BacMap

Definition	Syntrophus aciditrophicus SB chromosome, complete genome.
Accession	NC_007759
Length	3,179,300

Click here to switch to the map view.

The map label for this gene is paaF [C]

Identifier: 85859760

GI number: 85859760

Start: 1995851

End: 1996651

Strand: Direct

Name: paaF [C]

Synonym: SYN_01309

Alternate gene names: 85859760

Gene position: 1995851-1996651 (Clockwise)

Preceding gene: 85859759

Following gene: 85859762

Centisome position: 62.78

GC content: 54.68

Gene sequence:

>801_bases
GTGACAGGGGGACAAAATCTCATGGCATATGAAACGATACTCCTCAAAATCGAGGGTAATATTGCAACGATAACGATCAA
TCGCCCCCCCATGAATCCCCTGAACAGCGGAGTTTTCCGGGATGTCATTGCGGCCACTCGAGAAATCGAAGCCGACGATA
ATGTCAAGGTCATCATTCTGGACAGCACCGGAGACAAGGCTTTCGCCGCCGGCGCCGACGTCAAGGAAATGGTTAATTTG
ACGCCGGTCGAGATCTACGATTTCAGCCTGAACTTCCGCAAGGCCTGTGAATGTTTTGCAGCCAATCCGCTTCCTACGAT
TGCCGTCATCAAGGGATTCGCCCTTGGAGGCGGCTGCGAAATGGCCATGGCCTGTGACCTTAGAATCGCTGCCGACAACG
CAAAATTCGGTCAGCCGGAAATTAATCTGGGTGTGACTCCCGGAGCGGGCGGTACGCAGAGGTTGACCCGTCTGGTCGGC
GCTGCCCGGGCCAAGGAGCTGATCCTTACGGGCGACATGATCGACGCGGCAACAGCGGAGAGAATCGGCCTCGTAAATAA
AGTCGTGCCTCTGGCGGAACTGGATGCCGCTGTGGCCGCCCTGGCGGAGAAACTGGCGTCCAAACCGAAAGTCAGCCTGA
AACTGTGCAAATCCGCGATCAACACGGCAGAGGATGTCGACATCAGCAGCGGTATCGCCTTTGAAGTTCTGACGTTCTCC
CTTGCCAATGCATCTGCTGACAAGCTGGAGGGAATGAAGGCGCTTCTTGAAAAGCGTAAAGCGAATTTTCAAGACAAGTA
G

Upstream 100 bases:

>100_bases
AACAATGGACGTCCGCTGGAATCCCCCTCTATCCATCAAACTGCTGCTGAAATCAGGCAGGCTGGGTCGCAAAAACGGCG
CCGGCTGGTACAAGTACTAA

Downstream 100 bases:

>100_bases
GCTTCTATTCCTTAAAAGACGATTCGGAAGGGAAGCCTGATCTGGAAACCGGATTTCTCCCTGAAATTCAACATCCTGGA
AATTTCAGCGTATCTGTTTA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIILDSTGDKAFAAGADVKEMVNL
TPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCEMAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVG
AARAKELILTGDMIDAATAERIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS
LANASADKLEGMKALLEKRKANFQDK

Sequences:

>Translated_266_residues
MTGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIILDSTGDKAFAAGADVKEMVNL
TPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCEMAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVG
AARAKELILTGDMIDAATAERIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS
LANASADKLEGMKALLEKRKANFQDK
>Mature_265_residues
TGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIILDSTGDKAFAAGADVKEMVNLT
PVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCEMAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVGA
ARAKELILTGDMIDAATAERIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFSL
ANASADKLEGMKALLEKRKANFQDK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=261, Percent_Identity=42.5287356321839, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI4502327, Length=250, Percent_Identity=36.8, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI68989263, Length=212, Percent_Identity=32.0754716981132, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI20127408, Length=198, Percent_Identity=35.3535353535354, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI150378541, Length=252, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI31542718, Length=229, Percent_Identity=32.7510917030568, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=26.3636363636364, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=26.3636363636364, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=26.3636363636364, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI261878539, Length=114, Percent_Identity=39.4736842105263, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI70995211, Length=242, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI62530384, Length=225, Percent_Identity=25.7777777777778, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI213417737, Length=217, Percent_Identity=26.7281105990783, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI157694516, Length=217, Percent_Identity=26.7281105990783, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI37594469, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI37594471, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157694520, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI295842266, Length=223, Percent_Identity=24.2152466367713, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI25453481, Length=263, Percent_Identity=24.3346007604563, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI51538573, Length=263, Percent_Identity=24.3346007604563, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4757968, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI49355787, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4757966, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI51538581, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI221136756, Length=236, Percent_Identity=25, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI221136753, Length=236, Percent_Identity=25, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787659, Length=265, Percent_Identity=35.0943396226415, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=32.6848249027237, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=29.8850574712644, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=38.0710659898477, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=33.206106870229, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=30.1526717557252, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790281, Length=215, Percent_Identity=34.8837209302326, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=37.8378378378378, Blast_Score=171, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=38.0566801619433, Blast_Score=166, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17540714, Length=240, Percent_Identity=37.0833333333333, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17558304, Length=190, Percent_Identity=33.1578947368421, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25144276, Length=184, Percent_Identity=35.3260869565217, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=184, Percent_Identity=35.3260869565217, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=184, Percent_Identity=35.3260869565217, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=218, Percent_Identity=26.1467889908257, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=251, Percent_Identity=26.2948207171315, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=264, Percent_Identity=24.6212121212121, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=25.9090909090909, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=208, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=44.0613026819923, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=44.0613026819923, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=38.4905660377359, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24650670, Length=257, Percent_Identity=31.5175097276265, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24583165, Length=190, Percent_Identity=28.4210526315789, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357171, Length=239, Percent_Identity=30.5439330543933, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19921018, Length=186, Percent_Identity=29.5698924731183, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571730, Length=267, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571729, Length=267, Percent_Identity=29.2134831460674, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922422, Length=263, Percent_Identity=24.3346007604563, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920382, Length=212, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45550169, Length=145, Percent_Identity=31.7241379310345, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654903, Length=212, Percent_Identity=21.6981132075472, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28057; Mature: 27926

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIIL
CCCCCCEEEEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
DSTGDKAFAAGADVKEMVNLTPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCE
ECCCCCEEECCCCHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHCEECCCCCC
MAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVGAARAKELILTGDMIDAATAE
EEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHH
RIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCEEEHHHHH
LANASADKLEGMKALLEKRKANFQDK
HCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TGGQNLMAYETILLKIEGNIATITINRPPMNPLNSGVFRDVIAATREIEADDNVKVIIL
CCCCCEEEEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
DSTGDKAFAAGADVKEMVNLTPVEIYDFSLNFRKACECFAANPLPTIAVIKGFALGGGCE
ECCCCCEEECCCCHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHCEECCCCCC
MAMACDLRIAADNAKFGQPEINLGVTPGAGGTQRLTRLVGAARAKELILTGDMIDAATAE
EEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHH
RIGLVNKVVPLAELDAAVAALAEKLASKPKVSLKLCKSAINTAEDVDISSGIAFEVLTFS
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCEEEHHHHH
LANASADKLEGMKALLEKRKANFQDK
HCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA