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The map label for this gene is cdsA [H]

Identifier: 85859435

GI number: 85859435

Start: 1639874

End: 1640680

Strand: Direct

Name: cdsA [H]

Synonym: SYN_00917

Alternate gene names: 85859435

Gene position: 1639874-1640680 (Clockwise)

Preceding gene: 85859434

Following gene: 85859436

Centisome position: 51.58

GC content: 47.58

Gene sequence:

>807_bases
ATGACGCCGCACGTTCAACGATGGGTAACAGGATTAATTGCCGTACCGTTTCTCTTTGCGGTCATTTATTTCGGATCGGA
AACGCTGTTTGCCCTCGTGGTGGGCGCGGCCATTCTTGCGGCATGCGCTGAATATAACTTTATGGCCTTCGGGAAAGGAT
TTTCCTGGGAAAAAGGGGCGGTTATGTTCAGTGGCGCTTTTCTTCCCTCTGCGGCCTTGCTGGGAGGCGAGTCCTTGCTG
ATGGCTGCTTTCACCGCCACGATCATGATTTTTTTTCTGATCTTTCTTGGAAGCATTCATGAAGGAAAAATTACGGTCAT
TCCCGTCAGCCGGGTTTTTTTCGCCATAGTCTATATTCCTTTAATGCTCTCCTATTTTATTTTGATCCGACAATGGGAAA
ATGGTGTGTTATGGATCTTCTTCATCTTGATTCTAACGGCTTCAGGTGATATCTCCGCTTTTTATTTCGGACGGACGCTG
GGAAAGCATAAATTTTATCCCCTGGTCAGTCCGGGAAAGACGGTGGAGGGTGCCATCGGCTCTTTTGCGGGCAGCATTCT
CGCCTGTATTCTTTATAAAACCTGCGTCCTGCCCTCACTGCCTCTTTTTCACGTGCTGATTCTGGCCTGCGTCGGCAGCT
GTTTCGGTCAGTTGGGCGATCTCTGCGAGTCCGCAATTAAAAGGTCTGCAGGAGTAAAAGACTCAGGAACTATCTTTCCC
GGACATGGTGGAATTCTTGATCGGTTGGACAGCCTGATCTTTCTCGCACCTTTTGTTTATTATTATCGTATTTTTTTGAT
CGTATGA

Upstream 100 bases:

>100_bases
CAGGTTAGAGTAAATCATTACAAATCTTGAGTAATCAATCTATTATGATGGTCATGGTTTTCGGGAGGAGCAGGATACAC
ACTCGCCGATGGAATAGAAT

Downstream 100 bases:

>100_bases
AAAAGATATCTCTTCTTGGTTCCACAGGTTCCATCGGTTGCAGCGCTCTCGAAGTGATTCGCAGAAATCCGACAAAGTTT
CAGATCGTTTCATTGGCTGC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTPHVQRWVTGLIAVPFLFAVIYFGSETLFALVVGAAILAACAEYNFMAFGKGFSWEKGAVMFSGAFLPSAALLGGESLL
MAAFTATIMIFFLIFLGSIHEGKITVIPVSRVFFAIVYIPLMLSYFILIRQWENGVLWIFFILILTASGDISAFYFGRTL
GKHKFYPLVSPGKTVEGAIGSFAGSILACILYKTCVLPSLPLFHVLILACVGSCFGQLGDLCESAIKRSAGVKDSGTIFP
GHGGILDRLDSLIFLAPFVYYYRIFLIV

Sequences:

>Translated_268_residues
MTPHVQRWVTGLIAVPFLFAVIYFGSETLFALVVGAAILAACAEYNFMAFGKGFSWEKGAVMFSGAFLPSAALLGGESLL
MAAFTATIMIFFLIFLGSIHEGKITVIPVSRVFFAIVYIPLMLSYFILIRQWENGVLWIFFILILTASGDISAFYFGRTL
GKHKFYPLVSPGKTVEGAIGSFAGSILACILYKTCVLPSLPLFHVLILACVGSCFGQLGDLCESAIKRSAGVKDSGTIFP
GHGGILDRLDSLIFLAPFVYYYRIFLIV
>Mature_267_residues
TPHVQRWVTGLIAVPFLFAVIYFGSETLFALVVGAAILAACAEYNFMAFGKGFSWEKGAVMFSGAFLPSAALLGGESLLM
AAFTATIMIFFLIFLGSIHEGKITVIPVSRVFFAIVYIPLMLSYFILIRQWENGVLWIFFILILTASGDISAFYFGRTLG
KHKFYPLVSPGKTVEGAIGSFAGSILACILYKTCVLPSLPLFHVLILACVGSCFGQLGDLCESAIKRSAGVKDSGTIFPG
HGGILDRLDSLIFLAPFVYYYRIFLIV

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=155, Percent_Identity=41.2903225806452, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787677, Length=117, Percent_Identity=43.5897435897436, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29184; Mature: 29053

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHVQRWVTGLIAVPFLFAVIYFGSETLFALVVGAAILAACAEYNFMAFGKGFSWEKGA
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCC
VMFSGAFLPSAALLGGESLLMAAFTATIMIFFLIFLGSIHEGKITVIPVSRVFFAIVYIP
EEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
LMLSYFILIRQWENGVLWIFFILILTASGDISAFYFGRTLGKHKFYPLVSPGKTVEGAIG
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SFAGSILACILYKTCVLPSLPLFHVLILACVGSCFGQLGDLCESAIKRSAGVKDSGTIFP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEC
GHGGILDRLDSLIFLAPFVYYYRIFLIV
CCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPHVQRWVTGLIAVPFLFAVIYFGSETLFALVVGAAILAACAEYNFMAFGKGFSWEKGA
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCC
VMFSGAFLPSAALLGGESLLMAAFTATIMIFFLIFLGSIHEGKITVIPVSRVFFAIVYIP
EEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
LMLSYFILIRQWENGVLWIFFILILTASGDISAFYFGRTLGKHKFYPLVSPGKTVEGAIG
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
SFAGSILACILYKTCVLPSLPLFHVLILACVGSCFGQLGDLCESAIKRSAGVKDSGTIFP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEC
GHGGILDRLDSLIFLAPFVYYYRIFLIV
CCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]