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The map label for this gene is putA

Identifier: 86361114

GI number: 86361114

Start: 432773

End: 436480

Strand: Reverse

Name: putA

Synonym: RHE_PF00384

Alternate gene names: 86361114

Gene position: 436480-432773 (Counterclockwise)

Preceding gene: 86361117

Following gene: 86361112

Centisome position: 67.93

GC content: 65.35

Gene sequence:

>3708_bases
ATGTTGAACGCAGCGATCGACCCCACATCCTCCAATGATCCCGCCGGCGGCGCACCGTTCGCCGCATTCGCGCCACCGGT
CCGACCGCAATCGGAACTTCGCCGGGCGATCACGGCCGCCTATCGCCGCCCGGAAACCGAATGCCTGCCGCCGCTCGTCG
CGGCCGCGCGCGTTTCCGAGGCGAAGCGCTATGACATTCGCAGCACGGCCCGCACGCTGATCGAGGCGCTGCGCGCCAAG
CACAAGGGCACCGGCGTCGAAGGGCTGGTGCAGGAATATTCGCTTTCCAGCCAAGAAGGGGTGGCGCTCATGTGCCTTGC
CGAAGCGCTGCTGCGTATTCCCGATACGGATACCCGCGACGCGCTGATCCGCGACAAGATTGCCGAGGGCAACTGGACCT
CACATATCGGCGGCGGCAAATCCATGTTCGTCAATGCCGCCACCTGGGGCCTCGTCGTCACCGGCAAGCTAACCTCGACG
GTCAACGATCGCAGCCTTTCGGCGGCGCTTACGCGGCTGATCGCGCGCGCCGGCGAGCCGGTCATCCGCCGCGGCGTCGA
TATGGCGATGCGCATGATGGGCGAGCAGTTCGTCACAGGCGAAACGATCGAGGAGGCGCTGAAGCGCGCTCGTCCGCTGG
AAGCCCGAGGGTTCCGCTATTCCTACGACATGCTGGGCGAGGCGGCGACGACCGCAGCAGACGCCGAGCGTTATTTCAAG
GATTATGAAAAGGCGATTCATGCCATCGGCAAGGCCTCGAACGGACGCGGCATCTATGACGGTCCTGGCATTTCGATCAA
GCTTTCGGCACTTCATCCCCGGTACAGCAGATCGCAGGCCGGCCGGGTGATGGGAGAATTGCTGCCCAAGGTCAAGGCGC
TCGCCGTTCTCGCCAAGGGTTATGATATCGGCCTCAACATCGACGCCGAGGAGGCCGATCGGCTGGAGCTTTCGCTCGAT
CTGCTGGAGGAGCTCTGCTTCGCGCCGGAGCTGGCAGGGTGGAACGGGCTCGGCTTTGTCGTGCAGGCCTATGGCAAGCG
CTGCCCCTTCGTGCTCGATTACATCATTGATCTCGCCCGCCGGTCGGGACGCCGGATGATGGTACGTCTCGTCAAGGGCG
CCTATTGGGATGCGGAGATCAAGCGCGCCCAGCTCGATGGCCTCGACGACTATCCCGTCTATACCCGCAAGATCTACACC
GACGTCGCCTACATCGCCTGTGCACGCAAGCTGCTTGCCGCCGCCGATGCGGTCTTCCCGCAATTCGCGACCCACAATGC
GCAGACGCTCGCCACGATCTATCATCTGGCGGGGCCTGATTTCGGGGTCGGCAAATACGAGTTCCAGTGCCTGCACGGCA
TGGGCGAACCGCTCTATGACGAGGTTGTCGGCAAGGAGAAGCTCGACCGGCCCTGCCGCATCTATGCGCCCGTCGGGACG
CATGAGACTCTGCTTGCCTATCTTGTCCGCCGCCTGCTCGAAAACGGCGCCAACTCCTCCTTCGTGCATCGCATTTCCGA
TCCGAATGTTTCGGTCGAGGCGCTGATCGCCGATCCGGCCGAGACCGTCGCGGCCATGCCCGTCGTCGGCGCCCCGCATG
TGCAGATTGCCGCGCCCAAGGCGCTTTACGGCAGCGCCCGCGCCAATTCGAGCGGGCTCGATCTCTCGAGCGAAGCCACG
CTTTCGGATCTGGCGCAGACGCTCGCATCCACGGCTGCGACGCCCTGGCATGCGCTGCCGATTCTCGCCGACGGCTCCAC
CGACGGCGTGACGCGCGAGGTCCTCAATCCCGCCGATCACCGCGACGTCGTCGGCACCGTGACCGAGCTGAAGGTCGAGG
AGGCCGCCCGCGTCGTTGCGATGGCAGCCGAATATGCGCCGCAATGGGCGGCCGTGCCGCCGGCAGAGCGCGCCGCATGT
CTCGATCGGGCCGCCGACATCATGCAGGCCCGCATCAAGGTGCTGATGGGCATCATCATGCGTGAGGCCGGCAAATCCGC
GGCCAACGCTGTCGGCGAAGTGCGCGAAGCGGTCGACTTCCTGCGCTATTACGCCGATCAGGCGCGCAAGACCCTCGGAC
CGTCGCATCTGCCGCTCGGCCCGATCGTCTGCATCAGCCCGTGGAATTTCCCGCTGGCGATCTTCACCGGCCAGGTTGCA
GCAGCACTCGTCGCCGGCAATCCCGTGCTGGCGAAGCCCGCCGGTGTCACGCCGATCATCGCCTCGGAGAGCGTCAAGAT
CCTCCACGAGGCCGGCGTGCCGGTCGGAGCCCTCCAATTCGTGCCCGGCAGCGGCCGCCTCGGCGCCGGCATGGTTGGGG
CGCAACAAACGGCCGGCGTCATGTTTACCGGCTCGACCGAAGTTGCCCGCATGATCCAGGCGCAGCTCGCCGAGCGCCTG
TCGGCAACCGGCAAGCCGATCCCGCTGATCGCCGAAACCGGCGGCCAGAACGGCATGATCGTCGACTCCTCGGCTTTGGC
CGAACAGGTTGTGGCCGACGTCGTAACATCGGCTTTCGACAGCGCCGGCCAGCGCTGCTCGGCGCTGCGTGTTCTCTGCC
TGCAGGACGACGTCGCCGACAGGACGCTCGCCATGCTGAAAGGCGCCTTCCGTGAGTTGACCATCGGCCGCACTGATCGC
CTAAGCATCGACGTCGGGCCAGTCATCAACGACGGCGCGAAGGCGGAGATCGACCAGCATATCGAAGCGATGCGCGGCGC
CGGCCGAAAGGTAGAACAGCTGCCGCTGCCGGAAAGCGCAGCAAAAGGCACCTTCGTTCCGCCGACAATCATCGAGATCA
AGTCCCTCTCGGACCTGACGAAGGAGGTCTTCGGGCCGGTGCTGCATGTCGTCCGCTTCAAGAGAAACGGCCTCGATCGG
CTGATCGACGACATCAACGCATCGGGCTACGGCCTCACGTTCGGGCTTCACACGCGGCTCGACGAGACGATCGCGCATGT
GACGAGTCGCATCAAGGCCGGCAACCTCTACGTCAATCGCAACATCATCGGCGCGGTTGTCGGCGTGCAGCCTTTCGGCG
GCCGCGGCCTGTCCGGAACGGGGCCGAAGGCCGGCGGTCCGCTCTACATCGGCCGCCTGGTGCAGCGCGCCCCCGTGCCG
CCGCAACAGGATTCCGTTCATACCGACCTCGCCCTTCGCGATTACATCGTCTGGCTCGACAAGAAGGGTCTGACAGACGA
GGGGGAAGCTGCGCGCGGATATGCAAGCCGCTCGGCGCTCGGTCTCGAGCGCGAGCTTACCGGGCCCGTCGGCGAGCGCA
ATCTCTATGCGCTTCATCCGCGCGGCCGAATTCTCCTCGTGCCGCAGACGGAGACGGGGCTTTATCGTCAGATCGCCGCA
GCCCTGGCGACGGGCAACCATCTCGCGGTGGACGCCGGTCCCCTGTCGAAATCGGTGCTGGCTGGTTTGCCGGCGGCCGT
CGCAAGCCGCCTTTCCTGGACATCGGACTGGGAGAAGGACGGGCCATTCTCCGGCGCGCTGGTCGAAGGTGATCGTGACA
GGGTCCTTGCCGTCAATAAGAAGATCGCCGCGCTACCCGGTCCGCTTCTGCTTGTCCAGGCTGCGACAACCGAGGAGCTT
ACGAGCGATCCCGAGGCCTATTGCCTCAACTGGCTGCTGGAGGAGGTCTCAACCTCGATCAACACCGCGGCCGCCGGGGG
CAACGCAAGCCTTATGGCGATCGGCTGA

Upstream 100 bases:

>100_bases
GAATATTCCGGGCCCCCTTTTATGGATGATGCGCTCTGGGACGACGAGCCCGGTGTTCCATCTATCCGTTAGACGCAACA
TTTACTGATCAGGGAATCCT

Downstream 100 bases:

>100_bases
GTGACGGGACGAGGGCGCTGAAAATGGGCTCTCGTTGTGCGCCTTGATCTTCGGCAGGTGATAGGCCGATAGGATGAGTT
TGCCCAAGTCTGAAAAAAAA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1235; Mature: 1235

Protein sequence:

>1235_residues
MLNAAIDPTSSNDPAGGAPFAAFAPPVRPQSELRRAITAAYRRPETECLPPLVAAARVSEAKRYDIRSTARTLIEALRAK
HKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTDTRDALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTST
VNDRSLSAALTRLIARAGEPVIRRGVDMAMRMMGEQFVTGETIEEALKRARPLEARGFRYSYDMLGEAATTAADAERYFK
DYEKAIHAIGKASNGRGIYDGPGISIKLSALHPRYSRSQAGRVMGELLPKVKALAVLAKGYDIGLNIDAEEADRLELSLD
LLEELCFAPELAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRRMMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIYT
DVAYIACARKLLAAADAVFPQFATHNAQTLATIYHLAGPDFGVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGT
HETLLAYLVRRLLENGANSSFVHRISDPNVSVEALIADPAETVAAMPVVGAPHVQIAAPKALYGSARANSSGLDLSSEAT
LSDLAQTLASTAATPWHALPILADGSTDGVTREVLNPADHRDVVGTVTELKVEEAARVVAMAAEYAPQWAAVPPAERAAC
LDRAADIMQARIKVLMGIIMREAGKSAANAVGEVREAVDFLRYYADQARKTLGPSHLPLGPIVCISPWNFPLAIFTGQVA
AALVAGNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAQQTAGVMFTGSTEVARMIQAQLAERL
SATGKPIPLIAETGGQNGMIVDSSALAEQVVADVVTSAFDSAGQRCSALRVLCLQDDVADRTLAMLKGAFRELTIGRTDR
LSIDVGPVINDGAKAEIDQHIEAMRGAGRKVEQLPLPESAAKGTFVPPTIIEIKSLSDLTKEVFGPVLHVVRFKRNGLDR
LIDDINASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYIGRLVQRAPVP
PQQDSVHTDLALRDYIVWLDKKGLTDEGEAARGYASRSALGLERELTGPVGERNLYALHPRGRILLVPQTETGLYRQIAA
ALATGNHLAVDAGPLSKSVLAGLPAAVASRLSWTSDWEKDGPFSGALVEGDRDRVLAVNKKIAALPGPLLLVQAATTEEL
TSDPEAYCLNWLLEEVSTSINTAAAGGNASLMAIG

Sequences:

>Translated_1235_residues
MLNAAIDPTSSNDPAGGAPFAAFAPPVRPQSELRRAITAAYRRPETECLPPLVAAARVSEAKRYDIRSTARTLIEALRAK
HKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTDTRDALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTST
VNDRSLSAALTRLIARAGEPVIRRGVDMAMRMMGEQFVTGETIEEALKRARPLEARGFRYSYDMLGEAATTAADAERYFK
DYEKAIHAIGKASNGRGIYDGPGISIKLSALHPRYSRSQAGRVMGELLPKVKALAVLAKGYDIGLNIDAEEADRLELSLD
LLEELCFAPELAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRRMMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIYT
DVAYIACARKLLAAADAVFPQFATHNAQTLATIYHLAGPDFGVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGT
HETLLAYLVRRLLENGANSSFVHRISDPNVSVEALIADPAETVAAMPVVGAPHVQIAAPKALYGSARANSSGLDLSSEAT
LSDLAQTLASTAATPWHALPILADGSTDGVTREVLNPADHRDVVGTVTELKVEEAARVVAMAAEYAPQWAAVPPAERAAC
LDRAADIMQARIKVLMGIIMREAGKSAANAVGEVREAVDFLRYYADQARKTLGPSHLPLGPIVCISPWNFPLAIFTGQVA
AALVAGNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAQQTAGVMFTGSTEVARMIQAQLAERL
SATGKPIPLIAETGGQNGMIVDSSALAEQVVADVVTSAFDSAGQRCSALRVLCLQDDVADRTLAMLKGAFRELTIGRTDR
LSIDVGPVINDGAKAEIDQHIEAMRGAGRKVEQLPLPESAAKGTFVPPTIIEIKSLSDLTKEVFGPVLHVVRFKRNGLDR
LIDDINASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYIGRLVQRAPVP
PQQDSVHTDLALRDYIVWLDKKGLTDEGEAARGYASRSALGLERELTGPVGERNLYALHPRGRILLVPQTETGLYRQIAA
ALATGNHLAVDAGPLSKSVLAGLPAAVASRLSWTSDWEKDGPFSGALVEGDRDRVLAVNKKIAALPGPLLLVQAATTEEL
TSDPEAYCLNWLLEEVSTSINTAAAGGNASLMAIG
>Mature_1235_residues
MLNAAIDPTSSNDPAGGAPFAAFAPPVRPQSELRRAITAAYRRPETECLPPLVAAARVSEAKRYDIRSTARTLIEALRAK
HKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTDTRDALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTST
VNDRSLSAALTRLIARAGEPVIRRGVDMAMRMMGEQFVTGETIEEALKRARPLEARGFRYSYDMLGEAATTAADAERYFK
DYEKAIHAIGKASNGRGIYDGPGISIKLSALHPRYSRSQAGRVMGELLPKVKALAVLAKGYDIGLNIDAEEADRLELSLD
LLEELCFAPELAGWNGLGFVVQAYGKRCPFVLDYIIDLARRSGRRMMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIYT
DVAYIACARKLLAAADAVFPQFATHNAQTLATIYHLAGPDFGVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGT
HETLLAYLVRRLLENGANSSFVHRISDPNVSVEALIADPAETVAAMPVVGAPHVQIAAPKALYGSARANSSGLDLSSEAT
LSDLAQTLASTAATPWHALPILADGSTDGVTREVLNPADHRDVVGTVTELKVEEAARVVAMAAEYAPQWAAVPPAERAAC
LDRAADIMQARIKVLMGIIMREAGKSAANAVGEVREAVDFLRYYADQARKTLGPSHLPLGPIVCISPWNFPLAIFTGQVA
AALVAGNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAQQTAGVMFTGSTEVARMIQAQLAERL
SATGKPIPLIAETGGQNGMIVDSSALAEQVVADVVTSAFDSAGQRCSALRVLCLQDDVADRTLAMLKGAFRELTIGRTDR
LSIDVGPVINDGAKAEIDQHIEAMRGAGRKVEQLPLPESAAKGTFVPPTIIEIKSLSDLTKEVFGPVLHVVRFKRNGLDR
LIDDINASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYIGRLVQRAPVP
PQQDSVHTDLALRDYIVWLDKKGLTDEGEAARGYASRSALGLERELTGPVGERNLYALHPRGRILLVPQTETGLYRQIAA
ALATGNHLAVDAGPLSKSVLAGLPAAVASRLSWTSDWEKDGPFSGALVEGDRDRVLAVNKKIAALPGPLLLVQAATTEEL
TSDPEAYCLNWLLEEVSTSINTAAAGGNASLMAIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source, and also functions as a transcriptional repressor of its own gene [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=435, Percent_Identity=30.8045977011494, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI25777734, Length=435, Percent_Identity=30.8045977011494, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI238859541, Length=435, Percent_Identity=30.8045977011494, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI21361176, Length=468, Percent_Identity=28.6324786324786, Blast_Score=154, Evalue=6e-37,
Organism=Homo sapiens, GI12007648, Length=434, Percent_Identity=28.110599078341, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI25777724, Length=458, Percent_Identity=28.1659388646288, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI153266822, Length=471, Percent_Identity=27.8131634819533, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI25777732, Length=461, Percent_Identity=27.5488069414317, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI21614513, Length=422, Percent_Identity=27.7251184834123, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI25777728, Length=407, Percent_Identity=28.992628992629, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI238814322, Length=466, Percent_Identity=26.1802575107296, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI25777730, Length=477, Percent_Identity=26.4150943396226, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI4507229, Length=416, Percent_Identity=26.4423076923077, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI188035924, Length=454, Percent_Identity=26.2114537444934, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI310128103, Length=454, Percent_Identity=26.2114537444934, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI310128093, Length=454, Percent_Identity=26.2114537444934, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI25952152, Length=428, Percent_Identity=27.5700934579439, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI115387104, Length=465, Percent_Identity=27.0967741935484, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=27.972027972028, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI25777721, Length=429, Percent_Identity=25.6410256410256, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI25777726, Length=457, Percent_Identity=25.601750547046, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI310128091, Length=389, Percent_Identity=26.7352185089974, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI310128087, Length=275, Percent_Identity=27.6363636363636, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI4502043, Length=415, Percent_Identity=25.3012048192771, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI238814371, Length=415, Percent_Identity=25.3012048192771, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI71773324, Length=339, Percent_Identity=26.2536873156342, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI206597441, Length=332, Percent_Identity=25, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI206597439, Length=332, Percent_Identity=25, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI22907049, Length=332, Percent_Identity=25, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI73695881, Length=334, Percent_Identity=24.8502994011976, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI73695879, Length=334, Percent_Identity=24.8502994011976, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI310128101, Length=221, Percent_Identity=27.1493212669683, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI310128099, Length=221, Percent_Identity=27.1493212669683, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=25.6880733944954, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73466520, Length=335, Percent_Identity=22.9850746268657, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI4557303, Length=335, Percent_Identity=22.9850746268657, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI301500698, Length=282, Percent_Identity=25.886524822695, Blast_Score=76, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=1264, Percent_Identity=57.6740506329114, Blast_Score=1393, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=457, Percent_Identity=31.0722100656455, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1788042, Length=430, Percent_Identity=30.9302325581395, Blast_Score=156, Evalue=6e-39,
Organism=Escherichia coli, GI1787684, Length=463, Percent_Identity=29.5896328293737, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1787715, Length=454, Percent_Identity=28.6343612334802, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081896, Length=464, Percent_Identity=27.801724137931, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1787558, Length=412, Percent_Identity=30.5825242718447, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786504, Length=469, Percent_Identity=27.2921108742004, Blast_Score=126, Evalue=1e-29,
Organism=Escherichia coli, GI87082295, Length=420, Percent_Identity=27.3809523809524, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87081926, Length=378, Percent_Identity=25.3968253968254, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1787653, Length=258, Percent_Identity=24.031007751938, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=467, Percent_Identity=29.7644539614561, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=452, Percent_Identity=30.0884955752212, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17562198, Length=465, Percent_Identity=29.4623655913978, Blast_Score=147, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25144435, Length=462, Percent_Identity=29.8701298701299, Blast_Score=146, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI115532534, Length=337, Percent_Identity=32.3442136498516, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=465, Percent_Identity=27.3118279569892, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17534119, Length=461, Percent_Identity=27.765726681128, Blast_Score=139, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32564736, Length=413, Percent_Identity=30.2663438256659, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25143874, Length=427, Percent_Identity=26.6978922716628, Blast_Score=130, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25143876, Length=427, Percent_Identity=26.6978922716628, Blast_Score=130, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=409, Percent_Identity=27.8728606356968, Blast_Score=126, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=432, Percent_Identity=27.3148148148148, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71986308, Length=458, Percent_Identity=26.4192139737991, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17551164, Length=436, Percent_Identity=25.4587155963303, Blast_Score=113, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71995613, Length=389, Percent_Identity=26.7352185089974, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71990744, Length=320, Percent_Identity=27.5, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=335, Percent_Identity=25.9701492537313, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=330, Percent_Identity=23.9393939393939, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=330, Percent_Identity=23.9393939393939, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=330, Percent_Identity=23.9393939393939, Blast_Score=84, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=452, Percent_Identity=29.8672566371681, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321826, Length=475, Percent_Identity=28.4210526315789, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6325196, Length=462, Percent_Identity=31.1688311688312, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324950, Length=459, Percent_Identity=28.9760348583878, Blast_Score=157, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6323821, Length=502, Percent_Identity=29.6812749003984, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323822, Length=503, Percent_Identity=28.6282306163022, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319478, Length=457, Percent_Identity=27.1334792122538, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=23.6923076923077, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24668425, Length=504, Percent_Identity=29.9603174603175, Blast_Score=173, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24668417, Length=504, Percent_Identity=29.9603174603175, Blast_Score=173, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24668413, Length=504, Percent_Identity=29.9603174603175, Blast_Score=173, Evalue=8e-43,
Organism=Drosophila melanogaster, GI281362580, Length=504, Percent_Identity=29.9603174603175, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI62472918, Length=504, Percent_Identity=29.9603174603175, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI62472926, Length=504, Percent_Identity=29.9603174603175, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI62472936, Length=504, Percent_Identity=29.9603174603175, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI21356737, Length=504, Percent_Identity=29.9603174603175, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI20129399, Length=476, Percent_Identity=27.9411764705882, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24650465, Length=457, Percent_Identity=26.6958424507659, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24585660, Length=460, Percent_Identity=26.304347826087, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28574525, Length=443, Percent_Identity=29.1196388261851, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571806, Length=445, Percent_Identity=27.6404494382022, Blast_Score=130, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28571802, Length=445, Percent_Identity=27.6404494382022, Blast_Score=130, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28571800, Length=445, Percent_Identity=27.6404494382022, Blast_Score=130, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28571798, Length=445, Percent_Identity=27.6404494382022, Blast_Score=130, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28571796, Length=445, Percent_Identity=27.6404494382022, Blast_Score=130, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28571794, Length=445, Percent_Identity=27.6404494382022, Blast_Score=130, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24666674, Length=454, Percent_Identity=26.431718061674, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24638876, Length=375, Percent_Identity=28.2666666666667, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24638878, Length=375, Percent_Identity=28.2666666666667, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360299, Length=334, Percent_Identity=28.1437125748503, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281360297, Length=334, Percent_Identity=28.1437125748503, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281360295, Length=334, Percent_Identity=28.1437125748503, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24586250, Length=334, Percent_Identity=28.1437125748503, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281360301, Length=334, Percent_Identity=28.1437125748503, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45552499, Length=334, Percent_Identity=26.9461077844311, Blast_Score=91, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281360303, Length=334, Percent_Identity=26.9461077844311, Blast_Score=91, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 131640; Mature: 131640

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAAIDPTSSNDPAGGAPFAAFAPPVRPQSELRRAITAAYRRPETECLPPLVAAARVSE
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHH
AKRYDIRSTARTLIEALRAKHKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTDTRD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHH
ALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRSLSAALTRLIARAGEP
HHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEEECCHHCCCCHHHHHHHHHHHHHHCCCH
VIRRGVDMAMRMMGEQFVTGETIEEALKRARPLEARGFRYSYDMLGEAATTAADAERYFK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
DYEKAIHAIGKASNGRGIYDGPGISIKLSALHPRYSRSQAGRVMGELLPKVKALAVLAKG
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YDIGLNIDAEEADRLELSLDLLEELCFAPELAGWNGLGFVVQAYGKRCPFVLDYIIDLAR
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
RSGRRMMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIYTDVAYIACARKLLAAADAVFP
HCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFATHNAQTLATIYHLAGPDFGVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGT
HHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHCHHHCCCCEEEEECCCC
HETLLAYLVRRLLENGANSSFVHRISDPNVSVEALIADPAETVAAMPVVGAPHVQIAAPK
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCCCCCEEEECCH
ALYGSARANSSGLDLSSEATLSDLAQTLASTAATPWHALPILADGSTDGVTREVLNPADH
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCC
RDVVGTVTELKVEEAARVVAMAAEYAPQWAAVPPAERAACLDRAADIMQARIKVLMGIIM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSAANAVGEVREAVDFLRYYADQARKTLGPSHLPLGPIVCISPWNFPLAIFTGQVA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEHHHHHH
AALVAGNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAQQTAGV
HHHHCCCCCEECCCCCCCEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHCCE
MFTGSTEVARMIQAQLAERLSATGKPIPLIAETGGQNGMIVDSSALAEQVVADVVTSAFD
EEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHH
SAGQRCSALRVLCLQDDVADRTLAMLKGAFRELTIGRTDRLSIDVGPVINDGAKAEIDQH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHH
IEAMRGAGRKVEQLPLPESAAKGTFVPPTIIEIKSLSDLTKEVFGPVLHVVRFKRNGLDR
HHHHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LIDDINASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGT
HHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCCCCCCC
GPKAGGPLYIGRLVQRAPVPPQQDSVHTDLALRDYIVWLDKKGLTDEGEAARGYASRSAL
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCHHHCHHHHHHC
GLERELTGPVGERNLYALHPRGRILLVPQTETGLYRQIAAALATGNHLAVDAGPLSKSVL
CCHHHCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHH
AGLPAAVASRLSWTSDWEKDGPFSGALVEGDRDRVLAVNKKIAALPGPLLLVQAATTEEL
HCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHHHCCCCEEEEEECCHHHH
TSDPEAYCLNWLLEEVSTSINTAAAGGNASLMAIG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MLNAAIDPTSSNDPAGGAPFAAFAPPVRPQSELRRAITAAYRRPETECLPPLVAAARVSE
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHH
AKRYDIRSTARTLIEALRAKHKGTGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTDTRD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHH
ALIRDKIAEGNWTSHIGGGKSMFVNAATWGLVVTGKLTSTVNDRSLSAALTRLIARAGEP
HHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEEECCHHCCCCHHHHHHHHHHHHHHCCCH
VIRRGVDMAMRMMGEQFVTGETIEEALKRARPLEARGFRYSYDMLGEAATTAADAERYFK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
DYEKAIHAIGKASNGRGIYDGPGISIKLSALHPRYSRSQAGRVMGELLPKVKALAVLAKG
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YDIGLNIDAEEADRLELSLDLLEELCFAPELAGWNGLGFVVQAYGKRCPFVLDYIIDLAR
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
RSGRRMMVRLVKGAYWDAEIKRAQLDGLDDYPVYTRKIYTDVAYIACARKLLAAADAVFP
HCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFATHNAQTLATIYHLAGPDFGVGKYEFQCLHGMGEPLYDEVVGKEKLDRPCRIYAPVGT
HHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHCHHHCCCCEEEEECCCC
HETLLAYLVRRLLENGANSSFVHRISDPNVSVEALIADPAETVAAMPVVGAPHVQIAAPK
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCCCCCEEEECCH
ALYGSARANSSGLDLSSEATLSDLAQTLASTAATPWHALPILADGSTDGVTREVLNPADH
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCC
RDVVGTVTELKVEEAARVVAMAAEYAPQWAAVPPAERAACLDRAADIMQARIKVLMGIIM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSAANAVGEVREAVDFLRYYADQARKTLGPSHLPLGPIVCISPWNFPLAIFTGQVA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEHHHHHH
AALVAGNPVLAKPAGVTPIIASESVKILHEAGVPVGALQFVPGSGRLGAGMVGAQQTAGV
HHHHCCCCCEECCCCCCCEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHCCE
MFTGSTEVARMIQAQLAERLSATGKPIPLIAETGGQNGMIVDSSALAEQVVADVVTSAFD
EEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHH
SAGQRCSALRVLCLQDDVADRTLAMLKGAFRELTIGRTDRLSIDVGPVINDGAKAEIDQH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHH
IEAMRGAGRKVEQLPLPESAAKGTFVPPTIIEIKSLSDLTKEVFGPVLHVVRFKRNGLDR
HHHHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LIDDINASGYGLTFGLHTRLDETIAHVTSRIKAGNLYVNRNIIGAVVGVQPFGGRGLSGT
HHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCCCCCCC
GPKAGGPLYIGRLVQRAPVPPQQDSVHTDLALRDYIVWLDKKGLTDEGEAARGYASRSAL
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCHHHCHHHHHHC
GLERELTGPVGERNLYALHPRGRILLVPQTETGLYRQIAAALATGNHLAVDAGPLSKSVL
CCHHHCCCCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHH
AGLPAAVASRLSWTSDWEKDGPFSGALVEGDRDRVLAVNKKIAALPGPLLLVQAATTEEL
HCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHHHCCCCEEEEEECCHHHH
TSDPEAYCLNWLLEEVSTSINTAAAGGNASLMAIG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004223; 10715000 [H]