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The map label for this gene is htpX [H]

Identifier: 85859727

GI number: 85859727

Start: 1957204

End: 1958058

Strand: Direct

Name: htpX [H]

Synonym: SYN_03628

Alternate gene names: 85859727

Gene position: 1957204-1958058 (Clockwise)

Preceding gene: 85859726

Following gene: 85859728

Centisome position: 61.56

GC content: 55.67

Gene sequence:

>855_bases
ATGAATACAGTTAAAACAGCGTTGCTGCTGGGTGTCCTCACAGGACTTCTCATGCTTATCGGCGGTTTTATCGGCGGAAG
ACAGGGGGTCATGATCGCGTTCGTCTTCGCCATGATCATGAATTTCGGGAGCTACTGGTTTTCGGACAAACTGGTTCTGA
GGATGTACAATGCTCAGGAAGTATCGGAAAATCAGGCGCCGGAGCTCTACCGGCTGGTGGGAGATCTGGCCATGCGGGCT
CAACTTCCCATGCCCCGGGTCTATATTATCCCTGGAGAAACGCCCAATGCCTTCGCCACCGGGAGGAATGAACTTCATGC
CGTGGTGGCGGTTACGGAAGGTCTGCTCAGGATTCTGAACAGGGATGAGCTGGAAGGCGTCCTCGCTCATGAACTGACCC
ACATTAAAAACAAGGATATGCTTATCGGCTCCATCGCGGCCACCCTGGCGGGGGCGATCGTCATGCTCGCCAATATGGCG
CAGTGGGCAGCCATCTTCGGAGGACTGGGCGGCCGGGACAGCGATGAGGGCGAAGGAGGAGGAATCTTTGGGATGATCCT
GATGGCGATCCTTGCTCCGATTGCTGCAACGATTATCCAGATGGCCATCTCCCGTTCCCGGGAATATATGGCCGATGACG
GCGGAGCCAAAATTTCGGGGAAACCCTACGGGCTGGCCGGGGCTCTGGAGAAGCTGTCCCGCGCTTCACAGATTGTCCCC
ATGAACGCAAACCCCTCTACGGCCCATATGTTTATTGTCAATCCCCTGACTGGACGATCGCTGATGAACCTGTTCAGCAC
CCATCCGCCCATTGAGGAGCGAATCGCCAGATTGAGAAGCATGAGACCAGTATGA

Upstream 100 bases:

>100_bases
CAAAGAAAAGCGGAAGCTAAAACATTTTTCCCCTTTTTCCCTCTTTTCGGGAGAGAGGGGTTTACAGGAAAACGCGGAAA
ATACCGAAGGAGAAAAGTGA

Downstream 100 bases:

>100_bases
TCTGATGAAAGAACAACAGGATAAAAAATTTCGGCAGCATAAGGTTGGAATATTTTTGTTCAGAAATACGGTTGCAGGAG
GTTTGTATGGAGGAAGAAAA

Product: endopeptidase htpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNTVKTALLLGVLTGLLMLIGGFIGGRQGVMIAFVFAMIMNFGSYWFSDKLVLRMYNAQEVSENQAPELYRLVGDLAMRA
QLPMPRVYIIPGETPNAFATGRNELHAVVAVTEGLLRILNRDELEGVLAHELTHIKNKDMLIGSIAATLAGAIVMLANMA
QWAAIFGGLGGRDSDEGEGGGIFGMILMAILAPIAATIIQMAISRSREYMADDGGAKISGKPYGLAGALEKLSRASQIVP
MNANPSTAHMFIVNPLTGRSLMNLFSTHPPIEERIARLRSMRPV

Sequences:

>Translated_284_residues
MNTVKTALLLGVLTGLLMLIGGFIGGRQGVMIAFVFAMIMNFGSYWFSDKLVLRMYNAQEVSENQAPELYRLVGDLAMRA
QLPMPRVYIIPGETPNAFATGRNELHAVVAVTEGLLRILNRDELEGVLAHELTHIKNKDMLIGSIAATLAGAIVMLANMA
QWAAIFGGLGGRDSDEGEGGGIFGMILMAILAPIAATIIQMAISRSREYMADDGGAKISGKPYGLAGALEKLSRASQIVP
MNANPSTAHMFIVNPLTGRSLMNLFSTHPPIEERIARLRSMRPV
>Mature_284_residues
MNTVKTALLLGVLTGLLMLIGGFIGGRQGVMIAFVFAMIMNFGSYWFSDKLVLRMYNAQEVSENQAPELYRLVGDLAMRA
QLPMPRVYIIPGETPNAFATGRNELHAVVAVTEGLLRILNRDELEGVLAHELTHIKNKDMLIGSIAATLAGAIVMLANMA
QWAAIFGGLGGRDSDEGEGGGIFGMILMAILAPIAATIIQMAISRSREYMADDGGAKISGKPYGLAGALEKLSRASQIVP
MNANPSTAHMFIVNPLTGRSLMNLFSTHPPIEERIARLRSMRPV

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=288, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30599; Mature: 30599

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVKTALLLGVLTGLLMLIGGFIGGRQGVMIAFVFAMIMNFGSYWFSDKLVLRMYNAQE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHEECCHHH
VSENQAPELYRLVGDLAMRAQLPMPRVYIIPGETPNAFATGRNELHAVVAVTEGLLRILN
HCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
RDELEGVLAHELTHIKNKDMLIGSIAATLAGAIVMLANMAQWAAIFGGLGGRDSDEGEGG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GIFGMILMAILAPIAATIIQMAISRSREYMADDGGAKISGKPYGLAGALEKLSRASQIVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCEEE
MNANPSTAHMFIVNPLTGRSLMNLFSTHPPIEERIARLRSMRPV
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTVKTALLLGVLTGLLMLIGGFIGGRQGVMIAFVFAMIMNFGSYWFSDKLVLRMYNAQE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHEECCHHH
VSENQAPELYRLVGDLAMRAQLPMPRVYIIPGETPNAFATGRNELHAVVAVTEGLLRILN
HCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHC
RDELEGVLAHELTHIKNKDMLIGSIAATLAGAIVMLANMAQWAAIFGGLGGRDSDEGEGG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GIFGMILMAILAPIAATIIQMAISRSREYMADDGGAKISGKPYGLAGALEKLSRASQIVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCEEE
MNANPSTAHMFIVNPLTGRSLMNLFSTHPPIEERIARLRSMRPV
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA