIKNWVAEQERYENFFCIVDQHAITVPQDPKLLRERTRSLFALYLACGLSLEHCVLFV
QSHVPAHTELAWLFTTITPMNWAERMIQYKEKKEKQGEETSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDIA
RRFNDRFGEVFVIPEALIRPQGARIMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDSIRGIAFDDPARPEA
HNLLTIYMLTSGKSKEEVAAECAEMGWGQFKPLLADSIIATLEPIQKRYRELSSDPDYLHGLMRENAAKARAVAEQTLQK
ARDAMGFLPP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=40.7294832826748, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=49.7206703910614, Blast_Score=195, Evalue=4e-50,
Organism=Escherichia coli, GI1789786, Length=331, Percent_Identity=45.619335347432, Blast_Score=300, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=36.5558912386707, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=36.0606060606061, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320474, Length=343, Percent_Identity=37.9008746355685, Blast_Score=216, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24666151, Length=326, Percent_Identity=39.2638036809816, Blast_Score=242, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37674; Mature: 37543

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPRTLSGIQPSGELHLGNYLGAIKNWVAEQERYENFFCIVDQHAITVPQDPKLLRERT
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCEEECCCCHHHHHHHH
RSLFALYLACGLSLEHCVLFVQSHVPAHTELAWLFTTITPMNWAERMIQYKEKKEKQGEE
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
TSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDIARRFNDRFGEVFVIPEALIR
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHC
PQGARIMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDSIRGIAFDDPARPE
CCCCEEEEECCHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEECCCCCCCC
AHNLLTIYMLTSGKSKEEVAAECAEMGWGQFKPLLADSIIATLEPIQKRYRELSSDPDYL
CCCEEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HGLMRENAAKARAVAEQTLQKARDAMGFLPP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKPRTLSGIQPSGELHLGNYLGAIKNWVAEQERYENFFCIVDQHAITVPQDPKLLRERT
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCEEECCCCHHHHHHHH
RSLFALYLACGLSLEHCVLFVQSHVPAHTELAWLFTTITPMNWAERMIQYKEKKEKQGEE
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
TSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDIARRFNDRFGEVFVIPEALIR
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHC
PQGARIMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDSIRGIAFDDPARPE
CCCCEEEEECCHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEECCCCCCCC
AHNLLTIYMLTSGKSKEEVAAECAEMGWGQFKPLLADSIIATLEPIQKRYRELSSDPDYL
CCCEEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HGLMRENAAKARAVAEQTLQKARDAMGFLPP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]