BacMap

Definition	Rhizobium etli CFN 42 plasmid p42f, complete sequence.
Accession	NC_007766
Length	642,517

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The map label for this gene is rdh

Identifier: 86360739

GI number: 86360739

Start: 6055

End: 6780

Strand: Direct

Name: rdh

Synonym: RHE_PF00005

Alternate gene names: 86360739

Gene position: 6055-6780 (Clockwise)

Preceding gene: 86360738

Following gene: 86360740

Centisome position: 0.94

GC content: 62.12

Gene sequence:

>726_bases
ATGAACGGTTTGCAAGGCAAAGTCGCGGCCATTACCGGAGCTGCCTCGGGCATTGGATTGGCGTCGACAGAAGCGATCAT
CGCGGCGGGCGGTACCGTCGTGATGATAGACCGGGACGAGGCGGCGCTGGACGCGGCCTGCGGCCGGCTGGGAGAAAGGG
CGATCGCGCTGCCGCTCGACCTTCTCAAACCCGAGGATTGCGCCGGCCTGCTTGACGGCATTCTCGCCAAGGTCGGTCAG
CTCGACATCTTCCACGCCAATGCCGGCACCTATATCGGCGGAGATCTGGTGGATGCAAACCTCGACGCGATCGACCGCAT
GCTCAATCTGAACGTGAACGTGGTCATAAAGAACGTCCGCACGGTCATGCCCCACATGATCGGAAGAGGGACGGGAGATA
TCATCGTCACCAGTTCGGTCGCGGGCCAAGCCGCGGTTCCATGGGAGCCGGTCTACTCCCCTTCGAAATGGGCGATGCAT
TGCTTCGTCCAGACCATGCGGCGGCAGCTCCTGAAAAACGGAATCCGCGTCGGATCCGTCTCGCCAGGCCCTGTCAGCAG
CGCGCTGCTGAAAGACTGGCCGGAGGAAAACCTGCGCAAGGCAAAAGAGGCGGGCGCGTTGATCGAACCGCGAGACGTCG
CCGAAGCCGTGCTCTTCATGCTGACCCGGCCACGCAACGTGACGATCCGCGACATGGTGATCCTGCCGAGCTCCTTCGAC
ATTTAG

Upstream 100 bases:

>100_bases
CCAGCTCCCGATCGTTCAGGCCGTCGATGCAGCATCGCAGACTTCTAGCCACGACCGACCTCACATGCGATAGGTAATGG
ATACATTTGGAGGAGTGGAC

Downstream 100 bases:

>100_bases
CTTGAGCGGGAGGCAGAGCGCACTCCTTCCGCACAAGCTGACTGCGGGAGGATGTGGACAGGCGTGCCGTGTGGGTGCCA
CACGGCACCCTATCCACTTT

Product: ribitol 2-dehydrogenase protein

Products: NA

Alternate protein names: RDH [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNGLQGKVAAITGAASGIGLASTEAIIAAGGTVVMIDRDEAALDAACGRLGERAIALPLDLLKPEDCAGLLDGILAKVGQ
LDIFHANAGTYIGGDLVDANLDAIDRMLNLNVNVVIKNVRTVMPHMIGRGTGDIIVTSSVAGQAAVPWEPVYSPSKWAMH
CFVQTMRRQLLKNGIRVGSVSPGPVSSALLKDWPEENLRKAKEAGALIEPRDVAEAVLFMLTRPRNVTIRDMVILPSSFD
I

Sequences:

>Translated_241_residues
MNGLQGKVAAITGAASGIGLASTEAIIAAGGTVVMIDRDEAALDAACGRLGERAIALPLDLLKPEDCAGLLDGILAKVGQ
LDIFHANAGTYIGGDLVDANLDAIDRMLNLNVNVVIKNVRTVMPHMIGRGTGDIIVTSSVAGQAAVPWEPVYSPSKWAMH
CFVQTMRRQLLKNGIRVGSVSPGPVSSALLKDWPEENLRKAKEAGALIEPRDVAEAVLFMLTRPRNVTIRDMVILPSSFD
I
>Mature_241_residues
MNGLQGKVAAITGAASGIGLASTEAIIAAGGTVVMIDRDEAALDAACGRLGERAIALPLDLLKPEDCAGLLDGILAKVGQ
LDIFHANAGTYIGGDLVDANLDAIDRMLNLNVNVVIKNVRTVMPHMIGRGTGDIIVTSSVAGQAAVPWEPVYSPSKWAMH
CFVQTMRRQLLKNGIRVGSVSPGPVSSALLKDWPEENLRKAKEAGALIEPRDVAEAVLFMLTRPRNVTIRDMVILPSSFD
I

