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The map label for this gene is mcp4 [H]

Identifier: 85375074

GI number: 85375074

Start: 2271622

End: 2273025

Strand: Reverse

Name: mcp4 [H]

Synonym: ELI_11235

Alternate gene names: 85375074

Gene position: 2273025-2271622 (Counterclockwise)

Preceding gene: 85375075

Following gene: 85375073

Centisome position: 74.47

GC content: 65.1

Gene sequence:

>1404_bases
ATGAGTACGATCGAAGACCTCGCAAGCGATCTCCGGCGGGAAGCCGAGACCGAAATCGCGGCCGCATCGGACATGGTGGC
TCCGCGCATGCGCAACCCAATTGAACGGTGGTTTTCGGGCCTCGACAGCAATCAAAAACTGGTCGCTACCGGCGGCGGGC
CGATCCTGATCGTCCTGACCGTGATGGCGGTCGCATTCTGGGGCCTCGCATCGATAGAGACTGCGCCGGATGCTCAGGCC
CGGGCTGCTGCAGCAGACCTTGCCCGATGGGCTCTGCTCGGCGTCACCGGCGTCTTCGTGCTTTGTCTCGTGATCGCCGG
TCGTGTCCTGGCGCGCGATATCGTCGACACAACGCGCGGACTTGCCGATGCGATGGAGAAGATTTCTGCAGGCCAGACCG
ACTTCGACATTCCTGCCAAGGACCGGGTGGACGAATTCGGATCGATGGCGCGCTCGCTCGAGATCATGCGGCGCGGCACC
AAGCGGCTGCTGACGCTGACTGCGCGCGAGGAGCGCAACCGCGAGGAGCGCGAGAAACTGCACGAGGAACAGGAGCGTGA
AATCCTCGATCTCGCCAACACGTTCGACCGGACGGTTGGCGAAGTCGTCAGCGGCGTTGCGGCGGCATCGACCCAGCTAC
ACGCAACGGCGGGCGAAATGTCCCGCGCGGCCGAGCAGTCGACGGCCCAATCGGAACAGGTTTCGACGGCGATGGAGCGG
GCTGCGGAAGGCGCATCGGCCGCCGCCGCCGCGAGCGATGAATTCGCCATGTCCATCGGCGAGATCAGCCGTCAGGCCGC
CGATTCGGCGGAGCTGGCGCGCAAGGCGCGCGGAACGGCGGACGAAGCCGACCAGACGATCTCCGCGCTCGACCAGGCTG
CCACCTCGATCGGCCAGATCGTCGAGATGATCTCGACCATCGCCAGCCGCACCAATCTGCTTGCTCTCAACGCGTCCATC
GAAGCGGCGCGCGGCGGAGAGGCGGGACGCGGCTTTGCGGTGGTGGCTTCCGAAGTGAAGGAACTGGCCAGCCAGACCAG
CCGCGCGACGCAGGACGTTTCCGACCAGATCCAGGCTATCCAGCAATCGACCGGGGCCAGCGTTTCCGCGCTGCGCACCG
TCAGCCGCGAGATCCAGCAGATCGAAGCGACAGCCATTGCGATCGCCTCTGCGGTGGACCAGCAGTCGGTCGCAGGACAG
GATCTTGCTCGCAGCATCGACAGCGCCGCCCGCCACAGCGAGGAAGTGGGCAGCCATGTCCGCGACGTCCGCGAAAACTC
GCTTCGGACAGGTGCAGCCGCCTCGCAGGTGCTCAATTCGGCAAGCGAGCTCGAACAGCAGGCATCCACCTTGCGCGAAC
AGGTCGATGCTTTCCTTGTGAAAATTCGCGACCGGTCCAAGTAG

Upstream 100 bases:

>100_bases
AGATTCAGGGCTGGCTCTATTACCGGGCGATGCCGCCCGAACAGATCGTTGCATTGAAGGATAAATTCGGATCGACGCGG
TCCGACAGGAGCAAAGTGGC

Downstream 100 bases:

>100_bases
GCGCGCCTGCCCCCGCTCTTGCGGGGATCGCCCATTGCCTTGACGCGCCCGCTCCGGCACACTTGCGTTGCAAGTCGCAA
CGCAAACCGCCGCCGGAGAA

Product: methyl-accepting chemotaxis receptor/sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSTIEDLASDLRREAETEIAAASDMVAPRMRNPIERWFSGLDSNQKLVATGGGPILIVLTVMAVAFWGLASIETAPDAQA
RAAAADLARWALLGVTGVFVLCLVIAGRVLARDIVDTTRGLADAMEKISAGQTDFDIPAKDRVDEFGSMARSLEIMRRGT
KRLLTLTAREERNREEREKLHEEQEREILDLANTFDRTVGEVVSGVAAASTQLHATAGEMSRAAEQSTAQSEQVSTAMER
AAEGASAAAAASDEFAMSIGEISRQAADSAELARKARGTADEADQTISALDQAATSIGQIVEMISTIASRTNLLALNASI
EAARGGEAGRGFAVVASEVKELASQTSRATQDVSDQIQAIQQSTGASVSALRTVSREIQQIEATAIAIASAVDQQSVAGQ
DLARSIDSAARHSEEVGSHVRDVRENSLRTGAAASQVLNSASELEQQASTLREQVDAFLVKIRDRSK

Sequences:

>Translated_467_residues
MSTIEDLASDLRREAETEIAAASDMVAPRMRNPIERWFSGLDSNQKLVATGGGPILIVLTVMAVAFWGLASIETAPDAQA
RAAAADLARWALLGVTGVFVLCLVIAGRVLARDIVDTTRGLADAMEKISAGQTDFDIPAKDRVDEFGSMARSLEIMRRGT
KRLLTLTAREERNREEREKLHEEQEREILDLANTFDRTVGEVVSGVAAASTQLHATAGEMSRAAEQSTAQSEQVSTAMER
AAEGASAAAAASDEFAMSIGEISRQAADSAELARKARGTADEADQTISALDQAATSIGQIVEMISTIASRTNLLALNASI
EAARGGEAGRGFAVVASEVKELASQTSRATQDVSDQIQAIQQSTGASVSALRTVSREIQQIEATAIAIASAVDQQSVAGQ
DLARSIDSAARHSEEVGSHVRDVRENSLRTGAAASQVLNSASELEQQASTLREQVDAFLVKIRDRSK
>Mature_466_residues
STIEDLASDLRREAETEIAAASDMVAPRMRNPIERWFSGLDSNQKLVATGGGPILIVLTVMAVAFWGLASIETAPDAQAR
AAAADLARWALLGVTGVFVLCLVIAGRVLARDIVDTTRGLADAMEKISAGQTDFDIPAKDRVDEFGSMARSLEIMRRGTK
RLLTLTAREERNREEREKLHEEQEREILDLANTFDRTVGEVVSGVAAASTQLHATAGEMSRAAEQSTAQSEQVSTAMERA
AEGASAAAAASDEFAMSIGEISRQAADSAELARKARGTADEADQTISALDQAATSIGQIVEMISTIASRTNLLALNASIE
AARGGEAGRGFAVVASEVKELASQTSRATQDVSDQIQAIQQSTGASVSALRTVSREIQQIEATAIAIASAVDQQSVAGQD
LARSIDSAARHSEEVGSHVRDVRENSLRTGAAASQVLNSASELEQQASTLREQVDAFLVKIRDRSK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=381, Percent_Identity=27.5590551181102, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI2367378, Length=273, Percent_Identity=28.2051282051282, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788194, Length=197, Percent_Identity=34.010152284264, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788195, Length=148, Percent_Identity=33.7837837837838, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789453, Length=215, Percent_Identity=29.3023255813954, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 49536; Mature: 49405

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIEDLASDLRREAETEIAAASDMVAPRMRNPIERWFSGLDSNQKLVATGGGPILIVLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCHHHHHHH
VMAVAFWGLASIETAPDAQARAAAADLARWALLGVTGVFVLCLVIAGRVLARDIVDTTRG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADAMEKISAGQTDFDIPAKDRVDEFGSMARSLEIMRRGTKRLLTLTAREERNREEREKL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HEEQEREILDLANTFDRTVGEVVSGVAAASTQLHATAGEMSRAAEQSTAQSEQVSTAMER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEGASAAAAASDEFAMSIGEISRQAADSAELARKARGTADEADQTISALDQAATSIGQI
HHCCCHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEMISTIASRTNLLALNASIEAARGGEAGRGFAVVASEVKELASQTSRATQDVSDQIQAI
HHHHHHHHHHHCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQSTGASVSALRTVSREIQQIEATAIAIASAVDQQSVAGQDLARSIDSAARHSEEVGSHV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVRENSLRTGAAASQVLNSASELEQQASTLREQVDAFLVKIRDRSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STIEDLASDLRREAETEIAAASDMVAPRMRNPIERWFSGLDSNQKLVATGGGPILIVLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCHHHHHHH
VMAVAFWGLASIETAPDAQARAAAADLARWALLGVTGVFVLCLVIAGRVLARDIVDTTRG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADAMEKISAGQTDFDIPAKDRVDEFGSMARSLEIMRRGTKRLLTLTAREERNREEREKL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
HEEQEREILDLANTFDRTVGEVVSGVAAASTQLHATAGEMSRAAEQSTAQSEQVSTAMER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEGASAAAAASDEFAMSIGEISRQAADSAELARKARGTADEADQTISALDQAATSIGQI
HHCCCHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEMISTIASRTNLLALNASIEAARGGEAGRGFAVVASEVKELASQTSRATQDVSDQIQAI
HHHHHHHHHHHCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQSTGASVSALRTVSREIQQIEATAIAIASAVDQQSVAGQDLARSIDSAARHSEEVGSHV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVRENSLRTGAAASQVLNSASELEQQASTLREQVDAFLVKIRDRSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]