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The map label for this gene is xcpR [H]

Identifier: 85860073

GI number: 85860073

Start: 2282134

End: 2283798

Strand: Direct

Name: xcpR [H]

Synonym: SYN_01549

Alternate gene names: 85860073

Gene position: 2282134-2283798 (Clockwise)

Preceding gene: 85860072

Following gene: 85860074

Centisome position: 71.78

GC content: 53.75

Gene sequence:

>1665_bases
ATGACGATTACCCCAGAACTTGCCACACCTCATTCCATGGATAATGAAGTCCATCTCAATCCGGAAGAAGAAAAAATTGT
CACCCAGGCCCAGGCATTGAATCTTCCCTTCTGGAGAGAAATGCCGACGGAGATCGCGGGTGTCGGATTCAACGGCCAGG
TTCCTGTTCAATTCCTGAAGCGTCACAAGATCGTCCCCCTGGAAGCACATTCCTCCACGGTTATCGCGGTCAACAATCCT
GCTTTCTTCGAACCCATCGACGACCTGAAGCGACTGCTGCAGAATCCGGATATCTCCATCGTTCTCGCTCCCGAATCCGC
CATCCTTTTCGCCATCAAGCAGCTTTATGAACACGACCGCAGCACAGTGGAGGCCTTTGTCCAGACCTTCATGGATGACT
CCTATGACCGGATTCTTTCAGAAATCGAAGAAACGGGGGATATTCTGGATGATGCGCACGAAGCGCCCATGATCCAGCTG
GTCAACCTGATTCTCTCCCGGGCGATCCGGGACCGGGCCAGTGATATTCACATCGAACCCTATCAGAATTCCCTGAAGAT
CCGGTATCGAATCGATGGAATGCTCAGCATTGCCATGGACCTGCCGCGCAAGGTGCACGCCGCCCTCGTTTCCCGTATCA
AAATCATGGCCAGACTGGATATCGCGGAAAAGCGGCTTCCCCAGGATGGCCGTATCGATGCCAGGATCGGGAACCGAAGC
GTGGATGTTCGAGTTTCCGTACTGCCGACGGCCTTCGGCGAACGTCTGGTTCTGCGCCTGCTGGACAAGACGCGCGCGCT
GCTGCAATTGCCCGATCTTGGGTTCAATCCGCAAACAATAGGAATTTTCAACCGTCTGATTTCATCCCCCTATGGGATTA
TTCTGGTAACCGGACCAACGGGAAGCGGCAAAACGACAACCCTTTACGCCCTCCTTTCCAATCTCAACAATTCGGAAATC
AACATCATCACCATCGAAGACCCCATTGAATATCAGATTGACGGCATCGCCCAGATTCAGATCAACCCGAAAATTGATCT
CTCGTTCGCCAACGGTCTGCGTTCCATCGTCCGGCAGGACCCCGATGTCATTCTTGTGGGAGAAGTCAGGGATAAAGAAA
CAGCGGAAATAGCCATTCAATCGTCGCTTACCGGTCACCTGGTCCTCTCCACGCTCCATACCAACGATGCCGCCAGTGCG
GTGACCCGCCTGATTGACATGGAAATCGAACCTTTTCTCATTACCTCATCGGTAATCGCCATCGTTGCTCAGCGGCTGGT
CCGTGTCCTCTGCCCGCAGTGCAGACAGCCCTATATCCCGGACAGACAATCTTTAACCAATATCGGCCTGTCTCCGGAAA
TGGCGGAGAACGCGACGATTTACAGAAAGGGCGGCTGTTCAGCCTGCATGAACACCGGCTACCACGGCAGAACAGCCATT
ATGGAACTCATGGTGATGGAGGAATCGCTGAAGCACATGATCCTGAAAACATCGGATTCCAACGCGATTCACCAGGAAGC
CGTGGAATGCGGGATGCTGCCTCTGCTCCAGGACGGCGCCCACAAGGTTCTGGAAGGGATCACAACCATAGAAGAAGTAC
TCCGGGTCACACGCGTTTTGAAAACCCGCTCACGCAAGCGGACGGCCTCTCATCCCGGTGCATGA

Upstream 100 bases:

>100_bases
CAGATGCCAGCCGGATATCCAAGGAAAAAAGCGACCATCTGGAAAGGGAGAAGAAAAATCTCTCCAACCCTGGTCAGAAG
AAAGGAAACCACTGATATAA

Downstream 100 bases:

>100_bases
AGAAATACCCCTTTTGCTCAGTTATTCCAGTTTCAGATCAGAGATGATATCGAGGCGACAAGGCAGAGGCGCACAGACGT
GCCGAAGCGCACGTCGAGGA

Product: general secretion pathway protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MTITPELATPHSMDNEVHLNPEEEKIVTQAQALNLPFWREMPTEIAGVGFNGQVPVQFLKRHKIVPLEAHSSTVIAVNNP
AFFEPIDDLKRLLQNPDISIVLAPESAILFAIKQLYEHDRSTVEAFVQTFMDDSYDRILSEIEETGDILDDAHEAPMIQL
VNLILSRAIRDRASDIHIEPYQNSLKIRYRIDGMLSIAMDLPRKVHAALVSRIKIMARLDIAEKRLPQDGRIDARIGNRS
VDVRVSVLPTAFGERLVLRLLDKTRALLQLPDLGFNPQTIGIFNRLISSPYGIILVTGPTGSGKTTTLYALLSNLNNSEI
NIITIEDPIEYQIDGIAQIQINPKIDLSFANGLRSIVRQDPDVILVGEVRDKETAEIAIQSSLTGHLVLSTLHTNDAASA
VTRLIDMEIEPFLITSSVIAIVAQRLVRVLCPQCRQPYIPDRQSLTNIGLSPEMAENATIYRKGGCSACMNTGYHGRTAI
MELMVMEESLKHMILKTSDSNAIHQEAVECGMLPLLQDGAHKVLEGITTIEEVLRVTRVLKTRSRKRTASHPGA

Sequences:

>Translated_554_residues
MTITPELATPHSMDNEVHLNPEEEKIVTQAQALNLPFWREMPTEIAGVGFNGQVPVQFLKRHKIVPLEAHSSTVIAVNNP
AFFEPIDDLKRLLQNPDISIVLAPESAILFAIKQLYEHDRSTVEAFVQTFMDDSYDRILSEIEETGDILDDAHEAPMIQL
VNLILSRAIRDRASDIHIEPYQNSLKIRYRIDGMLSIAMDLPRKVHAALVSRIKIMARLDIAEKRLPQDGRIDARIGNRS
VDVRVSVLPTAFGERLVLRLLDKTRALLQLPDLGFNPQTIGIFNRLISSPYGIILVTGPTGSGKTTTLYALLSNLNNSEI
NIITIEDPIEYQIDGIAQIQINPKIDLSFANGLRSIVRQDPDVILVGEVRDKETAEIAIQSSLTGHLVLSTLHTNDAASA
VTRLIDMEIEPFLITSSVIAIVAQRLVRVLCPQCRQPYIPDRQSLTNIGLSPEMAENATIYRKGGCSACMNTGYHGRTAI
MELMVMEESLKHMILKTSDSNAIHQEAVECGMLPLLQDGAHKVLEGITTIEEVLRVTRVLKTRSRKRTASHPGA
>Mature_553_residues
TITPELATPHSMDNEVHLNPEEEKIVTQAQALNLPFWREMPTEIAGVGFNGQVPVQFLKRHKIVPLEAHSSTVIAVNNPA
FFEPIDDLKRLLQNPDISIVLAPESAILFAIKQLYEHDRSTVEAFVQTFMDDSYDRILSEIEETGDILDDAHEAPMIQLV
NLILSRAIRDRASDIHIEPYQNSLKIRYRIDGMLSIAMDLPRKVHAALVSRIKIMARLDIAEKRLPQDGRIDARIGNRSV
DVRVSVLPTAFGERLVLRLLDKTRALLQLPDLGFNPQTIGIFNRLISSPYGIILVTGPTGSGKTTTLYALLSNLNNSEIN
IITIEDPIEYQIDGIAQIQINPKIDLSFANGLRSIVRQDPDVILVGEVRDKETAEIAIQSSLTGHLVLSTLHTNDAASAV
TRLIDMEIEPFLITSSVIAIVAQRLVRVLCPQCRQPYIPDRQSLTNIGLSPEMAENATIYRKGGCSACMNTGYHGRTAIM
ELMVMEESLKHMILKTSDSNAIHQEAVECGMLPLLQDGAHKVLEGITTIEEVLRVTRVLKTRSRKRTASHPGA

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=417, Percent_Identity=52.5179856115108, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1786296, Length=444, Percent_Identity=38.963963963964, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI87082188, Length=276, Percent_Identity=36.5942028985507, Blast_Score=128, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 61601; Mature: 61470

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITPELATPHSMDNEVHLNPEEEKIVTQAQALNLPFWREMPTEIAGVGFNGQVPVQFLK
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCCCHHHHHH
RHKIVPLEAHSSTVIAVNNPAFFEPIDDLKRLLQNPDISIVLAPESAILFAIKQLYEHDR
CCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
STVEAFVQTFMDDSYDRILSEIEETGDILDDAHEAPMIQLVNLILSRAIRDRASDIHIEP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEE
YQNSLKIRYRIDGMLSIAMDLPRKVHAALVSRIKIMARLDIAEKRLPQDGRIDARIGNRS
CCCCEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCE
VDVRVSVLPTAFGERLVLRLLDKTRALLQLPDLGFNPQTIGIFNRLISSPYGIILVTGPT
EEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GSGKTTTLYALLSNLNNSEINIITIEDPIEYQIDGIAQIQINPKIDLSFANGLRSIVRQD
CCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCEEEEEECCCEEEHHHHHHHHHHHCC
PDVILVGEVRDKETAEIAIQSSLTGHLVLSTLHTNDAASAVTRLIDMEIEPFLITSSVIA
CCEEEEECCCCCCHHHEEEECCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHH
IVAQRLVRVLCPQCRQPYIPDRQSLTNIGLSPEMAENATIYRKGGCSACMNTGYHGRTAI
HHHHHHHHHHCHHHCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCHHHHCCCCCHHHHH
MELMVMEESLKHMILKTSDSNAIHQEAVECGMLPLLQDGAHKVLEGITTIEEVLRVTRVL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTRSRKRTASHPGA
HHHHHHHCCCCCCC
>Mature Secondary Structure 
TITPELATPHSMDNEVHLNPEEEKIVTQAQALNLPFWREMPTEIAGVGFNGQVPVQFLK
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCCCHHHHHH
RHKIVPLEAHSSTVIAVNNPAFFEPIDDLKRLLQNPDISIVLAPESAILFAIKQLYEHDR
CCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
STVEAFVQTFMDDSYDRILSEIEETGDILDDAHEAPMIQLVNLILSRAIRDRASDIHIEP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEE
YQNSLKIRYRIDGMLSIAMDLPRKVHAALVSRIKIMARLDIAEKRLPQDGRIDARIGNRS
CCCCEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCE
VDVRVSVLPTAFGERLVLRLLDKTRALLQLPDLGFNPQTIGIFNRLISSPYGIILVTGPT
EEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GSGKTTTLYALLSNLNNSEINIITIEDPIEYQIDGIAQIQINPKIDLSFANGLRSIVRQD
CCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCEEEEEECCCEEEHHHHHHHHHHHCC
PDVILVGEVRDKETAEIAIQSSLTGHLVLSTLHTNDAASAVTRLIDMEIEPFLITSSVIA
CCEEEEECCCCCCHHHEEEECCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHH
IVAQRLVRVLCPQCRQPYIPDRQSLTNIGLSPEMAENATIYRKGGCSACMNTGYHGRTAI
HHHHHHHHHHCHHHCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCHHHHCCCCCHHHHH
MELMVMEESLKHMILKTSDSNAIHQEAVECGMLPLLQDGAHKVLEGITTIEEVLRVTRVL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTRSRKRTASHPGA
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]