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=218, Percent_Identity=28.8990825688073, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI109715829, Length=251, Percent_Identity=28.2868525896414, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=31.0880829015544, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI142976729, Length=243, Percent_Identity=24.6913580246914, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI210032110, Length=242, Percent_Identity=25.6198347107438, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI31542939, Length=221, Percent_Identity=28.5067873303167, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=25.7261410788382, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=32.7956989247312, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7705925, Length=228, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7705855, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI223718074, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=235, Percent_Identity=30.2127659574468, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787335, Length=220, Percent_Identity=27.7272727272727, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=25.6410256410256, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=225, Percent_Identity=27.1111111111111, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787905, Length=226, Percent_Identity=29.646017699115, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=202, Percent_Identity=28.2178217821782, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=250, Percent_Identity=28.8, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=241, Percent_Identity=26.5560165975104, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=246, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=252, Percent_Identity=30.1587301587302, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=250, Percent_Identity=27.2, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=247, Percent_Identity=29.9595141700405, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=249, Percent_Identity=28.9156626506024, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=244, Percent_Identity=28.2786885245902, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=244, Percent_Identity=27.4590163934426, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=244, Percent_Identity=27.4590163934426, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=246, Percent_Identity=26.4227642276423, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=230, Percent_Identity=28.695652173913, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=237, Percent_Identity=27.0042194092827, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=24.8979591836735, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=244, Percent_Identity=27.0491803278689, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=244, Percent_Identity=26.2295081967213, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=243, Percent_Identity=27.1604938271605, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=194, Percent_Identity=29.8969072164948, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=252, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=25.7731958762887, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=227, Percent_Identity=26.431718061674, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=27.1255060728745, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322067, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=235, Percent_Identity=31.063829787234, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357041, Length=233, Percent_Identity=29.1845493562232, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281364494, Length=250, Percent_Identity=30.4, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571526, Length=241, Percent_Identity=29.045643153527, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641232, Length=251, Percent_Identity=28.6852589641434, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571387, Length=247, Percent_Identity=28.7449392712551, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24663911, Length=245, Percent_Identity=28.9795918367347, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007236, Length=244, Percent_Identity=26.6393442622951, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24648944, Length=242, Percent_Identity=29.7520661157025, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644339, Length=230, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=26.6009852216749, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355319, Length=202, Percent_Identity=29.2079207920792, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648693, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355889, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=26.2135922330097, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644337, Length=230, Percent_Identity=30, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641388, Length=259, Percent_Identity=26.2548262548263, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=25.6, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=224, Percent_Identity=25.4464285714286, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.56 [H]

Molecular weight: Translated: 25474; Mature: 25474

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLQGKVAAITGAASGIGLASTEAIIAAGGTVVMIDRDEAALDAACGRLGERAIALPLD
CCCCCCEEEEEECCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHCCCEEECCHH
LLKPEDCAGLLDGILAKVGQLDIFHANAGTYIGGDLVDANLDAIDRMLNLNVNVVIKNVR
HCCCCHHHHHHHHHHHHHCCEEEEECCCCCEECCCEECCCHHHHHHHHCCCCEEEEHHHH
TVMPHMIGRGTGDIIVTSSVAGQAAVPWEPVYSPSKWAMHCFVQTMRRQLLKNGIRVGSV
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCC
SPGPVSSALLKDWPEENLRKAKEAGALIEPRDVAEAVLFMLTRPRNVTIRDMVILPSSFD
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
I
C
>Mature Secondary Structure
MNGLQGKVAAITGAASGIGLASTEAIIAAGGTVVMIDRDEAALDAACGRLGERAIALPLD
CCCCCCEEEEEECCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHCCCEEECCHH
LLKPEDCAGLLDGILAKVGQLDIFHANAGTYIGGDLVDANLDAIDRMLNLNVNVVIKNVR
HCCCCHHHHHHHHHHHHHCCEEEEECCCCCEECCCEECCCHHHHHHHHCCCCEEEEHHHH
TVMPHMIGRGTGDIIVTSSVAGQAAVPWEPVYSPSKWAMHCFVQTMRRQLLKNGIRVGSV
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCC
SPGPVSSALLKDWPEENLRKAKEAGALIEPRDVAEAVLFMLTRPRNVTIRDMVILPSSFD
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3904726; 2933028; 3891331 [H]