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The map label for this gene is dnaX

Identifier: 86605279

GI number: 86605279

Start: 575990

End: 578068

Strand: Reverse

Name: dnaX

Synonym: CYA_0563

Alternate gene names: 86605279

Gene position: 578068-575990 (Counterclockwise)

Preceding gene: 86605280

Following gene: 86605277

Centisome position: 19.71

GC content: 63.92

Gene sequence:

>2079_bases
ATGGCCGTTGCTGGCAAGTACGAACCCCTTCATTTGAAATACCGCCCGCAGCGCTTTGCCGAGGTGGTGGGCCAAGGGGC
AGTCGTGCAGACTTTGGCCAATGCCATCCGGCTGGGGCGGGTGGCGCCGGCCTACTTGTTCTGTGGGCCGCGGGGCACCG
GAAAAACCTCCAGCGCCCGCATCTTGGCCAAGTCTTTAAATTGCGAGCAGGGGCCAACGCCGGATCCCTGTCAGGTATGC
AGCCAGTGCCGCGCCATCACCGCCGGCTCTTCTTTGGACGTGATTGAGATCGACGCGGCCAGCAACACCGGCGTAGACAA
CATCCGCGAGCTGATCGAGCGGGCCCAATTTGCGCCGGTAAATAGCCGCTACAAGGTCTATGTCATCGACGAGTGCCACA
TGCTCAGCAATGCCGCCTTCAACGCGTTGCTGAAGACGCTGGAAGAGCCGCCTCCTCGCGTGGTGTTTGTGCTGGCCACC
ACCGACCCCCAGCGGGTTCTGCCCACCATCGTTTCCCGCTGTCAGCGGTTTGACTTCCGCCGCATCCCCCTTGACGACAT
GGTGGCCCACCTGGGCCAGATCGCCGCCCAGGAAGGGATCCCCATTGCACCAGAAGCCTTGCACCTGGTGGCCCAACTGG
CCCAGGGCGGGCTGCGGGACGCCGAGCGCCTGTTGGATCAGCTCAGCTTGCTGGAGGGATCCATCACCCCAGAAGCCGTA
TGGGACTTGGTGGGCGGGATCCCGGAGCGGCAGCTTTTGGATTTGACCGATGCGTTGCTGGCTCAGGATGTGCAGGCGGT
GCTGGCCCAGACGCGACAATTGCTGGAGCGGGGCAGAGAGCCCCTGGTGGTGCTGCAGAGCCTGGTGGTTTTTTACCGGG
ATCTGCTGCTGGCCAAGACGGCCCCCCAACAGCGGCAGTTGGCGGCCGTAACGGATCCCACCTGGGCAGCTCTGCAGCAG
CGGGCTCCTCGCTACTCGGTGGAGATGCTGCTGGCGGCCCAGAGCCACCTGCGCCAGTGCGAGCCGCAAATTCGCCAGAG
CGGGCAACCCCAGCTTTGGTTGGAGATCGCCCTGCTGGATCTGCTGGGCCAGCTTCGCCAGAGTGCCGTCCCGCTGCCGT
CAATAGAGGCCAAAGGCGGAGAGCCGCTCCCAGCCGTCGGCCCGCCAACGGTCGGAAAGACCCCTAGCCCCACCGTCCCA
GCCAGCGAGGAGCTGACAGCTCCTACGACAACCCTTCCAGAGACCCCAGCCCCTTCCCCTGCTGCAACAGGGGGATCCCT
CCCGCCGTCGCAAACGGCAAAGCCAAGTCGGGAGAAGCCGGCCAGCCCGGAAAAAGCGAAAGATCCGCATCCCCTCAAGC
TGCTGCGGCCCCGGTGGGAGGAGTTTCTTGAAAACCTTCGCCCCATCACCAGAGGCCTATTGGCATCCGGCTATTTGCAG
CAGGAGTCTCTCGTTGGCTCTGACGGGACGGAGACCTTAGAGATCACCCTTGCTTTTCCCAATAAGGGCTTAGTGGACAA
GGTGCGCAGCAAAGAAGCCGAGCTCTGCTCTGCGCTCCACAACCTGCTGCAGCGCCCGGTGCGGCTAAATTTGGTGGTGC
AGCAGGGACCTTCGTCCCGCCATCGTGAGGGGAGTGCTGGCGAAACCTCAGGTCGCGAAAAGGCTCCACCCCTCGCCCCT
GCAAAGTTGCAGAGCCGAACCCCCAGGGGCGACAACCTCCCCAAAGACTTATCGCCATCTCCCAAGGCGGGATCCCAAAG
CTACGGTAGAGTCGGGCAACCTCCTCCTGCTGAGCCAGAGACCCCTGGCGAGAACTCCATCCCGCCAGCGCAAGCGGCAA
AGCCTCCCTCCTACCACCTTGCCCACGAGCTGGCGGAGGTGGCCCGCCGCTTTGCCGACCATTTCAACGGCAGCCTGATA
GATTTGCAAGGGATCCTGGCCTCGCCCGAGGAGGCGACGGCAGAACTGTCCGCTCTCGAGAGCCTGGAAGCAGAGGGATC
CCCGGATCTGGGTGAAGCCTACGGCCCGCCGGCAACCCAGTCCCCCCTAGCCCCCGCAGAGGAGGAGCTACCTTTCTAG

Upstream 100 bases:

>100_bases
AAGCCAGAATAGGGGAGCCCCCCTGGGATGCCTCAGCATTGCCCAGCAAGAGCGGTTTCGGCGGGGGCGCGCTTGCAAGG
CGACTGGAGAGCTCGAAAAA

Downstream 100 bases:

>100_bases
GCGTTACTTTGGGATTGTCTTGACCCTTGGGCCCCATGATCTGATCCGCTTCTCGGCGCAGGCGCCGGACTGGGCGCTGG
TTCTGCCCCTGCCACTTTGG

Product: DNA polymerase III, subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MAVAGKYEPLHLKYRPQRFAEVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSARILAKSLNCEQGPTPDPCQVC
SQCRAITAGSSLDVIEIDAASNTGVDNIRELIERAQFAPVNSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLAT
TDPQRVLPTIVSRCQRFDFRRIPLDDMVAHLGQIAAQEGIPIAPEALHLVAQLAQGGLRDAERLLDQLSLLEGSITPEAV
WDLVGGIPERQLLDLTDALLAQDVQAVLAQTRQLLERGREPLVVLQSLVVFYRDLLLAKTAPQQRQLAAVTDPTWAALQQ
RAPRYSVEMLLAAQSHLRQCEPQIRQSGQPQLWLEIALLDLLGQLRQSAVPLPSIEAKGGEPLPAVGPPTVGKTPSPTVP
ASEELTAPTTTLPETPAPSPAATGGSLPPSQTAKPSREKPASPEKAKDPHPLKLLRPRWEEFLENLRPITRGLLASGYLQ
QESLVGSDGTETLEITLAFPNKGLVDKVRSKEAELCSALHNLLQRPVRLNLVVQQGPSSRHREGSAGETSGREKAPPLAP
AKLQSRTPRGDNLPKDLSPSPKAGSQSYGRVGQPPPAEPETPGENSIPPAQAAKPPSYHLAHELAEVARRFADHFNGSLI
DLQGILASPEEATAELSALESLEAEGSPDLGEAYGPPATQSPLAPAEEELPF

Sequences:

>Translated_692_residues
MAVAGKYEPLHLKYRPQRFAEVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSARILAKSLNCEQGPTPDPCQVC
SQCRAITAGSSLDVIEIDAASNTGVDNIRELIERAQFAPVNSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLAT
TDPQRVLPTIVSRCQRFDFRRIPLDDMVAHLGQIAAQEGIPIAPEALHLVAQLAQGGLRDAERLLDQLSLLEGSITPEAV
WDLVGGIPERQLLDLTDALLAQDVQAVLAQTRQLLERGREPLVVLQSLVVFYRDLLLAKTAPQQRQLAAVTDPTWAALQQ
RAPRYSVEMLLAAQSHLRQCEPQIRQSGQPQLWLEIALLDLLGQLRQSAVPLPSIEAKGGEPLPAVGPPTVGKTPSPTVP
ASEELTAPTTTLPETPAPSPAATGGSLPPSQTAKPSREKPASPEKAKDPHPLKLLRPRWEEFLENLRPITRGLLASGYLQ
QESLVGSDGTETLEITLAFPNKGLVDKVRSKEAELCSALHNLLQRPVRLNLVVQQGPSSRHREGSAGETSGREKAPPLAP
AKLQSRTPRGDNLPKDLSPSPKAGSQSYGRVGQPPPAEPETPGENSIPPAQAAKPPSYHLAHELAEVARRFADHFNGSLI
DLQGILASPEEATAELSALESLEAEGSPDLGEAYGPPATQSPLAPAEEELPF
>Mature_691_residues
AVAGKYEPLHLKYRPQRFAEVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSARILAKSLNCEQGPTPDPCQVCS
QCRAITAGSSLDVIEIDAASNTGVDNIRELIERAQFAPVNSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLATT
DPQRVLPTIVSRCQRFDFRRIPLDDMVAHLGQIAAQEGIPIAPEALHLVAQLAQGGLRDAERLLDQLSLLEGSITPEAVW
DLVGGIPERQLLDLTDALLAQDVQAVLAQTRQLLERGREPLVVLQSLVVFYRDLLLAKTAPQQRQLAAVTDPTWAALQQR
APRYSVEMLLAAQSHLRQCEPQIRQSGQPQLWLEIALLDLLGQLRQSAVPLPSIEAKGGEPLPAVGPPTVGKTPSPTVPA
SEELTAPTTTLPETPAPSPAATGGSLPPSQTAKPSREKPASPEKAKDPHPLKLLRPRWEEFLENLRPITRGLLASGYLQQ
ESLVGSDGTETLEITLAFPNKGLVDKVRSKEAELCSALHNLLQRPVRLNLVVQQGPSSRHREGSAGETSGREKAPPLAPA
KLQSRTPRGDNLPKDLSPSPKAGSQSYGRVGQPPPAEPETPGENSIPPAQAAKPPSYHLAHELAEVARRFADHFNGSLID
LQGILASPEEATAELSALESLEAEGSPDLGEAYGPPATQSPLAPAEEELPF

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=279, Percent_Identity=28.673835125448, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI31881687, Length=279, Percent_Identity=28.673835125448, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI6677723, Length=253, Percent_Identity=26.4822134387352, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194306571, Length=253, Percent_Identity=26.4822134387352, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI194306567, Length=253, Percent_Identity=26.4822134387352, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI31563534, Length=244, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI194306569, Length=172, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786676, Length=297, Percent_Identity=45.4545454545455, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1787341, Length=150, Percent_Identity=34.6666666666667, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=313, Percent_Identity=23.961661341853, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554730, Length=273, Percent_Identity=25.6410256410256, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324039, Length=246, Percent_Identity=26.0162601626016, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322528, Length=305, Percent_Identity=24.5901639344262, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=235, Percent_Identity=23.4042553191489, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859927, Length=275, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17647857, Length=274, Percent_Identity=25.5474452554745, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921076, Length=243, Percent_Identity=26.3374485596708, Blast_Score=81, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 74420; Mature: 74288

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAGKYEPLHLKYRPQRFAEVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSAR
CCCCCCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
ILAKSLNCEQGPTPDPCQVCSQCRAITAGSSLDVIEIDAASNTGVDNIRELIERAQFAPV
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCC
NSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLATTDPQRVLPTIVSRCQRFDFR
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
RIPLDDMVAHLGQIAAQEGIPIAPEALHLVAQLAQGGLRDAERLLDQLSLLEGSITPEAV
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHH
WDLVGGIPERQLLDLTDALLAQDVQAVLAQTRQLLERGREPLVVLQSLVVFYRDLLLAKT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
APQQRQLAAVTDPTWAALQQRAPRYSVEMLLAAQSHLRQCEPQIRQSGQPQLWLEIALLD
CCHHHHEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
LLGQLRQSAVPLPSIEAKGGEPLPAVGPPTVGKTPSPTVPASEELTAPTTTLPETPAPSP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AATGGSLPPSQTAKPSREKPASPEKAKDPHPLKLLRPRWEEFLENLRPITRGLLASGYLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QESLVGSDGTETLEITLAFPNKGLVDKVRSKEAELCSALHNLLQRPVRLNLVVQQGPSSR
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCC
HREGSAGETSGREKAPPLAPAKLQSRTPRGDNLPKDLSPSPKAGSQSYGRVGQPPPAEPE
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPGENSIPPAQAAKPPSYHLAHELAEVARRFADHFNGSLIDLQGILASPEEATAELSALE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHH
SLEAEGSPDLGEAYGPPATQSPLAPAEEELPF
HHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AVAGKYEPLHLKYRPQRFAEVVGQGAVVQTLANAIRLGRVAPAYLFCGPRGTGKTSSAR
CCCCCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
ILAKSLNCEQGPTPDPCQVCSQCRAITAGSSLDVIEIDAASNTGVDNIRELIERAQFAPV
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCC
NSRYKVYVIDECHMLSNAAFNALLKTLEEPPPRVVFVLATTDPQRVLPTIVSRCQRFDFR
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
RIPLDDMVAHLGQIAAQEGIPIAPEALHLVAQLAQGGLRDAERLLDQLSLLEGSITPEAV
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHH
WDLVGGIPERQLLDLTDALLAQDVQAVLAQTRQLLERGREPLVVLQSLVVFYRDLLLAKT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
APQQRQLAAVTDPTWAALQQRAPRYSVEMLLAAQSHLRQCEPQIRQSGQPQLWLEIALLD
CCHHHHEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHH
LLGQLRQSAVPLPSIEAKGGEPLPAVGPPTVGKTPSPTVPASEELTAPTTTLPETPAPSP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AATGGSLPPSQTAKPSREKPASPEKAKDPHPLKLLRPRWEEFLENLRPITRGLLASGYLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QESLVGSDGTETLEITLAFPNKGLVDKVRSKEAELCSALHNLLQRPVRLNLVVQQGPSSR
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCC
HREGSAGETSGREKAPPLAPAKLQSRTPRGDNLPKDLSPSPKAGSQSYGRVGQPPPAEPE
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPGENSIPPAQAAKPPSYHLAHELAEVARRFADHFNGSLIDLQGILASPEEATAELSALE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHH
SLEAEGSPDLGEAYGPPATQSPLAPAEEELPF
HHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]