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The map label for this gene is rtcB [C]

Identifier: 85857851

GI number: 85857851

Start: 8263

End: 9711

Strand: Direct

Name: rtcB [C]

Synonym: SYN_02046

Alternate gene names: 85857851

Gene position: 8263-9711 (Clockwise)

Preceding gene: 85857850

Following gene: 85857852

Centisome position: 0.26

GC content: 59.01

Gene sequence:

>1449_bases
ATGTCTAAAATCAGTGTGACGCTGAACAAGCTGGATCTCTGCCGCTGGATGATCCCGAAAACCGGGGGAATGCGGGTTCC
CGGCATCATTTACACCAGCGAGGAGATGCTGCGGGAAATGGGGGATGATCAAAGTCCCCAGCAGGTCATGAATGTGGCCT
ATCTTCCTGGAATCGTGAAGTATTCTCTGGCTATGCCGGACATGCACTGGGGATATGGGTTTCCCATCGGCGGTGTGGCG
GCTTTTGATTTGAAAAACGGAGTGATTTCCCCCGGTGGGGTGGGGTACGACATCAACTGCGGCTGCCGGATGATGACCAC
GAAGCTGAACTTCGAGGATATCCGCGATCATGTGCGTGAGCTGGTGGTTGCCCTTTTTCAGAACATTCCTACCGGAGTCG
GGTCCACTGGCGTGCTCAAGCTGGCCCAGAAGGAAGAGCGCCAGGTGCTGACGCAGGGTTCCCGCTGGGCGGTGAGCCAG
GGATACGGTACGGATGAGGATGTCGAGACGACGGAAGATTACGGCGTGATGACCGGCGCCGACCCGGATAAGGTGAGCCC
CCGGGCCATGGAACGGGGGAGGGATCAACTGGGAACACTGGGATCGGGAAATCACTTTCTGGAAATCGAGGTGGTGGAAG
AAATCTTCGATCCGGATGTGGCGGCTGTCTTCGGCCTGTCCGTCGGTCAGGTGGCCGTGTTGATACATAGCGGCTCACGG
GGGCTGGGATATCAGATCTGCGATGATTACCTGGCCCGGATGGTCAAAAAAATGGGTGAACTGGGTTTTGACCTTCCCGA
CCGGCAGCTTGCCTGCTCCTGGCTGGAATCTACGGCGGGTAAGGATTACCTGGCCGCCATGGCCTGTGCAGCGAATTACG
CCTGGGCAAACCGGCAGATGCTGATGCACTGGACACGAGAAACCTTCGAGAAAACGCTGCAGAAAGCTCCCCGGGAACTC
GGCATGAAACTGCTGTACGACGTCTGCCATAATATCGCCAAACTGGAAACTTTTCCCGTGGACGGCGAGATGATGAAACT
CTGCGTGCACCGGAAGGGCGCCACCCGCTCTTTTCCTCCCGGACATCCCGCACTGCCCGAGCGCTACCGGAAAGTCGGCC
AGCCCGTGCTGATCCCCGGCGATATGGGAACCGGCTCTTACGTGATGGTCGGTACAGAAAAAGCCTATCAGGAGACCTTC
GGCAGCACCTGCCACGGCGCCGGACGGGTCATGAGCCGGGCTCAGGCGACGCGCGCCAGCGCGGGCCGGTCGGTTGCAAA
GGAAATGGCCGACCGGGGAGTAATTGTCATGGCCTCCGGCAAGGGCACCCTGAAAGAAGAAATCCCCGAAGCTTACAAAA
GGCTGGACGACGTAGTCGATGTGGTTCACCGCGCCGGCATCTCCCGCAAAGTCGCCCGCCTGCGGGCTGTGGGATGCATC
AAGGGGTAG

Upstream 100 bases:

>100_bases
TCCCGCAAACATGAGCTGATGATGGAAATCAAGGCGGTGACCTACCACCAGGCGGAAGTCGTCCGTACCCCGGAAGGGTG
GAAAGGACGGGTGATCTTCG

Downstream 100 bases:

>100_bases
TCAGGAACGACGTTATTCGGACAGACCAGACCCCCCCTTCCGGTGCGTAAACTGCTCATCGAATTTCGACTGCCATGCAG
AAGGGATTGCCAACCTGTGG

Product: RTCB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSKISVTLNKLDLCRWMIPKTGGMRVPGIIYTSEEMLREMGDDQSPQQVMNVAYLPGIVKYSLAMPDMHWGYGFPIGGVA
AFDLKNGVISPGGVGYDINCGCRMMTTKLNFEDIRDHVRELVVALFQNIPTGVGSTGVLKLAQKEERQVLTQGSRWAVSQ
GYGTDEDVETTEDYGVMTGADPDKVSPRAMERGRDQLGTLGSGNHFLEIEVVEEIFDPDVAAVFGLSVGQVAVLIHSGSR
GLGYQICDDYLARMVKKMGELGFDLPDRQLACSWLESTAGKDYLAAMACAANYAWANRQMLMHWTRETFEKTLQKAPREL
GMKLLYDVCHNIAKLETFPVDGEMMKLCVHRKGATRSFPPGHPALPERYRKVGQPVLIPGDMGTGSYVMVGTEKAYQETF
GSTCHGAGRVMSRAQATRASAGRSVAKEMADRGVIVMASGKGTLKEEIPEAYKRLDDVVDVVHRAGISRKVARLRAVGCI
KG

Sequences:

>Translated_482_residues
MSKISVTLNKLDLCRWMIPKTGGMRVPGIIYTSEEMLREMGDDQSPQQVMNVAYLPGIVKYSLAMPDMHWGYGFPIGGVA
AFDLKNGVISPGGVGYDINCGCRMMTTKLNFEDIRDHVRELVVALFQNIPTGVGSTGVLKLAQKEERQVLTQGSRWAVSQ
GYGTDEDVETTEDYGVMTGADPDKVSPRAMERGRDQLGTLGSGNHFLEIEVVEEIFDPDVAAVFGLSVGQVAVLIHSGSR
GLGYQICDDYLARMVKKMGELGFDLPDRQLACSWLESTAGKDYLAAMACAANYAWANRQMLMHWTRETFEKTLQKAPREL
GMKLLYDVCHNIAKLETFPVDGEMMKLCVHRKGATRSFPPGHPALPERYRKVGQPVLIPGDMGTGSYVMVGTEKAYQETF
GSTCHGAGRVMSRAQATRASAGRSVAKEMADRGVIVMASGKGTLKEEIPEAYKRLDDVVDVVHRAGISRKVARLRAVGCI
KG
>Mature_481_residues
SKISVTLNKLDLCRWMIPKTGGMRVPGIIYTSEEMLREMGDDQSPQQVMNVAYLPGIVKYSLAMPDMHWGYGFPIGGVAA
FDLKNGVISPGGVGYDINCGCRMMTTKLNFEDIRDHVRELVVALFQNIPTGVGSTGVLKLAQKEERQVLTQGSRWAVSQG
YGTDEDVETTEDYGVMTGADPDKVSPRAMERGRDQLGTLGSGNHFLEIEVVEEIFDPDVAAVFGLSVGQVAVLIHSGSRG
LGYQICDDYLARMVKKMGELGFDLPDRQLACSWLESTAGKDYLAAMACAANYAWANRQMLMHWTRETFEKTLQKAPRELG
MKLLYDVCHNIAKLETFPVDGEMMKLCVHRKGATRSFPPGHPALPERYRKVGQPVLIPGDMGTGSYVMVGTEKAYQETFG
STCHGAGRVMSRAQATRASAGRSVAKEMADRGVIVMASGKGTLKEEIPEAYKRLDDVVDVVHRAGISRKVARLRAVGCIK
G

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=494, Percent_Identity=45.9514170040486, Blast_Score=439, Evalue=1e-123,
Organism=Escherichia coli, GI2367224, Length=443, Percent_Identity=30.9255079006772, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17506665, Length=494, Percent_Identity=44.331983805668, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24585217, Length=490, Percent_Identity=46.9387755102041, Blast_Score=424, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 52822; Mature: 52690

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKISVTLNKLDLCRWMIPKTGGMRVPGIIYTSEEMLREMGDDQSPQQVMNVAYLPGIVK
CCCEEEEHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHH
YSLAMPDMHWGYGFPIGGVAAFDLKNGVISPGGVGYDINCGCRMMTTKLNFEDIRDHVRE
HHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEECCCCCEEEEEECCHHHHHHHHHH
LVVALFQNIPTGVGSTGVLKLAQKEERQVLTQGSRWAVSQGYGTDEDVETTEDYGVMTGA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCCCCCCC
DPDKVSPRAMERGRDQLGTLGSGNHFLEIEVVEEIFDPDVAAVFGLSVGQVAVLIHSGSR
CCCCCCHHHHHCCHHHHCCCCCCCEEEEEEEHHHHHCCCHHHHHCCCCCEEEEEEECCCC
GLGYQICDDYLARMVKKMGELGFDLPDRQLACSWLESTAGKDYLAAMACAANYAWANRQM
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHH
LMHWTRETFEKTLQKAPRELGMKLLYDVCHNIAKLETFPVDGEMMKLCVHRKGATRSFPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
GHPALPERYRKVGQPVLIPGDMGTGSYVMVGTEKAYQETFGSTCHGAGRVMSRAQATRAS
CCCCHHHHHHHHCCCEEEECCCCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AGRSVAKEMADRGVIVMASGKGTLKEEIPEAYKRLDDVVDVVHRAGISRKVARLRAVGCI
HHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
KG
CC
>Mature Secondary Structure 
SKISVTLNKLDLCRWMIPKTGGMRVPGIIYTSEEMLREMGDDQSPQQVMNVAYLPGIVK
CCEEEEHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHH
YSLAMPDMHWGYGFPIGGVAAFDLKNGVISPGGVGYDINCGCRMMTTKLNFEDIRDHVRE
HHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEECCCCCEEEEEECCHHHHHHHHHH
LVVALFQNIPTGVGSTGVLKLAQKEERQVLTQGSRWAVSQGYGTDEDVETTEDYGVMTGA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCCCCCCC
DPDKVSPRAMERGRDQLGTLGSGNHFLEIEVVEEIFDPDVAAVFGLSVGQVAVLIHSGSR
CCCCCCHHHHHCCHHHHCCCCCCCEEEEEEEHHHHHCCCHHHHHCCCCCEEEEEEECCCC
GLGYQICDDYLARMVKKMGELGFDLPDRQLACSWLESTAGKDYLAAMACAANYAWANRQM
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHH
LMHWTRETFEKTLQKAPRELGMKLLYDVCHNIAKLETFPVDGEMMKLCVHRKGATRSFPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
GHPALPERYRKVGQPVLIPGDMGTGSYVMVGTEKAYQETFGSTCHGAGRVMSRAQATRAS
CCCCHHHHHHHHCCCEEEECCCCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AGRSVAKEMADRGVIVMASGKGTLKEEIPEAYKRLDDVVDVVHRAGISRKVARLRAVGCI
HHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]