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The map label for this gene is pyrR [H]

Identifier: 85860055

GI number: 85860055

Start: 2266865

End: 2267410

Strand: Direct

Name: pyrR [H]

Synonym: SYN_03702

Alternate gene names: 85860055

Gene position: 2266865-2267410 (Clockwise)

Preceding gene: 85860052

Following gene: 85860056

Centisome position: 71.3

GC content: 49.27

Gene sequence:

>546_bases
ATGATGACACCCAAAAAAGTGGTCATGGATGCAGCGGAAATCGACCGATCTTTGACCCGGATCGCCTATGAAATCCTGGA
AAAAAACAAGGGCGTAGAAGATCTGGTTCTTGTGGGCATCAGAACCGGCGGTGTTTTTCTCGCGGAACGGCTCAGGAGAA
AGATTCTTGATATCGAGGGCGCGGAAGTTCCTTGCGGCATTCTGGATATTACTCTTTATCGCGATGATCTTCTTTTGGCG
AATAAAAAGCCCAAGATAAAAAAAACGGACATCCCTTTCTCTCTTGATAAGAAGAAAGTGATCCTTGTCGACGATGTTCT
CTTTACCGGCCGAACGATCCGGGCGGCCATGGATGCCCTTATTGACTTTGGCCGTCCCAGGTCGATTCAGCTTGCCGTCC
TGATTGACAGAGGCCATCGTGAACTGCCGATACGCGCTGATTTTGTCGGCGAGAATCTTCCCTCTCTTCTCTGGGAGGAC
ATCAGTGTCAACCTGATTGAAAAAAACGGCTGCGATGAAGTGGTCATTGAGGACAGCGGCCATTAG

Upstream 100 bases:

>100_bases
AATGGGAAGGCTTTTTTGTTGAACAGCCTGAGCTTCATATGAGCGACCGAAATTTCGTGCACCTTTCTCACCTGAAACAC
TGAGTACATAAAAGGAACAG

Downstream 100 bases:

>100_bases
AATGCATCACTTGCATGCATCTGCCGCCAGGTCTCTGTTCCAGGGGTTTTGCAATGAAATGGGAACGTAAGGACATTCTG
GGCATGAAAGATCTTTCCGT

Product: uracil phosphoribosyltransferase / pyrimidine operon regulatory protein

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MMTPKKVVMDAAEIDRSLTRIAYEILEKNKGVEDLVLVGIRTGGVFLAERLRRKILDIEGAEVPCGILDITLYRDDLLLA
NKKPKIKKTDIPFSLDKKKVILVDDVLFTGRTIRAAMDALIDFGRPRSIQLAVLIDRGHRELPIRADFVGENLPSLLWED
ISVNLIEKNGCDEVVIEDSGH

Sequences:

>Translated_181_residues
MMTPKKVVMDAAEIDRSLTRIAYEILEKNKGVEDLVLVGIRTGGVFLAERLRRKILDIEGAEVPCGILDITLYRDDLLLA
NKKPKIKKTDIPFSLDKKKVILVDDVLFTGRTIRAAMDALIDFGRPRSIQLAVLIDRGHRELPIRADFVGENLPSLLWED
ISVNLIEKNGCDEVVIEDSGH
>Mature_181_residues
MMTPKKVVMDAAEIDRSLTRIAYEILEKNKGVEDLVLVGIRTGGVFLAERLRRKILDIEGAEVPCGILDITLYRDDLLLA
NKKPKIKKTDIPFSLDKKKVILVDDVLFTGRTIRAAMDALIDFGRPRSIQLAVLIDRGHRELPIRADFVGENLPSLLWED
ISVNLIEKNGCDEVVIEDSGH

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20318; Mature: 20318

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTPKKVVMDAAEIDRSLTRIAYEILEKNKGVEDLVLVGIRTGGVFLAERLRRKILDIEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
AEVPCGILDITLYRDDLLLANKKPKIKKTDIPFSLDKKKVILVDDVLFTGRTIRAAMDAL
CCCCCCEEEEEEECCCEEEECCCCCCEECCCCCCCCCCEEEEEECHHHCCHHHHHHHHHH
IDFGRPRSIQLAVLIDRGHRELPIRADFVGENLPSLLWEDISVNLIEKNGCDEVVIEDSG
HHCCCCCCEEEEEEEECCCCCCCEEHHHCCCCHHHHHHHCCEEEEEECCCCCEEEEECCC
H
C
>Mature Secondary Structure
MMTPKKVVMDAAEIDRSLTRIAYEILEKNKGVEDLVLVGIRTGGVFLAERLRRKILDIEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
AEVPCGILDITLYRDDLLLANKKPKIKKTDIPFSLDKKKVILVDDVLFTGRTIRAAMDAL
CCCCCCEEEEEEECCCEEEECCCCCCEECCCCCCCCCCEEEEEECHHHCCHHHHHHHHHH
IDFGRPRSIQLAVLIDRGHRELPIRADFVGENLPSLLWEDISVNLIEKNGCDEVVIEDSG
HHCCCCCCEEEEEEEECCCCCCCEEHHHCCCCHHHHHHHCCEEEEEECCCCCEEEEECCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA