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The map label for this gene is efp

Identifier: 85373880

GI number: 85373880

Start: 1087866

End: 1088429

Strand: Direct

Name: efp

Synonym: ELI_05265

Alternate gene names: 85373880

Gene position: 1087866-1088429 (Clockwise)

Preceding gene: 85373878

Following gene: 85373881

Centisome position: 35.64

GC content: 57.98

Gene sequence:

>564_bases
ATGAAGATTAGCGGCGTGGACATCCGTCCCGGCAACATCATCGAATATGAAGGCGGCATCTGGAAAGTCGCCAAGATCCA
GCACACCCAGCCGGGCAAGGGCGGTGCCTATATGCAGGTCGAGATGAAGAACCTGCAGGACGGTCGCAAGACCAATGTTC
GCTTCCGCAGCGCCGACACGGTCGAGAAAGTACGTCTCGACACGCAGGATTACCAGTTCCTCTATGAAGACGGCGACCAG
CTCGTGTTCATGGACCAAGACACCTATGAGCAGATCAATCTCGACAGTGACCTGCTGGGCGATGCCCGTCCATTCTTGCA
GGATGGCATGACTGTCCAGCTCGAGCTGTGGGAAGAGAAACCCATCAGCGTGCAGCTGCCGCAGCAGGTGGAAGCCGATA
TCGTCGAAGCCGATGCGGTGGTAAAGGGCCAAACGGCCTCGTCCAGCTACAAGCCGGCCGTGCTCGACAATGGCGTTCGC
ATCATGGTCCCGCCGCATATCGAAAGCGGCACGCGCATTGTGGTCGATGTCTACGAGCAGACCTATGTCGGGAAGGCTGG
CTAA

Upstream 100 bases:

>100_bases
TACCACCAACCTTGCTCCGGCATGAGCGACAGGCTAGAGGGCGCGCCAGATTATGCGTCGCTTTACCGGCGCGCTCTTTC
TCACAGCAAGGCATTCACCC

Downstream 100 bases:

>100_bases
GCGTCATGTCGATGTATTCCGGCCTCATCCGGGTGATGGAAAAAGCTGCGCGCAAGGCGGGCGGAAAGCTGCGCCGCGAC
TTCGGCGAGGTCGAGCACCT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKISGVDIRPGNIIEYEGGIWKVAKIQHTQPGKGGAYMQVEMKNLQDGRKTNVRFRSADTVEKVRLDTQDYQFLYEDGDQ
LVFMDQDTYEQINLDSDLLGDARPFLQDGMTVQLELWEEKPISVQLPQQVEADIVEADAVVKGQTASSSYKPAVLDNGVR
IMVPPHIESGTRIVVDVYEQTYVGKAG

Sequences:

>Translated_187_residues
MKISGVDIRPGNIIEYEGGIWKVAKIQHTQPGKGGAYMQVEMKNLQDGRKTNVRFRSADTVEKVRLDTQDYQFLYEDGDQ
LVFMDQDTYEQINLDSDLLGDARPFLQDGMTVQLELWEEKPISVQLPQQVEADIVEADAVVKGQTASSSYKPAVLDNGVR
IMVPPHIESGTRIVVDVYEQTYVGKAG
>Mature_187_residues
MKISGVDIRPGNIIEYEGGIWKVAKIQHTQPGKGGAYMQVEMKNLQDGRKTNVRFRSADTVEKVRLDTQDYQFLYEDGDQ
LVFMDQDTYEQINLDSDLLGDARPFLQDGMTVQLELWEEKPISVQLPQQVEADIVEADAVVKGQTASSSYKPAVLDNGVR
IMVPPHIESGTRIVVDVYEQTYVGKAG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=179, Percent_Identity=34.0782122905028, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=30.9782608695652, Blast_Score=97, Evalue=5e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ERYLH (Q2NAZ6)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457942.1
- ProteinModelPortal:   Q2NAZ6
- SMR:   Q2NAZ6
- STRING:   Q2NAZ6
- GeneID:   3869150
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_05265
- NMPDR:   fig|314225.3.peg.2014
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q2NAZ6
- ProtClustDB:   PRK00529
- BioCyc:   ELIT314225:ELI_05265-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20967; Mature: 20967

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISGVDIRPGNIIEYEGGIWKVAKIQHTQPGKGGAYMQVEMKNLQDGRKTNVRFRSADT
CCCCCEEECCCCEEEECCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEECCCC
VEKVRLDTQDYQFLYEDGDQLVFMDQDTYEQINLDSDLLGDARPFLQDGMTVQLELWEEK
CEEEECCCCCEEEEEECCCEEEEEECCCCEEECCCHHHCCCCCHHHHCCCEEEEEEECCC
PISVQLPQQVEADIVEADAVVKGQTASSSYKPAVLDNGVRIMVPPHIESGTRIVVDVYEQ
CCEEECCCHHCCEEEECCEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEEECC
TYVGKAG
EECCCCC
>Mature Secondary Structure
MKISGVDIRPGNIIEYEGGIWKVAKIQHTQPGKGGAYMQVEMKNLQDGRKTNVRFRSADT
CCCCCEEECCCCEEEECCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEECCCC
VEKVRLDTQDYQFLYEDGDQLVFMDQDTYEQINLDSDLLGDARPFLQDGMTVQLELWEEK
CEEEECCCCCEEEEEECCCEEEEEECCCCEEECCCHHHCCCCCHHHHCCCEEEEEEECCC
PISVQLPQQVEADIVEADAVVKGQTASSSYKPAVLDNGVRIMVPPHIESGTRIVVDVYEQ
CCEEECCCHHCCEEEECCEEEECCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEEECC
TYVGKAG
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA