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The map label for this gene is lytH [H]

Identifier: 85373878

GI number: 85373878

Start: 1086669

End: 1087364

Strand: Direct

Name: lytH [H]

Synonym: ELI_05255

Alternate gene names: 85373878

Gene position: 1086669-1087364 (Clockwise)

Preceding gene: 85373877

Following gene: 85373880

Centisome position: 35.6

GC content: 62.93

Gene sequence:

>696_bases
ATGAAGTTCCTTGATCGCATTCTCACAATAGTCATCACCGCCACGGTAACGTCGATGATCTGGATCGTCGCCGGTGGCAG
TCTGATCGAAAACGCCACGTCGGGCGACCAGATCGACCAGACGCGTCCTGCCGAGGCGGAGCCGAGCCCGTCCCCGACCG
AGGTCGAAGACGAAGATGCGGATCGTACGCCGCAACCGGGGGAATCGGCCCGCGTTCTCGACACGGAGACGGCATCGCAG
CCTACCGAGCGCGAGAATGCGCAGTTGCTGGTTCCCGTGCTCAACGTGCGCCCGAGCGATCTGTCCGACACCTTTACCGA
TGCCCGTGGCGGCGGCGTTCGCCTGCATGAGGCGATCGATATCATGGCCCCCAAGGGTACGACTGTTCGCGCGGCGGCCG
CTGGCACGATCGAAAAACTGTTCCAGTCGGCTGCCGGCGGCAAGACGATCTACGTCCGTTCGGATGATCGCAAGACCATC
CACTATTACGCGCATCTCGATGAATATGCCGAGGGACTGCGTGAAGGGCAAAAGATCAGGCGCGGTCAACGCATCGGCAC
CGTCGGATCGAGCGGCAATGCCAGCGAGGAGGCCCCGCATCTGCACTTCGCAATCCTGCGGACCACCGCCGATGCCGAAT
GGTGGGAGCCGGCCAACGCCGTCAACCCGTATCCCTTGCTGTCGGGCAGTCGCTGA

Upstream 100 bases:

>100_bases
GCTGCGTGCGCCTGACAAACTGGGATGCGGCACGGCTCAGCCAGATGGTTTCGACCGATACTGCAGTGGAATTCGTCGCG
TGATCGGCTAAGACACTTGG

Downstream 100 bases:

>100_bases
AGCCTACTGGAGCGGTCCGATACGCACGCAGCGTATCCGATCAAGCGATCCGTCGGATTTCAGTTTGCGCAGAATGGAAC
TGCCCATCCTCTTGTAGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKFLDRILTIVITATVTSMIWIVAGGSLIENATSGDQIDQTRPAEAEPSPSPTEVEDEDADRTPQPGESARVLDTETASQ
PTERENAQLLVPVLNVRPSDLSDTFTDARGGGVRLHEAIDIMAPKGTTVRAAAAGTIEKLFQSAAGGKTIYVRSDDRKTI
HYYAHLDEYAEGLREGQKIRRGQRIGTVGSSGNASEEAPHLHFAILRTTADAEWWEPANAVNPYPLLSGSR

Sequences:

>Translated_231_residues
MKFLDRILTIVITATVTSMIWIVAGGSLIENATSGDQIDQTRPAEAEPSPSPTEVEDEDADRTPQPGESARVLDTETASQ
PTERENAQLLVPVLNVRPSDLSDTFTDARGGGVRLHEAIDIMAPKGTTVRAAAAGTIEKLFQSAAGGKTIYVRSDDRKTI
HYYAHLDEYAEGLREGQKIRRGQRIGTVGSSGNASEEAPHLHFAILRTTADAEWWEPANAVNPYPLLSGSR
>Mature_231_residues
MKFLDRILTIVITATVTSMIWIVAGGSLIENATSGDQIDQTRPAEAEPSPSPTEVEDEDADRTPQPGESARVLDTETASQ
PTERENAQLLVPVLNVRPSDLSDTFTDARGGGVRLHEAIDIMAPKGTTVRAAAAGTIEKLFQSAAGGKTIYVRSDDRKTI
HYYAHLDEYAEGLREGQKIRRGQRIGTVGSSGNASEEAPHLHFAILRTTADAEWWEPANAVNPYPLLSGSR

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 24993; Mature: 24993

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDRILTIVITATVTSMIWIVAGGSLIENATSGDQIDQTRPAEAEPSPSPTEVEDEDA
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DRTPQPGESARVLDTETASQPTERENAQLLVPVLNVRPSDLSDTFTDARGGGVRLHEAID
CCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCEEEEHHHE
IMAPKGTTVRAAAAGTIEKLFQSAAGGKTIYVRSDDRKTIHYYAHLDEYAEGLREGQKIR
EECCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHH
RGQRIGTVGSSGNASEEAPHLHFAILRTTADAEWWEPANAVNPYPLLSGSR
HCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLDRILTIVITATVTSMIWIVAGGSLIENATSGDQIDQTRPAEAEPSPSPTEVEDEDA
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DRTPQPGESARVLDTETASQPTERENAQLLVPVLNVRPSDLSDTFTDARGGGVRLHEAID
CCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCEEEEHHHE
IMAPKGTTVRAAAAGTIEKLFQSAAGGKTIYVRSDDRKTIHYYAHLDEYAEGLREGQKIR
EECCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHH
RGQRIGTVGSSGNASEEAPHLHFAILRTTADAEWWEPANAVNPYPLLSGSR
HCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]