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The map label for this gene is rnc [H]

Identifier: 85373795

GI number: 85373795

Start: 998612

End: 999283

Strand: Reverse

Name: rnc [H]

Synonym: ELI_04840

Alternate gene names: 85373795

Gene position: 999283-998612 (Counterclockwise)

Preceding gene: 85373796

Following gene: 85373794

Centisome position: 32.74

GC content: 66.96

Gene sequence:

>672_bases
ATGACGATTCTCGCACCCGAAACCCTGCAATGGCTCGCCGATACCGGTTTCGCGGTGGAAGACGACGAGCTGTGGCTGGA
AGCCTTGACGCACGGCAGCACCGGGGCCGAGCGGGACTACCAGCGGCTCGAATTCCTCGGCGACCGGGTGCTGGGGCTGG
CGATCTCCGACCACCTTTTTCGCAAGGTCGGCGGATCGGAAGGCGCACTGGCGCAGCGCCTGAACGCGCTCGTCAGCAAG
GGCGCCTGCGCCAAGATCGGGCGACGGATCGGGCTGAGCGACCACCTGGTGCTCGGCAAGCAGGCGCGCGAGGATGGGGC
GGCGCAGAGCACCAACATTCTCGGAGACGTGGTCGAGGCGCTGCTCGGCGCGAATTATCTCGATGCCGGTTTCGGGCCGA
CCTGCGCGCTGGTCCACCTCCTGTGGGACGAGGATCTGAACGGCATGGCGGGCCGCTCGAAACATCCCAAGTCGGCGCTG
CAGGAATGGGCCGCGGGCAACCAGCGGCGGCCCCCGCAATACGAGCTGGTCGACCGTTCCGGCCCCGATCACGCAGCGAT
ATTCACCGTGCGGGTCGAGGTCCACAAGGTCGGCGCGGCGGAAGCGACCGCCAGCAGCAAGCAGGAAGCCGAGACCGAGG
CAGCGAAGAAATTCATGGAGCAGTTCGGGTGA

Upstream 100 bases:

>100_bases
GGGCGCGCCGCGTCCTGTTCTCGACCGATGGCGGCGCCGAATGGCTCAAGCCCTGGACATGGTTCACGGCAGCTCGCGGC
GAGCGTATGGGGAACGCCCT

Downstream 100 bases:

>100_bases
TCCCTCGACTGGACTTCTCGACAAGGCCTTGCAGGCTCGCTCGAAGTCCGCTCGGGACGAACGGGGTCATTGACTGCCGT
TCATCTCGAGCAGCAGCCGA

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTILAPETLQWLADTGFAVEDDELWLEALTHGSTGAERDYQRLEFLGDRVLGLAISDHLFRKVGGSEGALAQRLNALVSK
GACAKIGRRIGLSDHLVLGKQAREDGAAQSTNILGDVVEALLGANYLDAGFGPTCALVHLLWDEDLNGMAGRSKHPKSAL
QEWAAGNQRRPPQYELVDRSGPDHAAIFTVRVEVHKVGAAEATASSKQEAETEAAKKFMEQFG

Sequences:

>Translated_223_residues
MTILAPETLQWLADTGFAVEDDELWLEALTHGSTGAERDYQRLEFLGDRVLGLAISDHLFRKVGGSEGALAQRLNALVSK
GACAKIGRRIGLSDHLVLGKQAREDGAAQSTNILGDVVEALLGANYLDAGFGPTCALVHLLWDEDLNGMAGRSKHPKSAL
QEWAAGNQRRPPQYELVDRSGPDHAAIFTVRVEVHKVGAAEATASSKQEAETEAAKKFMEQFG
>Mature_222_residues
TILAPETLQWLADTGFAVEDDELWLEALTHGSTGAERDYQRLEFLGDRVLGLAISDHLFRKVGGSEGALAQRLNALVSKG
ACAKIGRRIGLSDHLVLGKQAREDGAAQSTNILGDVVEALLGANYLDAGFGPTCALVHLLWDEDLNGMAGRSKHPKSALQ
EWAAGNQRRPPQYELVDRSGPDHAAIFTVRVEVHKVGAAEATASSKQEAETEAAKKFMEQFG

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=182, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137682, Length=209, Percent_Identity=31.1004784688995, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 24032; Mature: 23901

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILAPETLQWLADTGFAVEDDELWLEALTHGSTGAERDYQRLEFLGDRVLGLAISDHLF
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RKVGGSEGALAQRLNALVSKGACAKIGRRIGLSDHLVLGKQAREDGAAQSTNILGDVVEA
HHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCHHHHCCCHHHHHHHHHHHHH
LLGANYLDAGFGPTCALVHLLWDEDLNGMAGRSKHPKSALQEWAAGNQRRPPQYELVDRS
HHCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCC
GPDHAAIFTVRVEVHKVGAAEATASSKQEAETEAAKKFMEQFG
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TILAPETLQWLADTGFAVEDDELWLEALTHGSTGAERDYQRLEFLGDRVLGLAISDHLF
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RKVGGSEGALAQRLNALVSKGACAKIGRRIGLSDHLVLGKQAREDGAAQSTNILGDVVEA
HHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCHHHHCCCHHHHHHHHHHHHH
LLGANYLDAGFGPTCALVHLLWDEDLNGMAGRSKHPKSALQEWAAGNQRRPPQYELVDRS
HHCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCC
GPDHAAIFTVRVEVHKVGAAEATASSKQEAETEAAKKFMEQFG
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA