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The map label for this gene is frr

Identifier: 85373585

GI number: 85373585

Start: 784982

End: 785539

Strand: Direct

Name: frr

Synonym: ELI_03790

Alternate gene names: 85373585

Gene position: 784982-785539 (Clockwise)

Preceding gene: 85373584

Following gene: 85373586

Centisome position: 25.72

GC content: 62.9

Gene sequence:

>558_bases
ATGGCGAAATACGACAAGGCCGATATCGAGCGCCGCATGGCGGGCGCGGTCGAAAGCCTCAAGAGCGATCTTTCCGGCCT
GCGCACGGGCCGTGCCAACACCAGCCTGCTCGATCCCGTGGTGGTCGAGGTCTATGGCGCGATGATGCCGCTCAACCAGG
TCGCGACGGTCAATGCGCCCGAGCCGCGCATGCTCGCGGTGCAGGTGTGGGACAAGGCCAATGTCTCGGCGGTCGAGAAA
GGTATCACAAAGGCCAATCTCGGCCTCAACCCGATGACCGATGGGCAAACGGTGCGCCTGCCGATGCCCGACCTGACCGA
GGAACGGCGCAAGGAGCTCGCCAAACTCGCGGGCCAGTATGCCGAGAAGGCCAAGATCGCCATCCGCAACGTCCGCCGCG
ACGGGATGGAAGACCTGAAGGCCGACGAAAAGGCCAAGGACATCTCCGAAGACGACCGCAAGCGGATGGAGGACGAGGTC
CAGAAGCTGACCGACAAATATGTCGCCGAAGCCGATTCCGCCGCCGAGGCGAAGGAAAAGGAAATCATGACGCAGTGA

Upstream 100 bases:

>100_bases
CCGCGAGAAGGGTAACCTGGCCCGTGTCCTCGCCGGCGAGGGTGTGCAGACGGTCGTGCAGAATTGAGATAGAACAAGAG
TTTGCAAGGGGAAGTTTGAG

Downstream 100 bases:

>100_bases
GGGGTTTTGCGATTTCCCCTCAGCCGTTCGGGCTGAGCCTGTCGAAGCCCTGTCCTTTTTCTGGCGAGCGTGTGGCTTCA
AAAGAAAGTGCAGCCCTTCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAKYDKADIERRMAGAVESLKSDLSGLRTGRANTSLLDPVVVEVYGAMMPLNQVATVNAPEPRMLAVQVWDKANVSAVEK
GITKANLGLNPMTDGQTVRLPMPDLTEERRKELAKLAGQYAEKAKIAIRNVRRDGMEDLKADEKAKDISEDDRKRMEDEV
QKLTDKYVAEADSAAEAKEKEIMTQ

Sequences:

>Translated_185_residues
MAKYDKADIERRMAGAVESLKSDLSGLRTGRANTSLLDPVVVEVYGAMMPLNQVATVNAPEPRMLAVQVWDKANVSAVEK
GITKANLGLNPMTDGQTVRLPMPDLTEERRKELAKLAGQYAEKAKIAIRNVRRDGMEDLKADEKAKDISEDDRKRMEDEV
QKLTDKYVAEADSAAEAKEKEIMTQ
>Mature_184_residues
AKYDKADIERRMAGAVESLKSDLSGLRTGRANTSLLDPVVVEVYGAMMPLNQVATVNAPEPRMLAVQVWDKANVSAVEKG
ITKANLGLNPMTDGQTVRLPMPDLTEERRKELAKLAGQYAEKAKIAIRNVRRDGMEDLKADEKAKDISEDDRKRMEDEVQ
KLTDKYVAEADSAAEAKEKEIMTQ

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=30.7262569832402, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=48.314606741573, Blast_Score=165, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ERYLH (Q2NBU1)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457647.1
- ProteinModelPortal:   Q2NBU1
- SMR:   Q2NBU1
- STRING:   Q2NBU1
- GeneID:   3871399
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_03790
- NMPDR:   fig|314225.3.peg.2320
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q2NBU1
- ProtClustDB:   PRK00083
- BioCyc:   ELIT314225:ELI_03790-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20522; Mature: 20390

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYDKADIERRMAGAVESLKSDLSGLRTGRANTSLLDPVVVEVYGAMMPLNQVATVNAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHEECCCC
EPRMLAVQVWDKANVSAVEKGITKANLGLNPMTDGQTVRLPMPDLTEERRKELAKLAGQY
CCCEEEEEECCCCCHHHHHHCCHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEKAKIAIRNVRRDGMEDLKADEKAKDISEDDRKRMEDEVQKLTDKYVAEADSAAEAKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EIMTQ
HHCCC
>Mature Secondary Structure 
AKYDKADIERRMAGAVESLKSDLSGLRTGRANTSLLDPVVVEVYGAMMPLNQVATVNAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHEECCCC
EPRMLAVQVWDKANVSAVEKGITKANLGLNPMTDGQTVRLPMPDLTEERRKELAKLAGQY
CCCEEEEEECCCCCHHHHHHCCHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AEKAKIAIRNVRRDGMEDLKADEKAKDISEDDRKRMEDEVQKLTDKYVAEADSAAEAKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EIMTQ
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA