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The map label for this gene is tynA

Identifier: 86606020

GI number: 86606020

Start: 1356160

End: 1358178

Strand: Reverse

Name: tynA

Synonym: CYA_1346

Alternate gene names: 86606020

Gene position: 1358178-1356160 (Counterclockwise)

Preceding gene: 86606021

Following gene: 86606016

Centisome position: 46.31

GC content: 62.36

Gene sequence:

>2019_bases
GTGATTTGTGAACTTCCGCGAAGTCCTCAGTCTGCTCCGCACGATTCGGAGCGCTATCGACATCGCCCGTCGAGGGGCTC
TGCTTCCCGGCTGGAGTGGCCCAGCCACCCTCTGGATCCCCTAAATGGCGAAGAAATCCGGGAAGTGGTCAAAATCCTGC
GTCAGGAGCGCCCTCTTGCTTCCCGCTGCCGCTTCGTCACCATCCAACTGCAGGAGCCGGAGCGGCCTTGGATGGAAGCG
TGGCAGCCGGGCCAGCCCTGGGATCGGCAGGCGTTTGCGGTGCTGTTGGATCCCGCCGAGGGCAGCACGTATGAGGCGGT
GGTCTCCCTCTCCCGGCAGCAGGTGTGCTCTTGGCAGCTCGTCCCCGGCATGCAGCCGCCCCTTTTGGACGATGAGGTGT
ACGCCTGCGACCGCCTGCTCAAGGCGGATCCCCAATTCCTGGCCGCCCTGCAGCGGCGGGGCATTGCCGATGTGGAGCGG
GTGATGGTGGACTACTGGACGGTGGGCTACTTTGGGATCCCGGAAGAAGAGGGGCGGCGTCTGGTGCGGGGCCTGTGTTT
CCTGCGCACTTCTCCTTACGACAATGGCTATGCCCGTCCCATCGAGGGCCTCTACCCCTGGATCGACCTCAACCAAATGC
AGGTCGTCAAGGTGGAGGATCGCGGCCCCTGGCCTCTGCCCCCGGAAGATGGCAATTTCGACGAGATCTTCTTCAAAGAG
TTTCGCCAAGATTTGAAGCCTTTGGAAATTACCCAGCCCCAAGGGGTGAGCTTCCAGGTGGAAGGCCATCACATCCGCTG
GCAGAAGTGGGATCTGCGCATCAGCTTTAACCCCCGCGAGGGGCTGGTGCTGCATCAGGTGGGCTATGAGGATCAGGGCC
GGCTTCGTCCTATCCTCTACCGCGCTTCGGTAGCCGAGATGGTGGTGCCCTACGGCGATCCCCGCGATCCCCACTGCCGC
AAGAACGCCTTTGACGTGGGGGAATACGGCATCGGCATGCAGGCCAATTCCCTGCGCCTGGGCTGCGACTGCCTGGGGGA
GATCTACTACTTCGATGCCTGGCTGCCCAGCAACAGCGGCGAGCCCATGCTCCTCAAAAACGCCATCTGCATGCACGAAG
AAGACTTCGGCGTGCTCTGGAAGCACACCGACTGGCGCACGGAGCGAGCCCAGGTGCGGCGCTCGCGGCGGCTGGTGCTC
TCTTTCTTTACCACCATCGGCAACTACGACTACGGCTTTTTCTGGTACTTTTACCAGGATGGCACCCTGGAGTTCGAGGC
CAAGCTCACCGGCATTATCAACACCTGCGCCACCCTGCCGGGGGAGGAGCCGGAATTTGGCGTCTTGGTGGCGCCGCAGC
TCTCTGGTCTCAACCACCAGCACTTTTTCACCGTTCGCCTGGACATGGCGGTGGATGGGCCGGGCAACTCCCTCTACGAA
GTGCATGCCGAGCCGCTGCCGCCGGGGCCGGATAACCCCTACGGAAACGCCTTCCGCGCCCGCTCCACCCTGCTCAAAAC
CGAGCAGGAAGCTAAGCAAACGGTGGATCCCTTGCGGGGGCGCTACTGGAAGATTGTCAACCCCAACCGCCACAATCGCC
TGGGGCAGCCGGTGGCCTACAAACTGATGCCGGGGGAAAACGTCCAGCTTTTGGCCCACCCCGACTCTTGGCTGTACCGA
CGGGCAGGATACCTGGCCCACCACCTCTGGGCCACGCCCTACCATCCCGGCGAGAAGTTCCCAGCAGGGAACTACCCCAA
CCAACATCCCGGTGGCGAAGGGCTGGTGCAATGGACGCAAGCGAACCGCTCCCTGGAAAACACCCGCCTGGTGCTCTGGT
ATAGCTTTGGCTGCAATCACTTCCCCCGCACCGAGGACTGGCCAGTGATGCCGGTTAGCTACATCGGCTTTATGCTCAAG
CCCCTGGGCTTCTTTGAGTGCAACCCGGCTTTGGATGTGCCCCCGCCTCCGCCAAAGATCAAAGGCTGCTGCAGCTTGAG
TCATTCCAACCAGCAGTGA

Upstream 100 bases:

>100_bases
CTCAGAACACCTGCGCTGGCGGGCAGGGGGATCCCTGCGGCATTTTTCAACGGATCGTCACCCAGTCAATCCATTTTCTG
TAGAATTCAAGGTTATTTCT

Downstream 100 bases:

>100_bases
GCGCCATATCCACCCCCTGTCCCTCATCGCGCTGACCGAATCGGGATCCAACGGATTTGGGTGGGCTGTCAAGAATATCA
AAAAGCCCAGAAGCCTTGCT

Product: tyramine oxidase

Products: NA

Alternate protein names: Copper amine oxidase; MAOXI [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MICELPRSPQSAPHDSERYRHRPSRGSASRLEWPSHPLDPLNGEEIREVVKILRQERPLASRCRFVTIQLQEPERPWMEA
WQPGQPWDRQAFAVLLDPAEGSTYEAVVSLSRQQVCSWQLVPGMQPPLLDDEVYACDRLLKADPQFLAALQRRGIADVER
VMVDYWTVGYFGIPEEEGRRLVRGLCFLRTSPYDNGYARPIEGLYPWIDLNQMQVVKVEDRGPWPLPPEDGNFDEIFFKE
FRQDLKPLEITQPQGVSFQVEGHHIRWQKWDLRISFNPREGLVLHQVGYEDQGRLRPILYRASVAEMVVPYGDPRDPHCR
KNAFDVGEYGIGMQANSLRLGCDCLGEIYYFDAWLPSNSGEPMLLKNAICMHEEDFGVLWKHTDWRTERAQVRRSRRLVL
SFFTTIGNYDYGFFWYFYQDGTLEFEAKLTGIINTCATLPGEEPEFGVLVAPQLSGLNHQHFFTVRLDMAVDGPGNSLYE
VHAEPLPPGPDNPYGNAFRARSTLLKTEQEAKQTVDPLRGRYWKIVNPNRHNRLGQPVAYKLMPGENVQLLAHPDSWLYR
RAGYLAHHLWATPYHPGEKFPAGNYPNQHPGGEGLVQWTQANRSLENTRLVLWYSFGCNHFPRTEDWPVMPVSYIGFMLK
PLGFFECNPALDVPPPPPKIKGCCSLSHSNQQ

Sequences:

>Translated_672_residues
MICELPRSPQSAPHDSERYRHRPSRGSASRLEWPSHPLDPLNGEEIREVVKILRQERPLASRCRFVTIQLQEPERPWMEA
WQPGQPWDRQAFAVLLDPAEGSTYEAVVSLSRQQVCSWQLVPGMQPPLLDDEVYACDRLLKADPQFLAALQRRGIADVER
VMVDYWTVGYFGIPEEEGRRLVRGLCFLRTSPYDNGYARPIEGLYPWIDLNQMQVVKVEDRGPWPLPPEDGNFDEIFFKE
FRQDLKPLEITQPQGVSFQVEGHHIRWQKWDLRISFNPREGLVLHQVGYEDQGRLRPILYRASVAEMVVPYGDPRDPHCR
KNAFDVGEYGIGMQANSLRLGCDCLGEIYYFDAWLPSNSGEPMLLKNAICMHEEDFGVLWKHTDWRTERAQVRRSRRLVL
SFFTTIGNYDYGFFWYFYQDGTLEFEAKLTGIINTCATLPGEEPEFGVLVAPQLSGLNHQHFFTVRLDMAVDGPGNSLYE
VHAEPLPPGPDNPYGNAFRARSTLLKTEQEAKQTVDPLRGRYWKIVNPNRHNRLGQPVAYKLMPGENVQLLAHPDSWLYR
RAGYLAHHLWATPYHPGEKFPAGNYPNQHPGGEGLVQWTQANRSLENTRLVLWYSFGCNHFPRTEDWPVMPVSYIGFMLK
PLGFFECNPALDVPPPPPKIKGCCSLSHSNQQ
>Mature_672_residues
MICELPRSPQSAPHDSERYRHRPSRGSASRLEWPSHPLDPLNGEEIREVVKILRQERPLASRCRFVTIQLQEPERPWMEA
WQPGQPWDRQAFAVLLDPAEGSTYEAVVSLSRQQVCSWQLVPGMQPPLLDDEVYACDRLLKADPQFLAALQRRGIADVER
VMVDYWTVGYFGIPEEEGRRLVRGLCFLRTSPYDNGYARPIEGLYPWIDLNQMQVVKVEDRGPWPLPPEDGNFDEIFFKE
FRQDLKPLEITQPQGVSFQVEGHHIRWQKWDLRISFNPREGLVLHQVGYEDQGRLRPILYRASVAEMVVPYGDPRDPHCR
KNAFDVGEYGIGMQANSLRLGCDCLGEIYYFDAWLPSNSGEPMLLKNAICMHEEDFGVLWKHTDWRTERAQVRRSRRLVL
SFFTTIGNYDYGFFWYFYQDGTLEFEAKLTGIINTCATLPGEEPEFGVLVAPQLSGLNHQHFFTVRLDMAVDGPGNSLYE
VHAEPLPPGPDNPYGNAFRARSTLLKTEQEAKQTVDPLRGRYWKIVNPNRHNRLGQPVAYKLMPGENVQLLAHPDSWLYR
RAGYLAHHLWATPYHPGEKFPAGNYPNQHPGGEGLVQWTQANRSLENTRLVLWYSFGCNHFPRTEDWPVMPVSYIGFMLK
PLGFFECNPALDVPPPPPKIKGCCSLSHSNQQ

Specific function: The exact function of maoXI is not known [H]

COG id: COG3733

COG function: function code Q; Cu2+-containing amine oxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the copper/topaquinone oxidase family [H]

Homologues:

Organism=Homo sapiens, GI73486661, Length=417, Percent_Identity=25.8992805755396, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI60498984, Length=455, Percent_Identity=26.5934065934066, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI60498982, Length=452, Percent_Identity=26.5486725663717, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI4502119, Length=413, Percent_Identity=24.455205811138, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1787651, Length=637, Percent_Identity=32.4960753532182, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000269
- InterPro:   IPR015798
- InterPro:   IPR016182
- InterPro:   IPR015800
- InterPro:   IPR015801
- InterPro:   IPR015802 [H]

Pfam domain/function: PF01179 Cu_amine_oxid; PF02727 Cu_amine_oxidN2; PF02728 Cu_amine_oxidN3 [H]

EC number: =1.4.3.21 [H]

Molecular weight: Translated: 77341; Mature: 77341

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01164 COPPER_AMINE_OXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICELPRSPQSAPHDSERYRHRPSRGSASRLEWPSHPLDPLNGEEIREVVKILRQERPLA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHH
SRCRFVTIQLQEPERPWMEAWQPGQPWDRQAFAVLLDPAEGSTYEAVVSLSRQQVCSWQL
HCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCEEEE
VPGMQPPLLDDEVYACDRLLKADPQFLAALQRRGIADVERVMVDYWTVGYFGIPEEEGRR
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCEECCCHHHHHH
LVRGLCFLRTSPYDNGYARPIEGLYPWIDLNQMQVVKVEDRGPWPLPPEDGNFDEIFFKE
HHHHHHHEECCCCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
FRQDLKPLEITQPQGVSFQVEGHHIRWQKWDLRISFNPREGLVLHQVGYEDQGRLRPILY
HHHCCCCEEECCCCCCEEEECCCEEEEEEEEEEEEECCCCCEEEEECCCCCCCCCEEEEE
RASVAEMVVPYGDPRDPHCRKNAFDVGEYGIGMQANSLRLGCDCLGEIYYFDAWLPSNSG
HHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHCCEEEEEEECCCCCC
EPMLLKNAICMHEEDFGVLWKHTDWRTERAQVRRSRRLVLSFFTTIGNYDYGFFWYFYQD
CCEEEECEEHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GTLEFEAKLTGIINTCATLPGEEPEFGVLVAPQLSGLNHQHFFTVRLDMAVDGPGNSLYE
CCEEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCCEEE
VHAEPLPPGPDNPYGNAFRARSTLLKTEQEAKQTVDPLRGRYWKIVNPNRHNRLGQPVAY
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEE
KLMPGENVQLLAHPDSWLYRRAGYLAHHLWATPYHPGEKFPAGNYPNQHPGGEGLVQWTQ
EECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEH
ANRSLENTRLVLWYSFGCNHFPRTEDWPVMPVSYIGFMLKPLGFFECNPALDVPPPPPKI
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCC
KGCCSLSHSNQQ
CCEEECCCCCCC
>Mature Secondary Structure
MICELPRSPQSAPHDSERYRHRPSRGSASRLEWPSHPLDPLNGEEIREVVKILRQERPLA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHH
SRCRFVTIQLQEPERPWMEAWQPGQPWDRQAFAVLLDPAEGSTYEAVVSLSRQQVCSWQL
HCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCEEEE
VPGMQPPLLDDEVYACDRLLKADPQFLAALQRRGIADVERVMVDYWTVGYFGIPEEEGRR
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCEECCCHHHHHH
LVRGLCFLRTSPYDNGYARPIEGLYPWIDLNQMQVVKVEDRGPWPLPPEDGNFDEIFFKE
HHHHHHHEECCCCCCCCCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
FRQDLKPLEITQPQGVSFQVEGHHIRWQKWDLRISFNPREGLVLHQVGYEDQGRLRPILY
HHHCCCCEEECCCCCCEEEECCCEEEEEEEEEEEEECCCCCEEEEECCCCCCCCCEEEEE
RASVAEMVVPYGDPRDPHCRKNAFDVGEYGIGMQANSLRLGCDCLGEIYYFDAWLPSNSG
HHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHCCEEEEEEECCCCCC
EPMLLKNAICMHEEDFGVLWKHTDWRTERAQVRRSRRLVLSFFTTIGNYDYGFFWYFYQD
CCEEEECEEHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GTLEFEAKLTGIINTCATLPGEEPEFGVLVAPQLSGLNHQHFFTVRLDMAVDGPGNSLYE
CCEEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCCEEE
VHAEPLPPGPDNPYGNAFRARSTLLKTEQEAKQTVDPLRGRYWKIVNPNRHNRLGQPVAY
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEE
KLMPGENVQLLAHPDSWLYRRAGYLAHHLWATPYHPGEKFPAGNYPNQHPGGEGLVQWTQ
EECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEH
ANRSLENTRLVLWYSFGCNHFPRTEDWPVMPVSYIGFMLKPLGFFECNPALDVPPPPPKI
HCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCC
KGCCSLSHSNQQ
CCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8366046 [H]