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The map label for this gene is yjcE [H]

Identifier: 85060103

GI number: 85060103

Start: 3686009

End: 3687652

Strand: Reverse

Name: yjcE [H]

Synonym: SG2125

Alternate gene names: 85060103

Gene position: 3687652-3686009 (Counterclockwise)

Preceding gene: 85060104

Following gene: 85060099

Centisome position: 88.41

GC content: 57.24

Gene sequence:

>1644_bases
ATGGAAATCTTTTTTACGATTCTTATCCTCACTCTTATCGTGTCCCTTTCCGGGGTAGTGACACGTATCTTACCGTTTCA
AATACCGCTGCCGCTGATGCAGATAGCGCTCGGAGCGCTGCTTGCCTGGCCAAAGTTCGGCCTGCACGTGGATTTTAATC
CTGAGCTTTTCCTGGTGCTGTTTATCCCGCCGCTGTTGTTTTCCGATGGCTGGAAGACACCCACGCGCGAATTTTTGCGC
CACGGCGGCGAGATTGTGGCGCTGGCGTTGGTGTTGGTGATTATCACGGTGGTCGGTATCGGTTATCTGATTTACTGGAT
GGTGCCGGGTATCCCGCTGGTGGCGTCGCTGGCGCTGGCGGCCGTGCTATCGCCCACCGATGCGGTCGCGCTGTCGGGGA
TTGTTGGCGAAGGGCACATCCCGAAAAAGTTGATGGACATTTTGCAGGGCGAAGCACTGATGAATGACGCCTCCGGTCTG
GTGTCGCTTAAATTTGCCATCGCGGTGGCGATGGGGACGATGGTGTTTTCCGTCGGCGGCGCTTCGCTCGAGTTTGTCAA
AGTGGCGGCGGGCGGTCTGCTGGCCGGCGTGGCGGTGACCTGGGGTTACAGCAAGTCCCTGCGGCTGATTACCCGCTGGA
GCGGCGACGACGCCGCGACGCAGACGGTATTGCTGCTGCTGCTGCCGTTCGTCGCCTATCTGATCGCCGAGCATATCGGC
GTTTCCGGCATCCTGGCCGCGGTAGCCTCCGGCATGACCATCGGTCAGTCGGGCATTATCCGCAATGCGCCGCTGGCAAT
GCGGCTGCGCGGCAATAGCGTCTGGGCGATGCTGGAGTTTGTCTTCAACGGTATGGTCTTTATCATGCTGGGACTACAAC
TGCCGGACATTCTGGAGACCTCCATTACCCAGGCGGAACTGGATCCCACCATCCAGACCTGGATGCTGTTTACCGATGTC
ATTCTTATCTATGCCGCCCTGATGGTGCTGCGTTTCGGCTGGCTGTGGCTGATGAAACGCATAAGTTTGCGCTTTATGAC
CAAGCGGCCAATGGTCTTCGGCGACTATAGCACGCGCGAAATTCTGATAGCCTCTTTCGCCGGCGTGCGCGGCGCCATTA
CGCTTGCGGGCGTGTTGTCGATTCCCTTGCTGCTCAGCGACGGTTCAGCGTTTCCCTCGCGTTACCAACTGGTGTTTATC
GCCACAGGCGTGATCCTGTTTTCCCTTATCTGTGGCGTGATTGTTCTGCCGCTGCTGCTGCGCGGTATTCAGGTGTCTGA
CAAAGCGCAGCACCGTCAGGAAGAACGTATGGCCCGTGCGGCGGCGGAAGTGGCCATTGAAAGTCTGCATAAAATGGAAG
AGCGGCTGGTCAATAGCCAGGAAGAGAATATCGACAGTCAAATTCTCAACGAAGTCAGCGCCCGGGTTATCGGCAATTTA
CGCCGCCGCATTGACGGCAATGACGACGCGGACAGCGCCCTGTTGATTGAGAATCTGGAGCGGCGCATGCGGCTTAACGC
GTTGCGCGCCGAGCGCGGCGAATATTATCATTTGCGCGCGCAGCAAAAAATCAGCAATGAAACGCTGATGAAGTTACTGC
ACGATTTGGATCTGCTGGAAGCGCTGCTGGTTGAGCACGAATAG

Upstream 100 bases:

>100_bases
GCCGGGAAAATGATCTACTATCATCTCGGGGTTCGCGTTTGCGGGGAGCTATTCTCGCGCGTCCTGCACATTGCTGCAAA
AGCTAGAGACTAAGGAAAGC

Downstream 100 bases:

>100_bases
GCCGCGCCGCCGGCACGTGCCTGGGGAGCCCTTCGCGCGGGTCCTCAATCGCGCGGCAGGGACGTAACCACGTTGGTAAG
GCGAGGGCGGTTAGGTACTA

Product: putative sodium-hydrogen antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MEIFFTILILTLIVSLSGVVTRILPFQIPLPLMQIALGALLAWPKFGLHVDFNPELFLVLFIPPLLFSDGWKTPTREFLR
HGGEIVALALVLVIITVVGIGYLIYWMVPGIPLVASLALAAVLSPTDAVALSGIVGEGHIPKKLMDILQGEALMNDASGL
VSLKFAIAVAMGTMVFSVGGASLEFVKVAAGGLLAGVAVTWGYSKSLRLITRWSGDDAATQTVLLLLLPFVAYLIAEHIG
VSGILAAVASGMTIGQSGIIRNAPLAMRLRGNSVWAMLEFVFNGMVFIMLGLQLPDILETSITQAELDPTIQTWMLFTDV
ILIYAALMVLRFGWLWLMKRISLRFMTKRPMVFGDYSTREILIASFAGVRGAITLAGVLSIPLLLSDGSAFPSRYQLVFI
ATGVILFSLICGVIVLPLLLRGIQVSDKAQHRQEERMARAAAEVAIESLHKMEERLVNSQEENIDSQILNEVSARVIGNL
RRRIDGNDDADSALLIENLERRMRLNALRAERGEYYHLRAQQKISNETLMKLLHDLDLLEALLVEHE

Sequences:

>Translated_547_residues
MEIFFTILILTLIVSLSGVVTRILPFQIPLPLMQIALGALLAWPKFGLHVDFNPELFLVLFIPPLLFSDGWKTPTREFLR
HGGEIVALALVLVIITVVGIGYLIYWMVPGIPLVASLALAAVLSPTDAVALSGIVGEGHIPKKLMDILQGEALMNDASGL
VSLKFAIAVAMGTMVFSVGGASLEFVKVAAGGLLAGVAVTWGYSKSLRLITRWSGDDAATQTVLLLLLPFVAYLIAEHIG
VSGILAAVASGMTIGQSGIIRNAPLAMRLRGNSVWAMLEFVFNGMVFIMLGLQLPDILETSITQAELDPTIQTWMLFTDV
ILIYAALMVLRFGWLWLMKRISLRFMTKRPMVFGDYSTREILIASFAGVRGAITLAGVLSIPLLLSDGSAFPSRYQLVFI
ATGVILFSLICGVIVLPLLLRGIQVSDKAQHRQEERMARAAAEVAIESLHKMEERLVNSQEENIDSQILNEVSARVIGNL
RRRIDGNDDADSALLIENLERRMRLNALRAERGEYYHLRAQQKISNETLMKLLHDLDLLEALLVEHE
>Mature_547_residues
MEIFFTILILTLIVSLSGVVTRILPFQIPLPLMQIALGALLAWPKFGLHVDFNPELFLVLFIPPLLFSDGWKTPTREFLR
HGGEIVALALVLVIITVVGIGYLIYWMVPGIPLVASLALAAVLSPTDAVALSGIVGEGHIPKKLMDILQGEALMNDASGL
VSLKFAIAVAMGTMVFSVGGASLEFVKVAAGGLLAGVAVTWGYSKSLRLITRWSGDDAATQTVLLLLLPFVAYLIAEHIG
VSGILAAVASGMTIGQSGIIRNAPLAMRLRGNSVWAMLEFVFNGMVFIMLGLQLPDILETSITQAELDPTIQTWMLFTDV
ILIYAALMVLRFGWLWLMKRISLRFMTKRPMVFGDYSTREILIASFAGVRGAITLAGVLSIPLLLSDGSAFPSRYQLVFI
ATGVILFSLICGVIVLPLLLRGIQVSDKAQHRQEERMARAAAEVAIESLHKMEERLVNSQEENIDSQILNEVSARVIGNL
RRRIDGNDDADSALLIENLERRMRLNALRAERGEYYHLRAQQKISNETLMKLLHDLDLLEALLVEHE

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI15529998, Length=455, Percent_Identity=24.8351648351648, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI148727259, Length=458, Percent_Identity=23.1441048034935, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27734935, Length=266, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI14211919, Length=267, Percent_Identity=24.7191011235955, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI5454070, Length=292, Percent_Identity=23.6301369863014, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI294997330, Length=269, Percent_Identity=24.5353159851301, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI110227626, Length=269, Percent_Identity=24.5353159851301, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI41872703, Length=548, Percent_Identity=23.1751824817518, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI194239733, Length=450, Percent_Identity=24.2222222222222, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790501, Length=548, Percent_Identity=74.6350364963504, Blast_Score=823, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25150332, Length=458, Percent_Identity=22.707423580786, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71980847, Length=396, Percent_Identity=25.5050505050505, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71992107, Length=338, Percent_Identity=25.1479289940828, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71992101, Length=338, Percent_Identity=25.1479289940828, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71999817, Length=471, Percent_Identity=22.0806794055202, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999819, Length=471, Percent_Identity=22.0806794055202, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=463, Percent_Identity=22.2462203023758, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71987535, Length=478, Percent_Identity=21.9665271966527, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71987537, Length=478, Percent_Identity=21.9665271966527, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71990932, Length=396, Percent_Identity=23.4848484848485, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990924, Length=396, Percent_Identity=23.4848484848485, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147678, Length=457, Percent_Identity=25.164113785558, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320663, Length=356, Percent_Identity=24.438202247191, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221510734, Length=412, Percent_Identity=23.7864077669903, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221510738, Length=412, Percent_Identity=23.7864077669903, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221510732, Length=412, Percent_Identity=23.7864077669903, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221510736, Length=412, Percent_Identity=23.7864077669903, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221510740, Length=412, Percent_Identity=23.7864077669903, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585580, Length=412, Percent_Identity=23.7864077669903, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585578, Length=412, Percent_Identity=23.7864077669903, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 59988; Mature: 59988

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFFTILILTLIVSLSGVVTRILPFQIPLPLMQIALGALLAWPKFGLHVDFNPELFLVL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEE
FIPPLLFSDGWKTPTREFLRHGGEIVALALVLVIITVVGIGYLIYWMVPGIPLVASLALA
EHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AVLSPTDAVALSGIVGEGHIPKKLMDILQGEALMNDASGLVSLKFAIAVAMGTMVFSVGG
HHHCCCHHHHHHCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
ASLEFVKVAAGGLLAGVAVTWGYSKSLRLITRWSGDDAATQTVLLLLLPFVAYLIAEHIG
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
VSGILAAVASGMTIGQSGIIRNAPLAMRLRGNSVWAMLEFVFNGMVFIMLGLQLPDILET
HHHHHHHHHCCCCCCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
SITQAELDPTIQTWMLFTDVILIYAALMVLRFGWLWLMKRISLRFMTKRPMVFGDYSTRE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
ILIASFAGVRGAITLAGVLSIPLLLSDGSAFPSRYQLVFIATGVILFSLICGVIVLPLLL
HHHHHHHCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIQVSDKAQHRQEERMARAAAEVAIESLHKMEERLVNSQEENIDSQILNEVSARVIGNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHH
RRRIDGNDDADSALLIENLERRMRLNALRAERGEYYHLRAQQKISNETLMKLLHDLDLLE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ALLVEHE
HHHHCCC
>Mature Secondary Structure
MEIFFTILILTLIVSLSGVVTRILPFQIPLPLMQIALGALLAWPKFGLHVDFNPELFLVL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEE
FIPPLLFSDGWKTPTREFLRHGGEIVALALVLVIITVVGIGYLIYWMVPGIPLVASLALA
EHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AVLSPTDAVALSGIVGEGHIPKKLMDILQGEALMNDASGLVSLKFAIAVAMGTMVFSVGG
HHHCCCHHHHHHCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
ASLEFVKVAAGGLLAGVAVTWGYSKSLRLITRWSGDDAATQTVLLLLLPFVAYLIAEHIG
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
VSGILAAVASGMTIGQSGIIRNAPLAMRLRGNSVWAMLEFVFNGMVFIMLGLQLPDILET
HHHHHHHHHCCCCCCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
SITQAELDPTIQTWMLFTDVILIYAALMVLRFGWLWLMKRISLRFMTKRPMVFGDYSTRE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
ILIASFAGVRGAITLAGVLSIPLLLSDGSAFPSRYQLVFIATGVILFSLICGVIVLPLLL
HHHHHHHCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIQVSDKAQHRQEERMARAAAEVAIESLHKMEERLVNSQEENIDSQILNEVSARVIGNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHH
RRRIDGNDDADSALLIENLERRMRLNALRAERGEYYHLRAQQKISNETLMKLLHDLDLLE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ALLVEHE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]