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The map label for this gene is cfa [H]

Identifier: 85374234

GI number: 85374234

Start: 1458379

End: 1459647

Strand: Reverse

Name: cfa [H]

Synonym: ELI_07035

Alternate gene names: 85374234

Gene position: 1459647-1458379 (Counterclockwise)

Preceding gene: 85374236

Following gene: 85374233

Centisome position: 47.82

GC content: 64.7

Gene sequence:

>1269_bases
ATGAATGCAGAGGGCAGCAGGAGGGGCGGCGGGCTGTTCGACGCCGCGCAGCGTTTCGAGCGCGGGCCCGGCCTGCTCGC
GCGCGTGCTCGCACCGGGCTTCCGCAAGGTGCTCGACCGGATCGATGCCGGTCTAGAGCGCGGGACCATGATCGGTCACT
TGCCCGACGGCACGACGCGGGTCCTCGGTGGGCGCGCGCCCGGCTACGAAGCCGAAGTGCACTTGCACAATTGGCGCGCG
CTGCTGCGGCTGGCTACCAACGGTTCGATCGGATGGTACCAGGCATGGGAGCAGGGCGAGTGGGAAAGCCCCGATCTCGT
GCAGGTCTTCGCGCTGTTCGGGGCCAATGCCTCTACGCTGGGCACCACCGCGCGTGCCAAGAGCATCTGGCAGCGCGCCT
TGCGCCAGGCCCATCGGCTGAACGCCAATACGCTCGAAGGTTCGCAGCGCAATATCCGCGCGCATTACGATCTCGGGAAC
GACTTCTACGCCGCCTGGCTGGGCGACACGATGACCTATTCGAGCGCGCTGTTCGGGAGGGGGGGCGAAGCAGACCTCGA
CCGTGCTCAGCATGCCAAGATCGATGCGGTTCTCGACCGTCTCGACCTCGGCGAAGGCGAAACGATGCTGGAGATCGGCT
GCGGCTGGGGCACGCTGGCGCAGGCAGCGGCGGAACGCGGGACCCGCGTCGATGCAATCAGCCTGTCCGACGAGCAATTG
GCCTGGGCCCGCGAGGGTGCGAGCGAGCAGGTGCAATTCCTGAAGCAAGACTACCGCGACACCGACGGTCCCTACGATGC
GGTCGCCAGTGTCGAGATGGTCGAGGCCCTGGGGCGTGAATTCTGGCCGACATATATGGATTGCATCGCCCGCAACCTGA
AATCGGGCGGCAAAGCGGCGCTCCAGTTCATTTCGATGCGCGACGACCTGTTCGAGGCCTACGTGAATAGCGCCGATTTC
ATCCAGGCCTACATCTTCCCCGGCGGCCTGCTGATCCGCACGAGCGAGTTCCGCCACTTGGCGGAAAAGCGCGGGCTTGC
GTGGCAGGACCAGGTCGATTTCGGGCAGGATTACGCCGAAACGCTCAGGCTGTGGCGAGAGAATTTCAACGAGGCCGTCA
GGCAGGGGCGCCTGCCCGAAGGTTTCGACGCGCGCTTTGTCGGCTTGTGGCGATACTACCTGCAATATTGCGAAGCCGGC
TTTCGCTGTGGCAGCATCGATGTACACCAAGTGACACTGGTGAAAGAGGATACGGGAGAGGACGCGTGA

Upstream 100 bases:

>100_bases
CTCCTCCCTTCGGGGCAGGCCTATCAAATTCGGGACAAGGCTCCAATCGCCGAATGGCGGGCCTTGCGAGGGGTGGCGCA
GCGCGGCATAGGCTCACTCC

Downstream 100 bases:

>100_bases
AGAAATGGATCCTGGGCGGACTGGCCGTCATCGCCGCTGCAACGGGCGTCGGCTATGCGACGCTCGACGATGACCAGAGA
GCGCTGCTGGCCAATCTCCC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNAEGSRRGGGLFDAAQRFERGPGLLARVLAPGFRKVLDRIDAGLERGTMIGHLPDGTTRVLGGRAPGYEAEVHLHNWRA
LLRLATNGSIGWYQAWEQGEWESPDLVQVFALFGANASTLGTTARAKSIWQRALRQAHRLNANTLEGSQRNIRAHYDLGN
DFYAAWLGDTMTYSSALFGRGGEADLDRAQHAKIDAVLDRLDLGEGETMLEIGCGWGTLAQAAAERGTRVDAISLSDEQL
AWAREGASEQVQFLKQDYRDTDGPYDAVASVEMVEALGREFWPTYMDCIARNLKSGGKAALQFISMRDDLFEAYVNSADF
IQAYIFPGGLLIRTSEFRHLAEKRGLAWQDQVDFGQDYAETLRLWRENFNEAVRQGRLPEGFDARFVGLWRYYLQYCEAG
FRCGSIDVHQVTLVKEDTGEDA

Sequences:

>Translated_422_residues
MNAEGSRRGGGLFDAAQRFERGPGLLARVLAPGFRKVLDRIDAGLERGTMIGHLPDGTTRVLGGRAPGYEAEVHLHNWRA
LLRLATNGSIGWYQAWEQGEWESPDLVQVFALFGANASTLGTTARAKSIWQRALRQAHRLNANTLEGSQRNIRAHYDLGN
DFYAAWLGDTMTYSSALFGRGGEADLDRAQHAKIDAVLDRLDLGEGETMLEIGCGWGTLAQAAAERGTRVDAISLSDEQL
AWAREGASEQVQFLKQDYRDTDGPYDAVASVEMVEALGREFWPTYMDCIARNLKSGGKAALQFISMRDDLFEAYVNSADF
IQAYIFPGGLLIRTSEFRHLAEKRGLAWQDQVDFGQDYAETLRLWRENFNEAVRQGRLPEGFDARFVGLWRYYLQYCEAG
FRCGSIDVHQVTLVKEDTGEDA
>Mature_422_residues
MNAEGSRRGGGLFDAAQRFERGPGLLARVLAPGFRKVLDRIDAGLERGTMIGHLPDGTTRVLGGRAPGYEAEVHLHNWRA
LLRLATNGSIGWYQAWEQGEWESPDLVQVFALFGANASTLGTTARAKSIWQRALRQAHRLNANTLEGSQRNIRAHYDLGN
DFYAAWLGDTMTYSSALFGRGGEADLDRAQHAKIDAVLDRLDLGEGETMLEIGCGWGTLAQAAAERGTRVDAISLSDEQL
AWAREGASEQVQFLKQDYRDTDGPYDAVASVEMVEALGREFWPTYMDCIARNLKSGGKAALQFISMRDDLFEAYVNSADF
IQAYIFPGGLLIRTSEFRHLAEKRGLAWQDQVDFGQDYAETLRLWRENFNEAVRQGRLPEGFDARFVGLWRYYLQYCEAG
FRCGSIDVHQVTLVKEDTGEDA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=359, Percent_Identity=30.9192200557103, Blast_Score=141, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI133904226, Length=293, Percent_Identity=38.5665529010239, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47080; Mature: 47080

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEGSRRGGGLFDAAQRFERGPGLLARVLAPGFRKVLDRIDAGLERGTMIGHLPDGTTR
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHCCHHCCCEEEECCCCCCE
VLGGRAPGYEAEVHLHNWRALLRLATNGSIGWYQAWEQGEWESPDLVQVFALFGANASTL
ECCCCCCCCCEEEEHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHH
GTTARAKSIWQRALRQAHRLNANTLEGSQRNIRAHYDLGNDFYAAWLGDTMTYSSALFGR
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEHHHHCCHHHHHHHHHCC
GGEADLDRAQHAKIDAVLDRLDLGEGETMLEIGCGWGTLAQAAAERGTRVDAISLSDEQL
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCHHHH
AWAREGASEQVQFLKQDYRDTDGPYDAVASVEMVEALGREFWPTYMDCIARNLKSGGKAA
HHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
LQFISMRDDLFEAYVNSADFIQAYIFPGGLLIRTSEFRHLAEKRGLAWQDQVDFGQDYAE
HHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEECHHHHHHHHHCCCCCCCCCCCCHHHHH
TLRLWRENFNEAVRQGRLPEGFDARFVGLWRYYLQYCEAGFRCGSIDVHQVTLVKEDTGE
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCC
DA
CC
>Mature Secondary Structure
MNAEGSRRGGGLFDAAQRFERGPGLLARVLAPGFRKVLDRIDAGLERGTMIGHLPDGTTR
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHCCHHCCCEEEECCCCCCE
VLGGRAPGYEAEVHLHNWRALLRLATNGSIGWYQAWEQGEWESPDLVQVFALFGANASTL
ECCCCCCCCCEEEEHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHH
GTTARAKSIWQRALRQAHRLNANTLEGSQRNIRAHYDLGNDFYAAWLGDTMTYSSALFGR
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEHHHHCCHHHHHHHHHCC
GGEADLDRAQHAKIDAVLDRLDLGEGETMLEIGCGWGTLAQAAAERGTRVDAISLSDEQL
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCHHHH
AWAREGASEQVQFLKQDYRDTDGPYDAVASVEMVEALGREFWPTYMDCIARNLKSGGKAA
HHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
LQFISMRDDLFEAYVNSADFIQAYIFPGGLLIRTSEFRHLAEKRGLAWQDQVDFGQDYAE
HHHHHHHHHHHHHHHCCHHHHHHEECCCCEEEECHHHHHHHHHCCCCCCCCCCCCHHHHH
TLRLWRENFNEAVRQGRLPEGFDARFVGLWRYYLQYCEAGFRCGSIDVHQVTLVKEDTGE
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCC
DA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]