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The map label for this gene is clpB [H]

Identifier: 85859726

GI number: 85859726

Start: 1954499

End: 1957123

Strand: Direct

Name: clpB [H]

Synonym: SYN_02525

Alternate gene names: 85859726

Gene position: 1954499-1957123 (Clockwise)

Preceding gene: 85859724

Following gene: 85859727

Centisome position: 61.48

GC content: 53.64

Gene sequence:

>2625_bases
ATGATTATGAGGAATCAACGCGGAGGAGAAATTATGCGTTTTGACAAATTTACCTTGAAAGTACTGGAAGGCCTTCAGGA
AGCCCAGACCCTGGCCGGAAACTACGGTCATCATGGCATCGATGTTGAGCATCTCCTGCTGGCTTTTATCGCCCAGCCGG
AAGGCATTGTGGGCAATATCCTGAAAAAACTGGGCACGGAGCCGGCACAGATAGAAAAGGAAATTAAAAAAGTTGTGGAG
CGGCTGCCCCGTATTTCGGGTCCGATTCAGTCTTATATCACCCCCAGACTGAATAAAATCCTGGATAACGCCATGACGGA
AGCAGCCCATCTCAACGATGAGTATGTCAGCGCCGAACATGTGCTGATAGCCATGGCCAACGAAAAGGAAGGGGAGGCCT
CGCGCATCCTCCGCTCTGCCGGAGTGACGCGGGACAATATCTTCAAGGTTCTCGTGGAAATCCGGGGAACCCAGAGGATC
ACGGATCCCAATCCCGAAGAAAAATATGAGGCCTTGAAGCGGTATGCCAAAGATTTCAATGAACTTGCCCGCAAAGGGGC
GTTTGACCCCGTCATCGGCAGGAACGATGAAATTCGGAGAATCATGCAGGTTCTTTCCCGGCGGACCAAGAACAATCCCG
TTCTCATCGGTGAACCCGGTGTTGGAAAGACGGCGATCGTTGAAGGGCTCGCCCAGCGCATCGTAAATGGCGATGTCCCG
GAAAGCCTGAAGAACAAACGGGTCATCGGTCTGGATATCGGAGCACTGGTAGCCGGAGCCAAGTATCGCGGCGAATTCGA
GGACCGTCTCAAGGCTGTCCTGAAGGAAGTCACCGACGCGCAGGGCGAGATCATCCTCTTCATCGATGAAATCCATACGG
TCGTCGGCGCCGGAGCAGCGGAAGGGTCCGTGGATGCATCCAACATGCTGAAGCCGGCCCTCGCTCGAGGCGAGTTACGC
TGTGTCGGGGCGACAACCCTGAACGAATACAGAAAGCATATAGAAAAAGATCCCGCGCTGGAACGGCGCTTTCAGCCCAT
ACTGGTCAGGGAGCCCACCGTGGAAGACACCATCGCCATCCTCCGGGGATTGAAGGAACGGTATGAAATCCATCACGGCG
TCCGGATCAAGGATTCCGCCATCGTCGCGGCGGCAACGCTCTCTAATCGCTACATCAGTGATCGTTTTCTTCCCGACAAG
GCTGTGGACCTGGTGGATGAGGCGGCATCCCGCCTGAGGATCGAACTGGACAGCCTGCCGGCGGAAATCGATGTTCTGGA
GAGAAAGGCTATTCAACTGGAGATCGAGCGTCAGTCCCTGAAAAATGAAACGGACCGGACATCCCTTGAAAGGAGAGAGA
AGATCGAACGGGAACTTGCCGATCTGCGGGAATCCATGAACAGCATGAAACTCCACTGGTCTGAGGAAAAGGAGGTCATA
AAAAGAATCCAGACGATCAAGAGTGATCTCGAAAACTTCAAGAATGAAGAACAAAATGCCATGCGGGAAGGCAATCTGGC
CCGGGCTGCGGAAATCCGCTACGGGAAACTGGTGGAATTGAACCGGGCGCTTGAAGAAGAACAGAATCGACTTAAAGAAA
TCCAGAAGGACAGCAAGATGCTGAAAGAAGAAGTGGATGCCGAGGATGTAGCGGAAGTCGTCGCCAACTGGACCGGCATT
CCCGTCGCCCGGATGATGGAAAGCGACATCCAGAAGCTGATTCACATGGAAGACCGGCTCAAGCAGCGTGTGATCGGACA
GGATGAAGGCATTCACGCGGTTTCCGCCGCCCTGCGTCGGGCACGTTCCGGGCTCCAGGATCCCAACCGGCCTATCGGCT
CCTTTATTTTCCTTGGCCCCACCGGCGTGGGCAAGACCGAGCTGGCCAGGGCGCTCGCGGAATTCATGTTCGATAATGAA
CAGGCCATGATCCGCATCGATATGTCGGAATACATGGAAAAGCATTCCGTCGCCCGCCTGATCGGCGCGCCTCCCGGATA
CGTTGGTTATGACGAAGGCGGCTATCTCACGGAAGCTGTCCGCCGTCGACCCTATGCGGTTCTGCTGTTCGACGAAATCG
AAAAGGCCCATCCCGATGTCTTCAACATCCTGCTGCAGATCCTTGACGACGGCCGCCTGACGGATGGCCACGGGAGAACG
GTCGATTTCAAGAACACGATCGTGATTCTGACTTCAAACGTTGGAAGCCAGTGGATTCAGGACATTACCCTGACAGCTGA
GGAGAAGCGCCTGAGGACCATGGAAATTCTGCGGGCCACTTTCAAGCCTGAATTTCTGAATCGAATCGATGACATCATCA
TCTTCCGCTCACTGACCATGACGGATCTCGAACGGATTATCGCGATTCAGATCGGTCTGATTCAGAAACGGCTTATGGAT
CGGAAGCTCTTCCTTGAATTGACAGAAAAGGCCAAAAATTATATATCCCAGGAAGGTTACAGCCCGGTGTACGGCGCGAG
ACCGTTGAAGCGGGCCCTCCAAAAGATGCTTCTCGACAATCTCTCCATGAAAATTCTGGAAGGCGCCTTTGTTGAAGGAG
ATCATATTCTCGCGGACATCGATGACCGGGGCGAAATCAATTTTACAAAGAAAAGCGGAAGCTAA

Upstream 100 bases:

>100_bases
GAGCTTCCCGCCATGGTTAATTTACGAATGAAATCCTGAGATTTCCAGACTTGGAAGTGAGCTCATTGACTTCATTTGAA
GCATTTTTTGTGTAAACACC

Downstream 100 bases:

>100_bases
AACATTTTTCCCCTTTTTCCCTCTTTTCGGGAGAGAGGGGTTTACAGGAAAACGCGGAAAATACCGAAGGAGAAAAGTGA
ATGAATACAGTTAAAACAGC

Product: clpB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MIMRNQRGGEIMRFDKFTLKVLEGLQEAQTLAGNYGHHGIDVEHLLLAFIAQPEGIVGNILKKLGTEPAQIEKEIKKVVE
RLPRISGPIQSYITPRLNKILDNAMTEAAHLNDEYVSAEHVLIAMANEKEGEASRILRSAGVTRDNIFKVLVEIRGTQRI
TDPNPEEKYEALKRYAKDFNELARKGAFDPVIGRNDEIRRIMQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVP
ESLKNKRVIGLDIGALVAGAKYRGEFEDRLKAVLKEVTDAQGEIILFIDEIHTVVGAGAAEGSVDASNMLKPALARGELR
CVGATTLNEYRKHIEKDPALERRFQPILVREPTVEDTIAILRGLKERYEIHHGVRIKDSAIVAAATLSNRYISDRFLPDK
AVDLVDEAASRLRIELDSLPAEIDVLERKAIQLEIERQSLKNETDRTSLERREKIERELADLRESMNSMKLHWSEEKEVI
KRIQTIKSDLENFKNEEQNAMREGNLARAAEIRYGKLVELNRALEEEQNRLKEIQKDSKMLKEEVDAEDVAEVVANWTGI
PVARMMESDIQKLIHMEDRLKQRVIGQDEGIHAVSAALRRARSGLQDPNRPIGSFIFLGPTGVGKTELARALAEFMFDNE
QAMIRIDMSEYMEKHSVARLIGAPPGYVGYDEGGYLTEAVRRRPYAVLLFDEIEKAHPDVFNILLQILDDGRLTDGHGRT
VDFKNTIVILTSNVGSQWIQDITLTAEEKRLRTMEILRATFKPEFLNRIDDIIIFRSLTMTDLERIIAIQIGLIQKRLMD
RKLFLELTEKAKNYISQEGYSPVYGARPLKRALQKMLLDNLSMKILEGAFVEGDHILADIDDRGEINFTKKSGS

Sequences:

>Translated_874_residues
MIMRNQRGGEIMRFDKFTLKVLEGLQEAQTLAGNYGHHGIDVEHLLLAFIAQPEGIVGNILKKLGTEPAQIEKEIKKVVE
RLPRISGPIQSYITPRLNKILDNAMTEAAHLNDEYVSAEHVLIAMANEKEGEASRILRSAGVTRDNIFKVLVEIRGTQRI
TDPNPEEKYEALKRYAKDFNELARKGAFDPVIGRNDEIRRIMQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVP
ESLKNKRVIGLDIGALVAGAKYRGEFEDRLKAVLKEVTDAQGEIILFIDEIHTVVGAGAAEGSVDASNMLKPALARGELR
CVGATTLNEYRKHIEKDPALERRFQPILVREPTVEDTIAILRGLKERYEIHHGVRIKDSAIVAAATLSNRYISDRFLPDK
AVDLVDEAASRLRIELDSLPAEIDVLERKAIQLEIERQSLKNETDRTSLERREKIERELADLRESMNSMKLHWSEEKEVI
KRIQTIKSDLENFKNEEQNAMREGNLARAAEIRYGKLVELNRALEEEQNRLKEIQKDSKMLKEEVDAEDVAEVVANWTGI
PVARMMESDIQKLIHMEDRLKQRVIGQDEGIHAVSAALRRARSGLQDPNRPIGSFIFLGPTGVGKTELARALAEFMFDNE
QAMIRIDMSEYMEKHSVARLIGAPPGYVGYDEGGYLTEAVRRRPYAVLLFDEIEKAHPDVFNILLQILDDGRLTDGHGRT
VDFKNTIVILTSNVGSQWIQDITLTAEEKRLRTMEILRATFKPEFLNRIDDIIIFRSLTMTDLERIIAIQIGLIQKRLMD
RKLFLELTEKAKNYISQEGYSPVYGARPLKRALQKMLLDNLSMKILEGAFVEGDHILADIDDRGEINFTKKSGS
>Mature_874_residues
MIMRNQRGGEIMRFDKFTLKVLEGLQEAQTLAGNYGHHGIDVEHLLLAFIAQPEGIVGNILKKLGTEPAQIEKEIKKVVE
RLPRISGPIQSYITPRLNKILDNAMTEAAHLNDEYVSAEHVLIAMANEKEGEASRILRSAGVTRDNIFKVLVEIRGTQRI
TDPNPEEKYEALKRYAKDFNELARKGAFDPVIGRNDEIRRIMQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVP
ESLKNKRVIGLDIGALVAGAKYRGEFEDRLKAVLKEVTDAQGEIILFIDEIHTVVGAGAAEGSVDASNMLKPALARGELR
CVGATTLNEYRKHIEKDPALERRFQPILVREPTVEDTIAILRGLKERYEIHHGVRIKDSAIVAAATLSNRYISDRFLPDK
AVDLVDEAASRLRIELDSLPAEIDVLERKAIQLEIERQSLKNETDRTSLERREKIERELADLRESMNSMKLHWSEEKEVI
KRIQTIKSDLENFKNEEQNAMREGNLARAAEIRYGKLVELNRALEEEQNRLKEIQKDSKMLKEEVDAEDVAEVVANWTGI
PVARMMESDIQKLIHMEDRLKQRVIGQDEGIHAVSAALRRARSGLQDPNRPIGSFIFLGPTGVGKTELARALAEFMFDNE
QAMIRIDMSEYMEKHSVARLIGAPPGYVGYDEGGYLTEAVRRRPYAVLLFDEIEKAHPDVFNILLQILDDGRLTDGHGRT
VDFKNTIVILTSNVGSQWIQDITLTAEEKRLRTMEILRATFKPEFLNRIDDIIIFRSLTMTDLERIIAIQIGLIQKRLMD
RKLFLELTEKAKNYISQEGYSPVYGARPLKRALQKMLLDNLSMKILEGAFVEGDHILADIDDRGEINFTKKSGS

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=38.5906040268456, Blast_Score=213, Evalue=5e-55,
Organism=Escherichia coli, GI1788943, Length=859, Percent_Identity=53.5506402793946, Blast_Score=913, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=443, Percent_Identity=39.9548532731377, Blast_Score=306, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6320464, Length=710, Percent_Identity=51.830985915493, Blast_Score=756, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=877, Percent_Identity=42.30330672748, Blast_Score=671, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 98840; Mature: 98840

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMRNQRGGEIMRFDKFTLKVLEGLQEAQTLAGNYGHHGIDVEHLLLAFIAQPEGIVGNI
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHH
LKKLGTEPAQIEKEIKKVVERLPRISGPIQSYITPRLNKILDNAMTEAAHLNDEYVSAEH
HHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCE
VLIAMANEKEGEASRILRSAGVTRDNIFKVLVEIRGTQRITDPNPEEKYEALKRYAKDFN
EEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ELARKGAFDPVIGRNDEIRRIMQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
ESLKNKRVIGLDIGALVAGAKYRGEFEDRLKAVLKEVTDAQGEIILFIDEIHTVVGAGAA
HHHHCCEEEEEEHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCC
EGSVDASNMLKPALARGELRCVGATTLNEYRKHIEKDPALERRFQPILVREPTVEDTIAI
CCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHCCCCEEEECCCHHHHHHH
LRGLKERYEIHHGVRIKDSAIVAAATLSNRYISDRFLPDKAVDLVDEAASRLRIELDSLP
HHHHHHHHHHHCCCEEECCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEHHHHCCC
AEIDVLERKAIQLEIERQSLKNETDRTSLERREKIERELADLRESMNSMKLHWSEEKEVI
CHHHHHHHHHHHEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHH
KRIQTIKSDLENFKNEEQNAMREGNLARAAEIRYGKLVELNRALEEEQNRLKEIQKDSKM
HHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKEEVDAEDVAEVVANWTGIPVARMMESDIQKLIHMEDRLKQRVIGQDEGIHAVSAALRR
HHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ARSGLQDPNRPIGSFIFLGPTGVGKTELARALAEFMFDNEQAMIRIDMSEYMEKHSVARL
HHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
IGAPPGYVGYDEGGYLTEAVRRRPYAVLLFDEIEKAHPDVFNILLQILDDGRLTDGHGRT
HCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCE
VDFKNTIVILTSNVGSQWIQDITLTAEEKRLRTMEILRATFKPEFLNRIDDIIIFRSLTM
EEECCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TDLERIIAIQIGLIQKRLMDRKLFLELTEKAKNYISQEGYSPVYGARPLKRALQKMLLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LSMKILEGAFVEGDHILADIDDRGEINFTKKSGS
HHHHHHHCCEECCCEEEEECCCCCCEEEECCCCC
>Mature Secondary Structure
MIMRNQRGGEIMRFDKFTLKVLEGLQEAQTLAGNYGHHGIDVEHLLLAFIAQPEGIVGNI
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHH
LKKLGTEPAQIEKEIKKVVERLPRISGPIQSYITPRLNKILDNAMTEAAHLNDEYVSAEH
HHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCE
VLIAMANEKEGEASRILRSAGVTRDNIFKVLVEIRGTQRITDPNPEEKYEALKRYAKDFN
EEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ELARKGAFDPVIGRNDEIRRIMQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
ESLKNKRVIGLDIGALVAGAKYRGEFEDRLKAVLKEVTDAQGEIILFIDEIHTVVGAGAA
HHHHCCEEEEEEHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCC
EGSVDASNMLKPALARGELRCVGATTLNEYRKHIEKDPALERRFQPILVREPTVEDTIAI
CCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHCCCCEEEECCCHHHHHHH
LRGLKERYEIHHGVRIKDSAIVAAATLSNRYISDRFLPDKAVDLVDEAASRLRIELDSLP
HHHHHHHHHHHCCCEEECCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEHHHHCCC
AEIDVLERKAIQLEIERQSLKNETDRTSLERREKIERELADLRESMNSMKLHWSEEKEVI
CHHHHHHHHHHHEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHH
KRIQTIKSDLENFKNEEQNAMREGNLARAAEIRYGKLVELNRALEEEQNRLKEIQKDSKM
HHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKEEVDAEDVAEVVANWTGIPVARMMESDIQKLIHMEDRLKQRVIGQDEGIHAVSAALRR
HHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ARSGLQDPNRPIGSFIFLGPTGVGKTELARALAEFMFDNEQAMIRIDMSEYMEKHSVARL
HHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
IGAPPGYVGYDEGGYLTEAVRRRPYAVLLFDEIEKAHPDVFNILLQILDDGRLTDGHGRT
HCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCE
VDFKNTIVILTSNVGSQWIQDITLTAEEKRLRTMEILRATFKPEFLNRIDDIIIFRSLTM
EEECCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TDLERIIAIQIGLIQKRLMDRKLFLELTEKAKNYISQEGYSPVYGARPLKRALQKMLLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LSMKILEGAFVEGDHILADIDDRGEINFTKKSGS
HHHHHHHCCEECCCEEEEECCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA