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The map label for this gene is vbsO

Identifier: 86361186

GI number: 86361186

Start: 512498

End: 513856

Strand: Reverse

Name: vbsO

Synonym: RHE_PF00456

Alternate gene names: 86361186

Gene position: 513856-512498 (Counterclockwise)

Preceding gene: 86361187

Following gene: 86361181

Centisome position: 79.98

GC content: 62.69

Gene sequence:

>1359_bases
ATGACCGTCGCTTTTACCCGCAGGGATGCCCTCAACGAGCCGCTCGATCTTGCCGGCATCGGCATCGGTCCCTCCAATCT
GAGCCTTGCCTGCCTGCTGGAATCCGTGCCCGAAGTGCGCAGCCGCTTCTTCGAGCGGCGAGCCTCGTTCGACTGGCATC
CCGGCATGATGATGCCCGGGGTCGAGCTGCAATCATCCTTCCTGAAGGACCTCGTCACGCCGGTCCTGCCGACGAGCCGC
TGGTCGTTCGTCTCCTATCTGGTGGCGCATAAGCGGCTCTACGCCTTCCTGAACGCCAATTACGAGGCCGTTCCCCGGCA
GGAATTTGCGCGCTATCTCGCCTGGGTCGCCAATGGCGTTGACGGCTTGCGCTACGCAACTGAAATTCGCGACGTGGAGC
ACCGCGACGACCGTTTCGTCCTGCGCTTCGACAACGGCCAGGAAGAAGCGACGAATCTGGTGATCGGTACGGGGTCTTCG
CCCTTCGTGCCCGACTGGGCGAAACCCTTCCTTGGGCCCGATTGCTTCCACAACAGCGATGCCAAGTCGCGTCTCAAGGA
TCTTCGCGCCGGCCGCATCGTCGTGGTCGGCGGCGGCCAGAGCGGCGGCGAGGTGGTCGACGCGCTGCTTGGGGATGCCA
GCTCGATCAAGGAGCTGACCTGGATCAGCCGGCGCCACAATTTCGAGCCGATCAACGACACGCCGTTTTCGAACCAGGTC
TTCTCGCCGGAATATGTGCAGGCCTATCTGAAGCTCAGCGGCGAGCAGAAACAGGCGGCGCTGAAGAACTCGATCCTGAC
CAGCGACGGCCTGTCGATCTCGACGATCCACTCGATCTACCGACGCCTCTACGCGCTGCGGTATCTCGATCAGAGCACGC
TGAACGCATCTCTGTCGCCGAACCGCGACGTGATCCAGATGGAGCGGAACGGCAATGCCTATCGGCTGATCGTCCGCAAC
CATTTCGACGGCGGGATCGAGGTGCTGCATGCCGATGCGGTGGTGCTGGCCACCGGCTACAGGTTCCGTTTGCCGGATGC
GCTCGGTTCGCTCGGCGAAAGGATCAGCCTCGACAGAAATGGATATCCCACCTTGAACGACGACTACACGATGCAGTGGA
CAGGCCCGAGGTCCAACCGGCTGTTTGCCCAGAATGCCGGCCGATACTCGCACGGCATCGCCGACTCGCAGCTCAGTCTC
ATGGCCTGGCGCAGCGCCAAGATCGTCAACACGATTCTCGGCCGGCAGCATTTCGATGCCGAACCCGACAATGCGCAGCT
GGTCTGGGCGACGGAGGCAGCTTCCGCCATGCCGCATCAGCTCCGGGTCGGCTATGGGGACGGCATGCTCTCGTCCTGA

Upstream 100 bases:

>100_bases
CCGAAATCATCACCGGCACCAACCATCTGCACATGATCGGGTCTCCCGCCTTCCATTCAAGGCTTGCCCTGCGTCTCAAG
GAAACAGAGAAGGATAACGC

Downstream 100 bases:

>100_bases
AACGTCAGGACATGAATGCCGGGCGCGGCGGATGATGAGCGGGCGGCCAGTGCGACGACGTGCTGGCTGCCGCTCTCGAC
CAGGCGGTGATGCCATTGCC

Product: L-lysine 6-monooxygenase (lysine N(6)-hydroxylase) protein

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTVAFTRRDALNEPLDLAGIGIGPSNLSLACLLESVPEVRSRFFERRASFDWHPGMMMPGVELQSSFLKDLVTPVLPTSR
WSFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGVDGLRYATEIRDVEHRDDRFVLRFDNGQEEATNLVIGTGSS
PFVPDWAKPFLGPDCFHNSDAKSRLKDLRAGRIVVVGGGQSGGEVVDALLGDASSIKELTWISRRHNFEPINDTPFSNQV
FSPEYVQAYLKLSGEQKQAALKNSILTSDGLSISTIHSIYRRLYALRYLDQSTLNASLSPNRDVIQMERNGNAYRLIVRN
HFDGGIEVLHADAVVLATGYRFRLPDALGSLGERISLDRNGYPTLNDDYTMQWTGPRSNRLFAQNAGRYSHGIADSQLSL
MAWRSAKIVNTILGRQHFDAEPDNAQLVWATEAASAMPHQLRVGYGDGMLSS

Sequences:

>Translated_452_residues
MTVAFTRRDALNEPLDLAGIGIGPSNLSLACLLESVPEVRSRFFERRASFDWHPGMMMPGVELQSSFLKDLVTPVLPTSR
WSFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGVDGLRYATEIRDVEHRDDRFVLRFDNGQEEATNLVIGTGSS
PFVPDWAKPFLGPDCFHNSDAKSRLKDLRAGRIVVVGGGQSGGEVVDALLGDASSIKELTWISRRHNFEPINDTPFSNQV
FSPEYVQAYLKLSGEQKQAALKNSILTSDGLSISTIHSIYRRLYALRYLDQSTLNASLSPNRDVIQMERNGNAYRLIVRN
HFDGGIEVLHADAVVLATGYRFRLPDALGSLGERISLDRNGYPTLNDDYTMQWTGPRSNRLFAQNAGRYSHGIADSQLSL
MAWRSAKIVNTILGRQHFDAEPDNAQLVWATEAASAMPHQLRVGYGDGMLSS
>Mature_451_residues
TVAFTRRDALNEPLDLAGIGIGPSNLSLACLLESVPEVRSRFFERRASFDWHPGMMMPGVELQSSFLKDLVTPVLPTSRW
SFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGVDGLRYATEIRDVEHRDDRFVLRFDNGQEEATNLVIGTGSSP
FVPDWAKPFLGPDCFHNSDAKSRLKDLRAGRIVVVGGGQSGGEVVDALLGDASSIKELTWISRRHNFEPINDTPFSNQVF
SPEYVQAYLKLSGEQKQAALKNSILTSDGLSISTIHSIYRRLYALRYLDQSTLNASLSPNRDVIQMERNGNAYRLIVRNH
FDGGIEVLHADAVVLATGYRFRLPDALGSLGERISLDRNGYPTLNDDYTMQWTGPRSNRLFAQNAGRYSHGIADSQLSLM
AWRSAKIVNTILGRQHFDAEPDNAQLVWATEAASAMPHQLRVGYGDGMLSS

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 50449; Mature: 50318

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAFTRRDALNEPLDLAGIGIGPSNLSLACLLESVPEVRSRFFERRASFDWHPGMMMPG
CEEEEECHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VELQSSFLKDLVTPVLPTSRWSFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
DGLRYATEIRDVEHRDDRFVLRFDNGQEEATNLVIGTGSSPFVPDWAKPFLGPDCFHNSD
CHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHCCCCHHCCCCC
AKSRLKDLRAGRIVVVGGGQSGGEVVDALLGDASSIKELTWISRRHNFEPINDTPFSNQV
HHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
FSPEYVQAYLKLSGEQKQAALKNSILTSDGLSISTIHSIYRRLYALRYLDQSTLNASLSP
CCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NRDVIQMERNGNAYRLIVRNHFDGGIEVLHADAVVLATGYRFRLPDALGSLGERISLDRN
CCCEEEEECCCCEEEEEEEECCCCCEEEEECCEEEEECCCEEECCHHHHHHHHEEECCCC
GYPTLNDDYTMQWTGPRSNRLFAQNAGRYSHGIADSQLSLMAWRSAKIVNTILGRQHFDA
CCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
EPDNAQLVWATEAASAMPHQLRVGYGDGMLSS
CCCCCEEEEEECHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TVAFTRRDALNEPLDLAGIGIGPSNLSLACLLESVPEVRSRFFERRASFDWHPGMMMPG
EEEEECHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VELQSSFLKDLVTPVLPTSRWSFVSYLVAHKRLYAFLNANYEAVPRQEFARYLAWVANGV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
DGLRYATEIRDVEHRDDRFVLRFDNGQEEATNLVIGTGSSPFVPDWAKPFLGPDCFHNSD
CHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHCCCCHHCCCCC
AKSRLKDLRAGRIVVVGGGQSGGEVVDALLGDASSIKELTWISRRHNFEPINDTPFSNQV
HHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
FSPEYVQAYLKLSGEQKQAALKNSILTSDGLSISTIHSIYRRLYALRYLDQSTLNASLSP
CCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NRDVIQMERNGNAYRLIVRNHFDGGIEVLHADAVVLATGYRFRLPDALGSLGERISLDRN
CCCEEEEECCCCEEEEEEEECCCCCEEEEECCEEEEECCCEEECCHHHHHHHHEEECCCC
GYPTLNDDYTMQWTGPRSNRLFAQNAGRYSHGIADSQLSLMAWRSAKIVNTILGRQHFDA
CCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
EPDNAQLVWATEAASAMPHQLRVGYGDGMLSS
CCCCCEEEEEECHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]