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The map label for this gene is ccmA [H]

Identifier: 85373167

GI number: 85373167

Start: 385116

End: 385694

Strand: Reverse

Name: ccmA [H]

Synonym: ELI_01700

Alternate gene names: 85373167

Gene position: 385694-385116 (Counterclockwise)

Preceding gene: 85373169

Following gene: 85373166

Centisome position: 12.64

GC content: 65.11

Gene sequence:

>579_bases
ATGCCCGCCGCCCTCGCCGCACGCAACCTCGCCTGCCGTCGTGGCGACCGGCTCCTCTTCACCGGGCTGGAACTGGACCT
CGCTGACGGCGCGCTGCTGCATGTGACCGGCGCCAACGGCACCGGCAAATCGAGCCTGATGCGGATCCTGGCGGGATTAT
TGAGCTCTTCCGAAGGCGACGTTTCCCGAAGCGGATCGATGGCGCTGCTGGACGAACGGCTGGCGCTCGATCCCGAATGG
CCGTTGGGCAAGGCGCTTCGCTTCTGGGAGCGGCTCGACGGCTGCTCCGACCCGAGCAATATTGTCGCGATAATGGAGCT
GGAGCCACTGCTCGATGTGCCGGTGCGCTACCTTTCCACCGGCCAACGGAAGCGTGCGGCCTTCGCCCGACTGCTCTGCA
CTTCACACGACATCTGGCTGCTGGACGAACCCTTCAACGGCCTCGACATCGACGCTTGCGCCAAGGTGCGATCGCTGACC
AGATTGCACTGCGGCGGCGGCGGTGTGTGTGTGATCGCTTCGCACCAGGACATCGGCATGGACGCGCACACACTCGCAAT
CGAGGACTTCGCGCCATGA

Upstream 100 bases:

>100_bases
ATCGCGTTCTTCCTGGTTGAGTTTTCGTACGGTCATCGCGGGGCTCCTGCTTGCGGGCTACAGCTTGTGAACGCCCGACC
TTTGGCTTAGTGCCCAAGCC

Downstream 100 bases:

>100_bases
GCGCGTTCGGCATCTTGCTGCGACGCGACCTCATATTGCTCCTGCCCGGAGGCTCGCGCGGCGGGGCGATCCTGCCGCTG
ATCTTCTTCCTCGCCGTGGC

Product: ABC-type transport system ATPase component

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MPAALAARNLACRRGDRLLFTGLELDLADGALLHVTGANGTGKSSLMRILAGLLSSSEGDVSRSGSMALLDERLALDPEW
PLGKALRFWERLDGCSDPSNIVAIMELEPLLDVPVRYLSTGQRKRAAFARLLCTSHDIWLLDEPFNGLDIDACAKVRSLT
RLHCGGGGVCVIASHQDIGMDAHTLAIEDFAP

Sequences:

>Translated_192_residues
MPAALAARNLACRRGDRLLFTGLELDLADGALLHVTGANGTGKSSLMRILAGLLSSSEGDVSRSGSMALLDERLALDPEW
PLGKALRFWERLDGCSDPSNIVAIMELEPLLDVPVRYLSTGQRKRAAFARLLCTSHDIWLLDEPFNGLDIDACAKVRSLT
RLHCGGGGVCVIASHQDIGMDAHTLAIEDFAP
>Mature_191_residues
PAALAARNLACRRGDRLLFTGLELDLADGALLHVTGANGTGKSSLMRILAGLLSSSEGDVSRSGSMALLDERLALDPEWP
LGKALRFWERLDGCSDPSNIVAIMELEPLLDVPVRYLSTGQRKRAAFARLLCTSHDIWLLDEPFNGLDIDACAKVRSLTR
LHCGGGGVCVIASHQDIGMDAHTLAIEDFAP

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI87082064, Length=188, Percent_Identity=30.3191489361702, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788165, Length=156, Percent_Identity=29.4871794871795, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790467, Length=202, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI87082267, Length=190, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787758, Length=171, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87081709, Length=171, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320296, Length=147, Percent_Identity=29.9319727891156, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 20622; Mature: 20491

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAALAARNLACRRGDRLLFTGLELDLADGALLHVTGANGTGKSSLMRILAGLLSSSEGD
CCCHHHHHHHHHHCCCEEEEEECEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCC
VSRSGSMALLDERLALDPEWPLGKALRFWERLDGCSDPSNIVAIMELEPLLDVPVRYLST
CCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHCC
GQRKRAAFARLLCTSHDIWLLDEPFNGLDIDACAKVRSLTRLHCGGGGVCVIASHQDIGM
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCCC
DAHTLAIEDFAP
CEEEEEECCCCC
>Mature Secondary Structure 
PAALAARNLACRRGDRLLFTGLELDLADGALLHVTGANGTGKSSLMRILAGLLSSSEGD
CCHHHHHHHHHHCCCEEEEEECEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCC
VSRSGSMALLDERLALDPEWPLGKALRFWERLDGCSDPSNIVAIMELEPLLDVPVRYLST
CCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHCC
GQRKRAAFARLLCTSHDIWLLDEPFNGLDIDACAKVRSLTRLHCGGGGVCVIASHQDIGM
CCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCCC
DAHTLAIEDFAP
CEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA