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The map label for this gene is mcpCf

Identifier: 86361181

GI number: 86361181

Start: 506095

End: 507972

Strand: Reverse

Name: mcpCf

Synonym: RHE_PF00451

Alternate gene names: 86361181

Gene position: 507972-506095 (Counterclockwise)

Preceding gene: 86361186

Following gene: 86361180

Centisome position: 79.06

GC content: 59.53

Gene sequence:

>1878_bases
ATGAAGCGCCCGAGTATCAAGCAAGCTCTCATCCTGAACCTGTCCATCATCAGCATGTTCATACTTGGTCTGTCCTATGT
CTCGCTGGACACCATTTCCTCGCTTCGCTCAAATGCGGAACAGGTCGGTACGTTCTGGGTGCATCGGCTGGTGACGGCGC
GTGAAATCAAAGCGAACTTTCTTGATCTGAAACTTGCCCATGCTCGGTATTTGCTCGAAGACACGGTGGAAAACGACAAA
ACCGGAAAGCAGGCGATCGCGGCCGCTTCATCGGGGCTCGACACGGTTGTTGGCGATTACGAAAAGGGCGTTCGCACCGA
GCGCGGGCGCCAGCTGATCAATCAGATAAAGCCGGAACTCGACAAATATCGCGCGTTGGCGGAGCAAATGATTGCGCTCG
AAGACAGCGGCAAGACAGCTGAGGCAGTCCGGCTTTTCAAGGAGAAGATGGAGCCGCAGGCCGAGCTGGTGAACAGGGGG
GTGGCGGATCTGGTGGCATTCATTCTCAGCCAGACCGAAAGCTTCGTAGCGGCAAGCGATGCGTCCGCGAATTCCGCTTT
CATGCTGACAGCTGCGATCGCCTCGCTGGCCTTGCTCGTGGCTATCGCGGGTATCGTCTTTGCGATTTCCGGCATTGCCA
ATCCGATCCGCAATACAGCGTTCGCCATGAAGCGGTTGTCGGCTGGAGATCTCGACAGCGATATTCCATATGCCGGCCGC
GCGGACGAAATCGGTGAAATGGCCGGCGCAGTTGAAGTGTTTCGCCAGAATGCCCTCAACGTTGTCAGGCTTGAGAAGGA
AGCTGCCGAATCCCGCAGTGAGAGCGAGGCGGCGCGGGCCGCAGCCCAGCAGCGTGCCGAACGCGAAGCCGAGCAGCTGC
GCTTTGCAACCACCACCTTGGGCGGGGGCCTCCGGCGCCTTGCCGCGGGCGACATATCCTTCCAGATCTCGGAGCGATTT
GCCGCTGAATACGAAGCATTGCGCGACGACTTCAATACTTCGCTGCGGCAATTGGGCGCGACGATCGGCGCGGTGCTCCA
GACGGTACACAGCATAGACAACGGTACCGGTGAAATAGCATCCGGTGCCCAGGACCTGTCGAAGCGCACGGAACAACAGG
CCGCTTCACTCGAGGAGACCGCCGCCGCGTTGGACGAGATTACCTCGAATGTCGCGATGGCGACGAAACGCACCGAGGAG
GCGCGCAATATCTCTGTGGAAGCCAATGTCAGCGCCCAGCGCTCGGCCACGATCGTGTCGGAGGCGGAGCAGGCCATGCG
ACGCATCGAGGACAGTTCGCAGCAGATTTCCAACATCATTGGCGTCATCGACGAAATTGCTTTCCAGACGAACCTGCTGG
CGCTCAACGCCGGTGTCGAGGCAGCGCGCGCAGGTGAGGCAGGAAAGGGTTTTGCGGTGGTCGCACAAGAAGTCCGGGAA
CTGGCGCAACGAGCCGCGCAGGCGGCCAAGGAAATCAAAGGTCTCATCCAGAAGTCGTCGACCGAAGTCGAGCACGGGGT
CAAACTTGTACTCGAAACCGGAACGTCACTGAAATCGATCGGCGAACGCGTGGCCGAAATTAATCGAGCCATGGACGCGA
TCGCCACCTCGGCGCGCGAGCAGGCGACCGGGCTTTCCGAGATCAACACGGCGATCAATCACATGGATCAGGCAACTCAG
CAGAATGCGGCGATGGTCGAGCAGTCCACGGCCGCCGCCTCTTCACTAGCCTCAGAAGCAAGCCGCCTGCGCGAGCTGGT
CAATCAGTTCCAATTGGATGGTGACAGAGGCCCAGTGAATGCCCAGTCCAATACGCACTCCGTGGAAAGCAGCATGCCGT
CGCAGGTGGTCGCTCTGCGGCCCGCGATGCGAAGGTAA

Upstream 100 bases:

>100_bases
TGAAAACCGGACGACTCTCCTCGTTTAGTTAATACTAAATTATCGAATCCGATGGGAGATTCGCATTAACCGGCAGCGAC
CGTCCCAAGAGGAGACCCGC

Downstream 100 bases:

>100_bases
ATTTGCCGCCGTGGTCAGTCTCGTCAGTTTGAAGGGACGACTCCCTGATGAGAAGAATGGTGCAGCTTCAGGCTGTGCTG
CTGTGGACAAAGAGGTTCCG

Product: methyl accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MKRPSIKQALILNLSIISMFILGLSYVSLDTISSLRSNAEQVGTFWVHRLVTAREIKANFLDLKLAHARYLLEDTVENDK
TGKQAIAAASSGLDTVVGDYEKGVRTERGRQLINQIKPELDKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNRG
VADLVAFILSQTESFVAASDASANSAFMLTAAIASLALLVAIAGIVFAISGIANPIRNTAFAMKRLSAGDLDSDIPYAGR
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGGGLRRLAAGDISFQISERF
AAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIASGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEE
ARNISVEANVSAQRSATIVSEAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMDAIATSAREQATGLSEINTAINHMDQATQ
QNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPVNAQSNTHSVESSMPSQVVALRPAMRR

Sequences:

>Translated_625_residues
MKRPSIKQALILNLSIISMFILGLSYVSLDTISSLRSNAEQVGTFWVHRLVTAREIKANFLDLKLAHARYLLEDTVENDK
TGKQAIAAASSGLDTVVGDYEKGVRTERGRQLINQIKPELDKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNRG
VADLVAFILSQTESFVAASDASANSAFMLTAAIASLALLVAIAGIVFAISGIANPIRNTAFAMKRLSAGDLDSDIPYAGR
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGGGLRRLAAGDISFQISERF
AAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIASGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEE
ARNISVEANVSAQRSATIVSEAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMDAIATSAREQATGLSEINTAINHMDQATQ
QNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPVNAQSNTHSVESSMPSQVVALRPAMRR
>Mature_625_residues
MKRPSIKQALILNLSIISMFILGLSYVSLDTISSLRSNAEQVGTFWVHRLVTAREIKANFLDLKLAHARYLLEDTVENDK
TGKQAIAAASSGLDTVVGDYEKGVRTERGRQLINQIKPELDKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNRG
VADLVAFILSQTESFVAASDASANSAFMLTAAIASLALLVAIAGIVFAISGIANPIRNTAFAMKRLSAGDLDSDIPYAGR
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGGGLRRLAAGDISFQISERF
AAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIASGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEE
ARNISVEANVSAQRSATIVSEAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMDAIATSAREQATGLSEINTAINHMDQATQ
QNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPVNAQSNTHSVESSMPSQVVALRPAMRR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=43.2525951557093, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1788194, Length=294, Percent_Identity=42.8571428571429, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI2367378, Length=289, Percent_Identity=46.3667820069204, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1788195, Length=289, Percent_Identity=43.598615916955, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1789453, Length=277, Percent_Identity=36.8231046931408, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66960; Mature: 66960

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPSIKQALILNLSIISMFILGLSYVSLDTISSLRSNAEQVGTFWVHRLVTAREIKANF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLKLAHARYLLEDTVENDKTGKQAIAAASSGLDTVVGDYEKGVRTERGRQLINQIKPEL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNRGVADLVAFILSQTESFVAASD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHEECC
ASANSAFMLTAAIASLALLVAIAGIVFAISGIANPIRNTAFAMKRLSAGDLDSDIPYAGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGLRRLAAGDISFQISERFAAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEEARNISVEANVSAQRSATIVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHH
EAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMDAIATSARE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QATGLSEINTAINHMDQATQQNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPVN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AQSNTHSVESSMPSQVVALRPAMRR
CCCCCHHHHHCCCHHHHHHCHHHCC
>Mature Secondary Structure
MKRPSIKQALILNLSIISMFILGLSYVSLDTISSLRSNAEQVGTFWVHRLVTAREIKANF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLKLAHARYLLEDTVENDKTGKQAIAAASSGLDTVVGDYEKGVRTERGRQLINQIKPEL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNRGVADLVAFILSQTESFVAASD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHEECC
ASANSAFMLTAAIASLALLVAIAGIVFAISGIANPIRNTAFAMKRLSAGDLDSDIPYAGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGLRRLAAGDISFQISERFAAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEEARNISVEANVSAQRSATIVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHH
EAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMDAIATSARE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QATGLSEINTAINHMDQATQQNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPVN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AQSNTHSVESSMPSQVVALRPAMRR
CCCCCHHHHHCCCHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]