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The map label for this gene is bioD [H]

Identifier: 85858050

GI number: 85858050

Start: 211332

End: 212051

Strand: Direct

Name: bioD [H]

Synonym: SYN_02569

Alternate gene names: 85858050

Gene position: 211332-212051 (Clockwise)

Preceding gene: 85858049

Following gene: 85858053

Centisome position: 6.65

GC content: 54.72

Gene sequence:

>720_bases
ATGAAAACGGAAATTCCTGACATCTATGTGATAGGCACGGATACAGGGGTCGGAAAGACCGTCCTGTCGTTCCTGTTGAT
GCGCTACTTCTTCGATCGGGGGGCTGTCCCCTTTTATTTCAAACCTGTGCAGACGGGGTGCCGTCATCCTTACGATACGG
ATTCCGATGCGAAATTCATTTATGAGAATATTCCGGAATTGAGCGGTAAGGATCCAGCCTGCTCCGTCGGATTCTGCTAT
CGAAATCCCAAGGCTCCTTTCTTTGCCGCGCGCAATGAAGGTCGCCAGGTCGACTGGCAGCGGATACTCGAAACTCTGGA
CGAAAAAAGAGCCCGTTTTGCGCCGCTGATTGTCGAAGCTGCCGGGGGCGTCTTCGTACCCATTGACGGAGAAAAGCTGG
TTATTGACACGATTCCGCCCACCGGCGCCCGCCCCCTGATTGCCGCCAGGGCCGGGTTGGGGACCATCAATCACACCCTG
TTGACGATTGCCGCCCTGGAACAGAGAAACATCGAACCCCTCGGAGTCATTCTTCTGGATGGAGGCGAGGTGGAAACGCC
GCGGGACATGATTCTGGAGAATATCGAAGCGATAGAACGGCATTCCGGCCTGCGGGTTGCCGGTGTCGTGGGCCGGATCG
CCGATTTTCAACATCTTCCTGCCGACTGTTTTAAGGGTTTGCAAATCCTGTTTGAAGGCAGGATGGGAGAACATCAGTGA

Upstream 100 bases:

>100_bases
CCCCTGGGAAGAGCCATCCTGAGGATTGGAATGACGGCCCTGCACGGGGAGGAGGACGTCAATCACTTTATTTTGTCCCT
GAAGGAGGTTATGAAAGAAT

Downstream 100 bases:

>100_bases
GGTGGAGGGTTCAGTTTGCCGTCTTCAGAAACCGGTCCTCCGACGGAAGATGATCGGAGCCGAAGCGGCAATAGGTGTTG
CGCCCTGTGCTTTTAGCCTG

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKTEIPDIYVIGTDTGVGKTVLSFLLMRYFFDRGAVPFYFKPVQTGCRHPYDTDSDAKFIYENIPELSGKDPACSVGFCY
RNPKAPFFAARNEGRQVDWQRILETLDEKRARFAPLIVEAAGGVFVPIDGEKLVIDTIPPTGARPLIAARAGLGTINHTL
LTIAALEQRNIEPLGVILLDGGEVETPRDMILENIEAIERHSGLRVAGVVGRIADFQHLPADCFKGLQILFEGRMGEHQ

Sequences:

>Translated_239_residues
MKTEIPDIYVIGTDTGVGKTVLSFLLMRYFFDRGAVPFYFKPVQTGCRHPYDTDSDAKFIYENIPELSGKDPACSVGFCY
RNPKAPFFAARNEGRQVDWQRILETLDEKRARFAPLIVEAAGGVFVPIDGEKLVIDTIPPTGARPLIAARAGLGTINHTL
LTIAALEQRNIEPLGVILLDGGEVETPRDMILENIEAIERHSGLRVAGVVGRIADFQHLPADCFKGLQILFEGRMGEHQ
>Mature_239_residues
MKTEIPDIYVIGTDTGVGKTVLSFLLMRYFFDRGAVPFYFKPVQTGCRHPYDTDSDAKFIYENIPELSGKDPACSVGFCY
RNPKAPFFAARNEGRQVDWQRILETLDEKRARFAPLIVEAAGGVFVPIDGEKLVIDTIPPTGARPLIAARAGLGTINHTL
LTIAALEQRNIEPLGVILLDGGEVETPRDMILENIEAIERHSGLRVAGVVGRIADFQHLPADCFKGLQILFEGRMGEHQ

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324385, Length=170, Percent_Identity=36.4705882352941, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26442; Mature: 26442

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEIPDIYVIGTDTGVGKTVLSFLLMRYFFDRGAVPFYFKPVQTGCRHPYDTDSDAKFI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCCCCCCCHHH
YENIPELSGKDPACSVGFCYRNPKAPFFAARNEGRQVDWQRILETLDEKRARFAPLIVEA
HHCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEC
AGGVFVPIDGEKLVIDTIPPTGARPLIAARAGLGTINHTLLTIAALEQRNIEPLGVILLD
CCCEEEEECCCEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEC
GGEVETPRDMILENIEAIERHSGLRVAGVVGRIADFQHLPADCFKGLQILFEGRMGEHQ
CCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTEIPDIYVIGTDTGVGKTVLSFLLMRYFFDRGAVPFYFKPVQTGCRHPYDTDSDAKFI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCCCCCCCHHH
YENIPELSGKDPACSVGFCYRNPKAPFFAARNEGRQVDWQRILETLDEKRARFAPLIVEA
HHCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEC
AGGVFVPIDGEKLVIDTIPPTGARPLIAARAGLGTINHTLLTIAALEQRNIEPLGVILLD
CCCEEEEECCCEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEC
GGEVETPRDMILENIEAIERHSGLRVAGVVGRIADFQHLPADCFKGLQILFEGRMGEHQ
CCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA