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The map label for this gene is cycW [H]

Identifier: 85373166

GI number: 85373166

Start: 384460

End: 385119

Strand: Reverse

Name: cycW [H]

Synonym: ELI_01695

Alternate gene names: 85373166

Gene position: 385119-384460 (Counterclockwise)

Preceding gene: 85373167

Following gene: 85373163

Centisome position: 12.62

GC content: 68.79

Gene sequence:

>660_bases
ATGAGCGCGTTCGGCATCTTGCTGCGACGCGACCTCATATTGCTCCTGCCCGGAGGCTCGCGCGGCGGGGCGATCCTGCC
GCTGATCTTCTTCCTCGCCGTGGCGATGCTCTATCCGTTCGCCGTCGGGCCAGACGCGCCGCTGCTGGCGCGCACCGGTG
GTGGCGTCTTGTGGGTCGCCGCGCTGCTGGCCACGATCCTGCCGCTCGACCGCCTGGTGGCCGATGACCTGACGCATGGT
GTGTTCGACCAGTTCGCTCTGCGCGGCATTGCCGAGGAAACCGCCATGGCCAGCCGCCTCGTTGCGCATTGGCTCGCCTT
CGCTCCGCTGCTTCTGGTCGCCTGTCTCCCCGCCGCTGCGCTGCTTGGCTTGGAGGGCGACACGCTAGGTCTTCTGGTGC
TTGGACTTCTGGCAGGCACTCCGGGCCTCGCCGCCATCGGCCTCATCGTCGCCAGCCTGATGGCTAGCTTGCGCGCGGGC
GCGGCATTGGGTGGATTGCTGCTGCTGCCGCTGGCGGTGCCGATCCTGATCTTCGGCGCTGGCAGCTTGGCGCAAGGCGA
TGCGACCGGCATTGCGCTGGCTGGTGCCATCAGCCTAGCACTGTGCGGCATCGCGCCCTTCGCCGCCGGCGCAGCCATCC
GGGCTGCGCGGGAGAATTAG

Upstream 100 bases:

>100_bases
TGACCAGATTGCACTGCGGCGGCGGCGGTGTGTGTGTGATCGCTTCGCACCAGGACATCGGCATGGACGCGCACACACTC
GCAATCGAGGACTTCGCGCC

Downstream 100 bases:

>100_bases
GCATAGGGCGGCTGGTGCAGCCCCTTGGTGCTTTCCGTGAAAATCTCGATTCCGTCCTCGGTGATGCCGAGCGAATGTTC
GAACTGCGCGCTTAGCGACT

Product: ABC-type transport system permease component

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSAFGILLRRDLILLLPGGSRGGAILPLIFFLAVAMLYPFAVGPDAPLLARTGGGVLWVAALLATILPLDRLVADDLTHG
VFDQFALRGIAEETAMASRLVAHWLAFAPLLLVACLPAAALLGLEGDTLGLLVLGLLAGTPGLAAIGLIVASLMASLRAG
AALGGLLLLPLAVPILIFGAGSLAQGDATGIALAGAISLALCGIAPFAAGAAIRAAREN

Sequences:

>Translated_219_residues
MSAFGILLRRDLILLLPGGSRGGAILPLIFFLAVAMLYPFAVGPDAPLLARTGGGVLWVAALLATILPLDRLVADDLTHG
VFDQFALRGIAEETAMASRLVAHWLAFAPLLLVACLPAAALLGLEGDTLGLLVLGLLAGTPGLAAIGLIVASLMASLRAG
AALGGLLLLPLAVPILIFGAGSLAQGDATGIALAGAISLALCGIAPFAAGAAIRAAREN
>Mature_218_residues
SAFGILLRRDLILLLPGGSRGGAILPLIFFLAVAMLYPFAVGPDAPLLARTGGGVLWVAALLATILPLDRLVADDLTHGV
FDQFALRGIAEETAMASRLVAHWLAFAPLLLVACLPAAALLGLEGDTLGLLVLGLLAGTPGLAAIGLIVASLMASLRAGA
ALGGLLLLPLAVPILIFGAGSLAQGDATGIALAGAISLALCGIAPFAAGAAIRAAREN

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=35.0710900473934, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 21865; Mature: 21733

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFGILLRRDLILLLPGGSRGGAILPLIFFLAVAMLYPFAVGPDAPLLARTGGGVLWVA
CCHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHH
ALLATILPLDRLVADDLTHGVFDQFALRGIAEETAMASRLVAHWLAFAPLLLVACLPAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGLEGDTLGLLVLGLLAGTPGLAAIGLIVASLMASLRAGAALGGLLLLPLAVPILIFGA
HHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSLAQGDATGIALAGAISLALCGIAPFAAGAAIRAAREN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAFGILLRRDLILLLPGGSRGGAILPLIFFLAVAMLYPFAVGPDAPLLARTGGGVLWVA
CHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHH
ALLATILPLDRLVADDLTHGVFDQFALRGIAEETAMASRLVAHWLAFAPLLLVACLPAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGLEGDTLGLLVLGLLAGTPGLAAIGLIVASLMASLRAGAALGGLLLLPLAVPILIFGA
HHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSLAQGDATGIALAGAISLALCGIAPFAAGAAIRAAREN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]