Click here to switch to the map view.

The map label for this gene is ihfA

Identifier: 85374549

GI number: 85374549

Start: 1760904

End: 1761206

Strand: Reverse

Name: ihfA

Synonym: ELI_08610

Alternate gene names: 85374549

Gene position: 1761206-1760904 (Counterclockwise)

Preceding gene: 85374551

Following gene: 85374548

Centisome position: 57.7

GC content: 59.08

Gene sequence:

>303_bases
ATGTCGCGATCGGTGGGCACGCTGACACGGGCCGATTTGGCAGAAGCGATCAATCGAAAGATGGGCTTCAGCCGTGCTGA
ATCGCTCGATATGGTCGAAGCCATTCTCGAACACATGTGCGGCGCTCTGAGGAAGGGCGAAAACGTCAAGATATCCGGCT
TCGGCAGCTTCGTGCTGCGCGACAAGAAGGAACGGATCGGCCGCAACCCCAAGACCGGCGTTGAAGTGCCGATAACTCCG
CGCCGGGTCATGACTTTCCGCGCCAGCCAGCTATTACGGGAGAGGATAGCGAAGGGAGGCTGA

Upstream 100 bases:

>100_bases
TTCTTTCCTGGCACGTTGCGATGCGGCGTGAAATCGGTTACGCATCCTATCATATGTTAAGAAAATTCGGGTCGCACCGA
CAGGAAGGGGAGGAGCGCCA

Downstream 100 bases:

>100_bases
TGTGACGACATTCGACGATGGCAAGGACGACGGCGCATTGCGCACCATCGGCGAAGTCGGGACGGCACTGGGGCTGAAAC
CGCATGTCCTGCGCTATTGG

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 100; Mature: 99

Protein sequence:

>100_residues
MSRSVGTLTRADLAEAINRKMGFSRAESLDMVEAILEHMCGALRKGENVKISGFGSFVLRDKKERIGRNPKTGVEVPITP
RRVMTFRASQLLRERIAKGG

Sequences:

>Translated_100_residues
MSRSVGTLTRADLAEAINRKMGFSRAESLDMVEAILEHMCGALRKGENVKISGFGSFVLRDKKERIGRNPKTGVEVPITP
RRVMTFRASQLLRERIAKGG
>Mature_99_residues
SRSVGTLTRADLAEAINRKMGFSRAESLDMVEAILEHMCGALRKGENVKISGFGSFVLRDKKERIGRNPKTGVEVPITPR
RVMTFRASQLLRERIAKGG

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=50.561797752809, Blast_Score=96, Evalue=4e-22,
Organism=Escherichia coli, GI1787141, Length=89, Percent_Identity=38.2022471910112, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=30.3370786516854, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_ERYLH (Q2N927)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458611.1
- ProteinModelPortal:   Q2N927
- SMR:   Q2N927
- STRING:   Q2N927
- GeneID:   3871097
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_08610
- NMPDR:   fig|314225.3.peg.1319
- eggNOG:   COG0776
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- PhylomeDB:   Q2N927
- ProtClustDB:   PRK00285
- BioCyc:   ELIT314225:ELI_08610-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11103; Mature: 10972

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSVGTLTRADLAEAINRKMGFSRAESLDMVEAILEHMCGALRKGENVKISGFGSFVLR
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHC
DKKERIGRNPKTGVEVPITPRRVMTFRASQLLRERIAKGG
CHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRSVGTLTRADLAEAINRKMGFSRAESLDMVEAILEHMCGALRKGENVKISGFGSFVLR
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHC
DKKERIGRNPKTGVEVPITPRRVMTFRASQLLRERIAKGG
CHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA