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The map label for this gene is aceF [C]

Identifier: 85859864

GI number: 85859864

Start: 2097218

End: 2097427

Strand: Direct

Name: aceF [C]

Synonym: SYN_00479

Alternate gene names: 85859864

Gene position: 2097218-2097427 (Clockwise)

Preceding gene: 85859862

Following gene: 85859865

Centisome position: 65.96

GC content: 50.48

Gene sequence:

>210_bases
ATGGAAGTCACTGTACCCATGGAAGGAAAGGTTGTAGCAATCAAAGTTAATGTCGGCGACAAGGTTGAAGAAGACGACGA
AATCGCGGTCATGGAAGCCATGAAGATGGAAATGCCTGTCCCGTCGCCGGTCAGCGGCGTCGTAAAACAAATCATGGTCA
AGGTTGGTGACAAGGTTGCGGCTGAGGCTGCGTTGATGGTCATCGAATAG

Upstream 100 bases:

>100_bases
TGATGGCAGTCAACCAGCTTTATAGATAGTGGGTTTCCGTTGCCGAAAGGGATGGGCCCTGGCAGTTAAAATTCATCAAA
AGAAACTGTAGGAGGAAATT

Downstream 100 bases:

>100_bases
ATCAGATTTTCCAGATATTACACACCAAAGAAACAAGAAAACACCCCATACCGATCTTTACAAAGTGGTTCAGCCGCTTC
AAAATGCAGGATATTCAATG

Product: biotin carboxyl carrier protein of glutaconyl-CoA decarboxylase

Products: pyruvate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 69; Mature: 69

Protein sequence:

>69_residues
MEVTVPMEGKVVAIKVNVGDKVEEDDEIAVMEAMKMEMPVPSPVSGVVKQIMVKVGDKVAAEAALMVIE

Sequences:

>Translated_69_residues
MEVTVPMEGKVVAIKVNVGDKVEEDDEIAVMEAMKMEMPVPSPVSGVVKQIMVKVGDKVAAEAALMVIE
>Mature_69_residues
MEVTVPMEGKVVAIKVNVGDKVEEDDEIAVMEAMKMEMPVPSPVSGVVKQIMVKVGDKVAAEAALMVIE

Specific function: The Pyruvate Dehydrogenase Complex Catalyzes The Overall Conversion Of Pyruvate To Acetyl-CoA And Co(2). It Contains Multiple Copies Of Three Enzymatic Components: Pyruvate Dehydrogenase (E1), Dihydrolipoamide Acetyltransferase (E2) And Lipoamide Dehydrog

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Drosophila melanogaster, GI24652212, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652210, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652214, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19921944, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652216, Length=68, Percent_Identity=50, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363050, Length=68, Percent_Identity=50, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652224, Length=68, Percent_Identity=50, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652222, Length=68, Percent_Identity=50, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652220, Length=68, Percent_Identity=50, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652218, Length=68, Percent_Identity=50, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 912 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.1.3

Molecular weight: Translated: 7371; Mature: 7371

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
11.6 %Met     (Translated Protein)
11.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
11.6 %Met     (Mature Protein)
11.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTVPMEGKVVAIKVNVGDKVEEDDEIAVMEAMKMEMPVPSPVSGVVKQIMVKVGDKVA
CEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
AEAALMVIE
CCEEEEEEC
>Mature Secondary Structure
MEVTVPMEGKVVAIKVNVGDKVEEDDEIAVMEAMKMEMPVPSPVSGVVKQIMVKVGDKVA
CEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
AEAALMVIE
CCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: oxaloacetate

Specific reaction: oxaloacetate = pyruvate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA