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The map label for this gene is emrY [H]

Identifier: 86361278

GI number: 86361278

Start: 614771

End: 616369

Strand: Reverse

Name: emrY [H]

Synonym: RHE_PF00550

Alternate gene names: 86361278

Gene position: 616369-614771 (Counterclockwise)

Preceding gene: 86361279

Following gene: 86361277

Centisome position: 95.93

GC content: 60.79

Gene sequence:

>1599_bases
ATGTCGCTCGTTTTCGGTCCGCTGACCAGCGGCAGGACCGCAAGCCGTCCCTATCTCATCGTCGCCGCACTCCTCCTGGC
ATCTTTCGTGGTCGGTTTCGACACGCGGGTATTCTCTGTCGGCCTTCCGGATCTGCGCGGCGCCTATTCGCTCGGTGCCG
ACGAGGCATCCTGGCTGAGCACGATCGCCAACGCGCCGCAAATTCTCATCGCTTCGGCAGTCGCCTGGCTTGTCACCGTC
TTCGGCATCCGCCGCGTGATGATCCCGTCCGCGCTCATCTATGCCGCCGTCTCGCTTGCCATTCCTCAGGTCACGGGCGG
GACGGCGCTTTTCGTGCTCCATGCGCTGAGGGGGCTTCTGCTCGGCGTGTTCATCCCCGCGACCCTCATGGTGATATTCC
GGAACCTTTCGACCAAATACTGGCTGATCGGCATCGGGCTCTATGCGCTGCGTGTCCCTCTGTCGCAGAGCCTCGGCTTC
GTGCTGGTCGGCATCTACGGCGACTATCTCGGCTGGCAGTGGCTTTATTGGCAGGATGTGATCGTCGCCCCTGTCATCGC
GCTCCTGCTGGTCGTTGGTGCGCCGAAGGAAGAGATCAACATCGGGTTGCTCGAAAGGGCCGACTGGGGCGGAATGCTGC
TGCTCGGATCATCGATGACGATGCTCTACGTCGCGCTCGACCAGGGCAACCGGCTCGACTGGTTCCAATCGGGTGTCGTG
ACCTCGCTGCTGGTTGGTGGAGCGGTTCTCGCAGCCTGCTTCCTCGTCAATGAAAGCCTTGTCGAGCGGCCCTGGGCGCA
TGCAAGCGTCATCCTGTCGCGCAACATCGGCATCGGCTATGCCGTCATCATCTGCTTCAGTCTCAGCAGCGCCGGCGGTT
CCATTTCCGTTCCCGGCTTCCTGCAGAATGTCGGCGGCCTGAGGCCGATCGCCGCCTCCGACCTCTATTTCGCAGGCGCG
GTCATTCCGGTGTTTCTATTCACGGCGATGGCGATCGTCCTCCAGAGCCGGGTAGATTCGAGGTTCTGCATCATCATCGG
TCTTCTGATGATGGCGGCAGGGGCGTTTTTGGGATCTCAGCTGACCAAGGCATGGTCGGCCTCGAATTTCCTGATTCCGG
TGCTGTTGTACACAGCCGGCCAGTCATTCGCCTTTTTCTCGACCGTCGTTTATCTTATCGCCAATTCGGACCCCGCACGC
TCGACCGCCGTATCGGCCTATATTCAGGTCATAAGGCTTGGCAGCGTCGAACTGGCCACCAGCCTGATGACCACCTGGCT
GCGGCGGCGGGAGCAATTTCACTCCAATGTGCTCGGACACCGGATCACCGCCGCCTCACCTGAGCTTCATGCATGGACGT
CAAAAATAGCCTCGCTTCTCGATGGGCATGCCCGCAGTGGTCTCGAGACACTGTCGATTGCCGCGACGCAACTGCGCGCA
CAGGCTTATGTCCTGGCCTATTCCGACTTATTCATGTTGTCCTTCTGGTCGGCAGTATCGGGTCTGCTTCTGGTTTCCCT
GATGGGCGCAATGCCCTTCGGGCCGCTGCACCCCGACTTCACGCATGAGCAGAACGCGGGGCCGCGGAAAACAGCATAA

Upstream 100 bases:

>100_bases
TAGAGCTTGATCCGGATCAGCCCCTGATTGACCAGCTGAGACCGGGAATGTCGGCCATCGTGACGGTCGATACCCCTGCG
GGAGCCAGCCGGTGAGCCAG

Downstream 100 bases:

>100_bases
CCCAGCGATAAATGTGAGAGACAAGAGCGCGAAAAACGCGATACCGTCGCGTGGCCGAAGCGGGGGCAAGGTATAGCGAC
CGACACTAATGTGTAGGTCA

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSLVFGPLTSGRTASRPYLIVAALLLASFVVGFDTRVFSVGLPDLRGAYSLGADEASWLSTIANAPQILIASAVAWLVTV
FGIRRVMIPSALIYAAVSLAIPQVTGGTALFVLHALRGLLLGVFIPATLMVIFRNLSTKYWLIGIGLYALRVPLSQSLGF
VLVGIYGDYLGWQWLYWQDVIVAPVIALLLVVGAPKEEINIGLLERADWGGMLLLGSSMTMLYVALDQGNRLDWFQSGVV
TSLLVGGAVLAACFLVNESLVERPWAHASVILSRNIGIGYAVIICFSLSSAGGSISVPGFLQNVGGLRPIAASDLYFAGA
VIPVFLFTAMAIVLQSRVDSRFCIIIGLLMMAAGAFLGSQLTKAWSASNFLIPVLLYTAGQSFAFFSTVVYLIANSDPAR
STAVSAYIQVIRLGSVELATSLMTTWLRRREQFHSNVLGHRITAASPELHAWTSKIASLLDGHARSGLETLSIAATQLRA
QAYVLAYSDLFMLSFWSAVSGLLLVSLMGAMPFGPLHPDFTHEQNAGPRKTA

Sequences:

>Translated_532_residues
MSLVFGPLTSGRTASRPYLIVAALLLASFVVGFDTRVFSVGLPDLRGAYSLGADEASWLSTIANAPQILIASAVAWLVTV
FGIRRVMIPSALIYAAVSLAIPQVTGGTALFVLHALRGLLLGVFIPATLMVIFRNLSTKYWLIGIGLYALRVPLSQSLGF
VLVGIYGDYLGWQWLYWQDVIVAPVIALLLVVGAPKEEINIGLLERADWGGMLLLGSSMTMLYVALDQGNRLDWFQSGVV
TSLLVGGAVLAACFLVNESLVERPWAHASVILSRNIGIGYAVIICFSLSSAGGSISVPGFLQNVGGLRPIAASDLYFAGA
VIPVFLFTAMAIVLQSRVDSRFCIIIGLLMMAAGAFLGSQLTKAWSASNFLIPVLLYTAGQSFAFFSTVVYLIANSDPAR
STAVSAYIQVIRLGSVELATSLMTTWLRRREQFHSNVLGHRITAASPELHAWTSKIASLLDGHARSGLETLSIAATQLRA
QAYVLAYSDLFMLSFWSAVSGLLLVSLMGAMPFGPLHPDFTHEQNAGPRKTA
>Mature_531_residues
SLVFGPLTSGRTASRPYLIVAALLLASFVVGFDTRVFSVGLPDLRGAYSLGADEASWLSTIANAPQILIASAVAWLVTVF
GIRRVMIPSALIYAAVSLAIPQVTGGTALFVLHALRGLLLGVFIPATLMVIFRNLSTKYWLIGIGLYALRVPLSQSLGFV
LVGIYGDYLGWQWLYWQDVIVAPVIALLLVVGAPKEEINIGLLERADWGGMLLLGSSMTMLYVALDQGNRLDWFQSGVVT
SLLVGGAVLAACFLVNESLVERPWAHASVILSRNIGIGYAVIICFSLSSAGGSISVPGFLQNVGGLRPIAASDLYFAGAV
IPVFLFTAMAIVLQSRVDSRFCIIIGLLMMAAGAFLGSQLTKAWSASNFLIPVLLYTAGQSFAFFSTVVYLIANSDPARS
TAVSAYIQVIRLGSVELATSLMTTWLRRREQFHSNVLGHRITAASPELHAWTSKIASLLDGHARSGLETLSIAATQLRAQ
AYVLAYSDLFMLSFWSAVSGLLLVSLMGAMPFGPLHPDFTHEQNAGPRKTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=507, Percent_Identity=24.2603550295858, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789042, Length=493, Percent_Identity=24.3407707910751, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56998; Mature: 56866

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVFGPLTSGRTASRPYLIVAALLLASFVVGFDTRVFSVGLPDLRGAYSLGADEASWLS
CCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHCCCCHHHHHH
TIANAPQILIASAVAWLVTVFGIRRVMIPSALIYAAVSLAIPQVTGGTALFVLHALRGLL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGVFIPATLMVIFRNLSTKYWLIGIGLYALRVPLSQSLGFVLVGIYGDYLGWQWLYWQDV
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCHHHCCCEEEEEEHHHHHCCCHHHHHHH
IVAPVIALLLVVGAPKEEINIGLLERADWGGMLLLGSSMTMLYVALDQGNRLDWFQSGVV
HHHHHHHHHHHHCCCHHHCCEEEEEECCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHH
TSLLVGGAVLAACFLVNESLVERPWAHASVILSRNIGIGYAVIICFSLSSAGGSISVPGF
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHHHHHHCCCCCCEECCHH
LQNVGGLRPIAASDLYFAGAVIPVFLFTAMAIVLQSRVDSRFCIIIGLLMMAAGAFLGSQ
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LTKAWSASNFLIPVLLYTAGQSFAFFSTVVYLIANSDPARSTAVSAYIQVIRLGSVELAT
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHH
SLMTTWLRRREQFHSNVLGHRITAASPELHAWTSKIASLLDGHARSGLETLSIAATQLRA
HHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QAYVLAYSDLFMLSFWSAVSGLLLVSLMGAMPFGPLHPDFTHEQNAGPRKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLVFGPLTSGRTASRPYLIVAALLLASFVVGFDTRVFSVGLPDLRGAYSLGADEASWLS
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHCCCCHHHHHH
TIANAPQILIASAVAWLVTVFGIRRVMIPSALIYAAVSLAIPQVTGGTALFVLHALRGLL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGVFIPATLMVIFRNLSTKYWLIGIGLYALRVPLSQSLGFVLVGIYGDYLGWQWLYWQDV
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCHHHCCCEEEEEEHHHHHCCCHHHHHHH
IVAPVIALLLVVGAPKEEINIGLLERADWGGMLLLGSSMTMLYVALDQGNRLDWFQSGVV
HHHHHHHHHHHHCCCHHHCCEEEEEECCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHH
TSLLVGGAVLAACFLVNESLVERPWAHASVILSRNIGIGYAVIICFSLSSAGGSISVPGF
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHHHHHHCCCCCCEECCHH
LQNVGGLRPIAASDLYFAGAVIPVFLFTAMAIVLQSRVDSRFCIIIGLLMMAAGAFLGSQ
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LTKAWSASNFLIPVLLYTAGQSFAFFSTVVYLIANSDPARSTAVSAYIQVIRLGSVELAT
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHH
SLMTTWLRRREQFHSNVLGHRITAASPELHAWTSKIASLLDGHARSGLETLSIAATQLRA
HHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QAYVLAYSDLFMLSFWSAVSGLLLVSLMGAMPFGPLHPDFTHEQNAGPRKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]