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The map label for this gene is sucC

Identifier: 85375531

GI number: 85375531

Start: 2723878

End: 2725077

Strand: Reverse

Name: sucC

Synonym: ELI_13520

Alternate gene names: 85375531

Gene position: 2725077-2723878 (Counterclockwise)

Preceding gene: 85375533

Following gene: 85375528

Centisome position: 89.28

GC content: 62.67

Gene sequence:

>1200_bases
ATGAACCTCCACGAATACCAGGCCAAGGAACTGCTTGCGAAATACGGCATCGGCATCCCCGCCGGCCACGCCGCATTGAC
CGTCGAAGAGGCGGTCGCGGGTGCCAAGCAGCTCCCCGGGCCGCTCTATGTCGTGAAGGCGCAGATCCATGCCGGCGGCC
GCGGCAAGGGCAAATTCAAGGAACTCGGCCCCGATGCGAAGGGCGGCGTGCGCTTGGCCAAGAGCATCGAGGACGTCGAA
GCCAGCGCGCGGGAGATGCTGGGCAACACGCTGGTGACCGTGCAGACGGGTGAAGAGGGCAAGCAGGTCAACCGCCTCTA
CGTCACCGACGGTGTCGACATCGCCAGCGAATACTACCTCTCGATGGTCGTCGATCGGGCTTCGGGTCGCGTCGGCATGA
TAGTGTCCACCGAAGGCGGGATGGATATCGAGGAAGTCGCCCATTCGACGCCGGAGAAGATCACCACCATCACCATCGAC
CCGGCGCAGGGCTTCATGCCGCACCACGGCCGCGCGGTGGCTTTCGCACTCAAGCTGTCGGGTGATCTCAACAAGCAGGC
GCAGAAGCTCGCCAAGCAGCTCTACACCGCCTTCATGGACCTCGATTGCGAAATGCTCGAGATCAACCCGCTCGTGGAGA
CCGAAGACGGCCAGCTTCTCGTGCTCGACACCAAGATGAGCATCGACGGCAACGCGCTCTATCGCCACAAGGACGTGGAA
GAGATGCGCGACGAGACCGAGGAAGACCCGGCCGAAGTCGAAGCCAGCGAATACGATCTCGCCTACATCAAGCTCGACGG
CAATATCGGCTGCATGGTCAACGGCGCAGGCCTCGCCATGGCGACGATGGACATCATCAAATTGAACGGCGCGTTCCCTG
CCAACTTCCTCGACGTCGGCGGCGGGGCGACGACCGAGAAGGTCACTGCGGCCTTCAAGATCATCCTCAAGGACCCGGCG
GTCGAAGGCATCCTCGTCAACATCTTCGGCGGCATCATGCGTTGCGACACGATCGCCGAGGGCATTGTAGTAGCGGCCAA
GGAAGTCGAATTGGACGTGCCGTTGGTGGTCCGCCTCGAGGGCACCAATGTCGAGAAGGGCAAGGACATCCTCGCCAATT
CGGGCCTGCCGATCGTTCCGGCGGACGATCTGGGCGACGCAGCGCGCAAGATCGTCGCCGAAGTGAAGCAGGCGGCGTAG

Upstream 100 bases:

>100_bases
CGTCAAGCCATGCTACCCGAATGGCACCTTTTCAAGCGCGACGATCCATGCTTAGGCGCGTCGCAAATCGATACCGATTC
ACGTCAACAGGATTTGCCCC

Downstream 100 bases:

>100_bases
CTTTTTGCGAAGGCGCATCCGCGCCCTCGTCCTCGGTAGATGTGCGGCAAGCCGCACCCGCTGCGGGCGCCCGGTCGGGC
TTTGACTGCCGTGACCGTGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNLHEYQAKELLAKYGIGIPAGHAALTVEEAVAGAKQLPGPLYVVKAQIHAGGRGKGKFKELGPDAKGGVRLAKSIEDVE
ASAREMLGNTLVTVQTGEEGKQVNRLYVTDGVDIASEYYLSMVVDRASGRVGMIVSTEGGMDIEEVAHSTPEKITTITID
PAQGFMPHHGRAVAFALKLSGDLNKQAQKLAKQLYTAFMDLDCEMLEINPLVETEDGQLLVLDTKMSIDGNALYRHKDVE
EMRDETEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPANFLDVGGGATTEKVTAAFKIILKDPA
VEGILVNIFGGIMRCDTIAEGIVVAAKEVELDVPLVVRLEGTNVEKGKDILANSGLPIVPADDLGDAARKIVAEVKQAA

Sequences:

>Translated_399_residues
MNLHEYQAKELLAKYGIGIPAGHAALTVEEAVAGAKQLPGPLYVVKAQIHAGGRGKGKFKELGPDAKGGVRLAKSIEDVE
ASAREMLGNTLVTVQTGEEGKQVNRLYVTDGVDIASEYYLSMVVDRASGRVGMIVSTEGGMDIEEVAHSTPEKITTITID
PAQGFMPHHGRAVAFALKLSGDLNKQAQKLAKQLYTAFMDLDCEMLEINPLVETEDGQLLVLDTKMSIDGNALYRHKDVE
EMRDETEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPANFLDVGGGATTEKVTAAFKIILKDPA
VEGILVNIFGGIMRCDTIAEGIVVAAKEVELDVPLVVRLEGTNVEKGKDILANSGLPIVPADDLGDAARKIVAEVKQAA
>Mature_399_residues
MNLHEYQAKELLAKYGIGIPAGHAALTVEEAVAGAKQLPGPLYVVKAQIHAGGRGKGKFKELGPDAKGGVRLAKSIEDVE
ASAREMLGNTLVTVQTGEEGKQVNRLYVTDGVDIASEYYLSMVVDRASGRVGMIVSTEGGMDIEEVAHSTPEKITTITID
PAQGFMPHHGRAVAFALKLSGDLNKQAQKLAKQLYTAFMDLDCEMLEINPLVETEDGQLLVLDTKMSIDGNALYRHKDVE
EMRDETEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPANFLDVGGGATTEKVTAAFKIILKDPA
VEGILVNIFGGIMRCDTIAEGIVVAAKEVELDVPLVVRLEGTNVEKGKDILANSGLPIVPADDLGDAARKIVAEVKQAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=46.4285714285714, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=48.7046632124352, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=48.0874316939891, Blast_Score=325, Evalue=6e-89,
Organism=Escherichia coli, GI1786948, Length=396, Percent_Identity=53.7878787878788, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=45.2685421994885, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=46.3291139240506, Blast_Score=334, Evalue=5e-92,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=47.3417721518987, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=49.492385786802, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=46.1340206185567, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=46.1340206185567, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=46.2724935732648, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=46.2724935732648, Blast_Score=315, Evalue=4e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_ERYLH (Q2N695)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459593.1
- HSSP:   P53590
- ProteinModelPortal:   Q2N695
- SMR:   Q2N695
- STRING:   Q2N695
- GeneID:   3869389
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_13520
- NMPDR:   fig|314225.3.peg.316
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   TDRVTLM
- PhylomeDB:   Q2N695
- ProtClustDB:   PRK00696
- BioCyc:   ELIT314225:ELI_13520-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42505; Mature: 42505

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKELLAKYGIGIPAGHAALTVEEAVAGAKQLPGPLYVVKAQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCHH
ELGPDAKGGVRLAKSIEDVEASAREMLGNTLVTVQTGEEGKQVNRLYVTDGVDIASEYYL
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHH
SMVVDRASGRVGMIVSTEGGMDIEEVAHSTPEKITTITIDPAQGFMPHHGRAVAFALKLS
HHEEECCCCCEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEC
GDLNKQAQKLAKQLYTAFMDLDCEMLEINPLVETEDGQLLVLDTKMSIDGNALYRHKDVE
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEEEEEEEECCCCCEEEECCCHH
EMRDETEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPANFLDVG
HHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCEEEEEEEEEECCCCCCCEEECC
GGATTEKVTAAFKIILKDPAVEGILVNIFGGIMRCDTIAEGIVVAAKEVELDVPLVVRLE
CCCCHHHHHHEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEC
GTNVEKGKDILANSGLPIVPADDLGDAARKIVAEVKQAA
CCCCCCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKELLAKYGIGIPAGHAALTVEEAVAGAKQLPGPLYVVKAQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCHH
ELGPDAKGGVRLAKSIEDVEASAREMLGNTLVTVQTGEEGKQVNRLYVTDGVDIASEYYL
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHH
SMVVDRASGRVGMIVSTEGGMDIEEVAHSTPEKITTITIDPAQGFMPHHGRAVAFALKLS
HHEEECCCCCEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEC
GDLNKQAQKLAKQLYTAFMDLDCEMLEINPLVETEDGQLLVLDTKMSIDGNALYRHKDVE
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEEEEEEEECCCCCEEEECCCHH
EMRDETEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPANFLDVG
HHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCEEEEEEEEEECCCCCCCEEECC
GGATTEKVTAAFKIILKDPAVEGILVNIFGGIMRCDTIAEGIVVAAKEVELDVPLVVRLE
CCCCHHHHHHEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEC
GTNVEKGKDILANSGLPIVPADDLGDAARKIVAEVKQAA
CCCCCCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA